TMPRSS2-ERG fusions are strongly linked to young patient age in low-grade prostate cancer

European Urology

Volumn 66, Issue 6, 2014, Pages 978-981

  Steurer, Stefan ^a   Mayer, Pascale Sophia ^a   Adam, Meike ^a   Krohn, Antje ^a   Koop, Christina ^a   Ospina Klinck, Daniel ^a   Tehrani, Ali Attarchi ^a   Simon, Ronald ^a   Tennstedt, Pierre ^a   Graefen, Markus ^a   Wittmer, Corinna ^a   Brors, Benedikt ^b   Plass, Christoph ^b   Korbel, Jan ^c   Weischenfeldt, Joachim ^c   Sauter, Guido ^a   Huland, Hartwig ^a   Tsourlakis, Maria Christina ^a   Minner, Sarah ^a   Schlomm, Thorsten ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

5q; 6q; Age; Deletion; Early onset; ERG; Gene fusion; Molecular; Prognosis; Prostate cancer; PTEN; Subtype; TMPRSS ERG

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; ERG PROTEIN, HUMAN; ONCOPROTEIN; PTEN PROTEIN, HUMAN; TESTOSTERONE; TMPRSS2-ERG FUSION PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN;

AGE; AGED; ARTICLE; CHROMOSOME 5Q; CHROMOSOME 6Q; CHROMOSOME ABERRATION; CHROMOSOME DELETION; DISEASE SEVERITY; FLUORESCENCE IN SITU HYBRIDIZATION; FUSION GENE; GENE ACTIVATION; GENETIC ASSOCIATION; GERIATRIC PATIENT; GLEASON SCORE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PROSTATE CANCER; TMPRSS2 ERG FUSION GENE; TUMOR MICROENVIRONMENT; ADULT; BLOOD; CANCER GRADING; CHROMOSOME 5; CHROMOSOME 6; GENE DELETION; GENE FUSION; GENETICS; GENOMIC INSTABILITY; MIDDLE AGED; NUCLEOTIDE SEQUENCE; PATHOLOGY; PROSTATE TUMOR; VERY ELDERLY;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; BASE SEQUENCE; CHROMOSOMES, HUMAN, PAIR 5; CHROMOSOMES, HUMAN, PAIR 6; GENE FUSION; GENOMIC INSTABILITY; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MIDDLE AGED; NEOPLASM GRADING; ONCOGENE PROTEINS, FUSION; PROSTATIC NEOPLASMS; PTEN PHOSPHOHYDROLASE; SEQUENCE DELETION; TESTOSTERONE; TRANS-ACTIVATORS;

EID: 84909974951     PISSN: 03022838     EISSN: 18737560     Source Type: Journal    
DOI: 10.1016/j.eururo.2014.06.027     Document Type: Article

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