Single domain antibody coated gold nanoparticles as enhancer for Clostridium difficile toxin detection by electrochemical impedance immunosensors

Bioelectrochemistry

Volumn 101, Issue , 2015, Pages 153-158

  Zhu, Zanzan ^a   Shi, Lianfa ^b   Feng, Hanping ^b   Susan Zhou, H ^a  

^a Worcester Polytechnic Institute   (United States)

^b UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

Author keywords

Clostridium difficile toxin detection; Electrochemical impedance immunosensors; Gold nanoparticles; Signal amplification

Indexed keywords

ANTIBODIES; CLOSTRIDIUM; ELECTRODES; ELECTRON TRANSITIONS; GOLD; IMMUNOSENSORS; METAL NANOPARTICLES; NANOPARTICLES; SIGNAL DETECTION; SIGNAL TO NOISE RATIO; TOXIC MATERIALS; TRANSMISSION ELECTRON MICROSCOPY;

AMPLIFICATION EFFECTS; CLOSTRIDIUM DIFFICILE; ELECTROCHEMICAL IMPEDANCE; ELECTRON-TRANSFER RESISTANCE; GOLD NANOPARTICLES; SIGNAL AMPLIFICATIONS; SINGLE-DOMAIN ANTIBODIES; TOXIN DETECTION;

CHEMICAL DETECTION;

ANTITOXIN; CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; GOLD NANOPARTICLE; NANOBODY; BACTERIAL PROTEIN; BACTERIAL TOXIN; ENTEROTOXIN; GOLD; IMMOBILIZED ANTIBODY; NANOPARTICLE; TCDA PROTEIN, CLOSTRIDIUM DIFFICILE; TOXB PROTEIN, CLOSTRIDIUM DIFFICILE;

ARTICLE; BIOSENSOR; CONTROLLED STUDY; ELECTROCHEMICAL ANALYSIS; ELECTROCHEMICAL IMPEDANCE IMMUNOSENSOR; ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY; ELECTRODE; ELECTRON TRANSPORT; IMMUNOASSAY; IMMUNOSENSOR; NONHUMAN; SIGNAL NOISE RATIO; TRANSMISSION ELECTRON MICROSCOPY; CHEMISTRY; DEVICES; EQUIPMENT DESIGN; FECES; GENETIC PROCEDURES; HUMAN; IMMUNOLOGY; IMPEDANCE; LIMIT OF DETECTION; MICROBIOLOGY; PROCEDURES;

ANTIBODIES, IMMOBILIZED; BACTERIAL PROTEINS; BACTERIAL TOXINS; BIOSENSING TECHNIQUES; ELECTRIC IMPEDANCE; ENTEROTOXINS; EQUIPMENT DESIGN; FECES; GOLD; HUMANS; IMMUNOASSAY; LIMIT OF DETECTION; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; SINGLE-DOMAIN ANTIBODIES;

EID: 84910598076     PISSN: 15675394     EISSN: 1878562X     Source Type: Journal    
DOI: 10.1016/j.bioelechem.2014.10.003     Document Type: Article

References (41)

