Bioprofiling of platelets in medicated patients with depression

Journal of Affective Disorders

Volumn 172, Issue , 2015, Pages 81-88

  Hüfner, Katharina ^a   Kandler, Christina ^a   Koudouovoh Tripp, Pia ^a   Egeter, Jonas ^a   Hochstrasser, Tanja ^a,c   Stemer, Bettina ^a   Malik, Peter ^a   Giesinger, Johannes ^b   Humpel, Christian ^a   Sperner Unterweger, Barbara ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Aggregation; Bioactivity; Cardiovascular disease; Medication; Platelet

Indexed keywords

AGOMELATINE; AMFEBUTAMONE; BETA THROMBOGLOBULIN; CD31 ANTIGEN; CD40 LIGAND; DOXEPIN; GELATINASE A; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; LITHIUM; MAPROTILINE; MELITRACEN; PADGEM PROTEIN; SEROTONIN; SEROTONIN 1A ANTAGONIST; SEROTONIN 2A ANTAGONIST; SEROTONIN 3 ANTAGONIST; SEROTONIN TRANSPORTER; THROMBOCYTE FACTOR 4; TRAZODONE; ZOLPIDEM; BIOLOGICAL MARKER; PPBP PROTEIN, HUMAN; SEROTONIN UPTAKE INHIBITOR;

ADULT; ARTICLE; BIOLOGICAL ACTIVITY; BLOOD CLOTTING TIME; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INHIBITION CONSTANT; LONG TERM CARE; MAJOR DEPRESSION; MALE; NATURALISTIC INQUIRY; PSYCHOMETRY; PSYCHOPHARMACOTHERAPY; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION ANALYZER; AUSTRIA; BLOOD; CARDIOVASCULAR DISEASE; DEPRESSION; DEPRESSIVE DISORDER, MAJOR; DRUG EFFECTS; METABOLISM; MIDDLE AGED; THROMBOCYTE;

ADULT; AUSTRIA; BETA-THROMBOGLOBULIN; BIOMARKERS; BLOOD PLATELETS; CARDIOVASCULAR DISEASES; CD40 LIGAND; DEPRESSION; DEPRESSIVE DISORDER, MAJOR; FEMALE; HUMANS; INTERLEUKIN-1BETA; MALE; MATRIX METALLOPROTEINASE 2; MIDDLE AGED; PLATELET AGGREGATION; PLATELET FACTOR 4; SEROTONIN; SEROTONIN UPTAKE INHIBITORS;

EID: 84908428504     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2014.09.029     Document Type: Article

References (52)

1. Angiolillo, D.J., Ueno, M., Goto, S., 2010. Basic principles of platelet biology and clinical implications. Circ. J. 74, 597-607.
2. Antoniades, C., Bakogiannis, C., Tousoulis, D., Antonopoulos, A.S., Stefanadis, C., 2009. The CD40/CD40 ligand system: linking inflammation with atherothrombosis. J. Am. Coll. Cardiol. 54, 669-677.
3. Ariyo, A.A., Haan, M., Tangen, C.M., Rutledge, J.C., Cushman, M., Dobs, A., Furberg, C.D., 2000. Depressive symptoms and risks of coronary heart disease and mortality in elderly Americans (Cardiovascular Health Study Collaborative Research Group). Circulation 102, 1773-1779.
4. Atar, D., Malinin, A., Takserman, A., Pokov, A., van Zyl, L., Tanguay, J.F., Lesperance, F., Serebruany, V., 2006. Escitalopram, but not its major metabolites, exhibits antiplatelet activity in humans. J. Clin. Psychopharmacol. 26, 172-177.
5. Backhaus, J., Junghanns, K., Broocks, A., Riemann, D., Hohagen, F., 2002. Test-retest reliability and validity of the Pittsburgh Sleep Quality Index in primary insomnia. J. Psychosom. Res. 53, 737-740.
6. Barbui, C., Hotopf, M., Garattini, S., 2002. Fluoxetine dose and outcome in antidepressant drug trials. Eur. J. Clin. Pharmacol. 58, 379-386.
7. Beck, A.T., Ward, C.H., Mendelson, M., Mock, J., Erbaugh, J., 1961. An inventory for measuring depression. Arch. Gen. Psychiatry 4, 561-571.
8. Benjamini, Y., Hochberg, Y., 1995. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. Ser. B 57, 289-300.
9. Bismuth-Evenzal, Y., Gonopolsky, Y., Gurwitz, D., Iancu, I., Weizman, A., Rehavi, M., 2012. Decreased serotonin content and reduced agonist-induced aggregation in platelets of patients chronically medicated with SSRI drugs. J. Affect. Disord. 136, 99-103.
10. Booth, M., 2000. Assessment of physical activity: an international perspective. Res. Q. Exerc. Sport 71, S114-S120.
11. Bruce, E.C., Musselman, D.L., 2005. Depression, alterations in platelet function, and ischemic heart disease. Psychosom. Med. 67 (Suppl 1), S34-S36.
12. Brugha, T., Bebbington, P., Tennant, C., Hurry, J., 1985. The List of Threatening Experiences: a subset of 12 life event categories with considerable long-term contextual threat. Psychol. Med. 15, 189-194.
13. Camacho, A., Dimsdale, J.E., 2000. Platelets and psychiatry: lessons learned from old and new studies. Psychosom. Med. 62, 326-336.
14. Carney, R.M., Freedland, K.E., 2003. Depression, mortality, and medical morbidity in patients with coronary heart disease. Biol. Psychiatry 54, 241-247.
15. Celano, C.M., Huffman, J.C., 2011. Depression and cardiac disease: a review. Cardiol. Rev. 19, 130-142.
16. Cleanthis, M., Smout, J., Bhattacharya, V., Ashour, H., Dyker, A., Ford, G.A., Mikhailidis, D.P., Stansby, G.P., 2008. Soluble but not platelet P-selectin correlates with spontaneous platelet aggregation: a pilot study. Clin. Appl. Thromb. Hemost. 14, 227-233.
17. Cohen, S., Kamarck, T., Mermelstein, R., 1983. A global measure of perceived stress. J. Health Soc. Behav. 24, 385-396.
18. Dantzer, R., O'Connor, J.C., Freund, G.G., Johnson, R.W., Kelley, K.W., 2008. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat. Rev. Neurosci. 9, 46-56.
19. Ehrlich, D., Humpel, C., 2014. Effects of ethanol on aggregation, serotonin release, and amyloid precursor protein processing in rat and human platelets. Platelets 25, 16-22.
20. Galan, A.M., Lopez-Vilchez, I., Diaz-Ricart, M., Navalon, F., Gomez, E., Gasto, C., Escolar, G., 2009. Serotonergic mechanisms enhance platelet-mediated thrombogenicity. Thromb. Haemost. 102, 511-519.
21. Halperin, D., Reber, G., 2007. Influence of antidepressants on hemostasis. Dialogues Clin. Neurosci. 9, 47-59.
22. Hergovich, N., Aigner, M., Eichler, H.G., Entlicher, J., Drucker, C., Jilma, B., 2000. Paroxetine decreases platelet serotonin storage and platelet function in human beings. Clin. Pharmacol. Ther. 68, 435-442.
23. Hoffman, B.B., Michel, T., Brenneman, T.B., Lefkowitz, R.J., 1982. Interactions of agonists with platelet alpha 2-adrenergic receptors. Endocrinology 110, 926-932.
24. Hotopf, M., Chidgey, J., Addington-Hall, J., Ly, K.L., 2002. Depression in advanced disease: a systematic review Part 1. Prevalence and case finding. Palliat. Med. 16, 81-97.
25. Kamath, S., Blann, A.D., Caine, G.J., Gurney, D., Chin, B.S., Lip, G.Y., 2002. Platelet P-selectin levels in relation to plasma soluble P-selectin and betathromboglobulin levels in atrial fibrillation. Stroke 33, 1237-1242.
26. Katon, W., Schulberg, H., 1992. Epidemiology of depression in primary care. Gen. Hosp. Psychiatry 14, 237-247.
27. Kuijpers, P.M., Hamulyak, K., Strik, J.J., Wellens, H.J., Honig, A., 2002. Betathromboglobulin and platelet factor 4 levels in post-myocardial infarction patients with major depression. Psychiatry Res. 109, 207-210.
28. Le Quan-Bui, K.H., Plaisant, O., Leboyer, M., Gay, C., Kamal, L., Devynck, M.A., Meyer, P., 1984. Reduced platelet serotonin in depression. Psychiatry Res. 13, 129-139.
29. Lee, S., Jeong, J., Kwak, Y., Park, S.K., 2010. Depression research: where are we now? Mol. Brain 3, 8.
30. Leo, R., Di Lorenzo, G., Tesauro, M., Razzini, C., Forleo, G.B., Chiricolo, G., Cola, C., Zanasi, M., Troisi, A., Siracusano, A., Lauro, R., Romeo, F., 2006. Association between enhanced soluble CD40 ligand and proinflammatory and prothrombotic states in major depressive disorder: pilot observations on the effects of selective serotonin reuptake inhibitor therapy. J. Clin. Psychiatry 67, 1760-1766.
