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Volumn 237, Issue 2, 2014, Pages 760-766

Effective inhibition of cardiomyocyte apoptosis through the combination of trimetazidine and N-acetylcysteine in a rat model of myocardial ischemia and reperfusion injury

Author keywords

Apoptosis; M30 M65; Myocardium; N acetylcysteine; Oxidative stress; Reperfusion injury; Trimetazidine

Indexed keywords

ACETYLCYSTEINE; BIOLOGICAL MARKER; CASPASE 3; CYTOKERATIN 18; M65 PROTEIN; MALONALDEHYDE; PROTEIN S100B; SODIUM CHLORIDE; TRIMETAZIDINE; UNCLASSIFIED DRUG;

EID: 84910630607     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2014.10.091     Document Type: Article
Times cited : (29)

References (30)
  • 1
    • 0022402059 scopus 로고
    • Myocardial reperfusion: a double-edged sword?
    • Braunwald E., Kloner R.A. Myocardial reperfusion: a double-edged sword?. J.Clin. Invest 1985, 76:1713-1719.
    • (1985) J.Clin. Invest , vol.76 , pp. 1713-1719
    • Braunwald, E.1    Kloner, R.A.2
  • 3
    • 0030249340 scopus 로고    scopus 로고
    • Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart
    • Olivetti G., Quaini F., Sala R., et al. Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart. J.Mol. Cell. Cardiol. 1996, 28:2005-2016.
    • (1996) J.Mol. Cell. Cardiol. , vol.28 , pp. 2005-2016
    • Olivetti, G.1    Quaini, F.2    Sala, R.3
  • 4
    • 0030031983 scopus 로고    scopus 로고
    • Apoptotic and necrotic cell death are independent contributing variables of infarct size in rats
    • Kajstura J., Cheng W., Reiss K., et al. Apoptotic and necrotic cell death are independent contributing variables of infarct size in rats. Lab. Invest 1996, 74:86-107.
    • (1996) Lab. Invest , vol.74 , pp. 86-107
    • Kajstura, J.1    Cheng, W.2    Reiss, K.3
  • 5
    • 0034979621 scopus 로고    scopus 로고
    • Cardiomyocyte apoptosis and ventricular remodeling after myocardial infarction in rats
    • Palojoki E., Saraste A., Eriksson A., et al. Cardiomyocyte apoptosis and ventricular remodeling after myocardial infarction in rats. Am. J. Physiol. Heart Circ. Physiol. 2001, 280:H2726-H2731.
    • (2001) Am. J. Physiol. Heart Circ. Physiol. , vol.280 , pp. H2726-H2731
    • Palojoki, E.1    Saraste, A.2    Eriksson, A.3
  • 6
    • 0034678082 scopus 로고    scopus 로고
    • The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial longchain 3-ketoacyl coenzyme A thiolase
    • Kantor P.F., Lucien A., Kozak R., Lopaschuk G.D. The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial longchain 3-ketoacyl coenzyme A thiolase. Circ. Res. 2000, 86:580-588.
    • (2000) Circ. Res. , vol.86 , pp. 580-588
    • Kantor, P.F.1    Lucien, A.2    Kozak, R.3    Lopaschuk, G.D.4
  • 8
    • 0027237307 scopus 로고
    • Infarct size in rabbits: a modified method illustrated by the effects of propranolol and trimetazidine
    • Drake-Holland A.J., Belcher P.R., Hynd J., Noble M.I. Infarct size in rabbits: a modified method illustrated by the effects of propranolol and trimetazidine. Basic Res. Cardiol. 1993, 88:250-258.
    • (1993) Basic Res. Cardiol. , vol.88 , pp. 250-258
    • Drake-Holland, A.J.1    Belcher, P.R.2    Hynd, J.3    Noble, M.I.4
  • 10
    • 0014019677 scopus 로고
    • Serum-free-fatty-acids after acute myocardial infarction and cerebral vascular occlusion
    • Kurien V.A., Oliver M.F. Serum-free-fatty-acids after acute myocardial infarction and cerebral vascular occlusion. Lancet 1966, 2:122-127.
    • (1966) Lancet , vol.2 , pp. 122-127
    • Kurien, V.A.1    Oliver, M.F.2
  • 11
    • 0023936709 scopus 로고
    • The role of glutathione status in the protection against ischaemic and reperfusion damage: effects of Nacetyl cysteine
    • Ceconi C., Curello S., Cargnoni A., et al. The role of glutathione status in the protection against ischaemic and reperfusion damage: effects of Nacetyl cysteine. J.Mol. Cell. Cardiol. 1988, 20:5-13.
    • (1988) J.Mol. Cell. Cardiol. , vol.20 , pp. 5-13
    • Ceconi, C.1    Curello, S.2    Cargnoni, A.3
  • 12
    • 0028881707 scopus 로고
    • Nacetylcysteine in combination with nitroglycerin and streptokinase for the treatment of evolving acute myocardial infarction. Safety and biochemical effects
    • Arstall M.A., Yang J., Stafford I., et al. Nacetylcysteine in combination with nitroglycerin and streptokinase for the treatment of evolving acute myocardial infarction. Safety and biochemical effects. Circulation 1995, 92:2855-2862.
    • (1995) Circulation , vol.92 , pp. 2855-2862
    • Arstall, M.A.1    Yang, J.2    Stafford, I.3
  • 13
    • 0029820075 scopus 로고    scopus 로고
    • N-Acetylcysteine potentiates nitroglycerin-induced reversal of platelet aggregation
    • Chirkov Y.Y., Horowitz J.D. N-Acetylcysteine potentiates nitroglycerin-induced reversal of platelet aggregation. J.Cardiovasc Pharmacol. 1996, 28:375-380.
    • (1996) J.Cardiovasc Pharmacol. , vol.28 , pp. 375-380
    • Chirkov, Y.Y.1    Horowitz, J.D.2
  • 14
    • 0035902545 scopus 로고    scopus 로고
    • Apoptosis of endothelial cells precedes myocyte cell apoptosis in ischemia/reperfusion injury
    • Scarabelli T., Stephanou A., Rayment N., et al. Apoptosis of endothelial cells precedes myocyte cell apoptosis in ischemia/reperfusion injury. Circulation 2001, 104(3):253-256.
    • (2001) Circulation , vol.104 , Issue.3 , pp. 253-256
    • Scarabelli, T.1    Stephanou, A.2    Rayment, N.3
  • 15
    • 0029892082 scopus 로고    scopus 로고
    • Isolation, culture, and characterisation of MHC class II-positive microvascular endothelial cells from the human heart
    • McDouall R.M., Yacoub M., Rose M.L. Isolation, culture, and characterisation of MHC class II-positive microvascular endothelial cells from the human heart. Microvasc. Res. 1996, 51:137-152.
    • (1996) Microvasc. Res. , vol.51 , pp. 137-152
    • McDouall, R.M.1    Yacoub, M.2    Rose, M.L.3
  • 16
    • 34247494678 scopus 로고    scopus 로고
    • Elevated levels of interleukin-1beta-converting enzyme and caspase-cleaved cytokeratin-18 in acute myocardial infarction
    • Adlbrecht C., Hoetzenecker K., Posch M., et al. Elevated levels of interleukin-1beta-converting enzyme and caspase-cleaved cytokeratin-18 in acute myocardial infarction. Eur. J. Clin. Invest 2007, 37:372-380.
    • (2007) Eur. J. Clin. Invest , vol.37 , pp. 372-380
    • Adlbrecht, C.1    Hoetzenecker, K.2    Posch, M.3
  • 17
    • 74249085737 scopus 로고    scopus 로고
    • Changes in circulating M30 antigen, a biomarker of apoptosis, in patients with acute coronary syndromes: relationship with the severity of coronary artery disease
    • Senturk T., Aydinlar A., Yilmaz Y., et al. changes in circulating M30 antigen, a biomarker of apoptosis, in patients with acute coronary syndromes: relationship with the severity of coronary artery disease. Coron. Artery Dis. 2009, 20(8):494-498.
    • (2009) Coron. Artery Dis. , vol.20 , Issue.8 , pp. 494-498
    • Senturk, T.1    Aydinlar, A.2    Yilmaz, Y.3
  • 18
    • 0031282978 scopus 로고    scopus 로고
    • S100b inhibits beta 1-adrenergic induction of the hypertrophic phenotype in cardiac myocytes
    • 31915-31221
    • Tsoporis J.N., Marks A., Kahn H.J., et al. S100b inhibits beta 1-adrenergic induction of the hypertrophic phenotype in cardiac myocytes. J.Biol. Chem. 1997, 272. 31915-31221.
    • (1997) J.Biol. Chem. , vol.272
    • Tsoporis, J.N.1    Marks, A.2    Kahn, H.J.3
  • 19
    • 79960699904 scopus 로고    scopus 로고
    • Association of increased S100B, S100A6 and S100P in serum levels with acute coronary syndrome and also with the severity of myocardial infarction in cardiac tissue of rat models with ischemia-reperfusion injury
    • Cai X.Y., Lu L., Wang Y.N., et al. Association of increased S100B, S100A6 and S100P in serum levels with acute coronary syndrome and also with the severity of myocardial infarction in cardiac tissue of rat models with ischemia-reperfusion injury. Atherosclerosis 2011, 217:536-542.
    • (2011) Atherosclerosis , vol.217 , pp. 536-542
    • Cai, X.Y.1    Lu, L.2    Wang, Y.N.3
  • 20
    • 42349111318 scopus 로고    scopus 로고
    • Comparison of the protective effect of N-acetylcysteine by different treatments on rat myocardial ischemia-reperfusion injury
    • Abe M., Takiguchi Y., Ichimaru S., et al. Comparison of the protective effect of N-acetylcysteine by different treatments on rat myocardial ischemia-reperfusion injury. J.Pharmacol. Sci. 2008, 106:571-577.
    • (2008) J.Pharmacol. Sci. , vol.106 , pp. 571-577
    • Abe, M.1    Takiguchi, Y.2    Ichimaru, S.3
  • 21
