메뉴 건너뛰기




Volumn 127, Issue , 2014, Pages 15-20

Sexually dimorphic dopaminergic dysfunction in a transgenic mouse model of Huntington's disease

Author keywords

Bupropion; Dopamine; Huntington's disease; Locomotor activity; Sex differences; Tandem repeat disorder

Indexed keywords

6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; AMFEBUTAMONE; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE TRANSPORTER; 3,4-DIHYDROXYPHENYLACETIC ACID; DOPAMINE UPTAKE INHIBITORS; RECEPTORS, DOPAMINE D1;

EID: 84908553434     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2014.10.004     Document Type: Article
Times cited : (10)

References (40)
  • 1
    • 84867573354 scopus 로고    scopus 로고
    • Greater striatal dopamine transporter density may be associated with major depressive episode
    • Amsterdam JD, Newberg AB, Soeller I, Shults J. Greater striatal dopamine transporter density may be associated with major depressive episode. J Affect Disord 2012;141:425-31.
    • (2012) J Affect Disord , vol.141 , pp. 425-431
    • Amsterdam, J.D.1    Newberg, A.B.2    Soeller, I.3    Shults, J.4
  • 3
    • 77955466233 scopus 로고    scopus 로고
    • Environmental enrichment reduces neuronal intranuclear inclusion load but has no effect on messenger RNA expression in a mouse model of Huntington disease
    • Benn CL, Luthi-Carter R, Kuhn A, Sadri-Vakili G, Blankson KL, Dalai SC, et al. Environmental enrichment reduces neuronal intranuclear inclusion load but has no effect on messenger RNA expression in a mouse model of Huntington disease. J Neuropathol Exp Neurol 2010;69:817-27.
    • (2010) J Neuropathol Exp Neurol , vol.69 , pp. 817-827
    • Benn, C.L.1    Luthi-Carter, R.2    Kuhn, A.3    Sadri-Vakili, G.4    Blankson, K.L.5    Dalai, S.C.6
  • 5
    • 33745210300 scopus 로고    scopus 로고
    • Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease
    • Bjorkqvist M, Petersen A, Bacos K, Isaacs J, Norlen P, Gil J, et al. Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease. Hum Mol Genet 2006;15:1713-21.
    • (2006) Hum Mol Genet , vol.15 , pp. 1713-1721
    • Bjorkqvist, M.1    Petersen, A.2    Bacos, K.3    Isaacs, J.4    Norlen, P.5    Gil, J.6
  • 6
    • 49649121318 scopus 로고    scopus 로고
    • Sex differences in a transgenic rat model of Huntington's disease: Decreased 17beta-estradiol levels correlate with reduced numbers of DARPP32+ neurons in males
    • Bode FJ, Stephan M, Suhling H, Pabst R, Straub RH, Raber KA, et al. Sex differences in a transgenic rat model of Huntington's disease: decreased 17beta-estradiol levels correlate with reduced numbers of DARPP32+ neurons in males. Hum Mol Genet 2008;17:2595-609.
    • (2008) Hum Mol Genet , vol.17 , pp. 2595-2609
    • Bode, F.J.1    Stephan, M.2    Suhling, H.3    Pabst, R.4    Straub, R.H.5    Raber, K.A.6
  • 7
    • 0032568517 scopus 로고    scopus 로고
    • Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human Huntington disease gene
    • Cha JH, Kosinski CM, Kerner JA, Alsdorf SA, Mangiarini L, Davies SW, et al. Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human Huntington disease gene. Proc Natl Acad Sci U S A 1998;95:6480-5.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 6480-6485
    • Cha, J.H.1    Kosinski, C.M.2    Kerner, J.A.3    Alsdorf, S.A.4    Mangiarini, L.5    Davies, S.W.6
  • 8
    • 33749009774 scopus 로고    scopus 로고
    • Aberrant cortical synaptic plasticity and dopaminergic dysfunction in a mouse model of Huntington's disease
    • Cummings DM, Milnerwood AJ, Dallerac GM, Waights V, Brown JY, Vatsavayai SC, et al. Aberrant cortical synaptic plasticity and dopaminergic dysfunction in a mouse model of Huntington's disease. Hum Mol Genet 2006;15:2856-68.
