Burden of diabetic foot disorders, guidelines for management and disparities in implementation in Europe: A systematic literature review

Diabetes/Metabolism Research and Reviews

Volumn 30, Issue 8, 2014, Pages 635-645

  van Acker, Kristien ^a   Léger, Philippe ^b   Hartemann, Agnes ^c   Chawla, Abhineet ^d   Siddiqui, Mohd Kashif ^d  

^a Rumst and Centre Santé des Fagnes   (Belgium)

^b CLINIQUE PASTEUR   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d HERON PVT India   (India)

Author keywords

Cost; Diabetic foot; Economic burden; Multidisciplinary foot care; Quality of life

Indexed keywords

ARTICLE; DIABETIC FOOT; DIABETIC PATIENT; DISEASE SEVERITY; FOOT CARE; FRANCE; GERMANY; HEALTH CARE COST; HEALTH DISPARITY; HEALTH STATUS; HOSPITALIZATION; HUMAN; ITALY; LEG AMPUTATION; LIMB SALVAGE; META ANALYSIS; ORTHOPEDIC SHOE; PATIENT REFERRAL; PRACTICE GUIDELINE; PRIMARY MEDICAL CARE; QUALITY OF LIFE; SECONDARY HEALTH CARE; SPAIN; SYSTEMATIC REVIEW; UNITED KINGDOM; WALKING AID; CLINICAL PRACTICE; COMPARATIVE STUDY; COST OF ILLNESS; ECONOMICS; HEALTH CARE DISPARITY; MULTIMODALITY CANCER THERAPY; PATHOPHYSIOLOGY; SEVERITY OF ILLNESS INDEX;

COMBINED MODALITY THERAPY; COST OF ILLNESS; DIABETIC FOOT; FRANCE; GERMANY; GREAT BRITAIN; HEALTH CARE COSTS; HEALTHCARE DISPARITIES; HUMANS; ITALY; PHYSICIAN'S PRACTICE PATTERNS; PRACTICE GUIDELINES AS TOPIC; QUALITY OF LIFE; SEVERITY OF ILLNESS INDEX; SPAIN;

EID: 84910615821     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.2523     Document Type: Article

References (57)

