The science of cocoa flavanols: Bioavailability, emerging evidence, and proposed mechanisms

Advances in Nutrition

Volumn 5, Issue 5, 2014, Pages 547-549

  Blumberg, Jeffrey B ^a   Ding, Eric L ^b   Dixon, Richard ^c   Pasinetti, Giulio Maria ^d,e   Villarreal, Francisco ^f  

^a TUFTS UNIVERSITY   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF NORTH TEXAS   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOTONIC AGENT; FLAVONE DERIVATIVE; PLANT EXTRACT;

BIOAVAILABILITY; CACAO; CARDIOVASCULAR DISEASES; CHEMISTRY; DRUG EFFECTS; HUMAN; METABOLISM; MITOCHONDRION; NEURODEGENERATIVE DISEASES; ORGANIZATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); RISK FACTOR;

BIOLOGICAL AVAILABILITY; CACAO; CARDIOTONIC AGENTS; CARDIOVASCULAR DISEASES; CONGRESSES AS TOPIC; FLAVONES; HUMANS; MITOCHONDRIA; NEURODEGENERATIVE DISEASES; PLANT EXTRACTS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK FACTORS;

EID: 84910121116     PISSN: 21618313     EISSN: 21565376     Source Type: Journal    
DOI: 10.3945/an.114.006478     Document Type: Conference Paper

References (6)

1. Dixon RA, Liu C, Jun JH. Metabolic engineering of anthocyanins and condensed tannins in plants. Curr Opin Biotechnol 2013;24:329-35.
2. Wang J, Varghese M, Ono K, Yamada M, Levine S, Tzavaras N, Gong B, Hurst WJ, Blitzer RD, Pasinetti GM. Cocoa extracts reduce oligomerization of amyloid-beta: implications for cognitive improvement in Alzheimer's disease. J Alzheimers Dis 2014;41:643-50.
3. Shrime MG, Bauer SR, McDonald AC, Chowdhury NH, Coltart CEM, Ding EL. Flavonoid-rich cocoa consumption affects multiple cardiovascular risk factors in a meta-analysis of short-term studies. J Nutr 2011;141:1982-8.
4. Buitrago-Lopez A, Sanderson J, Johnson L, Warnakula S, Wood A, Di Angelantonio E, Franco OH. Chocolate consumption and cardiometabolic disorders: systematic review and meta-analysis. BMJ 2011;343:d4488.
5. Larsson SC, Virtamo J,Wolk A. Chocolate consumption and risk of stroke: a prospective cohort of men and meta-analysis. Neurology 2012;79:1223-9.
6. Yamazaki KG, Andreyev A, Ortiz-Vilchis P, Petrosyan S, Divakaruni A, Wiley S, De La Fuente C, Perkins G, Ceballos G, Villarreal F, et al. Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function. Int J Cardiol 2014; doi:10.1016/j.ijcard.2014.05.009 [Epub ahead of print].