Inhibition of stearoyl-CoA desaturase-1 in differentiating 3T3-L1 preadipocytes upregulates elongase 6 and downregulates genes affecting triacylglycerol synthesis

International Journal of Obesity

Volumn 38, Issue 11, 2014, Pages 1449-1456

  Ralston, J C ^a   Badoud, F ^a   Cattrysse, B ^a   McNicholas, P D ^a   Mutch, D M ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

Clustering; Fatty acids; Gas chromatography; Lipid metabolism; Microarray

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ACYL COENZYME A DESATURASE 1; DIACYLGLYCEROL ACYLTRANSFERASE 2; ELONGASE 6; FATTY ACID; GLUCOKINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ACYL COENZYME A DESATURASE; ACYLTRANSFERASE; FATTY ACID ELONGASES; MONOUNSATURATED FATTY ACID; PALMITOLEIC ACID; SCD1 PROTEIN, MOUSE;

3T3 CELL LINE; ADIPOGENESIS; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; GAS CHROMATOGRAPHY; GENE EXPRESSION; LIPID METABOLISM; LIPOGENESIS; MICROARRAY ANALYSIS; MOUSE; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PROADIPOCYTE; PROTEIN CONTENT; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING; ADIPOCYTE; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL CULTURE; ENZYMOLOGY; GENE EXPRESSION REGULATION; METABOLISM; TISSUE MICROARRAY;

3T3-L1 CELLS; ACETYLTRANSFERASES; ADIPOCYTES; ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELLS, CULTURED; CHROMATOGRAPHY, GAS; DOWN-REGULATION; FATTY ACIDS; FATTY ACIDS, MONOUNSATURATED; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MICE; STEAROYL-COA DESATURASE; TISSUE ARRAY ANALYSIS; TRIGLYCERIDES; UP-REGULATION;

EID: 84910131773     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2014.35     Document Type: Article

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