Nanoparticle vesicle encoding for imaging and tracking cell populations

Nature Methods

Volumn 11, Issue 11, 2014, Pages 1177-1181

  Rees, Paul ^a,b   Wills, John W ^a   Brown, M Rowan ^a   Tonkin, James ^a   Holton, Mark D ^a   Hondow, Nicole ^c   Brown, Andrew P ^c   Brydson, Rik ^c   Millar, Val ^d   Carpenter, Anne E ^b   Summers, Huw D ^a  

^a SWANSEA UNIVERSITY   (United Kingdom)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c UNIVERSITY OF LEEDS   (United Kingdom)

^d GE HEALTHCARE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NANOPARTICLE; QUANTUM DOT; FLUORESCENT DYE;

ARTICLE; CELL ASSAY; CELL HETEROGENEITY; CELL LABELING; CELL LINE; CELL POPULATION; CELL TRACKING; CELL VACUOLE; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; TIME LAPSE IMAGING; PROCEDURES;

CELL LINE; CELL TRACKING; FLUORESCENT DYES; HUMANS; MICROSCOPY, FLUORESCENCE; QUANTUM DOTS;

EID: 84908602693     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.3105     Document Type: Article

References (27)

1. Axelrod, R., Axelrod, D.E. &Pienta, K.J. Evolution of cooperation among tumor cells. Proc. Natl. Acad. Sci. USA 103, 13474-13479 (2006
2. Eliceiri, K.W, et al. Biological imaging software tools. Nat. Methods 9, 697-710 (2012
3. Perlman, Z.E, et al. Multidimensional drug profiling by automated microscopy. Science 306, 1194-1198 (2004
4. Rajaram, S., Pavie, B., Wu, L.F. &Altschuler, S.J. PhenoRipper: software for rapidly profiling microscopy images. Nat. Methods 9, 635-637 (2012
5. Snijder, B, et al. Population context determines cell-To-cell variability in endocytosis and virus infection. Nature 461, 520-523 (2009
6. Snijder, B. &Pelkmans, L. Origins of regulated cell-To-cell variability. Nat. Rev. Mol. Cell Biol. 12, 119-125 (2011
7. Ho, M.M., Ng, A.V., Lam, S. &Hung, J.Y. Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res. 67, 4827-4833 (2007
8. Huang, S. Non-genetic heterogeneity of cells in Development: more than just noise. Development 136, 3853-3862 (2009
9. Bruchez, M. Jr., Moronne, M., Gin, P., Weiss, S. &Alivisatos, A.P. Semiconductor nanocrystals as fluorescent biological labels. Science 281, 2013-2016 (1998
10. Jaiswal, J.K., Mattoussi, H., Mauro, J.M. &Simon, S.M. Long-Term multiple color imaging of live cells using quantum dot bioconjugates. Nat. Biotechnol. 21, 47-51 (2003
11. Brown, M.R, et al. Long-Term time series analysis of quantum dot encoded cells by deconvolution of the autofluorescence signal. Cytometry A 77, 925-932 (2010
12. Parak, W.J., Pellegrino, T. &Plank, C. Labelling of cells with quantum dots. Nanotechnology 16, R9-R25 (2005
13. Koo, O.M., Rubinstein, I. &Onyuksel, H. Role of nanotechnology in targeted drug delivery and imaging: a concise review. Nanomedicine 1, 193-212 (2005
14. Ferrari, M. Cancer nanotechnology: opportunities and challenges. Nat. Rev. Cancer 5, 161-171 (2005
15. Chan, W.C.W, et al. Luminescent quantum dots for multiplexed biological detection and imaging. Curr. Opin. Biotechnol. 13, 40-46 (2002
16. Alivisatos, P. The use of nanocrystals in biological detection. Nat. Biotechnol. 22, 47-52 (2004
17. Fournier-Bidoz, S, et al. Facile and rapid one-step mass preparation of quantum-dot barcodes. Angew. Chem. Int. Ed. Engl. 47, 5577-5581 (2008
18. Stsiapura, V, et al. Functionalized nanocrystal-Tagged fluorescent polymer beads: synthesis, physicochemical characterization, and immunolabeling application. Anal. Biochem. 334, 257-265 (2004
19. Han, M., Gao, X., Su, J.Z. &Nie, S. Quantum-dot-Tagged microbeads for multiplexed optical coding of biomolecules. Nat. Biotechnol. 19, 631-635 (2001
20. Summers, H.D, et al. Statistical analysis of nanoparticle dosing in a dynamic cellular system. Nat. Nanotechnol. 6, 170-174 (2011
21. Scita, G. &Di Fiore, P.P. The endocytic matrix. Nature 463, 464-473 (2010
22. Errington, R.J, et al. Single cell nanoparticle tracking to model cell cycle dynamics and compartmental inheritance. Cell Cycle 9, 121-130 (2010
23. Wilhelm, C., Gazeau, F., Roger, J., Pons, J.N. &Bacri, J.-C. Interaction of anionic superparamagnetic nanoparticles with cells: kinetic analyses of membrane adsorption and subsequent internalization. Langmuir 18, 8148-8155 (2002
24. Tonkin, J.A, et al. Automated cell identification and tracking using nanoparticle moving-light-displays. PLoS ONE 7, e40835 (2012
25. Jaqaman, K, et al. Robust single-particle tracking in live-cell time-lapse sequences. Nat. Methods 5, 695-702 (2008
26. Carpenter, A.E, et al. CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol. 7, R100 (2006
27. Kim, J.A., Åberg, C., Salvati, A. &Dawson, K.A. Role of cell cycle on the cellular uptake and dilution of nanoparticles in a cell population. Nat. Nanotechnol. 7, 62-68 (2012