Vitamin D receptor ApaI a allele is associated with better childhood asthma control and improvement in ability for daily activities

OMICS A Journal of Integrative Biology

Volumn 18, Issue 11, 2014, Pages 673-681

  Iordanidou, Maria ^a   Paraskakis, Emmanouil ^b   Giannakopoulou, Efstathia ^a   Tavridou, Anna ^a,c   Gentile, Giovanna ^d   Borro, Marina ^e   Simmaco, Maurizio ^d,e   Chatzimichael, Athanasios ^b   Bush, Andrew ^f   Manolopoulos, Vangelis G ^a,c  

^a DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

^b Department of Paediatrics ^*  (United States)

^c Academic General Hospital of Evros   (Greece)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

^f ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; APAI GENE; ARTICLE; ASTHMA; BSMI GENE; CHILD; CHILDHOOD ASTHMA CONTROL TEST SCORE; CONTROLLED STUDY; DAILY LIFE ACTIVITY; FEMALE; FOKI GENE; GENE; GENETIC ASSOCIATION; GENOTYPE; GLOBAL INITIATIVE FOR ASTHMA GUIDELINE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRACTICE GUIDELINE; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; TAQI GENE; CASE CONTROL STUDY; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; METABOLISM; PRESCHOOL CHILD;

CALCITRIOL RECEPTOR; VDR PROTEIN, HUMAN; VITAMIN D;

ACTIVITIES OF DAILY LIVING; ASTHMA; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; POLYMORPHISM, GENETIC; RECEPTORS, CALCITRIOL; VITAMIN D;

EID: 84910123804     PISSN: 15362310     EISSN: 15578100     Source Type: Journal    
DOI: 10.1089/omi.2014.0023     Document Type: Article

References (39)

