Serotonergic platelet markers of suicidal behavior - Do they really exist?

Journal of Affective Disorders

Volumn 79, Issue 1-3, 2004, Pages 13-24

  Muller Oerlinghausen B ^a,c   Roggenbach, J ^a   Franke, L ^b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c NONE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; DESIPRAMINE; IMIPRAMINE; NEUROLEPTIC AGENT; PAROXETINE; SEROTONIN; SEROTONIN 2 RECEPTOR; SEROTONIN TRANSPORTER; TRICYCLIC ANTIDEPRESSANT AGENT;

BINDING SITE; BLEEDING; DEPRESSION; DILUTION; DRUG RECEPTOR BINDING; ENZYME INHIBITION; HUMAN; MAJOR DEPRESSION; PRIORITY JOURNAL; REPRODUCIBILITY; REVIEW; SCHIZOPHRENIA; SEROTONIN UPTAKE; SUICIDAL BEHAVIOR; SUICIDE ATTEMPT; THROMBOCYTE; VIOLENCE;

EID: 17644434581     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0327(02)00367-1     Document Type: Article

References (83)

1. Alvarez J.C., Cremniter D., Lesieur P., Gregoire A., Gilton A., Macquin-Mavier I., Jarreau C., Spreux-Varoquaux O. Low blood cholesterol and low platelet serotonin levels in violent suicide attempters. Biol. Psychiatry. 45:1999;1066-1069.
2. Anthenelli R.M., Tipp J., Li T.K., Magnes L., Schuckit M.A., Rice J., Daw W., Nurnberger J.I. Platelet monoamine oxidase activity in subgroups of alcoholics and controls; results from the collaborative study on the genetics of alcoholism. Alcohol Clin. Exp. Res. 22:1998;598-604.
3. Apter A., Van Praag H.M., Plutchik R., Sevy S., Korn M., Brown S.L. Interrelationships among anxiety, aggression, impulsivity, and mood: A serotonergically linked cluster? Psychiatry Res. 32:1990;191-199.
4. Apter A., Plutchik R., Van Praag H.M. Anxiety, impulsivity and depressed mood in relation to suicidal and violent behavior. Acta Psychiatr. Scand. 87:1993;1-5.
5. Arango V., Underwood M., Mann J.J. Alterations in monoamine receptors in the brain of suicide victims. J. Clin. Psychopharmacol. 12:(No. 2):1992;8S-12S.
6. 3H-LSD) in the blood platelets of depressed patients. Life Sci. 44:1989;725-734.
7. 3H]-imipramine binding; Studies in the frontal cortex of normal controls and suicide victims. Biol. Psychiatry. 29:1991;1016-1022.
8. 2 receptor bindings in blood platelets of schizophrenic patients. Psychiatry Res. 47:1993;111-119.
9. Asberg M., Träskmann L., Thoren P. 5-HIAA in cerebrospinal fluid. A biochemical suicide predictor? Arch. Gen. Psychiatry. 33:1976;1193-1197.
10. Askenazy F., Caci H., Myquel M., Darcourt G., Lecrubier Y. Relationship between impulsivity and platelet serotonin content in adolescents. Psychiatry Res. 94:(1):2000;19-28.
11. Bakish D., Cavazzoni P., Chudzik J., Ravindran A., Hrdina P. Effects of selective serotonin reuptake inhibitors on platelet serotonin parameters in major depressive disorder. Biol. Psychiatry. 41:1997;184-190.
12. 2 receptor binding on blood platelets - a peripheral marker for depression? Life Sci. 41:1987;2485-2492.
13. 2 receptor binding on blood platelets of suicidal men. Psychopharmcology. 100:1990;165-167.
14. Bräunig P., Rao M.L., Fimmers R. Blood serotonin in suicidal schizophrenic patients. Acta Psychiatr. Scand. 79:1989;186-189.
15. 3H]-5-HT uptake: effect of administration of various antidepressant treatments. Neuropharmacology. 32:1993;737-743.
16. Coccaro E.F., Siever L.J., Klar H.M., Maurer G., Cochrane K., Cooper T.B., Mohs R.C., Davis K.L. Serotonergic studies in patients with affective and personality disorders. Arch. Gen. Psychiatry. 46:1989;587-599.
17. Cowen P.J., Charig E.M., Fraser S., Elliot J.M. Platelet 5-HT receptor binding during depressive illness and tricyclic antidepressant treatment. J. Affect. Disord. 13:1987;45-50.
