Association of malectin with ribophorin i is crucial for attenuation of misfolded glycoprotein secretion

Biochemical and Biophysical Research Communications

Volumn 454, Issue 3, 2014, Pages 436-440

  Takeda, Koh ^a   Qin, Sheng Ying ^a   Matsumoto, Naoki ^a   Yamamoto, Kazuo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Glycoprotein quality control; Malectin; Misfolded protein; Ribophorin I

Indexed keywords

ALPHA 1 ANTITRYPSIN; CHAPERONE; GLYCOPROTEIN; LECTIN; MALECTIN; PROTEASOME INHIBITOR; RIBOPHORIN I; UNCLASSIFIED DRUG; LYSYL-ASPARTYL-GLUTAMYL-LEUCINE; MALECTIN PROTEIN, HUMAN; MEMBRANE PROTEIN; OLIGOPEPTIDE; RIBOPHORIN; SIGNAL PEPTIDE;

ARTICLE; CELL LYSATE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; EXPRESSION VECTOR; HELA CELL LINE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN SECRETION; CHEMISTRY; GENETICS; METABOLISM; MUTATION; PROTEIN PROTEIN INTERACTION; PROTEOSTASIS DEFICIENCY;

ALPHA 1-ANTITRYPSIN; HELA CELLS; HUMANS; LECTINS; MEMBRANE PROTEINS; MUTATION; OLIGOPEPTIDES; PROTEIN FOLDING; PROTEIN INTERACTION MAPS; PROTEIN SORTING SIGNALS; PROTEOLYSIS; PROTEOSTASIS DEFICIENCIES;

EID: 84909992890     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.10.102     Document Type: Article

References (18)

1. D.N. Hebert, R. Bernasconi, and M. Molinari ERAD substrates: which way out? Semin. Cell Dev. Biol. 21 2010 526 532
2. D.J. Kelleher, and R. Gilmore An evolving view of the eukaryotic oligosaccharyltransferase Glycobiology 16 2006 47R 62R
3. T. Schallus, C. Jaeckh, K. Feher, A.S. Palma, Y. Liu, J.C. Simpson, M. Mackeen, G. Stier, T.J. Gibson, T. Feizi, T. Pieler, and C. Muhle-Goll Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation Mol. Biol. Cell 19 2008 3404 3414
4. T. Schallus, K. Feher, U. Sternberg, V. Rybin, and C. Muhle-Goll Analysis of the specific interactions between the lectin domain of malectin and diglucosides Glycobiology 20 2010 1010 1020
5. 2-dependent quality control ofα1-antitrypsin Mol. Biol. Cell 22 2011 3559 3570
6. C. Galli, R. Bernasconi, T. Solda, V. Calanca, and M. Molinari Malectin participates in a backup glycoprotein quality control pathway in the mammalian ER PLoS one 6 2011 e16304
7. R.N. Sifers, S. Brashearsmacatee, V.J. Kidd, H. Muensch, and S.L.C. Woo A frameshift mutation results in a truncatedα1-antitrypsin that is retained within the rough endoplasmic-reticulum J. Biol. Chem. 263 1988 7330 7335
8. Y. Liu, P. Choudhury, C.M. Cabral, and R.N. Sifers Oligosaccharide modification in the early secretory pathway directs the selection of a misfolded glycoprotein for degradation by the proteasome J. Biol. Chem. 274 1999 5861 5867
9. N. Hosokawa, I. Wada, K. Hasegawa, T. Yorihuzi, L.O. Tremblay, A. Herscovics, and K. Nagata A novel ERα-mannosidase-like protein accelerates ER-associated degradation EMBO Rep. 2 2001 415 422
10. S.-Y. Qin, D. Hu, K. Matsumoto, K. Takeda, N. Matsumoto, Y. Yamaguchi, and K. Yamamoto Malectin forms a complex with ribophorin I for enhanced association with misfolded glycoproteins J. Biol. Chem. 287 2012 38080 38089
11. D.J. Kelleher, G. Kreibich, and R. Gilmore Oligosaccharyltransferase activity is associated with a protein complex composed of ribophorin-I and ribophorin-Ii and a 48 kd protein Cell 69 1992 55 65
12. C.M. Wilson, and S. High Ribophorin I acts as a substrate-specific facilitator of N-glycosylation J. Cell Sci. 120 2007 648 657
13. C.M. Wilson, Q. Roebuck, and S. High Ribophorin I regulates substrate delivery to the oligosaccharyltransferase core Proc. Natl. Acad. Sci. U.S.A. 105 2008 9534 9539
14. S.-Y. Qin, N. Kawasaki, D. Hu, H. Tozawa, N. Matsumoto, and K. Yamamoto Subcellular localization of ERGIC-53 under endoplasmic reticulum stress condition Glycobiology 22 2012 1709 1720
15. M. Capitani, and M. Sallese The KDEL receptor: new functions for an old protein FEBS Lett. 583 2009 3863 3871
16. L.L. Lanier, B.C. Corliss, J. Wu, C. Leong, and J.H. Phillips Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells Nature 391 1998 703 707
17. Y. Oda, N. Hosokawa, I. Wada, and K. Nagata EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin Science 299 2003 1394 1397
18. T. Shibatani, L.L. David, A.L. McCormack, K. Frueh, and W.R. Skach Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subuints Biochemistry 44 2005 5982 5992