Janus particles as artificial antigen-presenting cells for T cell activation

ACS Applied Materials and Interfaces

Volumn 6, Issue 21, 2014, Pages 18435-18439

  Chen, Bo ^a   Jia, Yilong ^a   Gao, Yuan ^a   Sanchez, Lucero ^a   Anthony, Stephen M ^a,b   Yu, Yan ^a  

^a INDIANA UNIVERSITY   (United States)

^b SANDIA NATIONAL LABORATORIES   (United States)

Author keywords

artificial antigen presenting cells; immunological synapse; Janus particles; ligand pattern; multifunctionality; T cell activation

Indexed keywords

ANTIGENS; BIOACTIVITY; CHEMICAL ACTIVATION; CYTOLOGY; LIGANDS; PROTEINS; SPATIAL DISTRIBUTION;

ARTIFICIAL ANTIGEN; IMMUNOLOGICAL SYNAPSE; JANUS PARTICLES; MULTIFUNCTIONALITY; T CELL ACTIVATION;

T-CELLS;

BIOMATERIAL; CALCIUM;

ANTIGEN PRESENTING CELL; ARTIFICIAL CELL; BIOLOGICAL MODEL; BIOTECHNOLOGY; CHEMISTRY; DRUG EFFECTS; HUMAN; IMMUNOLOGICAL SYNAPSE; IMMUNOLOGY; INTRACELLULAR SPACE; JURKAT CELL LINE; LYMPHOCYTE ACTIVATION; METABOLISM; T LYMPHOCYTE;

ANTIGEN-PRESENTING CELLS; ARTIFICIAL CELLS; BIOCOMPATIBLE MATERIALS; BIOTECHNOLOGY; CALCIUM; HUMANS; IMMUNOLOGICAL SYNAPSES; INTRACELLULAR SPACE; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MODELS, IMMUNOLOGICAL; T-LYMPHOCYTES;

EID: 84910121638     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/am505510m     Document Type: Article

References (30)