18. Cremniter D., Jamain S., Kollenbach K., Alvarez J.C., Lecrubier Y., Gilton A., Spreux-Varoquaux O. CSF 5-HIAA and HVA levels are lower in impulsive as compared to non impulsive suicide attempters and controls immediately after violent suicide attempt. Biol. Psychiatry. 42:1999;S212.
19. 3H] imipramine. J. Pharmacol. Exp. Ther. 242:(1):1987;364-371.
20. 3H] paroxetine to platelets of depressed patients: Seasonal differences and effects of diagnostic classification. J. Affect. Disord. 32:1994;27-35.
21. Elliot J.M. Platelet receptor binding studies in affective disorders. J. Affect. Disord. 6:1984;219-239.
22. Ellis P.M., Slamond C. Is platelet imipramine binding reduced in depression? A meta-analysis. Biol. Psychiatry. 36:1994;292-299.
23. Franke L., Schewe H.J., Müller B., Campman V., Kitzrow W., Uebelhack R., Thies-Flechtner K., Berghöfer A., Müller-Oerlinghausen B. Serotonergic platelet variables in unmedicated patients suffering from major depression and healthy subjects. Life Sci. 67:(3):2000;301-305.
24. Franke, L., 2001. Thrombozytäre 5-HT-Konzentration und -Aufnahmeaktivität bei mono- und bipolaren Depressionen: Geschlechtsspezifische Unterschiede und Suizidalität. In: Bronisch, T., Felber, W. (Eds.), Neurobiologie suizidalen Verhaltens. Roederer Verlag, Regensburg, pp. 84-105.
25. Halbreich U., Rojansky N., Zander K.J., Barkai A. Influence of age, sex and diurnal variability on imipramine recepror binding and serotonin uptake in platelets of normal subjects. J. Psychiat. Res. 25:1991;7-18.
26. Hobisch-Hagen P., Jelkman W., Mayr A., Wiedermann F.J., Fries D., Herold M., Klingler A., Schobsberger W. Low platelet count and elevated serum thrombopoietin after severe trauma. Eur. J. Haematol. 64:(3):2000;157-163.
27. 3H] imipramine defined binding in intact human platelets. Biol. Psychiatry. 25:1989;576-584.
28. 2 sites in cortex and amygdala. Brain Res. 614:1993;37-44.
29. 2A receptors unchanged by antidepressant treatment. Psychiatry Res. 66:1997;73-85.
30. 3H] paroxetine, in antidepressant-free depressed suicides. Brain Res. 526:1990;17-22.
31. 3H]paroxetine, in controls and depressed patients before and after treatment with fluoxetine or lofepramine. Psychopharmacology. 115:1994;261-264.
32. Lesch K.P., Gross J., Franzek E., Wolozin B., Riederer P., Murphy D.L. Primary structure of the serotonin transporter in unipolar depression and bipolar disorder. Biol. Psychiatry. 37:1995;215-223.
33. Little K.Y., McLauglin D.P., Ranc J., Gilmore J., Lopez J.F., Watson S.J., Carroll F.I., Butts J.D. Serotonin transporter binding sites and mRNA levels in depressed persons committing suicide. Biol. Psychiatry. 41:1997;1156-1164.
34. 3H-paroxetine binding to platelets from healthy volunteers. Biol. Psychiatry. 34:1993;356-360.
35. Malone K.M., Corbitt E.M., Li S., Mann J.J. Prolactin response to fenfluramine and suicide attempt lethality in major depression. Br. J. Psychiatry. 168:1996;324-329.
36. Mann J.J., Stanley M. Postmortem monoamine oxidase enzyme kinetics in the frontal cortex of suicide victims and controls. Acta Psychiatr. Scand. 69:1984;135-139.
37. Mann J.J., McBride P.A., Anderson G.M., Mieczkowski T.A. Platelet and whole blood serotonin content in depressed inpatients: correlations with acute and lifetime psychopathology. Biol. Psychiatry. 32:1992;243-257.
38. Mann J.J., McBride A., Brown R.P., Linnoila M., Leon A.C., DeMeo M., Mieczkowski T., Myers J.E., Stanley M. Relationship between central and peripheral serotonin indexes in depressed and suicidal psychiatric inpatients. Arch Gen. Psychiatry. 49:1992;442-446.
39. Marazziti D., Rotondo A., Presta S., Pancioli-Guadagnucci M.L., Palego L., Conti L. Role of serotonin in human aggressive behavior. Aggres. Behav. 19:1993;347-353.
