Uptake of aortic 18F-FDG is correlated with low-density lipoprotein cholesterol and leptin in a general population

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Haraguchi, Ai ^a   Hayashida, Naomi ^a   Kamasaki, Toshihiko ^a,b   Miyamoto, Izumi ^b   Usui, Toshiya ^b   Ando, Takao ^a   Abiru, Norio ^a   Yamasaki, Hironori ^a   Chiba, Kenya ^b   Kudo, Takashi ^a   Kawakami, Atsushi ^a   Takamura, Noboru ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b Nishi Isahaya Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; FLUORODEOXYGLUCOSE F 18; INSULIN; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; BIOLOGICAL MARKER; RADIOPHARMACEUTICAL AGENT;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; ASCENDING AORTA; ATHEROSCLEROSIS; BODY HEIGHT; BODY MASS; BODY WEIGHT; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INTRAABDOMINAL FAT; JAPANESE (PEOPLE); LIPID ANALYSIS; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; RADIOISOTOPE DISTRIBUTION; SEX RATIO; VERY ELDERLY; AORTA; DIAGNOSTIC USE; JAPAN; METABOLISM; MIDDLE AGED; MULTIVARIATE ANALYSIS; POSITRON EMISSION TOMOGRAPHY; PROCEDURES; SCINTISCANNING;

ADULT; AGED; AGED, 80 AND OVER; AORTA; ATHEROSCLEROSIS; BIOLOGICAL MARKERS; CHOLESTEROL, LDL; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; JAPAN; LEPTIN; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 84910607057     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0111990     Document Type: Article

References (39)

