메뉴 건너뛰기




Volumn 20, Issue 19, 2014, Pages 5133-5139

The prostate cancer susceptibility variant rs2735839 near KLK3 gene is associated with aggressive prostate cancer and can stratify gleason score 7 patients

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DOWNSTREAM PROCESSING; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GLEASON SCORE; GLEASON SCORE 7; HISTOLOGY; HUMAN; HUMAN TISSUE; KLK3 GENE; MAJOR CLINICAL STUDY; MALE; PROSTATE BIOPSY; PROSTATE CANCER; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR GENE; ALLELE; BIOPSY; CANCER GRADING; CANCER STAGING; DISEASE COURSE; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; ODDS RATIO; PATHOLOGY; PROSTATIC NEOPLASMS; VERY ELDERLY;

EID: 84908583936     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-14-0661     Document Type: Article
Times cited : (33)

References (40)
  • 1
    • 70349140531 scopus 로고    scopus 로고
    • Outcomes of localized prostate cancer following conservative management
    • Lu-Yao GL, Albertsen PC, Moore DF, Shih W, Lin Y, DiPaola RS, et al. Outcomes of localized prostate cancer following conservative management. JAMA 2009;302:1202-9.
    • (2009) JAMA , vol.302 , pp. 1202-1209
    • Lu-Yao, G.L.1    Albertsen, P.C.2    Moore, D.F.3    Shih, W.4    Lin, Y.5    DiPaola, R.S.6
  • 2
    • 84870506614 scopus 로고    scopus 로고
    • Outcome following active surveillance of men with screen-detected prostate cancer. Results from the Goteborg randomised population-based prostate cancer screening trial
    • Godtman RA, Holmberg E, Khatami A, Stranne J, Hugosson J. Outcome following active surveillance of men with screen-detected prostate cancer. Results from the Goteborg randomised population-based prostate cancer screening trial. Eur Urol 2013;63:101-7.
    • (2013) Eur Urol , vol.63 , pp. 101-107
    • Godtman, R.A.1    Holmberg, E.2    Khatami, A.3    Stranne, J.4    Hugosson, J.5
  • 4
    • 84881609784 scopus 로고    scopus 로고
    • Defining the threshold for significant versus insignificant prostate cancer
    • Van der Kwast TH, Roobol MJ. Defining the threshold for significant versus insignificant prostate cancer. Nat Rev Urol 2013;10:473-82.
    • (2013) Nat Rev Urol , vol.10 , pp. 473-482
    • Van Der Kwast, T.H.1    Roobol, M.J.2
  • 5
    • 33750516605 scopus 로고    scopus 로고
    • Pooled genome linkage scan of aggressive prostate cancer: Results from the International Consortium for Prostate Cancer Genetics
    • Schaid DJ, McDonnell SK, Zarfas KE, Cunningham JM, Hebbring S, Thibodeau SN, et al. Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer Genetics. Hum Genet 2006;120:471-85.
    • (2006) Hum Genet , vol.120 , pp. 471-485
    • Schaid, D.J.1    McDonnell, S.K.2    Zarfas, K.E.3    Cunningham, J.M.4    Hebbring, S.5    Thibodeau, S.N.6
  • 6
    • 67650609664 scopus 로고    scopus 로고
    • Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients
    • Kader AK, Sun J, Isaacs SD, Wiley KE, Yan G, Kim ST, et al.Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients. Prostate 2009;69:1195-205.
    • (2009) Prostate , vol.69 , pp. 1195-1205
    • Kader, A.K.1    Sun, J.2    Isaacs, S.D.3    Wiley, K.E.4    Yan, G.5    Kim, S.T.6
  • 7
    • 79955805321 scopus 로고    scopus 로고
    • Association of prostate cancer risk loci with disease aggressiveness and prostate cancer-specific mortality
    • Pomerantz MM, Werner L, Xie W, Regan MM, Lee GS, Sun T, et al. Association of prostate cancer risk loci with disease aggressiveness and prostate cancer-specific mortality. Cancer Prev Res 2011;4: 719-28.
    • (2011) Cancer Prev Res , vol.4 , pp. 719-728
    • Pomerantz, M.M.1    Werner, L.2    Xie, W.3    Regan, M.M.4    Lee, G.S.5    Sun, T.6
  • 8
    • 84871603324 scopus 로고    scopus 로고
    • A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease
    • Amin Al Olama A, Kote-Jarai Z, Schumacher FR, Wiklund F, Berndt SI, Benlloch S, et al. A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease. Hum Mol Genet 2013;22:408-15.
