Magnitude of influenza virus replication and cell damage is associated with interleukin-6 production in primary cultures of human tracheal epithelium

Respiratory Physiology and Neurobiology

Volumn 202, Issue , 2014, Pages 16-23

  Yamaya, Mutsuo ^a   Nadine, Lusamba K ^a   Ota, Chiharu ^a   Kubo, Hiroshi ^a   Makiguchi, Tomonori ^a   Nagatomi, Ryoichi ^a   Nishimura, Hidekazu ^b  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SENDAI CITY MEDICAL CENTER   (Japan)

Author keywords

Airway epithelial cells; Cell damage; Influenza virus; Interleukin 6; Pathogenicity

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CAFFEIC ACID PHENETHYL ESTER; CASPASE 3; CASPASE 3 INHIBITOR; GAMMA INTERFERON; I KAPPA B; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR ANTIBODY; LACTATE DEHYDROGENASE; RECEPTOR ANTIBODY; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS RNA; ANTIBODY; BENZYLOXYCARBONYL-ASPARTYL-GLUTAMYL-VALYL-ASPARTYL-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN; COUMARIN DERIVATIVE; ENZYME INHIBITOR; MESSENGER RNA; OLIGOPEPTIDE; VIRUS PROTEIN;

ADULT; AGED; ANIMAL CELL; ARTICLE; CELL COUNT; CELL DAMAGE; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FEMALE; HONG KONG INFLUENZA; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLUENZA A (H1N1); INFLUENZA VIRUS; LIMIT OF DETECTION; MALE; MIDDLE AGED; NONHUMAN; PANDEMIC INFLUENZA; PICORNAVIRUS INFECTION; PRIMARY CULTURE; SENDAI VIRUS INFECTION; SUPERNATANT; TRACHEA MUCOSA; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE; AIRWAY RESISTANCE; ANALYSIS OF VARIANCE; ANIMAL; CAT; CELL CULTURE; CLASSIFICATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; INFLUENZA VIRUS A; METABOLISM; PATHOLOGY; PHYSIOLOGY; TIME; TRACHEA; VERY ELDERLY; VIROLOGY;

AGED; AGED, 80 AND OVER; AIRWAY RESISTANCE; ANALYSIS OF VARIANCE; ANIMALS; ANTIBODIES; CATS; CELLS, CULTURED; COUMARINS; ENZYME INHIBITORS; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, VIRAL; HUMANS; INFLUENZA A VIRUS; INTERLEUKIN-6; L-LACTATE DEHYDROGENASE; MALE; OLIGOPEPTIDES; RNA, MESSENGER; TIME FACTORS; TRACHEA; TRANSCRIPTION FACTOR RELA; TRANSFECTION; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84910039398     PISSN: 15699048     EISSN: 18781519     Source Type: Journal    
DOI: 10.1016/j.resp.2014.07.010     Document Type: Article

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