1. Hwang, S.; Lahann, J. Differentially Degradable Janus Particles for Controlled Release Applications Macromol. Rapid Commun. 2012, 33, 1178-1183
2. Rahmani, S.; Park, T.-H.; Dishman, A. F.; Lahann, J. Multimodal Delivery of Irinotecan from Microparticles with Two Distinct Compartments J. Controlled Release 2013, 172, 239-245
3. Misra, A. C.; Bhaskar, S.; Clay, N.; Lahann, J. Multicompartmental Particles for Combined Imaging and siRNA Delivery Adv. Mater. 2012, 24, 3850-3856
4. Pregibon, D. C.; Toner, M.; Doyle, P. S. Multifunctional Encoded Particles for High-Throughput Biomolecule Analysis Science 2007, 315, 1393-1396
5. Bong, K. W.; Chapin, S. C.; Doyle, P. S. Magnetic Barcoded Hydrogel Microparticles for Multiplexed Detection Langmuir 2010, 26, 8008-8014
6. Hu, S.-H.; Gao, X. Nanocomposites with Spatially Separated Functionalities for Combined Imaging and Magnetolytic Therapy J. Am. Chem. Soc. 2010, 132, 7234-7237
7. 4-Ag Heterodimer Nanoparticles for Two-Photon Fluorescence Imaging and Magnetic Manipulation Adv. Mater. 2008, 20, 4403-4407
8. Wu, L. Y.; Ross, B. M.; Hong, S.; Lee, L. P. Bioinspired Nanocorals with Decoupled Cellular Targeting and Sensing Functionality Small 2010, 6, 503-507
9. Mescher, M. F. Surface Contact Requirements for Activation of Cytotoxic T Lymphocytes J. Immunol. 1992, 149, 2402-2405
10. Sunshine, J. C.; Perica, K.; Schneck, J. P.; Green, J. J. Particle shape dependence of CD8+ T cell activation by artificial antigen presenting cells Biomaterials 2014, 35, 269-277
11. Fadel, T. R.; Look, M.; Staffier, P. A.; Haller, G. L.; Pfefferle, L. D.; Fahmy, T. M. Clustering of Stimuli on Single-Walled Carbon Nanotube Bundles Enhances Cellular Activation Langmuir 2009, 26, 5645-5654
12. Mandal, S.; Eksteen-Akeroyd, Z. H.; Jacobs, M. J.; Hammink, R.; Koepf, M.; Lambeck, A. J. A.; van Hest, J. C. M.; Wilson, C. J.; Blank, K.; Figdor, C. G.; Rowan, A. E. Therapeutic Nanoworms: Towards Novel Synthetic Dendritic Cells for Immunotherapy Chem. Sci. 2013, 4, 4168-4174
13. Kim, J. V.; Latouche, J.-B.; Riviere, I.; Sadelain, M. The ABCs of Artificial Antigen Presentation Nat. Biotechnol. 2004, 22, 403-410
14. Grakoui, A.; Bromley, S. K.; Sumen, C.; Davis, M. M.; Shaw, A. S.; Allen, P. M.; Dustin, M. L. The Immunological Synapse: A Molecular Machine Controlling T Cell Activation Science 1999, 285, 221-227
15. Lee, K.-H.; Holdorf, A. D.; Dustin, M. L.; Chan, A. C.; Allen, P. M.; Shaw, A. S. T Cell Receptor Signaling Precedes Immunological Synapse Formation Science 2002, 295, 1539-1542
16. Mossman, K. D.; Campi, G.; Groves, J. T.; Dustin, M. L. Altered TCR Signaling from Geometrically Repatterned Immunological Synapses Science 2005, 310, 1191-1193
17. Doh, J.; Irvine, D. J. Immunological synapse arrays: Patterned protein surfaces that modulate immunological synapse structure formation in T cells Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 5700-5705
18. Shen, K.; Thomas, V. K.; Dustin, M. L.; Kam, L. C. Micropatterning of costimulatory ligands enhances CD4+ T cell function Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 7791-7796
19. Deeg, J.; Axmann, M.; Matic, J.; Liapis, A.; Depoil, D.; Afrose, J.; Curado, S.; Dustin, M. L.; Spatz, J. P. T Cell Activation is Determined by the Number of Presented Antigens Nano Lett. 2013, 13, 5619-5626
20. Matic, J.; Deeg, J.; Scheffold, A.; Goldstein, I.; Spatz, J. P. Fine Tuning and Efficient T Cell Activation with Stimulatory aCD3 Nanoarrays Nano Lett. 2013, 13, 5090-5097
21. Delcassian, D.; Depoil, D.; Rudnicka, D.; Liu, M.; Davis, D. M.; Dustin, M. L.; Dunlop, I. E. Nanoscale Ligand Spacing Influences Receptor Triggering in T Cells and NK Cells Nano Lett. 2013, 13, 5608-5614
22. Lewis, R. S. Calcium Signaling Mechanisms in T Lymphocytes Annu. Rev. Immunol. 2001, 19, 497-521
23. Feske, S. Calcium Signalling in Lymphocyte Activation and Disease Nat. Rev. Immunol. 2007, 7, 690-702
24. Manz, B. N.; Jackson, B. L.; Petit, R. S.; Dustin, M. L.; Groves, J. T-Cell Triggering Thresholds are Modulated by the Number of Antigen within Individual T-Cell Receptor Clusters Proc. Natl. Acad. Sci. U.S.A. 2011, 108, 9089-9094
25. Yu, Y.; Fay, N. C.; Smoligovets, A. A.; Wu, H.-J.; Groves, J. T. Myosin IIA Modulates T Cell Receptor Transport and CasL Phosphorylation during Early Immunological Synapse Formation PLoS One 2012, 7, e30704
26. Salles, A.; Billaudeau, C.; Sergé, A.; Bernard, A.-M.; Phélipot, M.-C.; Bertaux, N.; Fallet, M.; Grenot, P.; Marguet, D.; He, H.-T.; Hamon, Y. Barcoding T Cell Calcium Response Diversity with Methods for Automated and Accurate Analysis of Cell Signals (MAAACS) PLoS Comput. Biol. 2013, 9, e1003245
27. Yu, Y.; Smoligovets, A. A.; Groves, J. T. Modulation of T cell signaling by the actin cytoskeleton J. Cell Sci. 2013, 126, 1049-1058
28. Yokosuka, T.; Kobayashi, W.; Sakata-Sogawa, K.; Takamatsu, M.; Hashimoto-Tane, A.; Dustin, M. L.; Tokunaga, M.; Saito, T. Spatiotemporal Regulation of T Cell Costimulation by TCR-CD28 Microclusters and Protein Kinase C θ Translocation Immunity 2008, 29, 589-601
29. Lee, K.-H.; Dinner, A. R.; Tu, C.; Campi, G.; Raychaudhuri, S.; Varma, R.; Sims, T. N.; Burack, W. R.; Wu, H.; Wang, J.; Kanagawa, O.; Markiewicz, M.; Allen, P. M.; Dustin, M. L.; Chakraborty, A. K.; Shaw, A. S. The Immunological Synapse Balances T Cell Receptor Signaling and Degradation Science 2003, 302, 1218-1222
30. Hogg, N.; Laschinger, M.; Giles, K.; McDowall, A. T-cell integrins: more than just sticking points J. Cell Sci. 2003, 116, 4695-4705