-
1
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
Motzer RJ, Figlin RA, Hutson TE, et al.: Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007;356:115-24.
-
(2007)
N Engl J Med
, vol.356
, pp. 115-124
-
-
Motzer, R.J.1
Figlin, R.A.2
Hutson, T.E.3
-
2
-
-
77949890945
-
Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
-
Sternberg CN, Davis ID, Mardiak J, et al.: Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol 2010;28:1061-8.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1061-1068
-
-
Sternberg, C.N.1
Davis, I.D.2
Mardiak, J.3
-
3
-
-
37349080670
-
Bevacizumab plus interferon-Alfa2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind phase III trial
-
Escudier B, Pluzanska A, Koralewski P, et al.: Bevacizumab plus interferon-Alfa2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet 2007;370:2103-11.
-
(2007)
Lancet
, vol.370
, pp. 2103-2111
-
-
Escudier, B.1
Pluzanska, A.2
Koralewski, P.3
-
4
-
-
34249779568
-
Temsirolimus, interferon or both for advanced renal cell carcinoma
-
Hudes G, Carducci M, Tomczyk P, et al.: Temsirolimus, interferon, or both for advanced renal cell carcinoma. N Engl J Med 2007;336:2271-81.
-
(2007)
N Engl J Med
, vol.336
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczyk, P.3
-
5
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
Escudier B, Eisen T Stadler WM, et al.: Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 2007;356:125-34.
-
(2007)
N Engl J Med
, vol.356
, pp. 125-134
-
-
Escudier, B.1
Eisen Stadler T, W.M.2
-
6
-
-
79959549917
-
Temsirolimus and bevacizumab, or sunitinib, or interferon alfa and bevacizumab for patients with advanced renal cell carcinoma (TORACA): A randomised phase II trial
-
Négrier S, Gravis G, Pérol D, et al.: Temsirolimus and bevacizumab, or sunitinib, or interferon alfa and bevacizumab for patients with advanced renal cell carcinoma (TORACA): a randomised phase II trial. Lancet Oncol 2011;12:673-80.
-
(2011)
Lancet Oncol
, vol.12
, pp. 673-680
-
-
Négrier, S.1
Gravis, G.2
Pérol, D.3
-
7
-
-
48649107474
-
Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised placebo-controlled phase 3 trial
-
Motzer RJ, Escudier B, Oudard S, et al.: Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised placebo-controlled phase 3 trial. Lancet 2008;372:449-56.
-
(2008)
Lancet
, vol.372
, pp. 449-456
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
-
8
-
-
21044433148
-
Prognostic value of histologic subtypes in renal cell carcinoma: A multicenter experience
-
Patard JJ. Leray E, Rioux-Leclercq N, et al.: Prognostic value of histologic subtypes in renal cell carcinoma: a multicenter experience. J Clin Oncol 2005;23:2763-71.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2763-2771
-
-
Patard, J.J.1
Leray, E.2
Rioux-Leclercq, N.3
Patard, Jj.4
-
9
-
-
0036138580
-
Interferonalfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma
-
Motzer RJ, Bacik J, Murphy B, et al.: Interferonalfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J Clin Oncol 2002;20:289-96.
-
(2002)
J Clin Oncol
, vol.20
, pp. 289-296
-
-
Motzer, R.J.1
Bacik, J.2
Murphy, B.3
-
10
-
-
73349084973
-
Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-Targeted agents: Results from a large, multicenter study
-
Heng DY, Xie W, Regan MM, et al.: Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-Targeted agents: results from a large, multicenter study. J Clin Oncol 2009;27: 5794-9.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5794-5799
-
-
Heng, D.Y.1
Xie, W.2
Regan, M.M.3
-
11
-
-
84892157802
-
Validation of the MSKCC and Heng risk criteria models for predicting survival in patients with metastatic renal cell carcinoma treated with sunitinib
-
Kwon WA, Cho IC, Yu A, et al.: Validation of the MSKCC and Heng risk criteria models for predicting survival in patients with metastatic renal cell carcinoma treated with sunitinib. Ann Surg Oncol 2013;20:4397-404.
