Type I interferon-mediated immune response against influenza a virus is attenuated in the absence of p53

Biochemical and Biophysical Research Communications

Volumn 454, Issue 1, 2014, Pages 189-195

  Zhu, Zixiang ^a   Yang, Yifan ^a   Wei, Jianchao ^a   Shao, Donghua ^a   Shi, Zixue ^a   Li, Beibei ^a   Liu, Ke ^a   Qiu, Yafeng ^a   Zheng, Haixue ^a   Ma, Zhiyong ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

Author keywords

Antiviral immune response; Influenza A virus; Interferon stimulated genes; p53; Type I interferon

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE 1; ALPHA INTERFERON; GUANYLATE BINDING PROTEIN 1; INTERFERON; INTERFERON REGULATORY FACTOR 5; INTERFERON REGULATORY FACTOR 7; INTERFERON REGULATORY FACTOR 9; INTERFERON STIMULATED GENE 15; INTERFERON STIMULATED GENE 20; MESSENGER RNA; PROTEIN P53; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG; ALPHA2A INTERFERON; ANTIVIRUS AGENT; RECOMBINANT PROTEIN; SMALL INTERFERING RNA;

ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; GENE SILENCING; HUMAN; IMMUNOREGULATION; INFLUENZA A (H1N1); INFLUENZA A (H3N2); INFLUENZA A VIRUS (A/PUERTO RICO/8/1934(H1N1)); INFLUENZA VIRUS A H3N2; INFLUENZA VIRUS A H9N2; NONHUMAN; PROTEIN EXPRESSION; RNA INTERFERENCE; UPREGULATION; VIRUS REPLICATION; ANIMAL; CELL LINE; CHICK EMBRYO; DEFICIENCY; DOG; GENE EXPRESSION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; INFLUENZA VIRUS A; PATHOGENICITY; PHYSIOLOGY; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CHICK EMBRYO; DOGS; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GENES, P53; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLUENZA A VIRUS; INTERFERON TYPE I; INTERFERON-ALPHA; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53; VIRUS REPLICATION;

EID: 84910148691     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.10.067     Document Type: Article

References (29)

