Packed red blood cell transfusion is not associated with increased risk of necrotizing enterocolitis in premature infants

Journal of Perinatology

Volumn 34, Issue 11, 2014, Pages 858-862

  Sharma, R ^a   Kraemer, D F ^a   Torrazza, R M ^a   Mai, V ^a   Neu, J ^a   Shuster, J J ^a   Hudak, M L ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; ENTERIC FEEDING; ERYTHROCYTE TRANSFUSION; FEMALE; FETUS OUTCOME; GENDER; GESTATIONAL AGE; HIGH RISK INFANT; HUMAN; INTESTINE PERFORATION; MAJOR CLINICAL STUDY; MALE; NECROTIZING ENTEROCOLITIS; NEWBORN; OBSERVATIONAL STUDY; ONSET AGE; OUTCOME ASSESSMENT; PNEUMOPERITONEUM; PREMATURITY; PROPHYLAXIS; PROSPECTIVE STUDY; RISK ASSESSMENT; CLINICAL TRIAL; ENTEROCOLITIS, NECROTIZING; INFANT, PREMATURE, DISEASES; MULTICENTER STUDY; PROCEDURES; PROPORTIONAL HAZARDS MODEL; RISK FACTOR; STATISTICAL ANALYSIS;

ENTEROCOLITIS, NECROTIZING; ERYTHROCYTE TRANSFUSION; FEMALE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; MALE; MATCHED-PAIR ANALYSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 84908598853     PISSN: 07438346     EISSN: 14765543     Source Type: Journal    
DOI: 10.1038/jp.2014.59     Document Type: Article

References (33)