    • (2013) Hum Mol Genet , vol.22 , pp. 408-415
    • Amin Al Olama, A.1    Kote-Jarai, Z.2    Schumacher, F.R.3    Wiklund, F.4    Berndt, S.I.5    Benlloch, S.6
  • 9
    • 24144493035 scopus 로고    scopus 로고
    • The 2005 international society of urological pathology (ISUP) consensus conference on gleason grading of prostatic carcinoma
    • Epstein JI, Allsbrook WC Jr, Amin MB, Egevad LL. The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason grading of prostatic carcinoma. Am J Surg Pathol 2005; 29:1228-42.
    • (2005) Am J Surg Pathol , vol.29 , pp. 1228-1242
    • Epstein, J.I.1    Allsbrook, W.C.2    Amin, M.B.3    Egevad, L.L.4
  • 10
    • 0032538069 scopus 로고    scopus 로고
    • Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer
    • D'Amico AV, Whittington R, Malkowicz SB, Schultz D, Blank K, Broderick GA, et al. Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer. JAMA 1998;280:969-74.
    • (1998) JAMA , vol.280 , pp. 969-974
    • D'Amico, A.V.1    Whittington, R.2    Malkowicz, S.B.3    Schultz, D.4    Blank, K.5    Broderick, G.A.6
  • 11
    • 0032006961 scopus 로고    scopus 로고
    • Observations on pathology trends in 62,537 prostate biopsies obtained from urology private practices in the united states
    • Orozco R, O'Dowd G, Kunnel B, Miller MC, Veltri RW. Observations on pathology trends in 62,537 prostate biopsies obtained from urology private practices in the United States. Urology 1998;51:186-95.
    • (1998) Urology , vol.51 , pp. 186-195
    • Orozco, R.1    O'Dowd, G.2    Kunnel, B.3    Miller, M.C.4    Veltri, R.W.5
  • 12
    • 0033782887 scopus 로고    scopus 로고
    • Gleason score 7 prostate cancer: A heterogeneous entity? Correlation with pathologic parameters and disease-free survival
    • Sakr WA, Tefilli MV, Grignon DJ, Banerjee M, Dey J, Gheiler EL, et al. Gleason score 7 prostate cancer: a heterogeneous entity? Correlation with pathologic parameters and disease-free survival. Urology 2000;56:730-4.
    • (2000) Urology , vol.56 , pp. 730-734
    • Sakr, W.A.1    Tefilli, M.V.2    Grignon, D.J.3    Banerjee, M.4    Dey, J.5    Gheiler, E.L.6
  • 13
    • 0033787042 scopus 로고    scopus 로고
    • Prognostic significance of gleason score 34 versus gleason score 43 tumor at radical prostatectomy
    • Chan TY, Partin AW, Walsh PC, Epstein JI. Prognostic significance of Gleason score 34 versus Gleason score 43 tumor at radical prostatectomy. Urology 2000;56:823-7.
    • (2000) Urology , vol.56 , pp. 823-827
    • Chan, T.Y.1    Partin, A.W.2    Walsh, P.C.3    Epstein, J.I.4
  • 14
    • 84859426392 scopus 로고    scopus 로고
    • Upgrading and downgrading of prostate cancer from biopsy to radical prostatectomy: Incidence and predictive factors using the modified gleason grading system and factoring in tertiary grades
    • Epstein JI, Feng Z, Trock BJ, Pierorazio PM. Upgrading and downgrading of prostate cancer from biopsy to radical prostatectomy: incidence and predictive factors using the modified Gleason grading system and factoring in tertiary grades. Eur Urol 2012;61: 1019-24.
    • (2012) Eur Urol , vol.61 , pp. 1019-1024
    • Epstein, J.I.1    Feng, Z.2    Trock, B.J.3    Pierorazio, P.M.4
  • 15
    • 84868206960 scopus 로고    scopus 로고
    • Genome-wide association study in chinese men identifies two new prostate cancer risk loci at 9Q31.2 and 19q13.4
    • Xu J,Mo Z, Ye D, Wang M, Liu F, Jin G, et al. Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4. Nat Genet 2012;44:1231-5.
    • (2012) Nat Genet , vol.44 , pp. 1231-1235
    • Xu, J.1    Mo, Z.2    Ye, D.3    Wang, M.4    Liu, F.5    Jin, G.6
  • 17
    • 79960924160 scopus 로고    scopus 로고
    • Seven prostate cancer susceptibility loci identified by a multistage genome-wide association study
    • Kote-Jarai Z, Olama AA, Giles GG, Severi G, Schleutker J, Weischer M, et al. Seven prostate cancer susceptibility loci identified by a multistage genome-wide association study. Nat Genet 2011;43:785-91.