40. Marazziti D., Placidi G.F., Cassano G.B., Akiskal H. Lack of specificity of reduced platelet imipramine binding in different psychiatric conditions. Psychiatry Res. 30:1989;21-29.
41. 2 receptor indices to major depressive disorder, personality traits, and suicidal behavior. Biol. Psychiatry. 35:1994;295-308.
42. Meltzer H.Y., Umberkoman-Wiita B., Robertson A., Tricou B.J., Lowy M., Perline R. Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorder-I. Enhanced response in depression and mania. Arch. Gen. Psychiatry. 41:1984;366-374.
43. Meltzer H., Arora A. Platelet markers of suicidality. Ann. NY Acad. Sci. 487:1986;271-280.
44. Meltzer H.Y., Arora R.C. Platelet serotonin studies in affective disorders: evidence for a serotonergic abnormality. Sandler M., Coppen A., Harnett S. 5-hydroxytryptamine in Psychiatry - a Spectrum of Ideas. 1991;50-87 Oxford University Press, Oxford-New York-Tokyo.
45. Mendez-Alvarez E., Soto-Otero R., Sanchez-Sellero I., Lopez-Rivadulla-Lamas M. Inhibition of brain monoamine oxidase by adducts of 1,2,3,4-tetrahydroisoquinolone with components of cigarette smoke. Life Sci. 60:1997;1719-1727.
46. Modai I., Apter A., Meltzer M., Tyano S., Walewski A., Jerushalmy Z. Serotonin uptake by platelets of suicidal and aggressive adolescents psychiatric inpatients. Neuropsychobiology. 21:1989;9-13.
47. Mück-Seler D., Jakovljevic M., Pivac N. Platelet 5-HT concentrations and suicidal behavior in recurrent major depression. J. Affect. Disord. 39:1996;73-80.
48. 2-rezeptorbindung an gesunden versuchspersonen und depressiven patienten. Möller H.J., Müller-Spahn F., Kurtz G. Aktuelle Perspektiven Der Biologischen Psychiatry. 1996;169-171 Springer, Wien, New York.
49. Neuger J., El Khoury A., Kjellman B.F., Wahlund B., Aberg-Wistedt A., Stain-Malmgren R. Platelet serotonin functions in untreated major depression. Psychiatry Res. 85:1999;189-198.
50. Norman T.R., Chamberlain K.G., French M.A., Burrows G.D. Platelet monoamine oxidase activity and cigarette smoking. J. Affect. Disord. 4:1982;73-77.
51. Oreland L., Wiberg A., Asberg M., Träskman L., Sjöstrand L., Thoren P., Bertilsson L., Tybring G. Platelet MAO activity and monoamine metabolites in cerebrospinal fluid in depressed and suicidal patients and in healthy controls. Psychiatry Res. 4:1981;21-29.
52. Owen F., Chambers D.R., Cooper S.J., Crow T.J., Johnson J.A., Lofthouse R., Poulter M. Serotonergic mechanisms in brains of suicide victims. Brain Res. 362:(1):1986;185-188.
53. Pandey G.N., Pandey S.C., Janicak P.G., Marks R.C., Davis J.M. Platelet serotonin-2 receptor binding sites in depression and suicide. Biol. Psychiatry. 28:1990;215-222.
54. Pandey G.N., Pandey S.C., Dwivedi Y., Sharma R., Janicak P.G., Davis J.M. Platelet serotonin-2A receptors: A potential marker for suicidal behavior. Am. J. Psychiatry. 152:(6):1995;850-855.
55. 3H} imipramine binding in adolescents who attempted suicide. Am. J. Psychiatry. 152:(6):1995;923-925.
56. 3H-Imipramine binding and serotonin uptake in platelets from untreated patients and control volunteers. Psychopharmacology. 77:(4):1982;332-335.
57. Rao M.L., Bräunig P., Papassotiropoulos A. Autoaggressive behavior is closely related to serotonin availability in schizoaffective disorder. Pharmacopsychiatry. 27:1994;202-206.
58. 2-rezeptors begleitet. Möller H.J., Müller-Spahn F., Kurtz G. Aktuelle Perspektiven Der Biologischen Psychiatry. 1996;155-157 Springer, Wien, New York.
59. 2A receptor and low blood serotonin in suicidal psychiatric patients. Neuropsychobiology. 38:1998;84-89.
60. Rihmer Z. The influence of latitude on imipramine platelet binding sites. Pharmacopsychiatry. 24:1991;32-33.