1. Khanna S., Pardi D.S. Clostridium difficile infection: new insights into management. Mayo Clin. 2012, 87:1106-1117.
2. Carter G.P., Rood J.I., Gut Lyras D. The role of toxin A and toxin B in Clostridium difficile-associated disease. Microbes 2010, 1:58-64.
3. Drudy D., Fanning S., Kyne L. Toxin A-negative, toxin B-positive Clostridium difficile. Int. J. Infect. Dis. 2007, 11:5-10.
4. LaMarche M.J., Leeds J.A., Amaral A., Brewer J.T., Bushell S.M., Deng G., Dewhurst J.M., Ding J., Dzink-Fox J., Gamber G., Jain A., Lee K., Lee L., Lister T., McKenney D., Mullin S., Osborne C., Palestrant D., Patane M.A., Rann E.M., Sachdeva M., Shao J., Tiamfook S., Trzasko A., Whitehead L., Yifru A., Yu D., Yan W., Zhu Q.J. Discovery of LFF571: an investigational agent for Clostridium difficile infection. Med. Chem. 2012, 55:2376-2387.
5. Cohen S.H., Gerding D.N., Johnson S., Kelly C.P., Loo V.G., McDonald L.C., Pepin J., Wilcox M.H. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). Infect. Control Hosp. Epidemiol. 2010, 31:431-455.
6. Rodriguez-Palacios A., Borgmann S., Kline T.R., LeJeune J.T. Clostridium difficile in foods and animals: history and measures to reduce exposure. Anim. Health Res. Rev. 2013, 14:11-29.
7. O'Connor D., Hynes P., Cormican M., Collins E., Corbett-Feeney G., Cassidy M. Evaluation of methods for detection of toxins in specimens of feces submitted for diagnosis of Clostridium difficile-associated diarrhea. J. Clin. Microbiol. 2001, 39:2846-2849.
8. Gerding D.N., Johnson S., Peterson L.R., Mulligan M.E., Silva J. Clostridium difficile-associated diarrhea and colitis. Infect. Control Hosp. Epidemiol. 1995, 16:459-477.
9. Chang T.W., Gorbach S.L., Bartlett J.B. Neutralization of Clostridium difficile toxin by Clostridium sordellii antitoxins. Infect. Immun. 1978, 22:418-422.
10. He X., Wang J., Steele J., Sun X., Nie W., Tzipori S., Feng H. An ultrasensitive rapid immunocytotoxicity assay for detecting Clostridium difficile toxins. J. Microbiol. Methods 2009, 78:97-100.
11. Wilkins T.D., Lyerly D.M. Clostridium difficile testing: after 20years, still challenging. J. Clin. Microbiol. 2003, 41:531-534.
12. Yolken R.H., Whitcom L.S., Marien G., Bartlett J.D., Libby J., Ehrich M., Wilkins T. Enzyme immunoassay for the detection of Clostridium difficile antigen. J. Infect. Dis. 1981, 144:378-378.
13. 4/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein. Int. J. Nanomedicine 2011, 6:3259-3269.
14. Grieshaber D., MacKenzie R., Voros J., Reimhult E. Electrochemical biosensors - sensor principles and architectures. Sensors 2008, 8:1400-1458.
15. Suni I.I. Impedance methods for electrochemical sensors using nanomaterials. Trends Anal. Chem. 2008, 27:604-611.
16. Wang Y., Ye Z., Ying Y. New trends in impedimetric biosensors for the detection of foodborne pathogenic bacteria. Sensors 2012, 12:3449-3471.
17. Chang B.Y., Park S.M. Electrochemical impedance spectroscopy. Annu. Rev. Anal. Chem. 2010, 3:207-229.
18. Dominguez-Benetton X., Sevda S., Vanbroekhoven K., Pant D. The accurate use of impedance analysis for the study of microbial electrochemical systems. Chem. Soc. Rev. 2012, 41:7228-7246.
19. Cho E.C., Jang B.O., Kim E.J., Koo K.K. Characterization of a carbon composite electrode for an electrochemical immunosensor. Korean J. Chem. Eng. 2008, 25:548-552.
20. Yang L., Li Y., Erf G.F. Interdigitated array microelectrode-based electrochemical impedance immunosensor for detection of Escherichia coli O157:H7. Anal. Chem. 2004, 76:1107-1113.
21. Chen X., Wang Y., Zhou J., Yan W., Li X., Zhu J.J. Electrochemical impedance immunosensor based on three-dimensionally ordered macroporous gold film. Anal. Chem. 2008, 80:2133-2140.