-
(2013)
Ann Surg Oncol
, vol.20
, pp. 4397-4404
-
-
Kwon, W.A.1
Cho, I.C.2
Yu, A.3
-
12
-
-
80051699497
-
Prognostic model for survival in patients with metastatic renal cell carcinoma: Results from the International Kidney Cancer Working Group
-
Manola J, Royston P, Elson P, et al.: Prognostic model for survival in patients with metastatic renal cell carcinoma: results from the International Kidney Cancer Working Group. Clin Cancer Res 2011;17:5443-50.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5443-5450
-
-
Manola, J.1
Royston, P.2
Elson, P.3
-
13
-
-
84861735070
-
Treatment selection in metastatic renal cell carcinoma: Expert consensus
-
Escudier B, Szyczylik C, Porta C, et al.: Treatment selection in metastatic renal cell carcinoma: expert consensus. Nat Rev Clin Oncol 2012;9:327-37.
-
(2012)
Nat Rev Clin Oncol
, vol.9
, pp. 327-337
-
-
Escudier, B.1
Szyczylik, C.2
Porta, C.3
-
14
-
-
48749092867
-
Firstline bevacizumab combined with reduced dose interferon alpha2a is active in patients with metastatic renal cell carcinoma
-
Melichar B, Koralewski P, Ravaud A, et al.: Firstline bevacizumab combined with reduced dose interferon alpha2a is active in patients with metastatic renal cell carcinoma. Ann Oncol 2008;8: 1470-76.
-
(2008)
Ann Oncol
, vol.8
, pp. 1470-1476
-
-
Melichar, B.1
Koralewski, P.2
Ravaud, A.3
-
15
-
-
84927941376
-
Bevacizumab (BEV) + low-dose interferon 2a (IFN) for first-line treatment of metastatic renal cell carcinoma (mRCC): Final safety and efficacy data from the prospective BEVLiN study
-
abstr 809P
-
Melichar B. Bevacizumab (BEV) + low-dose interferon 2a (IFN) for first-line treatment of metastatic renal cell carcinoma (mRCC): final safety and efficacy data from the prospective BEVLiN study. ESMO 2012;abstr 809P.
-
ESMO 2012
-
-
Melichar, B.1
-
17
-
-
84872281935
-
Randomized, open-label, phase III trial of pazopanib versus sunitinib in first-line treatment of patients with metastatic renal-cell carcinoma (mRCC): Results of the COMPARZ trial
-
abstr LBA8
-
Motzer RJ, Hudson TE, Reeves J, et al.: Randomized, open-label, phase III trial of pazopanib versus sunitinib in first-line treatment of patients with metastatic renal-cell carcinoma (mRCC): results of the COMPARZ trial. ESMO 2012;abstr LBA8.
-
ESMO 2012
-
-
Motzer, R.J.1
Hudson, T.E.2
Reeves, J.3
-
18
-
-
62449186539
-
Randomized phase II trial of first-line treatment of sorafenib versus interferon alfa-2a in patients with metastatic renal cell carcinoma
-
Escudier B, Szcylik C, Hutson TE, et al.: Randomized phase II trial of first-line treatment of sorafenib versus interferon alfa-2a in patients with metastatic renal cell carcinoma. J Clin Oncol 2009; 27:1280-9.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1280-1289
-
-
Escudier, B.1
Szcylik, C.2
Hutson, T.E.3
-
19
-
-
74549209552
-
Upfront, randomized, phase 2 trial of sorafenib versus sorafenib and low-dose interferon alfa in patients with advanced renal cell carcinoma: Clinical and biomarker analysis
-
Jonasch E, Corn P, Pagliaro LC, et al.: Upfront, randomized, phase 2 trial of sorafenib versus sorafenib and low-dose interferon alfa in patients with advanced renal cell carcinoma: clinical and biomarker analysis. Cancer 2010;116:57-65.