61. 3H-paroxetine binding sites in suicide brains. Psychiatry Res.: Neuroimaging Sect. 82:1998;161-170.
62. 3H]paroxetine binding sites in platelets from depressed patients. J. Affect. Disord. 52:1999;225-233.
63. Ross S.B., Jansa S., Wettenberg L., Fyrö B., Hellner B. Decreased blood level of 5-hydroxytryptamine by inhibitors of the membranal hydroxytryptamine uptake. Life Sci. 19:1976;205-210.
64. Roy A., Everett D., Pickar D., Paul S.M. Platelet tritiated imipramine binding and serotonin uptake in depressed patients and controls. Arch. Gen. Psychiatry. 44:1987;320-327.
65. Roy A. Suicidal behavior in depression: relationship to platelet serotonin transporter. Neuropsychobiology. 39:1999;71-75.
66. Sheline Y.I., Bardgett M.E., Jackson J.L., Newcomer J.W., Csernacky J.G. Platelet serotonin markers and depressive symptomatology. Biol. Psychiatry. 37:1995;442-447.
67. 3H]paroxetine to serotonin uptake sites in platelets from healthy volunteers. Biol. Psychiatry. 43:1998;774-780.
68. Stahl S.M., 1985. Platelets as pharmacological models for the receptors and biochemistry of monoaminergic neurons. In: Longenecker (Ed.), The Platelets: Physiology and Pharmacology, pp. 307-340.
69. 2 receptor binding sites re-evaluated: a criticism of recurrent techniques. J. Neural Transm. 92:1993;11-24.
70. 3H-Imipramine binding to freshly prepared platelet membranes in depression. Psychiatry Res. 29:1989;87-103.
71. Träskman-Bendz L., Alling C., Oreland L., Regnell G., Vinge E., Öhman R. Prediction of suicidal behavior from biologic tests. J. Clin. Psychopharmacol. 12:(2):1992;21S-26S.
72. Tripodianakis J., Markianos M., Sarantidis D., Spyropoulou G., Taktikou V., Bistolaki E. Platelet MAO activity in patients with dysthymic disorder. Psychiatry Res. 78:1998;173-178.
73. Turecki G., Briere R., Dewar K., Antonetti T., Lesage A.D., Seguin M., Chawky N., Vanier C., Alda M., Joober R., Benkelfat C., Rouleau G.A. Prediction of level of serotonin 2a receptor binding by serotonin receptor 2a genetic variation in postmortem brain samples from subjects who did or did not commit suicide. Am. J. Psychiatry. 156:1999;1456-1458.
74. Van Kempen G.M.J., Notten P., Hengeveld M.W. Repeated measures of platelet MAO activity and 5-HT in a group of suicidal women. Biol. Psychiatry. 31:1992;529-530.
75. Van Praag H.M., Asnis G.M., Kahn R.S., Brown S.L., Korn M., Harkavy Friedman J.M., Wetzler S. Nosological tunnel vision in biological psychiatry. Ann. NY Acad. Sci. 600:1990;501-508.
76. Van Praag H.M. Serotonin-related, anxiety/aggression-driven, stressor precipitated depression. A psychobiological hypothesis. Eur. Psychiatry. 11:1996;57-67.
77. Van Praag H.M. Nosologomania: a disorder of psychiatry. World J. Biol. Psychiatry. 1:2000;151-158.
78. Verkes R.J., Pijl H., Meinders A.E., Van Kempen G.M.J. Borderline personality, impulsiveness, and platelet monoamine measures in bulimia nervosa and recurrent suicidal behavior. Biol. Psychiatry. 40:1996;173-180.
79. 3H] paroxetine binding correlate with recurrence of suicidal behavior. Psychopharmacology. 132:1997;89-94.
80. 3H] paroxetine binding related to impulsive suicide attempts and borderline personality disorder. Biol. Psychiatry. 43:1998;740-746.
81. 3H-Imipramine binding in platelets from untreated depressed patients compared to healthy controls. Psychiatry Res. 16:1985;131-139.
82. Young W.F., Laws E.R., Sharbrough F.W., Weinshilboum R.M. Human monoamine oxidase - lack of brain and platelet correlation. Arch. Gen. Psychiatry. 43:1986;604-609.
83. Zhang L., Ma W., Barker J.L., Rubinow D.R. Sex differences in expression of serotonin receptors (subtypes 1A and 2A) in rat brain: a possible role of testosterone. Neuroscience. 94:(1):1999;251-259.