Thymol and eugenol derivatives as potential antileishmanial agents

Bioorganic and Medicinal Chemistry

Volumn 22, Issue 21, 2014, Pages 6250-6255

  De Morais, Selene Maia ^a   Vila Nova, Nadja Soares ^a   Bevilaqua, Claudia Maria Leal ^a   Rondon, Fernanda Cristina ^a   Lobo, Carlos Henrique ^b   De Alencar Araripe Noronha Moura, Arlindo ^b   Sales, Antônia Débora ^a   Rodrigues, Ana Paula Ribeiro ^a   De Figuereido, José Ricardo ^a   Campello, Claudio Cabral ^a,c   Wilson, Mary E ^d   De Andrade, Heitor Franco ^e  

^a STATE UNIVERSITY OF CEARÁ   (Brazil)

^b FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^c Campus Do Itaperi   (Brazil)

^d UNIVERSITY OF IOWA   (United States)

^e UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Eugenol; Leishmania infatum chagasi; Thymol

Indexed keywords

ACETIC ACID DERIVATIVE; ACETYLEUGENOL; ACETYLTHYMOL; AMPHOTERICIN B; ANTILEISHMANIAL AGENT; BENZOYLEUGENOL; BENZOYLTHYMOL; EUGENOL; MEGLUMINE ANTIMONATE; PENTAMIDINE; THYMOL; UNCLASSIFIED DRUG; ANTIPROTOZOAL AGENT;

AMASTIGOTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GROWTH INHIBITION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LEISHMANIA CHAGASI; LEISHMANIASIS; LIVER; LUCIFERASE ASSAY; MALE; MOUSE; NONHUMAN; PROMASTIGOTE; SPLEEN; TOXICITY TESTING; ANALOGS AND DERIVATIVES; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CHEMISTRY; DRUG EFFECTS; HUMAN; LEISHMANIA INFANTUM; LEISHMANIASIS, VISCERAL; MACROPHAGE; PARASITOLOGY;

ANIMALS; ANTIPROTOZOAL AGENTS; CELL LINE; EUGENOL; HUMANS; LEISHMANIA INFANTUM; LEISHMANIASIS, VISCERAL; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; THYMOL;

EID: 84908409520     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2014.08.020     Document Type: Article

References (39)

1. C.M.F. Gontijo, and M.N. Melo Rev. Bras. Epidemiol. 7 2004 338
2. S. Rath, L.A. Trivelin, T.R. Imbrunito, D.M. Tomazela, M.N. Jesús, P.C. Marzal, H.F. Andrade, and A.G. Tempone Quim. Nova 26 2003 550
3. J.A.L. Lindoso, J.M.L. Costa, and I.T.Q.H. Goto Res. Rep. Trop. Med. 3 2012 69
4. World Health Organization http://www.who.int/zoonoses/diseases /leishmaniasis/en/, access August of 2013.
5. J. Anthony, L. Fyfe, and H. Smith Trends Parasitol. 21 2005 462
6. L. Gobbo-Neto, and N.P. Lopes Quim. Nova 30 2007 374
7. P. Mishra, A. Kumar, P. Khare, S. Gupta, N. Kumar, and A. Dube J. Med. Microbiol. 58 2009 1058
8. A. Guarda, J.F. Rubilar, J. Miltz, and M.J. Galotto Int. J. Food Microbiol. 146 2011 144
9. A.A. Catherine, H. Deepika, and P.S. Negi J. Essent. Oil Res. 24 2012 481
10. K.R. Riella, R.R. Marinho, J.S. Santos, R.N. Pereira-Filho, J.C. Cardoso, R.L.C. Albuquerque-Junior, and S.M. Thomazzi J. Ethnopharmacol. 143 2012 656
11. T.F. Bachiega, J.P.B. Sousa, J.K. Bastos, and J.M. Sforcin J. Pharm. Pharm. Sci. 64 2012 610
12. A. Ahmad, A. Khan, S. Yousuf, L.A. Khan, and N. Manzoor Fitoterapia 81 2010 1157
13. V.D. Nair, R. Gopi, M. Mohankumar, J. Kavina, and R. Panneersalvam Acta Physiol. Plant 34 2012 599
14. U. Underger, A. Basaran, G.H. Degen, and N. Basaran Food Chem. Toxicol. 47 2009 2037
15. S. Fujisawa, T. Atsumi, Y. Kadoma, and H. Sakagami Toxicology 177 2002 39
16. L.M. Pessoa, S.M. Morais, C.M.L. Bevilaqua, and J.H.S. Luciano Vet. Parasitol. 109 2002 59
17. S.M. Ali, A.A. Khan, I. Ahmed, M. Musaddiq, K.S. