-
1
-
-
84907393368
-
Canonical androstenedione reduction is the predominant source of signaling androgens in hormone-refractory prostate cancer
-
Frankhauser M, Tan Y, Macintyre G, Haviv I, Hong MKH, Nguyen A, et al. Canonical androstenedione reduction is the predominant source of signaling androgens in hormone-refractory prostate cancer. Clin Cancer Res 2014;20:5547-57.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 5547-5557
-
-
Frankhauser, M.1
Tan, Y.2
Macintyre, G.3
Haviv, I.4
Hong, M.K.H.5
Nguyen, A.6
-
2
-
-
84890259591
-
Molecular pathology and prostate cancer therapeutics: From biology to bedside
-
Rodrigues DN, Butler LM, Estelles DL, de Bono JS. Molecular pathology and prostate cancer therapeutics: from biology to bedside. J Pathol 2014;232:178-84.
-
(2014)
J Pathol
, vol.232
, pp. 178-184
-
-
Rodrigues, D.N.1
Butler, L.M.2
Estelles, D.L.3
De Bono, J.S.4
-
3
-
-
79956103537
-
Outsmarting androgen receptor: Creative approaches for targeting aberrant androgen signaling in advanced prostate cancer
-
Knudsen KE, Kelly WK. Outsmarting androgen receptor: creative approaches for targeting aberrant androgen signaling in advanced prostate cancer. Expert Rev Endocrinol Metab 2011;6:483-93.
-
(2011)
Expert Rev Endocrinol Metab
, vol.6
, pp. 483-493
-
-
Knudsen, K.E.1
Kelly, W.K.2
-
4
-
-
84900373381
-
Targeting the androgen receptor pathway in castration-resistant prostate cancer: Progresses and prospects
-
May 19. [Epub ahead of print]
-
Ferraldeschi R, Welti J, Luo J, Attard G, de Bono JS. Targeting the androgen receptor pathway in castration-resistant prostate cancer: progresses and prospects. Oncogene 2014 May 19. [Epub ahead of print].
-
(2014)
Oncogene
-
-
Ferraldeschi, R.1
Welti, J.2
Luo, J.3
Attard, G.4
De Bono, J.S.5
-
5
-
-
77952554163
-
Partners in crime: Deregulation of AR activity and androgen synthesis in prostate cancer
-
Knudsen KE, Penning TM. Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer. Trends Endocrinol Metab 2010;21:315-24.
-
(2010)
Trends Endocrinol Metab
, vol.21
, pp. 315-324
-
-
Knudsen, K.E.1
Penning, T.M.2
-
6
-
-
84910013455
-
Androgen metabolism in prostate cancer: From molecular mechanisms to clinical consequences
-
Chang KH, Ercole CE, Sharifi N. Androgen metabolism in prostate cancer: from molecular mechanisms to clinical consequences. Br J Cancer 2014;111:1249-54.
-
(2014)
Br J Cancer
, vol.111
, pp. 1249-1254
-
-
Chang, K.H.1
Ercole, C.E.2
Sharifi, N.3
-
7
-
-
33645056171
-
Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
-
Stanbrough M, Bubley GJ, Ross K, Golub TR, Rubin MA, Penning TM, et al. Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer Res 2006;66:2815-25.
-
(2006)
Cancer Res
, vol.66
, pp. 2815-2825
-
-
Stanbrough, M.1
Bubley, G.J.2
Ross, K.3
Golub, T.R.4
Rubin, M.A.5
Penning, T.M.6
-
8
-
-
49249119358
-
Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth
-
Montgomery RB, Mostaghel EA, Vessella R, Hess DL, Kalhorn TF, Higano CS, et al. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res 2008;68:4447-54.
-
(2008)
Cancer Res
, vol.68
, pp. 4447-4454
-
-
Montgomery, R.B.1
Mostaghel, E.A.2
Vessella, R.3
Hess, D.L.4
Kalhorn, T.F.5
Higano, C.S.6
-
9
-
-
34250331066
-
Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: Therapeutic implications for castration-resistant prostate cancer
-
Mostaghel EA, Page ST, Lin DW, Fazli L, Coleman IM, True LD, et al. Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer. Cancer Res 2007;67:5033-41.
-
(2007)
Cancer Res
, vol.67
, pp. 5033-5041
-
-
Mostaghel, E.A.1
Page, S.T.2
Lin, D.W.3
Fazli, L.4
Coleman, I.M.5
True, L.D.6
-
10
-
-
51049098138
-
Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
-
Locke JA, Guns ES, Lubik AA, Adomat HH, Hendy SC, Wood CA, et al. Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer Res 2008;68:6407-15.
-
(2008)
Cancer Res
, vol.68
, pp. 6407-6415
-
-
Locke, J.A.1
Guns, E.S.2
Lubik, A.A.3
Adomat, H.H.4
Hendy, S.C.5
Wood, C.A.6
-
11
-
-
80054021222
-
Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors
-
Cai C, Chen S, Ng P, Bubley GJ, Nelson PS, Mostaghel EA, et al. Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors. Cancer Res 2011;71:6503-13.
-
(2011)
Cancer Res
, vol.71
, pp. 6503-6513
-
-
Cai, C.1
Chen, S.2
Ng, P.3
Bubley, G.J.4
Nelson, P.S.5
Mostaghel, E.A.6
-
12
-
-
84875932058
-
Abiraterone in metastatic prostate cancer
-
Ryan CJ, Molina A, Griffin T. Abiraterone in metastatic prostate cancer. N Engl J Med 2013;368:1458-9.
-
(2013)
N Engl J Med
, vol.368
, pp. 1458-1459
-
-
Ryan, C.J.1
Molina, A.2
Griffin, T.3
|