Controlled reoxygenation during cardiopulmonary bypass decreases markers of organ damage, inflammation, and oxidative stress in single-ventricle patients undergoing pediatric heart surgery

Journal of Thoracic and Cardiovascular Surgery

Volumn 148, Issue 3, 2014, Pages 792-801.e8

  Caputo, Massimo ^a,b   Mokhtari, Amir ^c   Miceli, Antonio ^c   Ghorbel, Mohamed T ^c   Angelini, Gianni D ^c   Parry, Andrew J ^b   Suleiman, Saadeh M ^c  

^a BRISTOL ROYAL HOSPITAL FOR CHILDREN   (United Kingdom)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; OXYGEN; TROPONIN I;

BRAIN INJURY; CARDIOPULMONARY BYPASS; CHILD; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED REOXYGENATION; CONTROLLED STUDY; FEMALE; HEART INJURY; HEART SINGLE VENTRICLE; HEART SURGERY; HUMAN; INFLAMMATION; LIVER INJURY; MALE; ORGAN INJURY; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PEDIATRIC SURGERY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REOXYGENATION; SAMPLE SIZE;

AGE FACTORS; BIOLOGICAL MARKERS; CARDIAC SURGICAL PROCEDURES; CARDIOPULMONARY BYPASS; CHILD; CHILD, PRESCHOOL; DINOPROST; ENGLAND; FEMALE; HEART DEFECTS, CONGENITAL; HEART VENTRICLES; HUMANS; INFANT; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; OXIDATIVE STRESS; OXYGEN INHALATION THERAPY; PARTIAL PRESSURE; TIME FACTORS; TREATMENT OUTCOME; TROPONIN;

EID: 84908503392     PISSN: 00225223     EISSN: 1097685X     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2014.06.001     Document Type: Conference Paper

References (28)