    • (2006) Hum Mol Genet , vol.15 , pp. 2856-2868
    • Cummings, D.M.1    Milnerwood, A.J.2    Dallerac, G.M.3    Waights, V.4    Brown, J.Y.5    Vatsavayai, S.C.6
  • 9
    • 79955826768 scopus 로고    scopus 로고
    • Impaired long-term potentiation in the prefrontal cortex of Huntington's disease mouse models: Rescue by D1 dopamine receptor activation
    • Dallerac GM, Vatsavayai SC, Cummings DM, Milnerwood AJ, Peddie CJ, Evans KA, et al. Impaired long-term potentiation in the prefrontal cortex of Huntington's disease mouse models: rescue by D1 dopamine receptor activation. Neurodegener Dis 2011;8:230-9.
    • (2011) Neurodegener Dis , vol.8 , pp. 230-239
    • Dallerac, G.M.1    Vatsavayai, S.C.2    Cummings, D.M.3    Milnerwood, A.J.4    Peddie, C.J.5    Evans, K.A.6
  • 10
    • 68349152770 scopus 로고    scopus 로고
    • Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease
    • Dowie MJ, Bradshaw HB, Howard ML, Nicholson LF, Faull RL, Hannan AJ, et al. Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. Neuroscience 2009;163:456-65.
    • (2009) Neuroscience , vol.163 , pp. 456-465
    • Dowie, M.J.1    Bradshaw, H.B.2    Howard, M.L.3    Nicholson, L.F.4    Faull, R.L.5    Hannan, A.J.6
  • 11
    • 60049097209 scopus 로고    scopus 로고
    • Sex differences in corticolimbic dopamine and serotonin systems in the rat and the effect of postnatal handling
    • Duchesne A, Dufresne MM, Sullivan RM. Sex differences in corticolimbic dopamine and serotonin systems in the rat and the effect of postnatal handling. Prog Neuropsychopharmacol Biol Psychiatry 2009;33:251-61.
    • (2009) Prog Neuropsychopharmacol Biol Psychiatry , vol.33 , pp. 251-261
    • Duchesne, A.1    Dufresne, M.M.2    Sullivan, R.M.3
  • 12
    • 0030897476 scopus 로고    scopus 로고
    • PET study of the preand post-synaptic dopaminergic markers for the neurodegenerative process in Huntington's disease
    • Ginovart N, Lundin A, Farde L, Halldin C, Backman L, Swahn CG, et al. PET study of the preand post-synaptic dopaminergic markers for the neurodegenerative process in Huntington's disease. Brain 1997;120(Pt 3):503-14.
    • (1997) Brain , vol.120 , pp. 503-514
    • Ginovart, N.1    Lundin, A.2    Farde, L.3    Halldin, C.4    Backman, L.5    Swahn, C.G.6
  • 13
    • 0345118102 scopus 로고    scopus 로고
    • Delayed onset of Huntington's disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptors
    • Glass M, van Dellen A, Blakemore C, Hannan AJ, Faull RL. Delayed onset of Huntington's disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptors. Neuroscience 2004;123:207-12.
    • (2004) Neuroscience , vol.123 , pp. 207-212
    • Glass, M.1    Van Dellen, A.2    Blakemore, C.3    Hannan, A.J.4    Faull, R.L.5
  • 14
    • 27644524469 scopus 로고    scopus 로고
    • Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine
    • Grote HE, Bull ND, Howard ML, van Dellen A, Blakemore C, Bartlett PF, et al. Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine. Eur J Neurosci 2005;22:2081-8.
    • (2005) Eur J Neurosci , vol.22 , pp. 2081-2088
    • Grote, H.E.1    Bull, N.D.2    Howard, M.L.3    Van Dellen, A.4    Blakemore, C.5    Bartlett, P.F.6
  • 15
    • 84872831352 scopus 로고    scopus 로고
    • The interaction between dopamine transporter function, gender differences, and possible laterality in depression
    • Hsiao MC, Lin KJ, Liu CY, Schatz DB. The interaction between dopamine transporter function, gender differences, and possible laterality in depression. Psychiatry Res 2013;211:72-7.