22. Pei R., Cheng Z., Wang E., Yang X. Amplification of antigen-antibody interactions based on biotin labeled protein-streptavidin network complex using impedance spectroscopy. Biosens. Bioelectron. 2001, 16:355-361.
23. Ruan C., Yang L., Li Y. Immunobiosensor chips for detection of Escherichia coli O157:H7 using electrochemical impedance spectroscopy. Anal. Chem. 2002, 74:4814-4820.
24. Hayat A., Yang C., Rhouati A., Marty J.L. Recent advances and achievements in nanomaterial-based, and structure switchable aptasensing platforms for ochratoxin a detection. Sensors 2013, 13:15187-15208.
25. Wang J. Nanomaterial-based amplified transduction of biomolecular interactions. Small 2005, 1:1036-1043.
26. Rusling J.F., Kumar C.V., Gutkind J.S., Patel V. Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer. Analyst 2010, 135:2496-2511.
27. Xu Y., Cai H., He P.G., Fang Y.Z. Probing DNA hybridization by impedance measurement based on CdS-oligonucleotide nanoconjugates. Electroanalysis 2004, 16:150-155.
28. Yeh Y.C., Creran B., Rotello V.M. Gold nanoparticles: preparation, properties, and applications in bionanotechnology. Nanoscale 2012, 4:1871-1880.
29. Wenger B., Kugelbrey K., Gao H., Sigrist H., Voirin G. Au-labeled antibodies to enhance the sensitivity of a refractometric immunoassay: detection of cocaine. Biosens. Bioelectron. 2012, 34:94-99.
30. Pingarrón J.M., Yáñez-Sedeño P., González-Cortés A. Gold nanoparticle-based electrochemical biosensors. Electrochim. Acta 2008, 53:5848-5866.
31. Tang H., Chen J., Nie L., Kuang Y., Yao S. A label-free electrochemical immunoassay for carcinoembryonic antigen (CEA) based on gold nanoparticles (AuNPs) and nonconductive polymer film. Biosens. Bioelectron. 2007, 22:1061-1067.
32. Bonanni A., Pividori M.I., Campoy S., Barbe J., del Valle M. Impedimetric detection of double-tagged PCR products using novel amplification procedures based on gold nanoparticles and protein G. Analyst 2009, 134:602-608.
33. Chen H., Jiang J.H., Huang Y., Deng T., Li J.S., Shen G.L., Yu R.Q. An electrochemical impedance immunosensor with signal amplification based on Au-colloid labeled antibody complex. Sensors Actuators B Chem. 2006, 117:211-218.
34. Yang Z.Y., Schmidt D., Liu W.L., Li S., Shi L.F., Sheng J.L., Chen K., Yu H., Tremblay J.M., Chen X.H., Piepenbrink K.H., Sundberg E.J., Kelly C.P., Bai G., Shoemaker C.B., Feng H.P. A novel multivalent, single-domain antibody targeting TcdA and TcdB prevents fulminant Clostridium difficile infection in mice. J. Infect. Dis. 2014, 210:964-972.
35. Yang G., Zhou B., Wang J., He X., Sun X., Nie W., Tzipori S., Feng H. Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium. BMC Microbiol. 2008, 8:192.
36. Grabar K.C., Freeman R.G., Hommer M.B., Natan M.J. Preparation and characterization of Au colloid monolayers. Anal. Chem. 1995, 67:735-743.
37. Slot J.W., Geuze H.J. A new method of preparing gold probes for multiple-labeling cytochemistry. Eur. J. Cell Biol. 1985, 38:87-93.
38. Chen Z.P., Peng Z.F., Zhang P., Jin X.F., Jiang J.H., Zhang X.B., Shen G.L., Yu R.Q. A sensitive immunosensor using colloidal gold as electrochemical label. Talanta 2007, 72:1800-1804.
39. Saleh M., Soliman H., Haenen O., El-Matbouli M. Antibody-coated gold nanoparticles immunoassay for direct detection of Aeromonas salmonicida in fish tissues. J. Fish Dis. 2011, 34:845-852.
40. Liu X., Atwater M., Wang J., Huo Q. Extinction coefficient of gold nanoparticles with different sizes and different capping ligands. Colloids Surf. B: Biointerfaces 2007, 58:3-7.
41. Rezaei B., Khayamian T., Majidi N., Rahmani H. Immobilization of specific monoclonal antibody on Au nanoparticles for hGH detection by electrochemical impedance spectroscopy. Biosens. Bioelectron. 2009, 25:395-399.