-
(2010)
Cancer
, vol.116
, pp. 57-65
-
-
Jonasch, E.1
Corn, P.2
Pagliaro, L.C.3
-
20
-
-
79954438593
-
Sorafenib with interleukin-2 vs. Sorafenib alone in metastatic renal cell carcinoma: The ROSORC trial
-
Procopio G, Verzoni E, Bracarda S, et al.: Sorafenib with interleukin-2 vs. sorafenib alone in metastatic renal cell carcinoma: the ROSORC trial. Br J Cancer 2011;104:1256-61.
-
(2011)
Br J Cancer
, vol.104
, pp. 1256-1261
-
-
Procopio, G.1
Verzoni, E.2
Bracarda, S.3
-
21
-
-
80255135379
-
AMG 386 in combination with sorafenib in patients (pts) with metastatic renal cell cancer (mRCC): A randomized, double-blind, placebo-controlled, phase II trial
-
abstr 309
-
Rini B, Wilding G, Hudes G, et al.: AMG 386 in combination with sorafenib in patients (pts) with metastatic renal cell cancer (mRCC): a randomized, double-blind, placebo-controlled, phase II trial. J Clin Oncol 2011:29(suppl 7):abstr 309.
-
(2011)
J Clin Oncol
, vol.29
-
-
Rini, B.1
Wilding, G.2
Hudes, G.3
-
22
-
-
84884155299
-
Temsirolimus vs sorafenib as second-line therapy in metastatuic renal cell carcinoma: Results from the INTORSECT trial
-
abstr LBA22
-
Hutson T, Escudier B, Esteban E, et al.: Temsirolimus vs sorafenib as second-line therapy in metastatuic renal cell carcinoma: results from the INTORSECT trial. ESMO 2012;abstr LBA22.
-
(2012)
ESMO
-
-
Hutson, T.1
Escudier, B.2
Esteban, E.3
-
23
-
-
84879526008
-
Record-3: Phase II randomized trial comparing sequential first-line everolimus (EVE) and second-line sunitinib (SUN) versus first-line SUN and second-line EVE in patients with metastatic renal cell carcinoma (mRCC)
-
Beilage 1 31.
-
Motzer JR, Barrios CH, Kim TM, Falcon S, Cosgriff T, et al.: Record-3: phase II randomized trial comparing sequential first-line everolimus (EVE) and second-line sunitinib (SUN) versus first-line SUN and second-line EVE in patients with metastatic renal cell carcinoma (mRCC). J Clin Oncol 2013;Beilage 1 31. 15.
-
(2013)
J Clin Oncol
, pp. 15
-
-
Motzer, J.R.1
Barrios, C.H.2
Kim, T.M.3
Falcon, S.4
Cosgriff, T.5
-
24
-
-
82755183572
-
Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial
-
Rini BI, Escudier B, Tomczak P, et al.: Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial. Lancet 2011;378:1931-9.
-
(2011)
Lancet
, vol.378
, pp. 1931-1939
-
-
Rini, B.I.1
Escudier, B.2
Tomczak, P.3
-
25
-
-
79955728914
-
Randomized phase II multicenter study of the efficacy and safety of sunitinib on the 4/2 versus continuous dosing schedule as first-line therapy of metastatic renal carcinoma: Renal EFFECT trial
-
abstr LBA 308
-
Motzer RJ, Hutson TE, Olsen MR, et al.: Randomized phase II multicenter study of the efficacy and safety of sunitinib on the 4/2 versus continuous dosing schedule as first-line therapy of metastatic renal carcinoma: renal EFFECT trial. J Clin Oncol 2011;29(suppl 7):abstr LBA 308.
-
(2011)
J Clin Oncol
, vol.29
-
-
Motzer, R.J.1
Hutson, T.E.2
Olsen, M.R.3
-
26
-
-
77952318310
-
Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: Final results of CALGB 90206
-
Rini BI, Halabi S, Rosenberg JE, et al.: Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206. J Clin Oncol 2010;28:2137-43.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2137-2143
-
-
Rini, B.I.1
Halabi, S.2
Rosenberg, J.E.3
|