    • (2013) Psychiatry Res , vol.211 , pp. 72-77
    • Hsiao, M.C.1    Lin, K.J.2    Liu, C.Y.3    Schatz, D.B.4
  • 16
    • 33645868624 scopus 로고    scopus 로고
    • Dopamine release is severely compromised in the R6/2 mouse model of Huntington's disease
    • Johnson MA, Rajan V, Miller CE, Wightman RM. Dopamine release is severely compromised in the R6/2 mouse model of Huntington's disease. J Neurochem 2006;97:737-46.
    • (2006) J Neurochem , vol.97 , pp. 737-746
    • Johnson, M.A.1    Rajan, V.2    Miller, C.E.3    Wightman, R.M.4
  • 18
    • 84903629783 scopus 로고    scopus 로고
    • High stress hormone levels accelerate the onset of memory deficits in male Huntington's disease mice
    • Mo C, Pang TY, Ransome MI, Hill RA, Renoir T, Hannan AJ. High stress hormone levels accelerate the onset of memory deficits in male Huntington's disease mice. Neurobiol Dis 2014;69:248-62.
    • (2014) Neurobiol Dis , vol.69 , pp. 248-262
    • Mo, C.1    Pang, T.Y.2    Ransome, M.I.3    Hill, R.A.4    Renoir, T.5    Hannan, A.J.6
  • 19
    • 79953671359 scopus 로고    scopus 로고
    • Altered dopamine and serotonin metabolism in motorically asymptomatic R6/2 mice
    • Mochel F, Durant B, Durr A, Schiffmann R. Altered dopamine and serotonin metabolism in motorically asymptomatic R6/2 mice. PLoS One 2011;6:e18336.
    • (2011) PLoS One , vol.6 , pp. e18336
    • Mochel, F.1    Durant, B.2    Durr, A.3    Schiffmann, R.4
  • 20
    • 79952004099 scopus 로고    scopus 로고
    • Impaired dopamine release and uptake in R6/1 Huntington's disease model mice
    • Ortiz AN, Kurth BJ, Osterhaus GL, Johnson MA. Impaired dopamine release and uptake in R6/1 Huntington's disease model mice. Neurosci Lett 2011;492:11-4.
    • (2011) Neurosci Lett , vol.492 , pp. 11-14
    • Ortiz, A.N.1    Kurth, B.J.2    Osterhaus, G.L.3    Johnson, M.A.4
  • 21
    • 84863405511 scopus 로고    scopus 로고
    • Motor function and dopamine release measurements in transgenic Huntington's disease model rats
    • Ortiz AN, Osterhaus GL, Lauderdale K, Mahoney L, Fowler SC, von Horsten S, et al. Motor function and dopamine release measurements in transgenic Huntington's disease model rats. Brain Res 2012;1450:148-56.
    • (2012) Brain Res , vol.1450 , pp. 148-156
    • Ortiz, A.N.1    Osterhaus, G.L.2    Lauderdale, K.3    Mahoney, L.4    Fowler, S.C.5    Von Horsten, S.6
  • 22
    • 84855302313 scopus 로고    scopus 로고
    • Huntington's disease knock-inmalemice show specific anxiety-like behaviour and altered neuronal maturation
    • Orvoen S, Pla P, Gardier AM, Saudou F, David DJ. Huntington's disease knock-inmalemice show specific anxiety-like behaviour and altered neuronal maturation. Neurosci Lett 2012;507:127-32.
    • (2012) Neurosci Lett , vol.507 , pp. 127-132
    • Orvoen, S.1    Pla, P.2    Gardier, A.M.3    Saudou, F.4    David, D.J.5
  • 23
    • 58949085531 scopus 로고    scopus 로고
    • Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease
    • Pang TY, Du X, Zajac MS, Howard ML, Hannan AJ. Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease. Hum Mol Genet 2009;18:753-66.
