Clinical effects of vitamin D in children with asthma

International Archives of Allergy and Immunology

Volumn 164, Issue 4, 2014, Pages 319-325

  Dogru, Mahmut ^a   Kirmizibekmez, Heves ^a   Mutlu, Rahime Gul Yesiltepe ^a   Aktas, Alev ^a   Ozturkmen, Seda ^a  

^a Zeynep Kamil Obstetric and Pediatric Diseases Training and Research Hospital   (Turkey)

Author keywords

Asthma; Child; Severity; Vitamin D

Indexed keywords

ALLERGEN; CALCIFEDIOL; GLUCOCORTICOID; IMMUNOGLOBULIN E; 25-HYDROXYVITAMIN D; BIOLOGICAL MARKER; VITAMIN D;

ALLERGIC ASTHMA; ARTICLE; ASTHMA; CHILD; CONTROLLED STUDY; DEMOGRAPHY; DISEASE DURATION; DISEASE EXACERBATION; DISEASE SEVERITY; EOSINOPHIL COUNT; FEMALE; FOLLOW UP; HOSPITALIZATION; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PRICK TEST; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; WHEEZING; ANALOGS AND DERIVATIVES; BLOOD; CASE CONTROL STUDY; COMPLICATION; DISEASE COURSE; EOSINOPHIL; IMMUNOLOGY; LEUKOCYTE COUNT; METABOLISM; PRESCHOOL CHILD; SEVERITY OF ILLNESS INDEX;

ASTHMA; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; DISEASE PROGRESSION; EOSINOPHILS; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOGLOBULIN E; LEUKOCYTE COUNT; MALE; SEVERITY OF ILLNESS INDEX; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84908571410     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000366279     Document Type: Article

References (25)

1. Bateman ED, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, FitzGerald M, Gibson P, Ohta K, O'Byrne P, Pedersen SE, Pizzichini E, Sullivan SD, Wenzel SE, Zar HJ: Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008; 31: 143-178.
2. Searing DA, Leung DY: Vitamin D in atopic dermatitis, asthma and allergic diseases Immunol Allergy Clin North Am 2010; 30: 397-409.
3. Litonjua AA, Weiss ST: Is vitamin D deficiency to blame for the asthma epidemic? J Allergy Clin Immunol 2007; 120: 1031-1035.
4. Dimeloe S, Nanzer A, Ryanna K, Hawrylowicz C: Regulatory T cells, inflammation and the allergic response: the role of glucocorticoids and vitamin D. J Steroid Biochem Mol Biol 2010; 120: 86-95.
5. Bener A, Ehlayel MS, Tulic MK, Hamid Q: Vitamin D deficiency as a strong predictor of asthma in children. Int Arch Allergy Immunol 2012; 157: 168-175.
6. Uysalol M, Mutlu LC, Saracoglu GV, Karasu E, Guzel S, Kayaoglu S, Uzel N: Childhood asthma and vitamin D deficiency in Turkey: is there cause and effect relationship between them? Ital J Pediatr 2013; 39: 78-86.
7. Alyasin S, Momen T, Kashef S, Alipour A, Amin R: The relationship between serum 25 hydroxy vitamin D levels and asthma in children. Allergy Asthma Immunol Res 2011; 3: 251-255.
8. Brehm JM, Acosta-Pérez E, Klei L, Roeder K, Barmada M, Boutaoui N, et al: Vitamin D insufficiency and severe asthma exacerbations in Puerto Rican children. Am J Respir Crit Care Med 2012; 186: 140-146.
9. Gergen PJ, Teach SJ, Mitchell HE, Freishtat RF, Calatroni A, Matsui E, et al: Lack of a relation between serum 25-hydroxyvitamin D concentrations and asthma in adolescents. Am J Clin Nutr 2013; 97: 1228-1234.
10. Cheng HM, Kim S, Park GH, Chang SE, Bang S, Won CH, Lee MW, Choi JH, Moon KC: Low vitamin D levels are associated with atopic dermatitis, but not allergic rhinitis, asthma, or IgE sensitization, in the adult Korean population. J Allergy Clin Immunol 2014; 133: 1048-1055.
11. Mai XM, Langhammer A, Camargo CA Jr, Chen Y: Serum 25-hydroxyvitamin D levels and incident asthma in adults: the HUNT Study. Am J Epidemiol 2012; 176: 1169-1176.
12. Korn S, Hübner M, Jung M, Blettner M, Buhl R: Severe and uncontrolled adult asthma is associated with vitamin D insufficiency and deficiency. Respir Res 2013; 14: 25.
13. Brehm JM, Schuemann B, Fuhlbrigge AL, Hollis BW, Strunk RC, Zeiger RS, Weiss ST, Litonjua AA; Childhood Asthma Management Program Research Group: Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study. J Allergy Clin Immunol 2010; 126: 52-58.
14. Montero-Arias F, Sedó-MejѤa G, Ramos-Esquivel A: Vitamin D insufficiency and asthma severity in adults from Costa Rica. Allergy Asthma Immunol Res 2013; 5: 283-288.
15. Searing DA, Zhang Y, Murphy JR, Hauk PJ, Goleva E, Leung DY: Decreased serum vitamin levels in children with asthma are associated with increased corticosteroid use. J Allergy Clin Immunol 2010; 125: 995-1000.
16. Krobtrakulchai W, Praikanahok J, Visitsunthorn N, Vichyanond P, Manonukul K, Pratumvinit B, Jirapongsananuruk O: The effect of vitamin D status on pediatric asthma at a university hospital, Thailand. Allergy Asthma Immunol Res 2013; 5: 289-294.
17. Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher JC, Gallo RL, Jones G, et al: The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab 2011; 96: 53-58.
18. Institute of Medicine: Dietary Reference Intakes for Calcium and Vitamin D. Washington, Institute of Medicine, 2010.
19. Prietl B, Treiber G, Pieber TR, Amrein K: Vitamin D and immune function. Nutrients 2013; 5: 2502-2521.
20. Yim S, Dhawan P, Ragunath C, Christakos S, Diamond G: Induction of cathelicidin in normal and CF bronchial epithelial cells by 1,25-dihydroxyvitamin D 3 . J Cyst Fibros 2007; 6: 403-410.
21. Liu PT, Stenger S, Tang DH, Modlin RL: Cutting edge: vitamin D-mediated human antimicrobial activity against Mycobacterium tuberculosis is dependent on the induction of cathelicidin. J Immunol 2007; 179: 2060-2063.
22. Hansdottir S, Monick MM, Lovan N, Powers L, Gerke A, Hunninghake GW: Vitamin D decreases respiratory syncytial virus induction of NF-κB-linked chemokines and cytokines in airway epithelium while maintaining the antiviral state. J Immunol 2010; 184: 965-974.
23. Ginde AA, Mansbach JM, Camargo CA Jr: Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the third National Health and Nutrition Examination Survey. Arch Intern Med 2009; 169: 384-390.
24. Hypponen E, Sovio U, Wjst M, Patel S, Pekkanen J, Hartikainen AL, et al: Infant vitamin D supplementation and allergic conditions in adulthood: northern Finland birth cohort 1966. Ann NY Acad Sci 2004; 1037: 84-95.
25. Hollams EM, Hart PH, Holt BJ, Serralha M, Parsons F, de Klerk NH, Zhang G, Sly PD, Holt PG: Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort study. Eur Respir J 2011; 38: 1320-1327.