Antiinflammatory effects of essential oil from the leaves of Cinnamomum cassia and cinnamaldehyde on lipopolysaccharide-stimulated J774A.1 cells

Journal of Advanced Pharmaceutical Technology and Research

Volumn 5, Issue 4, 2014, Pages 164-170

  Pannee, Chinjarernpan ^a   Chandhanee, Itthipanichpong ^b   Wacharee, Limpanasithikul ^b  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Cinnamaldehyde; Cinnamomum cassia; J774A.1 cells; lipopolysaccharide

Indexed keywords

CINNAMALDEHYDE; CYCLOOXYGENASE 2; ESSENTIAL OIL; FERROPORTIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; IRON EXPORTER FERROPORTIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROSTAGLANDIN E SYNTHASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CINNAMOMUM CASSIA; CONTROLLED STUDY; CYCLOOXYGENASE 2 GENE; DOWN REGULATION; DRUG SCREENING; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SYNTHESIS; GAS CHROMATOGRAPHY; GENE EXPRESSION REGULATION; MOUSE; NITRIC OXIDE SYNTHASE GENE; NONHUMAN; PLANT LEAF; PROSTAGLANDIN E SYNTHASE 1 GENE; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY; UPREGULATION;

EID: 84908460606     PISSN: 22314040     EISSN: 09762094     Source Type: Journal    
DOI: 10.4103/2231-4040.143034     Document Type: Article

References (24)

1. Geng S, Cui Z, Huang X, Chen Y, Xu D, Xiong P. Variations in essential oil yield and composition duringCinnamomum cassiabark growth. Ind Crops Prod 2011;33:248-52.
2. Kurokawa M, Kumeda CA, Yamamura J, Kamiyama T, Shiraki K. Antipyretic activity of cinnamyl derivatives and related compounds in influenza virus-infected mice. Eur J Pharmacol 1998;348:45-51.
3. Nir Y, Potasman I, Stermer E, Tabak M, Neeman I. Controlled trial of the effect of cinnamon extract on Helicobacter pylori. Helicobacter 2000;5:94-7.
4. Rui W, RuiJiang W, Bao Y. Extraction of essential oils from five cinnamon leaves and identification of their volatile compound compositions. Innov Food Sci Emerg Technol 2009;10:289-92.
5. Chao LK, Hua KF, Hsu HY, Cheng SS, Lin IF, Chen CJ, et al. Cinnamaldehyde inhibits pro-inflammatory cytokines secretion from monocytes/macrophages through suppression of intracellular signaling. Food Chem Toxicol 2008;46:220-31.
6. Liao JC, Deng JS, Chiu CS, Hou WC, Huang SS, Shie PH, et al. Anti-Inflammatory activities of Cinnamomum cassia constituents in vitro and in vivo. Evid Based Complement Alternat Med 2012;2012:429320.
7. Atta AH, Alkofahi A. Anti-nociceptive and anti-inflammatory effects of some Jordanian medicinal plant extracts. J Ethnopharmacol 1998;60:117-24.
8. Dugoua JJ, Seely D, Perri D, Cooley K, Forelli T, Mills E, et al. From type 2 diabetes to antioxidant activity: A systematic review of the safety and efficacy of common and cassia cinnamon bark. Can J Physiol Pharmacol 2007;85:837-47.
9. Choi J, Lee KT, Ka H, Jung WT, Jung HJ, Park HJ. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24:418-23.
10. Coleman JW. Nitric oxide in immunity and inflammation. Int Immunopharmacol 2001;1:1397-406.
11. Choi CY, Park KR, Lee JH, Jeon YJ, Liu KH, Oh S, et al. Isoeugenol suppression of inducible nitric oxide synthase expression is mediated by down-regulation of NF-kappaB, ERK1/2, and p38 kinase. Eur J Pharmacol 2007;576:151-9.
12. Lee YY, Hung SL, Pai SF, Lee YH, Yang SF. Eugenol suppressed the expression of lipopolysaccharide-induced proinflammatory mediators in human macrophages. J Endod 2007;33:698-702.
13. Sampey AV, Monrad S, Crofford LJ. Microsomal prostaglandin E synthase-1: The inducible synthase for prostaglandin E2. Arthritis Res Ther 2005;7:114-7.
14. Harris SG, Padilla J, Koumas L, Ray D, Phipps RP. Prostaglandins as modulators of immunity. Trends Immunol 2002;23:144-50.
15. Xiao L, Ornatowska M, Zhao G, Cao H, Yu R, Deng J, et al. Lipopolysaccharide-induced expression of microsomal prostaglandin E synthase-1 mediates late-phase PGE2 production in bone marrow derived macrophages. PLoS One 2012;7:e50244.
16. Shibata-Nozaki T, Ito H, Mitomi H, Akaogi J, Komagata T, Kanaji T, et al. Endogenous prostaglandin E2 inhibits aberrant overgrowth of rheumatoid synovial tissue and the development of osteoclast activity through EP4 receptor. Arthritis Rheum 2011;63:2595-605.
17. Norberg JK, Sells E, Chang HH, Alla SR, Zhang S, Meuillet EJ. Targeting inflammation: Multiple innovative ways to reduce prostaglandin E2. Pharm Pat Anal 2013;2:265-88.
18. Cheng Y, Wang M, Yu Y, Lawson J, Funk CD, Fitzgerald GA. Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function. J Clin Invest 2006;116:1391-9.
19. Rolin J, Maghazachi AA. Implications of chemokines, chemokine receptors, and inflammatory lipids in atherosclerosis. J Leukoc Biol 2014;95:575-85.
20. Eriksson C, Rantapaä-Dahlqvist S. Cytokines in relation to autoantibodies before onset of symptoms for systemic lupus erythematosus. Lupus 2014.
21. Dawson J, Miltz W, Mir AK, Wiessner C. Targeting monocyte chemoattractant protein-1 signalling in disease. Expert Opin Ther Targets 2003;7:35-48.
22. Liu Y, Song M, Che TM, Bravo D, Pettigrew JE. Anti-inflammatory effects of several plant extracts on porcine alveolar macrophages in vitro. J Anim Sci 2012;90:2774-83.
23. Koj A. Termination of acute-phase response: Role of some cytokines and anti-inflammatory drugs. Gen Pharmacol 1998;31:9-18.
24. Ganz T, Nemeth E. Iron sequestration and anemia of inflammation. Semin Hematol 2009;46:387-93.