    • (2009) Hum Mol Genet , vol.18 , pp. 753-766
    • Pang, T.Y.1    Du, X.2    Zajac, M.S.3    Howard, M.L.4    Hannan, A.J.5
  • 24
    • 73049110382 scopus 로고    scopus 로고
    • Cortical dopamine dysfunction in symptomatic and premanifest Huntington's disease gene carriers
    • Pavese N, Politis M, Tai YF, Barker RA, Tabrizi SJ, Mason SL, et al. Cortical dopamine dysfunction in symptomatic and premanifest Huntington's disease gene carriers. Neurobiol Dis 2010;37:356-61.
    • (2010) Neurobiol Dis , vol.37 , pp. 356-361
    • Pavese, N.1    Politis, M.2    Tai, Y.F.3    Barker, R.A.4    Tabrizi, S.J.5    Mason, S.L.6
  • 25
    • 0036453663 scopus 로고    scopus 로고
    • Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice
    • Petersen A, Puschban Z, Lotharius J, NicNiocaill B, Wiekop P, O'Connor WT, et al. Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice. Neurobiol Dis 2002;11:134-46.
    • (2002) Neurobiol Dis , vol.11 , pp. 134-146
    • Petersen, A.1    Puschban, Z.2    Lotharius, J.3    NicNiocaill, B.4    Wiekop, P.5    O'Connor, W.T.6
  • 26
    • 84899154969 scopus 로고    scopus 로고
    • Mood disorders in Huntington's disease: Frombehavior to cellular andmolecular mechanisms
    • Pla P, Orvoen S, Saudou F, David DJ, Humbert S. Mood disorders in Huntington's disease: frombehavior to cellular andmolecular mechanisms. Front Behav Neurosci 2014;8:135.
    • (2014) Front Behav Neurosci , vol.8 , pp. 135
    • Pla, P.1    Orvoen, S.2    Saudou, F.3    David, D.J.4    Humbert, S.5
  • 27
    • 84860483495 scopus 로고    scopus 로고
    • Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice
    • Pouladi MA, Stanek LM, Xie Y, Franciosi S, Southwell AL, Deng Y, et al. Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice. Hum Mol Genet 2012;21:2219-32.
    • (2012) Hum Mol Genet , vol.21 , pp. 2219-2232
    • Pouladi, M.A.1    Stanek, L.M.2    Xie, Y.3    Franciosi, S.4    Southwell, A.L.5    Deng, Y.6
  • 28
    • 84884537922 scopus 로고    scopus 로고
    • Choosing an animal model for the study of Huntington's disease
    • Pouladi MA, Morton AJ, Hayden MR. Choosing an animal model for the study of Huntington's disease. Nat Rev Neurosci 2013;14:708-21.
    • (2013) Nat Rev Neurosci , vol.14 , pp. 708-721
    • Pouladi, M.A.1    Morton, A.J.2    Hayden, M.R.3
  • 29
    • 79960098807 scopus 로고    scopus 로고
    • Sexually dimorphic serotonergic dysfunction in a mouse model of Huntington's disease and depression
    • Renoir T, Zajac MS, Du X, Pang TY, Leang L, Chevarin C, et al. Sexually dimorphic serotonergic dysfunction in a mouse model of Huntington's disease and depression. PLoS One 2011;6:e22133.
    • (2011) PLoS One , vol.6 , pp. e22133
    • Renoir, T.1    Zajac, M.S.2    Du, X.3    Pang, T.Y.4    Leang, L.5    Chevarin, C.6
  • 30
    • 84857066193 scopus 로고    scopus 로고
    • Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise
    • Renoir T, Pang TY, Zajac MS, Chan G, Du X, Leang L, et al. Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise. Br J Pharmacol 2012;165:1375-89.
