An interleukin-4 polymorphism is associated with susceptibility to Clostridium difficile infection in patients with inflammatory bowel disease: Results of a retrospective cohort study

Surgery (United States)

Volumn 156, Issue 4, 2014, Pages 769-775

  Connelly, Tara M ^a   Koltun, Walter A ^a   Sangster, William ^a   Berg, Arthur S ^b   Hegarty, John P ^a   Harris, Leonard ^a   Deiling, Susan ^a   Stewart, David B ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4;

ADULT; ALLELE; ARTICLE; CLOSTRIDIUM DIFFICILE INFECTION; CROHN DISEASE; DISEASE PREDISPOSITION; FEMALE; GENOTYPE; HUMAN; IMMUNE DYSREGULATION; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; ULCERATIVE COLITIS; CASE CONTROL STUDY; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTION; COHORT ANALYSIS; GENETIC MARKER; GENETIC PREDISPOSITION; GENETICS; GENOTYPING TECHNIQUE; INFLAMMATORY BOWEL DISEASE; MIDDLE AGED; RISK FACTOR; STATISTICAL MODEL;

ADULT; CASE-CONTROL STUDIES; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; COHORT STUDIES; FEMALE; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPING TECHNIQUES; HUMANS; INFLAMMATORY BOWEL DISEASES; INTERLEUKIN-4; LOGISTIC MODELS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84909594621     PISSN: 00396060     EISSN: 15327361     Source Type: Journal    
DOI: 10.1016/j.surg.2014.06.067     Document Type: Article

References (25)

1. J.F. Rodemann, E.R. Dubberke, K.A. Reske, H. Seo da, and C.D. Stone Incidence of Clostridium difficile infection in inflammatory bowel disease Clin Gastroenterol Hepatol 5 2007 339 344
2. G.C. Nguyen, G.G. Kaplan, M.L. Harris, and S.R. Brant A national survey of the prevalence and impact of Clostridium difficile infection among hospitalized inflammatory bowel disease patients Am J Gastroenterol 103 2008 1443 1450
3. M. Issa, A. Vijayapal, M.B. Graham, D.B. Beaulieu, M.F. Otterson, and S. Lundeen et al. Impact of Clostridium difficile on inflammatory bowel disease Clin Gastroenterol Hepatol 5 2007 345 351
4. S.S. Reddy, and L.J. Brandt Clostridium difficile infection and inflammatory bowel disease J Clin Gastroenterol 47 2013 666 671
5. D.B. Stewart, and C.S. Hollenbeak Clostridium difficile colitis: factors associated with outcome and assessment of mortality at a national level J Gastrointest Surg 15 2011 1548 1555
6. J.O. Shim Gut microbiota in inflammatory bowel disease Pediatr Gastroenterol Hepatol Nutr 16 2013 17 21
7. L.J. Brandt American Journal of Gastroenterology Lecture: intestinal microbiota and the role of fecal microbiota transplant (FMT) in treatment of C. difficile infection Am J Gastroenterol 108 2013 177 185
8. S.K. Murthy, A.H. Steinhart, J. Tinmouth, P.C. Austin, N. Daneman, and G.C. Nguyen Impact of Clostridium difficile colitis on 5-year health outcomes in patients with ulcerative colitis Aliment Pharmacol Ther 36 2012 1032 1039
9. B.C. Marts, W.E. Longo, A.M. Vernava 3rd, D.J. Kennedy, G.L. Daniel, and I. Jones Patterns and prognosis of Clostridium difficile colitis Dis Colon Rectum 37 1994 837 845
10. A.N. Ananthakrishnan, E.C. Oxford, D.D. Nguyen, J. Sauk, V. Yajnik, and R.J. Xavier Genetic risk factors for Clostridium difficile infection in ulcerative colitis Aliment Pharmacol Ther 38 2013 522 530
11. G.A. West, T. Matsuura, A.D. Levine, J.S. Klein, and C. Fiocchi Interleukin 4 in inflammatory bowel disease and mucosal immune reactivity Gastroenterology 110 1996 1683 1695
12. G.P. Aithal, C.P. Day, J. Leathart, A.K. Daly, and M. Hudson Association of single nucleotide polymorphisms in the interleukin-4 gene and interleukin-4 receptor gene with Crohn's disease in a British population Genes Immun 2 2001 44 47
13. P. Desreumaux, E. Brandt, and L. Gambiez et al. Distinct cytokine patterns in early and chronic ileal lesions of Crohn's disease Gastroenterology 113 1997 118 126
14. K. Margolin, F.R. Aronson, and M. Sznol et al. Phase II studies of recombinant human interleukin-4 in advanced renal cancer and malignant melanoma J Immunother Emphasis Tumor Immunol 15 1994 147 153
15. S.P. Colgan, M.B. Resnick, C.A. Parkos, C. Delp-Archer, D. McGuirk, and A.E. Bacarra et al. IL-4 directly modulates function of a model human intestinal epithelium J Immunol 153 1994 2122 2129
16. J. Ng, S.A. Hirota, O. Gross, Y. Li, A. Ulke-Lemee, and M.S. Potentier et al. Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome Gastroenterology 139 2010 542 552 552.e1-3
17. A. Ryan, M. Lynch, S.M. Smith, S. Amu, H.J. Nel, and C.E. McCoy et al. A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins PLoS Pathog 7 2011 e1002076
18. Y. Miyake, K. Tanaka, and M. Arakawa Relationship between polymorphisms in IL4 and asthma in Japanese women: the Kyushu Okinawa Maternal and Child Health Study J Investig Allergol Clin Immunol 23 2013 242 247
19. M.H. Jen, S. Saxena, A. Bottle, P. Aylin, and R.C. Pollok Increased health burden associated with Clostridium difficile diarrhoea in patients with inflammatory bowel disease Aliment Pharmacol Ther 33 2011 1322 1331
20. D. Jodorkovsky, Y. Young, and M.T. Abreu Clinical outcomes of patients with ulcerative colitis and co-existing Clostridium difficile infection Dig Dis Sci 55 2010 415 420
21. U. Navaneethan, S. Mukewar, P.G. Venkatesh, R. Lopez, and B. Shen Clostridium difficile infection is associated with worse long term outcome in patients with ulcerative colitis J Crohns Colitis 6 2012 330 336
22. P. Bossuyt, J. Verhaegen, G. Van Assche, P. Rutgeerts, and S. Vermeire Increasing incidence of Clostridium difficile-associated diarrhea in inflammatory bowel disease J Crohns Colitis 3 2009 4 7
23. R. Kariv, U. Navaneethan, P.G. Venkatesh, R. Lopez, and B. Shen Impact of Clostridium difficile infection in patients with ulcerative colitis J Crohns Colitis 5 2011 34 40
24. S.J. Lundeen, M.F. Otterson, D.G. Binion, E.T. Carman, and W.J. Peppard Clostridium difficile enteritis: an early postoperative complication in inflammatory bowel disease patients after colectomy J Gastrointest Surg 11 2007 138 142
25. C. Greenfield, J.R. Aguilar Ramirez, and R.E. Pounder et al. Clostridium difficile and inflammatory bowel disease Gut 24 1983 713 717