Puerarin protects against β-amyloid-induced microglia apoptosis via a PI3K-dependent signaling pathway

Neurochemical Research

Volumn 39, Issue 11, 2014, Pages 2189-2196

  Wang, Cui ^a   Xie, Nanchang ^a   Zhang, Huiru ^b   Li, Yulin ^c   Wang, Yunlong ^a,c  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^b HENAN UNIVERSITY OF TECHNOLOGY   (China)

^c Henan Bioengineering Technology Research Center   (China)

Author keywords

Akt; Apoptosis; Microglia; Puerarin; amyloid

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; AMYLOID BETA PROTEIN; CASPASE 3; CYTOCHROME C; NEUROPROTECTIVE AGENT; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PUERARIN; REACTIVE OXYGEN METABOLITE; ISOFLAVONE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; INTRACELLULAR SIGNALING; MICROGLIA; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NEUROPROTECTION; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; METABOLISM; NERVE CELL; SIGNAL TRANSDUCTION;

AMYLOID BETA-PEPTIDES; ANIMALS; APOPTOSIS; CASPASE 3; CELLS, CULTURED; ISOFLAVONES; MICE, INBRED BALB C; MICROGLIA; NEURONS; NEUROPROTECTIVE AGENTS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

EID: 84910006635     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1420-1     Document Type: Article

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