    • (2012) Br J Pharmacol , vol.165 , pp. 1375-1389
    • Renoir, T.1    Pang, T.Y.2    Zajac, M.S.3    Chan, G.4    Du, X.5    Leang, L.6
  • 32
    • 0037097287 scopus 로고    scopus 로고
    • Differential D1 and D2 receptor-mediated effects on immediate early gene induction in a transgenic mouse model of Huntington's disease
    • Spektor BS, Miller DW, Hollingsworth ZR, Kaneko YA, Solano SM, Johnson JM, et al. Differential D1 and D2 receptor-mediated effects on immediate early gene induction in a transgenic mouse model of Huntington's disease. Brain Res Mol Brain Res 2002; 102:118-28.
    • (2002) Brain Res Mol Brain Res , vol.102 , pp. 118-128
    • Spektor, B.S.1    Miller, D.W.2    Hollingsworth, Z.R.3    Kaneko, Y.A.4    Solano, S.M.5    Johnson, J.M.6
  • 33
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • The Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993;72:971-83.
    • (1993) Cell , vol.72 , pp. 971-983
  • 34
    • 0030839306 scopus 로고    scopus 로고
    • Modulation of mesolimbic dopaminergic activity over the rat estrous cycle
    • Thompson TL1, Moss RL. Modulation of mesolimbic dopaminergic activity over the rat estrous cycle. Neurosci Lett 1997;229:145-8.
    • (1997) Neurosci Lett , vol.229 , pp. 145-148
    • Thompson, T.L.1    Moss, R.L.2
  • 35
    • 80054113970 scopus 로고    scopus 로고
    • Psychomotor stimulation by dopamine D(1)-like but not D(2)-like agonists in most mouse strains
    • Thomsen M, Ralph RJ, Caine SB. Psychomotor stimulation by dopamine D(1)-like but not D(2)-like agonists in most mouse strains. Exp Clin Psychopharmacol 2011;19:342-60.
    • (2011) Exp Clin Psychopharmacol , vol.19 , pp. 342-360
    • Thomsen, M.1    Ralph, R.J.2    Caine, S.B.3
  • 37
    • 84873730617 scopus 로고    scopus 로고
    • Sex differences in novelty- and psychostimulant-induced behaviors of C57BL/6 mice
    • Van Swearingen AE, Walker QD, Kuhn CM. Sex differences in novelty- and psychostimulant-induced behaviors of C57BL/6 mice. Psychopharmacology (Berl) 2013;225:707-18.
    • (2013) Psychopharmacology (Berl) , vol.225 , pp. 707-718
    • Van Swearingen, A.E.1    Walker, Q.D.2    Kuhn, C.M.3
  • 38
    • 15844374819 scopus 로고    scopus 로고
    • Striatal dopamine transporter imaging correlates with anxiety and depression symptoms in Parkinson's disease
    • Weintraub D, Newberg AB, Cary MS, Siderowf AD, Moberg PJ, Kleiner-Fisman G, et al. Striatal dopamine transporter imaging correlates with anxiety and depression symptoms in Parkinson's disease. J Nucl Med 2005;46:227-32.
    • (2005) J Nucl Med , vol.46 , pp. 227-232
    • Weintraub, D.1    Newberg, A.B.2    Cary, M.S.3    Siderowf, A.D.4    Moberg, P.J.5    Kleiner-Fisman, G.6
  • 39
    • 0142153442 scopus 로고    scopus 로고
    • Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology
    • Yohrling GJ, Jiang GC, DeJohn MM, Miller DW, Young AB, Vrana KE, et al. Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology. Brain Res Mol Brain Res 2003; 119:28-36.
    • (2003) Brain Res Mol Brain Res , vol.119 , pp. 28-36
    • Yohrling, G.J.1    Jiang, G.C.2    DeJohn, M.M.3    Miller, D.W.4    Young, A.B.5    Vrana, K.E.6
  • 40
    • 0034027027 scopus 로고    scopus 로고
    • Sexual differences and estrous cycle in methamphetamine-induced dopamine and serotonin depletions in the striatum of mice
    • Yu L, Liao PC. Sexual differences and estrous cycle in methamphetamine-induced dopamine and serotonin depletions in the striatum of mice. J Neural Transm 2000;107: 419-27.
    • (2000) J Neural Transm , vol.107 , pp. 419-427
    • Yu, L.1    Liao, P.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.