1. L. Manzoli, J.P. Ioannidis, M.E. Flacco, et al., Effectiveness and harms of seasonal and pandemic influenza vaccines in children, adults and elderly: a critical review and re-analysis of 15 meta-analyses, Hum. Vaccin. Immunother. 8 (2012) 851-862.
2. A. García-Sastre, Induction and evasion of type I interferon responses by influenza viruses, Virus Res. 162 (2011) 12-18.
3. D.J. Lenschow, C. Lai, N. Frias-Staheli, et al., IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses, Proc. Natl. Acad. Sci. U.S.A. 104 (2007) 1371-1376.
4. L. Espert, G. Degols, C. Gongora, et al., ISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic viruses, J. Biol. Chem. 278 (2003) 16151-16158.
5. Z. Zhu, Z. Shi, W. Yan, et al., Nonstructural protein 1 of influenza A virus interacts with human guanylate-binding protein 1 to antagonize antiviral activity, PLoS ONE 8 (2013) e55920.
6. R. Le Goffic, J. Pothlichet, D. Vitour, et al., Cutting edge: influenza A virus activates TLR3-dependent inflammatory and RIG-I-dependent antiviral responses in human lung epithelial cells, J. Immunol. 178 (2007) 3368-3372.
7. J.Y. Min, R.M. Krug, The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: inhibiting the 2′-5′ oligo (A) synthetase/ RNase L pathway, Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 7100-7105.
8. B. Rao, S. Lain, A.M. Thompson, p53-Based cyclotherapy: exploiting the 'guardian of the genome' to protect normal cells from cytotoxic therapy, Br. J. Cancer 109 (2013) 2954-2958.
9. A. Takaoka, S. Hayakawa, H. Yanai, et al., Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence, Nature 424 (2003) 516-523.
10. O. Laptenko, C. Prives, Transcriptional regulation by p53: one protein, many possibilities, Cell Death Differ. 13 (2006) 951-961.
11. C. Rivas, S.A. Aaronson, C. Munoz-Fontela, Dual role of p53 in innate antiviral immunity, Viruses 2 (2010) 298-313.
12. Z. Zhu, J. Wei, Z. Shi, et al., Identification of human guanylate-binding protein 1 gene (hGBP1) as a direct transcriptional target gene of p53, Biochem. Biophys. Res. Commun. 436 (2013) 204-211.
13. T. Mori, Y. Anazawa, M. Iiizumi, et al., Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53, Oncogene 21 (2002) 2914-2918.
14. M.W. Beilharz, J.M. Cummins, A.L. Bennett, Protection from lethal influenza virus challenge by oral type 1 interferon, Biochem. Biophys. Res. Commun. 355 (2007) 740-744.
15. E. Haasbach, K. Droebner, A.B. Vogel, et al., Low-dose interferon type I treatment is effective against H5N1 and swine-origin H1N1 influenza A viruses in vitro and in vivo, J. Interferon Cytokine Res. 31 (2011) 515-525.
16. E. Turpin, K. Luke, J. Jones, et al., Influenza virus infection increases p53 activity: role of p53 in cell death and viral replication, J. Virol. 79 (2005) 8802-8811.
17. C. Muñoz-Fontela, M. Pazos, I. Delgado, et al., p53 serves as a host antiviral factor that enhances innate and adaptive immune responses to influenza A virus, J. Immunol. 187 (2011) 6428-6436.
18. A.R. Bluyssen, J.E. Durbin, D.E. Levy, ISGF3 gamma p48, a specificity switch for interferon activated transcription factors, Cytokine Growth Factor Rev. 7 (1996) 11-17.
19. C. Muñoz-Fontela, S. Macip, L. Martínez-Sobrido, et al., Transcriptional role of p53 in interferon-mediated antiviral immunity, J. Exp. Med. 205 (2008) 1929-1938.
20. Y. Shen, X. Wang, L. Guo, et al., Influenza A virus induces p53 accumulation in a biphasic pattern, Biochem. Biophys. Res. Commun. 382 (2009) 331-335.
21. X. Wang, X. Deng, W. Yan, et al., Stabilization of p53 in influenza A virus-infected cells is associated with compromised MDM2-mediated ubiquitination of p53, J. Biol. Chem. 287 (2012) 18366-18375.
22. X.X. Sun, Y.G. Wang, D.P. Xirodimas, et al., Perturbation of 60 S ribosomal biogenesis results in ribosomal protein L5- and L11-dependent p53 activation, J. Biol. Chem. 285 (2010) 25812-25821.
23. T. Sareneva, S. Matikainen, M. Kurimoto, et al., Influenza A virus-induced IFNalpha/beta and IL-18 synergistically enhance IFN-gamma gene expression in human T cells, J. Immunol. 160 (1998) 6032-6038.
24. S.Y. Liu, D.J. Sanchez, G. Cheng, New developments in the induction and antiviral effectors of type I interferon, Curr. Opin. Immunol. 23 (2011) 57-64.
25. S. Pestka, A dance between interferon-alpha/beta and p53 demonstrates collaborations in tumor suppression and antiviral activities, Cancer Cell 4 (2003) 85-87.
26. B. Huang, Z.T. Qi, Z. Xu, et al., Global characterization of interferon regulatory factor (IRF) genes in vertebrates: glimpse of the diversification in evolution, BMC Immunol. 11 (2010) 22.
27. K. Honda, H. Yanai, H. Negishi, et al., IRF-7 is the master regulator of type-I interferon-dependent immune responses, Nature 434 (2005) 772-777.
28. R. Alberts, B. Srivastava, H. Wu, et al., Gene expression changes in the host response between resistant and susceptible inbred mouse strains after influenza A infection, Microbes Infect. 12 (2010) 309-318.
29. S.D. Der, A. Zhou, B.R. Williams, et al., Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays, Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 15623-15628.