    • (2011) Nat Genet , vol.43 , pp. 785-791
    • Kote-Jarai, Z.1    Olama, A.A.2    Giles, G.G.3    Severi, G.4    Schleutker, J.5    Weischer, M.6
  • 18
    • 39749118602 scopus 로고    scopus 로고
    • Multiple loci identified in a genome-wide association study of prostate cancer
    • Thomas G, Jacobs KB, Yeager M, Kraft P, Wacholder S, Orr N, et al. Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet 2008;40:310-5.
    • (2008) Nat Genet , vol.40 , pp. 310-315
    • Thomas, G.1    Jacobs, K.B.2    Yeager, M.3    Kraft, P.4    Wacholder, S.5    Orr, N.6
  • 19
  • 20
    • 70349547128 scopus 로고    scopus 로고
    • Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility
    • Gudmundsson J, Sulem P, Gudbjartsson DF, Blondal T, Gylfason A, Agnarsson BA, et al. Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility. Nat Genet 2009;41:1122-6.
    • (2009) Nat Genet , vol.41 , pp. 1122-1126
    • Gudmundsson, J.1    Sulem, P.2    Gudbjartsson, D.F.3    Blondal, T.4    Gylfason, A.5    Agnarsson, B.A.6
  • 21
    • 77956637724 scopus 로고    scopus 로고
    • Genome-wide association study identifies five new susceptibility loci for prostate cancer in the japanese population
    • Takata R, Akamatsu S, Kubo M, Takahashi A, Hosono N, Kawaguchi T, et al. Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population. Nat Genet 2010;42:751-4.
    • (2010) Nat Genet , vol.42 , pp. 751-754
    • Takata, R.1    Akamatsu, S.2    Kubo, M.3    Takahashi, A.4    Hosono, N.5    Kawaguchi, T.6
  • 22
    • 82755195732 scopus 로고    scopus 로고
    • New variants at 10q26 and 15q21 are associated with aggressive prostate cancer in a genome-wide association study from a prostate biopsy screening cohort
    • Nam RK, Zhang W, Siminovitch K, Shlien A, Kattan MW, Klotz LH, et al. New variants at 10q26 and 15q21 are associated with aggressive prostate cancer in a genome-wide association study from a prostate biopsy screening cohort. Cancer Biol Ther 2011;12:997-1004.
    • (2011) Cancer Biol Ther , vol.12 , pp. 997-1004
    • Nam, R.K.1    Zhang, W.2    Siminovitch, K.3    Shlien, A.4    Kattan, M.W.5    Klotz, L.H.6
  • 23
    • 70349545839 scopus 로고    scopus 로고
    • Identi fication of seven new prostate cancer susceptibility loci through a genome-wide association study
    • Eeles RA, Kote-Jarai Z, Al Olama AA, Giles GG, Guy M, Severi G, et al. Identi fication of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet 2009;41: 1116-21.
    • (2009) Nat Genet , vol.41 , pp. 1116-1121
    • Eeles, R.A.1    Kote-Jarai, Z.2    Al Olama, A.A.3    Giles, G.G.4    Guy, M.5    Severi, G.6
  • 28
  • 29
    • 53249103672 scopus 로고    scopus 로고
    • Association of prostate cancer risk variants with clinicopathologic characteristics of the disease
    • Xu J, Isaacs SD, Sun J, Li G, Wiley KE, Zhu Y, et al. Association of prostate cancer risk variants with clinicopathologic characteristics of the disease. Clin Cancer Res 2008;14:5819-24.
    • (2008) Clin Cancer Res , vol.14 , pp. 5819-5824
    • Xu, J.1    Isaacs, S.D.2    Sun, J.3    Li, G.4    Wiley, K.E.5    Zhu, Y.6
  • 30
    • 0036090508 scopus 로고    scopus 로고
    • Gleason score 7 prostate cancer on needle biopsy: Is the prognostic difference in gleason scores 4 3 and 3 4 independent of the number of involved cores?
    • Makarov DV, Sanderson H, Partin AW, Epstein JI. Gleason score 7 prostate cancer on needle biopsy: is the prognostic difference in Gleason scores 4 3 and 3 4 independent of the number of involved cores? J Urol 2002;167:2440-2.
    • (2002) J Urol , vol.167 , pp. 2440-2442
    • Makarov, D.V.1    Sanderson, H.2    Partin, A.W.3    Epstein, J.I.4
  • 31
    • 34548461739 scopus 로고    scopus 로고
    • Risk stratification of men with gleason score 7 to 10 tumors by primary and secondary gleason score: Results from the SEARCH database
    • Kang DE, Fitzsimons NJ, Presti JCJr, Kane CJ, Terris MK, Aronson WJ, et al. Risk stratification of men with Gleason score 7 to 10 tumors by primary and secondary Gleason score: results from the SEARCH database. Urology 2007;70:277-82.