1. International Diabetes Federation. Diabetes atlas, 5th edition. http://www.idforg/diabetesatlas/2012 [cited 2012 Apr 2];Available from: URL: http://www.idf.org/diabetesatlas/
2. Boulton AJ, Vileikyte L, Ragnarson-Tennvall G, Apelqvist J. The global burden of diabetic foot disease. Lancet 2005; 366(9498): 1719-1724.
3. Deshpande AD, Harris-Hayes M, Schootman M. Epidemiology of diabetes and diabetes-related complications. Phys Ther 2008; 88(11): 1254-1264.
4. Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004; 27(5): 1047-1053.
5. Kanavos P, van den Aardweg S, Schurer W. Diabetes expenditure, burden of disease and management in 5 EU countries. LSE Health, London School of Economics; 2012 Jan.
6. International Working Group on the Diabetic Foot. Specific guidelines for the diagnosis and treatment of PAD in a diabetic patient with a foot ulcer 2011. International Working Group on the Diabetic Foot; 2012.
7. Jeffcoate W, Bakker K. World Diabetes Day: footing the bill. Lancet 2005; 365(9470): 1527.
8. Hex N, Bartlett C, Wright D, Taylor M, Varley D. Estimating the current and future costs of type 1 and type 2 diabetes in the UK, including direct health costs and indirect societal and productivity costs. Diabet Med 2012; 29(7): 855-862.
9. National Institute for Health and Clinical Excellence. Diabetic Foot Problems: Inpatient Management of Diabetic Foot Problems. CG119. National Institute for Health and Clinical Excellence: London, 2012.
10. von Ferber L, Koster I, Hauner H. Medical costs of diabetic complications total costs and excess costs by age and type of treatment results of the German CoDiM Study. Exp Clin Endocrinol Diabetes 2007; 115(2): 97-104.
11. Happich M, John J, Stamenitis S, Clouth J, Polnau D. The quality of life and economic burden of neuropathy in diabetic patients in Germany in 2002 - results from the Diabetic Microvascular Complications (DIMICO) study. Diabetes Res Clin Pract 2008; 81(2): 223-230.
12. Gordois A, Scuffham P, Shearer A. The health care costs of diabetic peripheral neuropathy in the UK. Diabet Foot 2003; 6: 62-73.
13. Girod I, Valensi P, Laforet C, Moreau-Defarges T, Guillon P, Baron F. An economic evaluation of the cost of diabetic foot ulcers: results of a retrospective study on 239 patients. Diabetes Metab 2003; 29(3): 269-277.
14. Prompers L, Huijberts M, Schaper N, et al. Resource utilisation and costs associated with the treatment of diabetic foot ulcers. Prospective data from the Eurodiale study. Diabetologia 2008; 51(10): 1826-1834.
15. Ray JA, Valentine WJ, Secnik K, et al. Review of the cost of diabetes complications in Australia, Canada, France, Germany, Italy and Spain. Curr Med Res Opin 2005; 21(10): 1617-1629.
16. Valensi P, Girod I, Baron F, Moreau-Defarges T, Guillon P. Quality of life and clinical correlates in patients with diabetic foot ulcers. Diabetes Metab 2005; 31(3 Pt 1): 263-271.
17. Boutoille D, Feraille A, Maulaz D, Krempf M. Quality of life with diabetes-associated foot complications: comparison between lower-limb amputation and chronic foot ulceration. Foot Ankle Int 2008; 29(11): 1074-1078.
18. Winkley K, Stahl D, Chalder T, Edmonds ME, Ismail K. Quality of life in people with their first diabetic foot ulcer: a prospective cohort study. J Am Podiatr Med Assoc 2009; 99(5): 406-414.
19. Garcia-Morales E, Lazaro-Martinez JL, Martinez-Hernandez D, Aragon-Sanchez J, Beneit-Montesinos JV, Gonzalez-Jurado MA. Impact of diabetic foot related complications on the health related quality of life (HRQol) of patients - a regional study in Spain. Int J Low Extrem Wounds 2011; 10(1): 6-11.
20. Nabuurs-Franssen MH, Huijberts MS, Nieuwenhuijzen Kruseman AC, Willems J, Schaper NC. Health-related quality of life of diabetic foot ulcer patients and their caregivers. Diabetologia 2005; 48(9): 1906-1910.
21. Nelson EA, O'Meara S, Craig D, et al. A series of systematic reviews to inform a decision analysis for sampling and treating infected diabetic foot ulcers. Health Technol Assess 2006; 10(12):iii-x, 1.
22. Apelqvist J, Larsson J. What is the most effective way to reduce incidence of amputation in the diabetic foot? Diabetes Metab Res Rev 2000; 16(Suppl 1): S75-S83.
23. National Institute for Health and Clinical Excellence. Prevention and management of foot problems. CG10. National Institute for Health and Clinical Excellence; 2004.
24. Scottish Intercollegiate Guidelines Network. Management of Diabetes. A National Clinical Guidance 116. Scottish Intercollegiate Guidelines Network: Scotland, 2010.
25. Haute Autorité de Santé, Department for the Assessment of Medical and Surgical Procedures. Chiropodist-Podiatrist Consultations for Preventing Foot Lesions in Diabetics. Haute Autorité de Santé: France, 2007.
26. Societe de Pathologie Infectieuse de Langue Francaise. Management of diabetic foot infections. Short text. Societe de Pathologie Infectieuse de Langue Francaise. Med Mal Infect 2007; 37(1): 1-25.
27. Agency for Quality in Medicine. National disease management guideline for type 2 diabetes foot complications. http://www.versorgungsleitliniende/themen/diabetes2/dm2_fuss/index_html 2011 August 15 [cited 2012 Apr 2];Available from: URL: http://www.versorgungsleitlinien.de/themen/diabetes2/dm2_fuss/index_html
28. Ministerio de Sanidad y Consumo. Clinical practice guideline for type 2 diabetes. http://www.guiasaludes/egpc/traduccion/ingles/diabetes/completa/apartado11/pie_diabeticohtml 2009 [cited 2012 Apr 2];Available from: URL: http://www.guiasalud.es/egpc/traduccion/ingles/diabetes/completa/apartado11/pie_diabetico.html
29. International Working Group on the Diabetic Foot. Practical guidelines on the management and prevention of the diabetic foot. http://www.iwgdforg/indexphp?option=com_content&task=view&id=28&Itemid=242012 [cited 212 Apr 2];Available from: URL: http://www.iwgdf.org/index.php?option=com_content&task=view&id=28&Itemid=24