31. Liu, X.H., Grund, F., Kanellopoulos, G.K., Kvernebo, K., Ilebekk, A., 2003. Myocardial extracellular signal regulatory kinases are activated by laser treatment. J. Cardiovasc. Surg. (Torino) 44, 1-7.
32. Marksteiner, J., Kemmler, G., Weiss, E.M., Knaus, G., Ullrich, C., Mechtcheriakov, S., Oberbauer, H., Aufinger, S., Hinterholzl, J., Hinterhuber, H., Humpel, C., 2011. Five out of 16 plasma signaling proteins are enhanced in plasma of patients with mild cognitive impairment and Alzheimer's disease. Neurobiol. Aging 32, 539-540.
33. Mendoza-Sotelo, J., Torner, C., Alvarado-Vasquez, N., Lazo-Langner, A., Lopez, G., Arango, I., Pavon, L., Gonzalez-Trujano, E., Moreno, J., 2010. Ultrastructural changes and immunolocalization of P-selectin in platelets from patients with major depression. Psychiatry Res. 176, 179-182.
34. Michelson, A.D., Barnard, M.R., Hechtman, H.B., MacGregor, H., Connolly, R.J., Loscalzo, J., Valeri, C.R., 1996. In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proc. Natl. Acad. Sci. USA 93, 11877-11882.
35. Montgomery, S.A., Asberg, M., 1979. A new depression scale designed to be sensitive to change. Br. J. Psychiatry 134, 382-389.
36. Morel-Kopp, M.C., McLean, L., Chen, Q., Tofler, G.H., Tennant, C., Maddison, V., Ward, C.M., 2009. The association of depression with platelet activation: evidence for a treatment effect. J. Thromb. Haemost. 7, 573-581.
37. Muller-Oerlinghausen, B., Roggenbach, J., Franke, L., 2004. Serotonergic platelet markers of suicidal behavior-do they really exist? J. Affect. Disord. 79, 13-24.
38. Musselman, D.L., Marzec, U.M., Manatunga, A., Penna, S., Reemsnyder, A., Knight, B.T., Baron, A., Hanson, S.R., Nemeroff, C.B., 2000. Platelet reactivity in depressed patients treated with paroxetine: preliminary findings. Arch. Gen. Psychiatry 57, 875-882.
39. Pan, A., Sun, Q., Okereke, O.I., Rexrode, K.M., Hu, F.B., 2011. Depression and risk of stroke morbidity and mortality: a meta-analysis and systematic review. JAMA 306, 1241-1249.
40. Pizzi, C., Santarella, L., Costa, M.G., Manfrini, O., Flacco, M.E., Capasso, L., Chiarini, S., Di Baldassarre, A., Manzoli, L., 2012. Pathophysiological mechanisms linking depression and atherosclerosis: an overview. J. Biol. Regul. Homeost. Agents 26, 775-782.
41. Sawicki, G., Sanders, E.J., Salas, E., Wozniak, M., Rodrigo, J., Radomski, M.W., 1998. Localization and translocation of MMP-2 during aggregation of human platelets. Thromb. Haemost. 80, 836-839.
42. Serebruany, V.L., Glassman, A.H., Malinin, A.I., Nemeroff, C.B., Musselman, D.L., van Zyl, L.T., Finkel, M.S., Krishnan, K.R., Gaffney, M., Harrison, W., Califf, R.M., O'Connor, C.M., Sertraline Anti Depressant Heart Attack Randomized Trial Study, G., 2003. Platelet/endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events: the Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART) Platelet Substudy. Circulation 108, 939-944.
43. Serebruany, V.L., Gurbel, P.A., O'Connor, C.M., 2001a. Platelet inhibition by sertraline and N-desmethylsertraline: a possible missing link between depression, coronary events, and mortality benefits of selective serotonin reuptake inhibitors. Pharmacol. Res. 43, 453-462.
44. Serebruany, V.L., O'Connor, C.M., Gurbel, P.A., 2001b. Effect of selective serotonin reuptake inhibitors on platelets in patients with coronary artery disease. Am. J. Cardiol. 87, 1398-1400.
45. Sheehan, D.V., Lecrubier, Y., Sheehan, K.H., Amorim, P., Janavs, J., Weiller, E., Hergueta, T., Baker, R., Dunbar, G.C., 1998. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry 59 (20), 22-33 (quiz 34-57).
46. Sheu, J.R., Fong, T.H., Liu, C.M., Shen, M.Y., Chen, T.L., Chang, Y., Lu, M.S., Hsiao, G., 2004. Expression of matrix metalloproteinase-9 in human platelets: regulation of platelet activation in in vitro and in vivo studies. Br. J. Pharmacol. 143, 193-201.
47. van Zyl, L.T., Lesperance, F., Frasure-Smith, N., Malinin, A.I., Atar, D., Laliberte, M.A., Serebruany, V.L., 2009. Platelet and endothelial activity in comorbid major depression and coronary artery disease patients treated with citalopram: the Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy Trial (CREATE) biomarker sub-study. J. Thromb. Thrombolysis 27, 48-56.
48. von Kanel, R., 2004. Platelet hyperactivity in clinical depression and the beneficial effect of antidepressant drug treatment: how strong is the evidence? Acta Psychiatr. Scand. 110, 163-177.
49. Walsh, M.T., Dinan, T.G., Condren, R.M., Ryan, M., Kenny, D., 2002. Depression is associated with an increase in the expression of the platelet adhesion receptor glycoprotein Ib. Life Sci. 70, 3155-3165.
50. Weyrich, A.S., Lindemann, S., Zimmerman, G.A., 2003. The evolving role of platelets in inflammation. J. Thromb. Haemost. 1, 1897-1905.
51. Ziegelstein, R.C., Parakh, K., Sakhuja, A., Bhat, U., 2007. Depression and coronary artery disease: is there a platelet link? Mayo Clin. Proc. 82, 1366-1368.
52. Zimmerman, M., Coryell, W., Stangl, D., Pfohl, B., 1987. Validity of an operational definition for neurotic unipolar major depression. J. Affect. Disord. 12, 29-40.