    • 27644492930 scopus 로고    scopus 로고
    • Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia reperfusion injury
    • Argaud L., Gomez L., Gateau-Roesch O., et al. Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia reperfusion injury. J.Mol. Cell. Cardiol. 2005, 39:893-899.
    • (2005) J.Mol. Cell. Cardiol. , vol.39 , pp. 893-899
    • Argaud, L.1    Gomez, L.2    Gateau-Roesch, O.3
  • 22
    • 0028605820 scopus 로고
    • Rat and rabbit heart infarction: effects of anesthesia, perfusate, risk zone, and method of infarct sizing
    • Ytrehus K., Liu Y., Tsuchida A., et al. Rat and rabbit heart infarction: effects of anesthesia, perfusate, risk zone, and method of infarct sizing. Am. J. Physiol. 1994, 267:H2383-H2390.
    • (1994) Am. J. Physiol. , vol.267 , pp. H2383-H2390
    • Ytrehus, K.1    Liu, Y.2    Tsuchida, A.3
  • 23
    • 0025834529 scopus 로고
    • Measurement of malondialdehyde in plasma by high performance liquid chromatography with fluorimetric detection
    • Young I.S., Trimble E.R. Measurement of malondialdehyde in plasma by high performance liquid chromatography with fluorimetric detection. Ann. Clin. Biochem. 1991, 28:504-508.
    • (1991) Ann. Clin. Biochem. , vol.28 , pp. 504-508
    • Young, I.S.1    Trimble, E.R.2
  • 24
    • 33847051689 scopus 로고    scopus 로고
    • Trimetazidine inhibits cardiomyocyte apoptosis in a rabbit model of ischemia-reperfusion
    • Ruixing Y., Wenwu L., Al-Ghazeli R. Trimetazidine inhibits cardiomyocyte apoptosis in a rabbit model of ischemia-reperfusion. Transl. Res. 2007, 149(3):152-160.
    • (2007) Transl. Res. , vol.149 , Issue.3 , pp. 152-160
    • Ruixing, Y.1    Wenwu, L.2    Al-Ghazeli, R.3
  • 25
    • 0023722636 scopus 로고    scopus 로고
    • Glutathione redox pathway and reperfusion injury. Effect of N-acetylcysteine on infarct size and ventricular function
    • Forman M.B., Puett D.W., Cates C.U., et al. Glutathione redox pathway and reperfusion injury. Effect of N-acetylcysteine on infarct size and ventricular function. Circulation 1998, 78:202-213.
    • (1998) Circulation , vol.78 , pp. 202-213
    • Forman, M.B.1    Puett, D.W.2    Cates, C.U.3
  • 26
    • 84903783351 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine on apoptosis induced by myocardial ischemia reperfusion injury in rats' heart transplantation
    • Yi X., Cui X., Wu P., et al. Effects of N-acetylcysteine on apoptosis induced by myocardial ischemia reperfusion injury in rats' heart transplantation. Za Zhi 2013, 27(10):1234-1239.
    • (2013) Za Zhi , vol.27 , Issue.10 , pp. 1234-1239
    • Yi, X.1    Cui, X.2    Wu, P.3
  • 27
    • 4344635522 scopus 로고    scopus 로고
    • Protective effect of trimetazidine on rabbit myocardium during ischemia- reperfusion
    • Wang J., Huang Y.W., Wei J.H., et al. Protective effect of trimetazidine on rabbit myocardium during ischemia- reperfusion. Zhejiang Da Xue Xue Bao Yi Xue Ban 2003, 32(3):219-222.
    • (2003) Zhejiang Da Xue Xue Bao Yi Xue Ban , vol.32 , Issue.3 , pp. 219-222
    • Wang, J.1    Huang, Y.W.2    Wei, J.H.3
  • 28
    • 0014404611 scopus 로고
    • Relation between serum-free-fatty acids and arrhythmias and death after acute myocardial infarction
    • Oliver M.F., Kurien V.A., Greenwood T.W. Relation between serum-free-fatty acids and arrhythmias and death after acute myocardial infarction. Lancet 1968, 1:710-714.
    • (1968) Lancet , vol.1 , pp. 710-714
    • Oliver, M.F.1    Kurien, V.A.2    Greenwood, T.W.3
  • 29
    • 0028085284 scopus 로고
    • Effects of glucose and fatty acids on myocardial ischaemia and arrhythmias
    • Oliver M.F., Opie L.H. Effects of glucose and fatty acids on myocardial ischaemia and arrhythmias. Lancet 1994, 343:155-158.
    • (1994) Lancet , vol.343 , pp. 155-158
    • Oliver, M.F.1    Opie, L.H.2
  • 30
    • 0034704068 scopus 로고    scopus 로고
    • Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through RAGE activation
    • Huttunen H.J., Kuja-Panula J., Sorci G., et al. Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through RAGE activation. J.Biol. Chem. 2000, 275:40096-40105.
    • (2000) J.Biol. Chem. , vol.275 , pp. 40096-40105
    • Huttunen, H.J.1    Kuja-Panula, J.2    Sorci, G.3


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