    • (2007) Urology , vol.70 , pp. 277-282
    • Kang, D.E.1    Fitzsimons, N.J.2    Presti, J.C.3    Kane, C.J.4    Terris, M.K.5    Aronson, W.J.6
  • 32
    • 62649136510 scopus 로고    scopus 로고
    • Comparison of biochemical relapse-free survival between primary gleason score 3 and primary gleason score 4 for biopsy gleason score 7 prostate cancer
    • Burdick MJ, Reddy CA, Ulchaker J, Angermeier K, Altman A, Chehade N, et al. Comparison of biochemical relapse-free survival between primary Gleason score 3 and primary Gleason score 4 for biopsy Gleason score 7 prostate cancer. Int J Radiat Oncol Biol Phys 2009;73:1439-45.
    • (2009) Int J Radiat Oncol Biol Phys , vol.73 , pp. 1439-1445
    • Burdick, M.J.1    Reddy, C.A.2    Ulchaker, J.3    Angermeier, K.4    Altman, A.5    Chehade, N.6
  • 33
    • 79851513695 scopus 로고    scopus 로고
    • Predicting 15-year prostate cancer specific mortality after radical prostatectomy
    • Eggener SE, Scardino PT, Walsh PC, Han M, Partin AW, Trock BJ, et al. Predicting 15-year prostate cancer specific mortality after radical prostatectomy. J Urol 2011;185:869-75.
    • (2011) J Urol , vol.185 , pp. 869-875
    • Eggener, S.E.1    Scardino, P.T.2    Walsh, P.C.3    Han, M.4    Partin, A.W.5    Trock, B.J.6
  • 34
    • 35448976941 scopus 로고    scopus 로고
    • Tagging snps in the kallikrein genes 3 and 2 on 19q13 and their associations with prostate cancer in men of european origin
    • Pal P, Xi H, Sun G, Kaushal R, Meeks JJ, Thaxton CS, et al. Tagging SNPs in the kallikrein genes 3 and 2 on 19q13 and their associations with prostate cancer in men of European origin. Hum Genet 2007; 122:251-9.
    • (2007) Hum Genet , vol.122 , pp. 251-259
    • Pal, P.1    Xi, H.2    Sun, G.3    Kaushal, R.4    Meeks, J.J.5    Thaxton, C.S.6
  • 35
    • 0042594668 scopus 로고    scopus 로고
    • Association between genetic polymorphisms in the prostate-specific antigen gene promoter and serum prostate-specific antigen levels
    • Cramer SD, Chang BL, Rao A, Hawkins GA, Zheng SL, Wade WN, et al. Association between genetic polymorphisms in the prostate-specific antigen gene promoter and serum prostate-specific antigen levels. J Natl Cancer Inst 2003;95:1044-53.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1044-1053
    • Cramer, S.D.1    Chang, B.L.2    Rao, A.3    Hawkins, G.A.4    Zheng, S.L.5    Wade, W.N.6
  • 36
    • 77952026425 scopus 로고    scopus 로고
    • Blood biomarker levels to aid discovery of cancer-related singlenucleotide polymorphisms: Kallikreins and prostate cancer
    • Klein RJ, Hallden C, Cronin AM, Ploner A, Wiklund F, Bjartell AS, et al. Blood biomarker levels to aid discovery of cancer-related singlenucleotide polymorphisms: kallikreins and prostate cancer. Cancer Prev Res 2010;3:611-9.
    • (2010) Cancer Prev Res , vol.3 , pp. 611-619
    • Klein, R.J.1    Hallden, C.2    Cronin, A.M.3    Ploner, A.4    Wiklund, F.5    Bjartell, A.S.6
  • 37
  • 39
    • 33751504915 scopus 로고    scopus 로고
    • The signifi cance of modified gleason grading of prostatic carcinoma in biopsy and radical prostatectomy specimens
    • Helpap B, Egevad L. The signifi cance of modified Gleason grading of prostatic carcinoma in biopsy and radical prostatectomy specimens. Virchows Arch 2006;449:622-7.
    • (2006) Virchows Arch , vol.449 , pp. 622-627
    • Helpap, B.1    Egevad, L.2
  • 40
    • 46449138576 scopus 로고    scopus 로고
    • The impact of the 2005 international society of urological pathology consensus conference on standard gleason grading of prostatic carcinoma in needle biopsies
    • Billis A, Guimaraes MS, Freitas LL, Meirelles L, Magna LA, Ferreira U. The impact of the 2005 International Society Of Urological Pathology Consensus Conference on standard Gleason grading of prostatic carcinoma in needle biopsies. J Urol 2008;180:548-52.
    • (2008) J Urol , vol.180 , pp. 548-552
    • Billis, A.1    Guimaraes, M.S.2    Freitas, L.L.3    Meirelles, L.4    Magna, L.A.5    Ferreira, U.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.