1. Nabel EG (2003) Cardiovascular disease. N Engl J Med 349:60-72.
2. Grundy SM, Cleeman JI, Merz CN, Brewer HB, Jr., Clark LT, et al. (2004) Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. J Am Coll Cardiol 44:720-732.
3. Khot UN, Khot MB, Bajzer CT, Sapp SK, Ohman EM, et al. (2003) Prevalence of conventional risk factors in patients with coronary heart disease. JAMA 290:898-904.
4. Ross R (1999) Atherosclerosis-an inflammatory disease. N Engl J Med 340:115-126.
5. Nichols WW, Pepine CJ, O'Rourke MF (1999) Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke. N Engl J Med 340:1762-1763.
6. Rothwell PM (2000) Carotid artery disease and the risk of ischaemic stroke and coronary vascular events. Cerebrovasc Dis 10 Suppl 5:21-33.
7. Pasterkamp G, Schoneveld AH, Van Der Wal AC, Haudenschild CC, Clarijs RJ, et al. (1998) Relation of arterial geometry to luminal narrowing and histologic markers for plaque vulnerability: the remodeling paradox. J Am Coll Cardiol 32:655-662.
8. Van De Voorde J, Pauwels B, Boydens C, Decaluwe K (2013) Adipocytokines in relation to cardiovascular disease. Metabolism 62:1513-1521.
9. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, et al. (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432.
10. Mattu HS, Randeva HS (2013) Role of adipokines in cardiovascular disease. J Endocrinol 216:T17-36.
11. Lago F, Dieguez C, Gomez-Reino J, Gualillo O (2007) The emerging role of adipokines as mediators of inflammation and immune responses. Cytokine Growth Factor Rev 18:313-325.
12. Sierra-Johnson J, Romero-Corral A, Lopez-Jimenez F, Gami AS, Sert Kuniyoshi FH, et al. (2007) Relation of increased leptin concentrations to history of myocardial infarction and stroke in the United States population. Am J Cardiol 100:234-239.
13. Rohren EM, Turkington TG, Coleman RE (2004) Clinical applications of PET in oncology. Radiology 231:305-332.
14. Bural GG, Torigian DA, Chamroonrat W, Houseni M, Chen W, et al. (2008) FDG-PET is an effective imaging modality to detect and quantify age-related atherosclerosis in large arteries. Eur J Nucl Med Mol Imaging 35:562-569.
15. Rudd JH, Myers KS, Bansilal S, Machac J, Rafique A, et al. (2007) (18) Fluorodeoxyglucose positron emission tomography imaging of atherosclerotic plaque inflammation is highly reproducible: implications for atherosclerosis therapy trials. J Am Coll Cardiol 50:892-896.
16. 18F-FDG PET/CT. J Nucl Med 45:1816-1821.
17. Zhuang H, Alavi A (2002) 18-fluorodeoxyglucose positron emission tomographic imaging in the detection and monitoring of infection and inflammation. Semin Nucl Med 32:47-59.
18. 18F]-fluorodeoxyglucose positron emission tomography. Circulation 105:2708-2711.
19. 18F-fluorodeoxyglucose positron emission tomography imaging provides a noninvasive measure of carotid plaque inflammation in patients. J Am Coll Cardiol 48:1818-1824.
20. 18F]-fluorodeoxyglucose positron emission tomography is associated with the metabolic syndrome. J Am Coll Cardiol 49:1533-1539.
21. Takamura N, Hayashida N, Hagane K, Kadota K, Yamasaki H, et al. (2010) Leptin to high-molecular-weight adiponectin ratio is independently correlated with carotid intima-media thickness in men, but not in women. Biomarkers 15:340-344.
22. National Kidney F (2002) K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis 39:S1-266.
23. Kamasaki T, Hayashida N, Miyamoto I, Usui T, Chiba K, et al. (2014) PET/CT shows subjective pain in shoulder joints to be associated with uptake of (18) F-FDG. Nucl Med Commun 35:44-50.
24. Minami S, Suga K, Inokuma T, Furukawa M, Chiba K (2007) Detection of lymph node metastasis using PET/CT in cholangiocarcinoma. Acta Med Nagasaki 52:59-61.
25. Chiba K, Isoda M, Chiba M, Kanematsu T, Eguchi S (2010) Significance of PET/CT in determining actual TNM staging for patients with various lung cancer. Int Surg 95:197-204.
26. 18F-FDG uptake to C-reactive protein and Framingham risk score in a large cohort of asymptomatic adults. J Nucl Med 54:2070-2076.
27. 18F-fluorodeoxyglucose positron emission tomography. Int J Cardiol 163:277-281.
28. 18F-FDG PET. J Nucl Med 52:10-17.
29. Roemmich JN, Clark PA, Berr SS, Mai V, Mantzoros CS, et al. (1998) Gender differences in leptin levels during puberty are related to the subcutaneous fat depot and sex steroids. Am J Physiol 275:E543-551.
30. Wannamethee SG, Tchernova J, Whincup P, Lowe GD, Kelly A, et al. (2007) Plasma leptin: associations with metabolic, inflammatory and haemostatic risk factors for cardiovascular disease. Atherosclerosis 191:418-426.
31. Dubey L, Zeng H, Hashmi S, Hongjie W, Tao H (2008) Association of plasma leptin levels and complexity of the culprit lesion in patients with unstable angina. Int J Cardiol 126:183-189.
32. Schneiderman J, Schaefer K, Kolodgie FD, Savion N, Kotev-Emeth S, et al. (2012) Leptin locally synthesized in carotid atherosclerotic plaques could be associated with lesion instability and cerebral emboli. J Am Heart Assoc 1:e001727.
33. Badimon L, Vilahur G (2012) LDL-cholesterol versus HDL-cholesterol in the atherosclerotic plaque: inflammatory resolution versus thrombotic chaos. Ann N Y Acad Sci 1254:18-32.
34. Libby P, Theroux P (2005) Pathophysiology of coronary artery disease. Circulation 111:3481-3488.
35. Ference BA, Mahajan N (2013) The role of early LDL lowering to prevent the onset of atherosclerotic disease. Curr Atheroscler Rep 15:312.
36. Tahara N, Kai H, Ishibashi M, Nakaura H, Kaida H, et al. (2006) Simvastatin attenuates plaque inflammation: evaluation by fluorodeoxyglucose positron emission tomography. J Am Coll Cardiol 48:1825-1831.
37. Montecchi FR, Menzinger G, Lala A (2001) Carotid intima-media thickness in patients with Type 2 diabetes and hypercholesterolemia. Diabetes Nutr Metab 14:58-61.
38. Lindholm H, Brolin F, Jonsson C, Jacobsson H (2013) The relation between the blood glucose level and the FDG uptake of tissues at normal PET examinations. EJNMMI Res 3:50.
39. Lindholm P, Minn H, Leskinen-Kallio S, Bergman J, Ruotsalainen U, et al. (1993) Influence of the blood glucose concentration on FDG uptake in cancer-a PET study. J Nucl Med 34:1-6.