30. Faglia E, Clerici G, Caminiti M, Quarantiello A, Gino M, Morabito A. The role of early surgical debridement and revascularization in patients with diabetes and deep foot space abscess: retrospective review of 106 patients with diabetes. J Foot Ankle Surg 2006; 45(4): 220-226.
31. Prompers L, Huijberts M, Apelqvist J, et al. Optimal organization of health care in diabetic foot disease: introduction to the Eurodiale study. Int J Low Extrem Wounds 2007; 6(1): 11-17.
32. Prompers L, Huijberts M, Apelqvist J, et al. Delivery of care to diabetic patients with foot ulcers in daily practice: results of the Eurodiale study, a prospective cohort study. Diabet Med 2008; 25(6): 700-707.
33. Morbach S. Structures of diabetic foot care. Eur Endocrine Dis 2006: 48-50.
34. Fagot-Campagna A, Fosse S, Weill A, Eschwège E, Varroud-Vial M, Simon D. Preventive/care practices for microvascular complications and determinants of practices among people treated for diabetes. The ENTRED Study, France, 2001. 2005.
35. Fosse S, Hartemann-Heurtier A, Jacqueminet S, Ha VG, Grimaldi A, Fagot-Campagna A. Incidence and characteristics of lower limb amputations in people with diabetes. Diabet Med 2009; 26(4): 391-396.
36. Richard JL, Lavigne JP, Got I, et al. Management of patients hospitalized for diabetic foot infection: results of the French OPIDIA study. Diabetes Metab 2011; 37(3): 208-215.
37. Struijs JN, Baan CA, Schellevis FG, Westert GP, van den Bos GA. Comorbidity in patients with diabetes mellitus: impact on medical health care utilization. BMC Health Serv Res 2006; 6: 84.
38. Clarke P, Gray A, Legood R, Briggs A, Holman R. The impact of diabetes-related complications on healthcare costs: results from the United Kingdom Prospective Diabetes Study (UKPDS Study No. 65). Diabet Med 2003; 20(6): 442-450.
39. Edmonds ME, Blundell MP, Morris ME, Thomas EM, Cotton LT, Watkins PJ. Improved survival of the diabetic foot: the role of a specialized foot clinic. Q J Med 1986; 60(232): 763-771.
40. Searle A, Gale L, Campbell R, et al. Reducing the burden of chronic wounds: prevention and management of the diabetic foot in the context of clinical guidelines. J Health Serv Res Policy 2008; 13(Suppl 3): 82-91.
41. International Diabetes Federation, International Working Group on the Diabetic Foot. Diabetes and foot care: time to act. 2005. Ref Type: Unpublished Work
42. Rayman G, Krishnan ST, Baker NR, Wareham AM, Rayman A. Are we underestimating diabetes-related lower-extremity amputation rates? Results and benefits of the first prospective study. Diabetes Care 2004; 27(8): 1892-1896.
43. Vamos EP, Bottle A, Edmonds ME, Valabhji J, Majeed A, Millett C. Changes in the incidence of lower extremity amputations in individuals with and without diabetes in England between 2004 and 2008. Diabetes Care 2010; 33(12): 2592-2597.
44. Alexandrescu V, Hubermont G, Coessens V, et al. Why a multidisciplinary team may represent a key factor for lowering the inferior limb loss rate in diabetic neuro-ischaemic wounds: application in a departmental institution. Acta Chir Belg 2009; 109(6): 694-700.
45. Hartemann-Heurtier A, Ha VG, Danan JP, et al. Outcome of severe diabetic foot ulcers after standardised management in a specialised unit. Diabetes Metab 2002; 28(6 Pt 1): 477-484.
46. Trautner C, Haastert B, Mauckner P, Gatcke LM, Giani G. Reduced incidence of lower-limb amputations in the diabetic population of a German city, 1990-2005: results of the Leverkusen Amputation Reduction Study (LARS). Diabetes Care 2007; 30(10): 2633-2637.
47. van Houtum WH, Rauwerda JA, Ruwaard D, Schaper NC, Bakker K. Reduction in diabetes-related lower-extremity amputations in The Netherlands: 1991-2000. Diabetes Care 2004; 27(5): 1042-1046.
48. Zayed H, Halawa M, Maillardet L, Sidhu PS, Edmonds M, Rashid H. Improving limb salvage rate in diabetic patients with critical leg ischaemia using a multidisciplinary approach. Int J Clin Pract 2009; 63(6): 855-858.
49. Hamonet J, Verdie-Kessler C, Daviet JC, et al. Evaluation of a multidisciplinary consultation of diabetic foot. Ann Phys Rehabil Med 2010; 53(5): 306-318.
50. Anichini R, Lombardo F, Caravaggi C, DeBellis A, Maggini M. Diabetic foot disease and reduction of major amputations in Italy; results of an Italian 5-year study (2001-2005). Diabetic Foot Study Group abstracts. http://dfsgorg/dfsg-annual-meeting/previous-meetings/dfsg2009-abstracts.html 2009 [cited 2012 Apr 2];Available from: URL: http://dfsg.org/dfsg-annual-meeting/previous-meetings/dfsg2009-abstracts.html
51. Sotto A, Richard JL, Combescure C, et al. Beneficial effects of implementing guidelines on microbiology and costs of infected diabetic foot ulcers. Diabetologia 2010; 53(10): 2249-2255.
52. Ortegon MM, Redekop WK, Niessen LW. Cost-effectiveness of prevention and treatment of the diabetic foot: a Markov analysis. Diabetes Care 2004; 27(4): 901-907.
53. Tennvall GR, Apelqvist J. Prevention of diabetes-related foot ulcers and amputations: a cost-utility analysis based on Markov model simulations. Diabetologia 2001; 44(11): 2077-2087.
54. Holman N, Young RJ, Jeffcoate WJ. Variation in the recorded incidence of amputation of the lower limb in England. Diabetologia 2012; 55(7): 1919-1925.
55. Akhtar S, Schaper N, Apelqvist J, Jude E. A review of the Eurodiale studies: what lessons for diabetic foot care? Curr Diab Rep 2011; 11(4): 302-309.
56. Nobels F, Debacker N, Brotons C, et al. Study rationale and design of OPTIMISE, a randomised controlled trial on the effect of benchmarking on quality of care in type 2 diabetes mellitus. Cardiovasc Diabetol 2011; 10: 82.
57. Debacker N, Nobels F, Vandenberghe H, Van CP, Scheen A, Van CV. Organization of a quality-assurance project in all Belgian multidisciplinary diabetes centres treating insulin-treated diabetes patients: 5 years' experience. Diabet Med 2008; 25(2): 179-185.