Importance of a specific amino acid pairing for murine MLL leukemias driven by MLLT1/3 or AFF1/4

Leukemia Research

Volumn 38, Issue 11, 2014, Pages 1309-1315

  Lokken, Alyson A ^a   Achille, Nicholas J ^a   Chang, Ming Jin ^b   Lin, Jeffrey J ^b   Kuntimaddi, Aravinda ^c   Leach, Benjamin I ^c   Malik, Bhavna ^a   Nesbit, Jacqueline B ^b   Zhang, Shubin ^a   Bushweller, John H ^c   Zeleznik Le, Nancy J ^a   Hemenway, Charles S ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Leukemic transformation; Mutation complementation; Oncoproteins; Protein binding

Indexed keywords

AFF1 PROTEIN; AFF4 PROTEIN; HYBRID PROTEIN; MLLT1 PROTEIN; MLLT3 PROTEIN; ONCOPROTEIN; UNCLASSIFIED DRUG; AFF4 PROTEIN, MOUSE; AMINO ACID; DNA BINDING PROTEIN; MLLT1 PROTEIN, MOUSE; MLLT3 PROTEIN, MOUSE; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR;

AMINO ACID PAIRING; ANIMAL CELL; ARTICLE; CELL TRANSFORMATION; COMPLEX FORMATION; GENETIC COMPLEMENTATION; HEMATOPOIETIC STEM CELL; MOUSE; MURINE LEUKEMIA; MURINE MIXED LINEAGE LEUKEMIA; MUTATIONAL ANALYSIS; NONHUMAN; POINT MUTATION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; EXPERIMENTAL LEUKEMIA; GENETICS; HEK293 CELL LINE; HUMAN; MOLECULAR GENETICS; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; DNA-BINDING PROTEINS; HEK293 CELLS; HUMANS; LEUKEMIA, EXPERIMENTAL; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS;

EID: 84910070291     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2014.08.010     Document Type: Article

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