Study of the protective mechanisms of Compound Danshen Tablet (Fufang Danshen Pian) against myocardial ischemia/reperfusion injury via the Akt-eNOS signaling pathway in rats

Journal of Ethnopharmacology

Volumn 156, Issue , 2014, Pages 190-198

  Qin, Ren An ^a   Lin, Juan ^b   Li, Chuyuan ^a   Fu, Wenjuan ^b   Huang, Chunyan ^b   Yu, Xuemei ^b   Huang, Lin ^a   Nie, Hong ^b  

^a Guangzhou General Pharmaceutical Research Institute Co Ltd   (China)

^b JINAN UNIVERSITY   (China)

Author keywords

Akt; Compound Danshen Tablet; eNOS; Myocardial ischemia reperfusion injury; Protective mechanisms; Signaling pathway

Indexed keywords

CARDIOVASCULAR AGENT; CASPASE 3; CHINESE DRUG; COMPOUND DANSHEN; CREATINE KINASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HERBACEOUS AGENT; LACTATE DEHYDROGENASE; MALONALDEHYDE; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; SULFOTANSHINONE SODIUM; SUPEROXIDE DISMUTASE; TROPONIN I; UNCLASSIFIED DRUG; DAN-SHEN ROOT EXTRACT; FUFANG DANSHEN; NOS3 PROTEIN, RAT; PROTECTIVE AGENT; TABLET;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DRUG DOSAGE FORM COMPARISON; DRUG DOSE COMPARISON; DRUG MEGADOSE; ENZYME ACTIVITY; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; LACTATE DEHYDROGENASE BLOOD LEVEL; LOW DRUG DOSE; MALE; NONHUMAN; PILL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; SALVIA MILTIORRHIZA; SIGNAL TRANSDUCTION; ST SEGMENT; TABLET; TISSUE LEVEL; ANIMAL; CHEMISTRY; DRUG EFFECTS; HEART; HEART MUSCLE CELL; METABOLISM; MYOCARDIAL REPERFUSION INJURY; PANAX NOTOGINSENG; PHARMACOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; CASPASE 3; DRUGS, CHINESE HERBAL; HEART; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; NITRIC OXIDE SYNTHASE TYPE III; PANAX NOTOGINSENG; PROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; SALVIA MILTIORRHIZA; SIGNAL TRANSDUCTION; TABLETS;

EID: 84908454853     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.08.023     Document Type: Article

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