Using pure shift HSQC to characterize microgram samples of drug metabolites

Tetrahedron Letters

Volumn 55, Issue 40, 2014, Pages 5450-5453

  Liu, Yong ^a   Green, Mitchell D ^a   Marques, Rosemary ^a   Pereira, Tony ^a   Helmy, Roy ^a   Thomas Williamson, R ^a   Bermel, Wolfgang ^b   Martin, Gary E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b BRUKER BIOSPIN GMBH   (Germany)

Author keywords

3 Hydroxy amiodarone; 3 Hydroxy carbamazepine; HSQC heteronuclear single quantum coherence; Metabolite structure characterization; Pure shift NMR

Indexed keywords

AMIODARONE; CARBAMAZEPINE; CYTOCHROME P450 2J2; DRUG METABOLITE; RECOMBINANT ENZYME; SOLVENT;

ARTICLE; HETERONUCLEAR SINGLE QUANTUM COHERENCE; NUCLEAR MAGNETIC RESONANCE; SIGNAL NOISE RATIO;

EID: 84910079728     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2014.06.067     Document Type: Article

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