1. C. Goldberg Neurocognitive outcomes for children with functional single ventricle malformations Pediatr Cardiol 28 2007 443 447
2. J. Butler, V.L. Pathi, R.D. Paton, R.W. Logan, K.J. MacArthur, and M.P. Jamieson et al. Acute-phase responses to cardiopulmonary bypass in children weighing less than 10 kilograms Ann Thorac Surg 62 1996 538 542
3. P.J. Curi-Curi, J. Cervantes-Salazar, J. Calderon-Colmenero, J.A. Garcia-Montes, and S. Ramirez [Operative results in cardiovascular surgery of the neonate] Rev Invest Clin 64 2012 199 206
4. M.C. Morris, R.F. Ittenbach, R.I. Godinez, J.D. Portnoy, S. Tabbutt, and B.D. Hanna et al. Risk factors for mortality in 137 pediatric cardiac intensive care unit patients managed with extracorporeal membrane oxygenation Crit Care Med 32 2004 1061 1069
5. P. Modi, H. Imura, M. Caputo, A. Pawade, A. Parry, and G.D. Angelini et al. Cardiopulmonary bypass-induced myocardial reoxygenation injury in pediatric patients with cyanosis J Thorac Cardiovasc Surg 124 2002 1035 1036
6. P.J. del Nido, L.N. Benson, D.A. Mickle, S. Kielmanowicz, J.G. Coles, and G.J. Wilson Impaired left ventricular postischemic function and metabolism in chronic right ventricular hypertrophy Circulation 76 1987 V168 V173
7. P.J. del Nido, D.A. Mickle, G.J. Wilson, L.N. Benson, R.D. Weisel, and J.G. Coles et al. Inadequate myocardial protection with cold cardioplegic arrest during repair of tetralogy of Fallot J Thorac Cardiovasc Surg 95 1988 223 229
8. 2 Eur J Cardiothorac Surg 9 1995 410 418
9. K. Ihnken, K. Morita, and G.D. Buckberg Delayed cardioplegic reoxygenation reduces reoxygenation injury in cyanotic immature hearts Ann Thorac Surg 66 1998 177 182
10. K. Ihnken, A. Winkler, C. Schlensak, K. Sarai, G. Neidhart, and U. Unkelbach et al. Normoxic cardiopulmonary bypass reduces oxidative myocardial damage and nitric oxide during cardiac operations in the adult J Thorac Cardiovasc Surg 116 1998 327 334
11. M. Caputo, A. Mokhtari, C.A. Rogers, N. Panayiotou, Q. Chen, and M.T. Ghorbel et al. The effects of normoxic versus hyperoxic cardiopulmonary bypass on oxidative stress and inflammatory response in cyanotic pediatric patients undergoing open cardiac surgery: a randomized controlled trial J Thorac Cardiovasc Surg 138 2009 206 214
12. P. Modi, M.S. Suleiman, B. Reeves, A. Pawade, A.J. Parry, and G.D. Angelini et al. Myocardial metabolic changes during pediatric cardiac surgery: a randomized study of 3 cardioplegic techniques J Thorac Cardiovasc Surg 128 2004 67 75
13. H. Imura, M. Caputo, A. Parry, A. Pawade, G.D. Angelini, and M.S. Suleiman Age-dependent and hypoxia-related differences in myocardial protection during pediatric open heart surgery Circulation 103 2001 1551 1556
14. L.A. Bruns, M.K. Chrisant, J.M. Lamour, R.E. Shaddy, E. Pahl, and E.D. Blume et al. Carvedilol as therapy in pediatric heart failure: an initial multicenter experience J Pediatr 138 2001 505 511
15. M.S. Suleiman, K. Zacharowski, and G.D. Angelini Inflammatory response and cardioprotection during open-heart surgery: the importance of anaesthetics Br J Pharmacol 153 2008 21 33
16. E. Albers, B.S. Donahue, G. Milne, B.R. Saville, W. Wang, and D. Bichell et al. Perioperative plasma f(2)-isoprostane levels correlate with markers of impaired ventilation in infants with single-ventricle physiology undergoing stage 2 surgical palliation on the cardiopulmonary bypass Pediatr Cardiol 33 2012 562 568
17. S. Christen, B. Finckh, J. Lykkesfeldt, P. Gessler, M. Frese-Schaper, and P. Nielsen et al. Oxidative stress precedes peak systemic inflammatory response in pediatric patients undergoing cardiopulmonary bypass operation Free Radic Biol Med 38 2005 1323 1332
18. J. Bocsi, J. Hambsch, P. Osmancik, P. Schneider, G. Valet, and A. Tarnok Preoperative prediction of pediatric patients with effusions and edema following cardiopulmonary bypass surgery by serological and routine laboratory data Crit Care 6 2002 226 233
19. A.B. Madhok, K. Ojamaa, V. Haridas, V.A. Parnell, S. Pahwa, and D. Chowdhury Cytokine response in children undergoing surgery for congenital heart disease Pediatr Cardiol 27 2006 408 413
20. C.K. Allan, J.W. Newburger, E. McGrath, J. Elder, C. Psoinos, and P.C. Laussen et al. The relationship between inflammatory activation and clinical outcome after infant cardiopulmonary bypass Anesth Analg 111 2010 1244 1251
21. P. Gessler, V. Hohl, T. Carrel, J. Pfenninger, E.R. Schmid, and O. Baenziger et al. Administration of steroids in pediatric cardiac surgery: impact on clinical outcome and systemic inflammatory response Pediatr Cardiol 26 2005 595 600
22. H.T. de Mendonca-Filho, R.V. Gomes, L.A. de Almeida Campos, B. Tura, E.M. Nunes, and R. Gomes et al. Circulating levels of macrophage migration inhibitory factor are associated with mild pulmonary dysfunction after cardiopulmonary bypass Shock 22 2004 533 537
23. F.A. Bozza, R.N. Gomes, A.M. Japiassu, M. Soares, H.C. Castro-Faria-Neto, and P.T. Bozza et al. Macrophage migration inhibitory factor levels correlate with fatal outcome in sepsis Shock 22 2004 309 313
24. X. Lin, H. Yang, T. Sakuragi, M. Hu, L.L. Mantell, and S. Hayashi et al. Alpha-chemokine receptor blockade reduces high mobility group box 1 protein-induced lung inflammation and injury and improves survival in sepsis Am J Physiol Lung Cell Mol Physiol 289 2005 L583 L590
25. J. Fukuzawa, J. Nishihira, N. Hasebe, T. Haneda, J. Osaki, and T. Saito et al. Contribution of macrophage migration inhibitory factor to extracellular signal-regulated kinase activation by oxidative stress in cardiomyocytes J Biol Chem 277 2002 24889 24895
26. S. Preau, D. Montaigne, T. Modine, G. Fayad, M. Koussa, and M. Tardivel et al. Macrophage migration inhibitory factor induces contractile and mitochondria dysfunction by altering cytoskeleton network in the human heart* Crit Care Med 41 2013 e125 e133
27. P.A. Grace, and R.T. Mathie Ischaemia-Reperfusion Injury 1999 Blackwell Science Oxford
28. L.B. Ware, and M.A. Matthay The acute respiratory distress syndrome N Engl J Med 342 2000 1334 1349