1. Abd El Gawad SS, Abdul Samee ER, Metwali AA, and Abd El Gawad MS. (2012). Vitamin D receptor gene polymorphism and its association with 1,25-dihydroxyvitamin D(3) in patients with Graves disease in an Egyptian population: A pilot study. Endocr Pract 18, 132-139.
2. Adams JS, and Hewison M. (2008). Unexpected actions of vitamin D: New perspectives on the regulation of innate and adaptive immunity. Nat Clin Pract Endocrinol Metab 4, 80-90.
3. Barrett JC, Fry B, Maller J, and Daly MJ. (2005). Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21, 263-265.
4. Bateman ED, Hurd SS, Barnes PJ, et al. (2008). Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 31, 143-178.
5. Bosse Y, Lemire M, Poon AH, et al. (2009). Asthma and genes encoding components of the vitamin D pathway. Respir Res 10, 98.
6. Brehm JM, Celedon JC, Soto-Quiros ME, et al. (2009). Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica. Am J Respir Crit Care Med 179, 765-771.
7. Bush A, and Saglani S. (2010). Management of severe asthma in children. Lancet 376, 814-825.
8. Chinellato I, Piazza M, Sandri M, Peroni D, Piacentini G, and Boner AL. (2011). Vitamin D serum levels and markers of asthma control in Italian children. J Pediatr 158, 437-441.
9. Daley D, Lemire M, Akhabir L, et al. (2009). Analyses of associations with asthma in four asthma population samples from Canada and Australia. Hum Genet 125, 445-459.
10. Ehlayel MS, Bener A, and Sabbah A. (2011). Is high prevalence of vitamin D deficiency evidence for asthma and allergy risks? Eur Ann Allergy Clin Immunol 43, 81-88.
11. Erkocoglu M, Akan A, Civelek E, Kan R, Azkur D, and Kocabas CN. (2012). Consistency of GINA criteria and childhood asthma control test on the determination of asthma control. Pediatr Allergy Immunol 23, 34-39.
12. Fang WL, Gao LB, Liang WB, et al. (2009). Association analysis of vitamin D receptor gene polymorphisms in chinese population with asthma. Iran J Allergy Asthma Immunol 8, 141-147.
13. Fukazawa T, Yabe I, Kikuchi S, et al. (1999). Association of vitamin D receptor gene polymorphism with multiple sclerosis in Japanese. J Neurol Sci 166, 47-52.
14. Ginde AA, Mansbach JM, and Camargo CA Jr. (2009). Vitamin D, respiratory infections, and asthma. Curr Allergy Asthma Rep 9, 81-87.
15. Gupta A, Sjoukes A, Richards D, et al. (2011). Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma. Am J Respir Crit Care Med 184, 1342-1349.
16. Hansdottir S, Monick MM, Lovan N, Powers L, Gerke A, and Hunninghake GW. (2010). Vitamin D decreases respiratory syncytial virus induction of NF-kappaB-linked chemokines and cytokines in airway epithelium while maintaining the antiviral state. J Immunol 184, 965-974.
17. Ismail MF, Elnady HG, and Fouda EM. (2013). Genetic variants in vitamin D pathway in Egyptian asthmatic children: A pilot study. Hum Immunol 74, 1659-1664.
18. Joint Task Force on Practice Parameters, American Academy of Allergy, Asthma and Immunology, American College of Allergy, Asthma, and Immunology, and Joint Council of Allergy, Asthma and Immunology. (2005). Attaining optimal asthma control: a practice parameter. J Allergy Clin Immunol 116, S3-S11.
19. Juniper EF, Wisniewski ME, Cox FM, Emmett AH, Nielsen KE, and O'Byrne PM. (2004). Relationship between quality of life and clinical status in asthma: A factor analysis. Eur Respir J 23, 287-291.
20. Liu AH, Zeiger R, Sorkness C, et al. (2007). Development and cross-sectional validation of the Childhood Asthma Control Test. J Allergy Clin Immunol 119, 817-825.
21. Maalmi H, Sassi FH, Berraies A, Ammar J, Hamzaoui K, and Hamzaoui A. (2013). Association of vitamin D receptor gene polymorphisms with susceptibility to asthma in Tunisian children: A case control study. Hum Immunol 74, 234-240.
22. Melosini L, Dente FL, Bacci E, et al. (2012). Asthma control test (ACT): Comparison with clinical, functional, and biological markers of asthma control. J Asthma 49, 317-323.
23. Monticielo OA, Brenol JC, Chies JA, et al. (2012). The role of BsmI and FokI vitamin D receptor gene polymorphisms and serum 25-hydroxyvitamin D in Brazilian patients with systemic lupus erythematosus. Lupus 21, 43-52.
24. Pani MA, Knapp M, Donner H, et al. (2000). Vitamin D receptor allele combinations influence genetic susceptibility to type 1 diabetes in Germans. Diabetes 49, 504-507.
25. Pillai DK, Iqbal SF, Benton AS, et al. (2011). Associations between genetic variants in vitamin D metabolism and asthma characteristics in young African Americans: A pilot study. J Investig Med 59, 938-946.
26. Poon AH, Laprise C, Lemire M, et al. (2004). Association of vitamin D receptor genetic variants with susceptibility to asthma and atopy. Am J Respir Crit Care Med 170, 967-973.
27. Raby BA, Lazarus R, Silverman EK, et al. (2004). Association of vitamin D receptor gene polymorphisms with childhood and adult asthma. Am J Respir Crit Care Med 170, 1057-1065.
28. Rehan VK, Torday JS, Peleg S, et al. (2002). 1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha, 25-dihydroxy vitamin D3: Production and biological activity studies in pulmonary alveolar type II cells. Mol Genet Metab 76, 46-56.
29. Saadi A, Gao G, Li H, Wei C, Gong Y, and Liu Q. (2009). Association study between vitamin D receptor gene polymorphisms and asthma in the Chinese Han population: A case-control study. BMC Med Genet 10, 71.
30. Sandhu MS, and Casale TB. (2010). The role of vitamin D in asthma. Ann Allergy Asthma Immunol 105, 191-199.
31. Shanker J, Maitra A, Arvind P, et al. (2011). Role of vitamin D levels and vitamin D receptor polymorphisms in relation to coronary artery disease: The Indian atherosclerosis research study. Coron Artery Dis 22, 324-332.
32. Thomas M, Kay S, Pike J, et al. (2009). The Asthma Control Test (ACT) as a predictor of GINA guideline-defined asthma control: Analysis of a multinational cross-sectional survey. Prim Care Respir J 18, 41-49.
33. Uitterlinden AG, Fang Y, Van Meurs JB, Pols HA, and Van Leeuwen JP. (2004). Genetics and biology of vitamin D receptor polymorphisms. Gene 338, 143-156.
34. Velayoudom-Cephise FL, Larifla L, Donnet JP, et al. (2011). Vitamin D deficiency, vitamin D receptor gene polymorphisms and cardiovascular risk factors in Caribbean patients with type 2 diabetes. Diabetes Metab 37, 540-545.
35. Wechsler ME. (2009). Managing asthma in primary care: Putting new guideline recommendations into context. Mayo Clin Proc 84, 707-717.
36. Whitfield GK, Remus LS, Jurutka PW, et al. (2001). Functionally relevant polymorphisms in the human nuclear vitamin D receptor gene. Mol Cell Endocrinol 177, 145-159.
37. Whitley E, and Ball J. (2002). Statistics review 4: Sample size calculations. Crit Care 6, 335-341.
38. Wjst M. (2005). Variants in the vitamin D receptor gene and asthma. BMC Genet 6, 2.
39. Wjst M, Altmüller J, Faus-Kessler T, Braig C, Bahnweg M, and André E (2006). Asthma families show transmission disequilibrium of gene variants in the vitamin D metabolism and signalling pathway. Respir Res 7, 60.