Crystal structure of the Bacillus subtilis phosphodiesterase PhoD reveals an iron and calcium-containing active site

Journal of Biological Chemistry

Volumn 289, Issue 45, 2014, Pages 30889-30899

  Rodriguez, Fernanda ^a,b   Lillington, James ^b,c,d   Johnson, Steven ^b   Timmel, Christiane R ^c   Lea, Susan M ^b   Berks, Ben C ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOLOGY; CALCIUM; ENZYME INHIBITION; ESTERS; IRON COMPOUNDS; MANGANESE; METAL IONS; PHOSPHATASES;

ACTIVE SITE; ACTIVE SITE ARCHITECTURE; BACILLUS SUBTILIS; CATALYTIC CENTER; PHOSPHODIESTERASES; PHOSPHOLIPASE D; PRODUCT COMPLEX; PURPLE ACID PHOSPHATASE;

CRYSTAL STRUCTURE;

CALCIUM ION; IRON; MANGANESE; PHOSPHATE; PHOSPHODIESTERASE; PROTEIN PHOD; RECOMBINANT ENZYME; UNCLASSIFIED DRUG; ZINC ION; BACTERIAL PROTEIN; CALCIUM; LIGAND; METAL; PHOSPHATASE; TYROSINE; ZINC;

ARTICLE; BACILLUS SUBTILIS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PROTEIN EXPRESSION; AMINO ACID SEQUENCE; CHEMISTRY; ELECTRON SPIN RESONANCE; ENZYMOLOGY; MOLECULAR GENETICS; PH; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BACILLUS SUBTILIS; BACTERIAL PROTEINS; CALCIUM; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ELECTRON SPIN RESONANCE SPECTROSCOPY; HYDROGEN-ION CONCENTRATION; IRON; LIGANDS; METALS; MOLECULAR SEQUENCE DATA; PHOSPHORIC DIESTER HYDROLASES; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN STRUCTURE, SECONDARY; SEQUENCE HOMOLOGY, AMINO ACID; TYROSINE; ZINC;

EID: 84910025227     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.604892     Document Type: Article

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