1. Neu J, Walker WA. Necrotizing enterocolitis. N Engl J Med 2011; 364: 255-264
2. Sharma R, Hudak ML. A clinical perspective of necrotizing enterocolitis: past, present, and future. Clin Perinatol 2013; 40: 27-51
3. Wiedmeier SE, Henry E, Baer VL, Stoddard RA, Eggert LD, Lambert DK et al. Center differences in NEC within one health-care system may depend on feeding protocol. Am J Perinatol 2008; 25: 5-11
4. Hay WW Jr. Strategies for feeding the preterm infant. Neonatology 2008; 94: 245-254
5. Nanthakumar N, Meng D, Goldstein AM, Zhu W, Lu L, Uauy R et al. The mechanism of excessive intestinal inflammation in necrotizing enterocolitis: an immature innate immune response. PloS One 2011; 6: e17776.
6. Sharma R, Tepas JJ 3rd, Hudak ML, Mollitt DL, Wludyka PS, Teng R-J et al. Neonatal gut barrier and multiple organ failure: role of endotoxin and proinflammatory cytokines in sepsis and necrotizing enterocolitis. J Pediatr Surg 2007; 42: 454-461
7. Mai V, Young CM, Ukhanova M, Wang X, Sun Y, Casella G et al. Fecal microbiota in premature infants prior to necrotizing enterocolitis. PloS One 2011; 6: e20647.
8. Mally P, Golombek SG, Mishra R, Nigam S, Mohandas K, Depalma H et al. Association of necrotizing enterocolitis with elective packed red blood cell transfusions in stable, growing, premature neonates. Am J Perinatol 2006; 23: 451-458
9. Christensen RD, Lambert DK, Henry E, Wiedmeier SE, Snow GL, Baer VL et al. Is transfusion-associated necrotizing enterocolitis an authentic pathogenic entity? Transfusion 2010; 50: 1106-1112
10. Paul DA, Mackley A, Novitsky A, Zhao Y, Brooks A, Locke RG. Increased odds of necrotizing enterocolitis after transfusion of red blood cells in premature infants. Pediatrics 2011; 127: 635-641
11. Blau J, Calo JM, Dozor D, Sutton M, Alpan G, La Gamma EF. Transfusion-related acute gut injury: necrotizing enterocolitis in very low birth weight neonates after packed red blood cell transfusion. J Pediatr 2011; 158: 403-409
12. Demirel G, Celik IH, Aksov HT, Erdeve D, Oguz SS, Uras N et al. Transfusionassociated necrotising enterocolitis in very low birth weight premature infants. Transfus Med 2012; 22: 332-337
13. Elabiad MT, Harsono M, Talati AJ, Dhanireddy R. Effect of birth weight on the association between necrotising enterocolitis and red blood cell transfusions in ≤1500 g infants. BMJ Open 2013; 3: e003823.
14. Miner CA, Fullmer S, Eggett DL, Christensen RD. Factors affecting the severity of necrotizing enterocolitis. J Matern Fetal Neonatal Med 2013; 26: 1715-1719
15. Josephson CD, Wesolowski A, Bao G, Sola-Visner MC, Dudell G, Castillejo MI et al. Do red cell transfusions increase the risk of necrotizing enterocolitis in premature infants? J Pediatr 2010; 157(972-978): e1-e3
16. El-Dib M, Narang S, Lee E, Massaro AN, Aly H. Red blood cell transfusion, feeding and necrotizing enterocolitis in preterm infants. J Perinatol 2011; 31: 183-187
17. Singh R, Visintainer PF, Frantz ID 3rd, Shah BL, Meyer KM, Favila SA et al. Association of necrotizing enterocolitis with anemia and packed red blood cell transfusions in preterm infants. J Perinatol 2011; 31: 176-182
18. Stritzke AI, Smyth J, Synnes A, Lee SK, Shah PS. Transfusion-associated necrotising enterocolitis in neonates. Arch Dis Child Fetal Neonatal Ed 2013; 98: F10-F14
19. Wan-Huen P, Bateman D, Shapiro DM, Parravicini E. Packed red blood cell transfusion is an independent risk factor for necrotizing enterocolitis in premature infants. J Perinatol 2013; 33: 786-790
20. Martin FG, Sáenz de Pipaón M, Perez Rodriguez J, Jimenez JG. Risk factors for the development of necrotizing enterocolitis: a case-control study. J Neonatal Perinatal Med 2013; 6: 311-318
21. Kirpalani H, Zupancic JA. Do transfusions cause necrotizing enterocolitis? The complementary role of randomized trials and observational studies. Semin Perinatol 2012; 36: 269-276
22. Ballard JL, Khoury JC, Wedig K, Wang L, Eilers-Walsman BL, Lipp R. New Ballard Score expanded to include extremely premature infants. J Pediatr 1991; 119: 417-423
23. Bell MJ, Ternberg JL, Feigin RD, Keating JP, Marshall R, Barton L et al. Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging. Ann Surg 1978; 187: 1-7
24. Strauss RG. Data-driven blood banking practices for neonatal RBC transfusions. Transfusion 2000; 40: 1528-1540
25. Roseff SD, Luban NL, Manno CS. Guidelines for assessing appropriateness of pediatric transfusion. Transfusion 2002; 42: 1398-1413
26. SAS for Windows, Version 9.3. SAS Institute, Cary, NC, USA. 2002-2010
27. Papile LA, Burstein J, Burstein R, Koffler H. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr 1978; 92: 529-534
28. Tugwell P, Haynes B. Assessing claims of causation. In: Haynes RB, Sackett DL, Guyatt GH, Tugwell P (eds). Clinical Epidemiology: How to do clinical practice research, 3rd edn. Lippincott, Williams and Wilkins: New York, NY, 2005, pp 356-381
29. Young CM, Kingma SD, Neu J. Ischemia-reperfusion and neonatal intestinal injury. J Pediatr 2011; 158(2 Suppl): e25-e28
30. Mohamed A, Shah PS. Transfusion associated necrotizing enterocolitis: a metaanalysis of observational data. Pediatrics 2012; 129: 529-540
31. Ng EW, Poon TC, Lam HS, Cheung HM, Ma TP, Chan KY et al. Gut-associated biomarkers L-FABP, I-FABP, and TFF3 and LIT score for diagnosis of surgical necrotizing enterocolitis in preterm infants. Ann Surg 2013; 258: 1111-1118
32. Bell EF, Strauss RG, Widness JA, Mahoney LT, Mock DM, Seward VJ et al. Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants. Pediatrics 2005; 115: 1685-1691
33. Kirpalani H, Whyte RK, Andersen C, Asztalos EV, Heddle N, Blajchman MA et al. The premature infants in need of transfusion (PINT) study: a randomized, controlled trial of a restrictive (low) versus liberal (high) transfusion threshold for extremely low birth weight infants. J Pediatr 2006; 149: 301-307.