메뉴 건너뛰기




Volumn 20, Issue 21, 2014, Pages 5343-5345

Hormone whodunit: Clues for solving the case of intratumor androgen production

Author keywords

[No Author keywords available]

Indexed keywords

ABIRATERONE ACETATE; ANDROGEN; ANDROGEN RECEPTOR; ANDROGEN RECEPTOR ANTAGONIST; ANDROSTANOLONE; ANDROSTENEDIONE; PLACEBO; PROSTATE SPECIFIC ANTIGEN; TESTOSTERONE;

EID: 84910093402     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-14-1188     Document Type: Article
Times cited : (3)

References (13)
  • 1
    • 84907393368 scopus 로고    scopus 로고
    • Canonical androstenedione reduction is the predominant source of signaling androgens in hormone-refractory prostate cancer
    • Frankhauser M, Tan Y, Macintyre G, Haviv I, Hong MKH, Nguyen A, et al. Canonical androstenedione reduction is the predominant source of signaling androgens in hormone-refractory prostate cancer. Clin Cancer Res 2014;20:5547-57.
    • (2014) Clin Cancer Res , vol.20 , pp. 5547-5557
    • Frankhauser, M.1    Tan, Y.2    Macintyre, G.3    Haviv, I.4    Hong, M.K.H.5    Nguyen, A.6
  • 2
    • 84890259591 scopus 로고    scopus 로고
    • Molecular pathology and prostate cancer therapeutics: From biology to bedside
    • Rodrigues DN, Butler LM, Estelles DL, de Bono JS. Molecular pathology and prostate cancer therapeutics: from biology to bedside. J Pathol 2014;232:178-84.
    • (2014) J Pathol , vol.232 , pp. 178-184
    • Rodrigues, D.N.1    Butler, L.M.2    Estelles, D.L.3    De Bono, J.S.4
  • 3
    • 79956103537 scopus 로고    scopus 로고
    • Outsmarting androgen receptor: Creative approaches for targeting aberrant androgen signaling in advanced prostate cancer
    • Knudsen KE, Kelly WK. Outsmarting androgen receptor: creative approaches for targeting aberrant androgen signaling in advanced prostate cancer. Expert Rev Endocrinol Metab 2011;6:483-93.
    • (2011) Expert Rev Endocrinol Metab , vol.6 , pp. 483-493
    • Knudsen, K.E.1    Kelly, W.K.2
  • 4
    • 84900373381 scopus 로고    scopus 로고
    • Targeting the androgen receptor pathway in castration-resistant prostate cancer: Progresses and prospects
    • May 19. [Epub ahead of print]
    • Ferraldeschi R, Welti J, Luo J, Attard G, de Bono JS. Targeting the androgen receptor pathway in castration-resistant prostate cancer: progresses and prospects. Oncogene 2014 May 19. [Epub ahead of print].
    • (2014) Oncogene
    • Ferraldeschi, R.1    Welti, J.2    Luo, J.3    Attard, G.4    De Bono, J.S.5
  • 5
    • 77952554163 scopus 로고    scopus 로고
    • Partners in crime: Deregulation of AR activity and androgen synthesis in prostate cancer
    • Knudsen KE, Penning TM. Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer. Trends Endocrinol Metab 2010;21:315-24.
    • (2010) Trends Endocrinol Metab , vol.21 , pp. 315-324
    • Knudsen, K.E.1    Penning, T.M.2
  • 6
    • 84910013455 scopus 로고    scopus 로고
    • Androgen metabolism in prostate cancer: From molecular mechanisms to clinical consequences
    • Chang KH, Ercole CE, Sharifi N. Androgen metabolism in prostate cancer: from molecular mechanisms to clinical consequences. Br J Cancer 2014;111:1249-54.
    • (2014) Br J Cancer , vol.111 , pp. 1249-1254
    • Chang, K.H.1    Ercole, C.E.2    Sharifi, N.3
  • 7
    • 33645056171 scopus 로고    scopus 로고
    • Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
    • Stanbrough M, Bubley GJ, Ross K, Golub TR, Rubin MA, Penning TM, et al. Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer Res 2006;66:2815-25.
    • (2006) Cancer Res , vol.66 , pp. 2815-2825
    • Stanbrough, M.1    Bubley, G.J.2    Ross, K.3    Golub, T.R.4    Rubin, M.A.5    Penning, T.M.6
  • 8
    • 49249119358 scopus 로고    scopus 로고
    • Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth
    • Montgomery RB, Mostaghel EA, Vessella R, Hess DL, Kalhorn TF, Higano CS, et al. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res 2008;68:4447-54.
    • (2008) Cancer Res , vol.68 , pp. 4447-4454
    • Montgomery, R.B.1    Mostaghel, E.A.2    Vessella, R.3    Hess, D.L.4    Kalhorn, T.F.5    Higano, C.S.6
  • 9
    • 34250331066 scopus 로고    scopus 로고
    • Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: Therapeutic implications for castration-resistant prostate cancer
    • Mostaghel EA, Page ST, Lin DW, Fazli L, Coleman IM, True LD, et al. Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer. Cancer Res 2007;67:5033-41.
    • (2007) Cancer Res , vol.67 , pp. 5033-5041
    • Mostaghel, E.A.1    Page, S.T.2    Lin, D.W.3    Fazli, L.4    Coleman, I.M.5    True, L.D.6
  • 10
    • 51049098138 scopus 로고    scopus 로고
    • Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
    • Locke JA, Guns ES, Lubik AA, Adomat HH, Hendy SC, Wood CA, et al. Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer Res 2008;68:6407-15.
    • (2008) Cancer Res , vol.68 , pp. 6407-6415
    • Locke, J.A.1    Guns, E.S.2    Lubik, A.A.3    Adomat, H.H.4    Hendy, S.C.5    Wood, C.A.6
  • 11
    • 80054021222 scopus 로고    scopus 로고
    • Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors
    • Cai C, Chen S, Ng P, Bubley GJ, Nelson PS, Mostaghel EA, et al. Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors. Cancer Res 2011;71:6503-13.
    • (2011) Cancer Res , vol.71 , pp. 6503-6513
    • Cai, C.1    Chen, S.2    Ng, P.3    Bubley, G.J.4    Nelson, P.S.5    Mostaghel, E.A.6
  • 12
    • 84875932058 scopus 로고    scopus 로고
    • Abiraterone in metastatic prostate cancer
    • Ryan CJ, Molina A, Griffin T. Abiraterone in metastatic prostate cancer. N Engl J Med 2013;368:1458-9.
    • (2013) N Engl J Med , vol.368 , pp. 1458-1459
    • Ryan, C.J.1    Molina, A.2    Griffin, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.