N-diethylnitrosamine mouse hepatotoxicity: Time-related effects on histology and oxidative stress

Experimental and Toxicologic Pathology

Volumn 66, Issue 9-10, 2014, Pages 429-436

  Paula Santos, Nuno ^a,e   Colaço, Aura ^a,b   Gil da Costa, Rui M ^c,d   Manuel Oliveira, Maria ^a   Peixoto, Francisco ^e   Alexandra Oliveira, Paula ^a,c,e  

^a UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^b UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^c UNIVERSITY OF PORTO   (Portugal)

^d PORTUGUESE ONCOLOGY INSTITUTE   (Portugal)

^e UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

Author keywords

Antioxidants; Hepatocellular carcinoma; Liver; Mice; N diethylnitrosamine (DEN); Reactive oxygen species (ROS)

Indexed keywords

CATALASE; DIETHYLNITROSAMINE; GLUTATHIONE; GLUTATHIONE REDUCTASE; SUPEROXIDE DISMUTASE; XANTHINE OXIDASE; ALKYLATING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANISOKARYOSIS; APOPTOSIS; ARTICLE; CARCINOGEN TESTING; CARCINOGENIC ACTIVITY; CELL PROLIFERATION; CHEMICAL ANALYSIS; CHEMICAL INTERACTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATIONAL STUDY; DEHYDRATION; DISEASE COURSE; DISEASE SEVERITY; DYSKARYOSIS; DYSPLASIA; ENVIRONMENTAL EXPOSURE; HISTOPATHOLOGY; LIVER ADENOMA; LIVER CELL CARCINOMA; LIVER DYSPLASIA; LIVER INJURY; LIVER LEVEL; LIVER TOXICITY; LUNG CARCINOGENESIS; MALE; MICROSCOPY; MITOSIS; MOUSE; MOUSE MODEL; MULTIFOCAL NECROSIS; NONHUMAN; OXIDATIVE STRESS; PELIOSIS HEPATIS; TISSUE NECROSIS; TOXICOKINETICS; ANIMAL; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; LIVER; PATHOLOGY; TIME;

ALKYLATING AGENTS; ANIMALS; DIETHYLNITROSAMINE; LIVER; MALE; MICE; MICE, INBRED ICR; OXIDATIVE STRESS; TIME;

EID: 84908495769     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2014.07.002     Document Type: Article

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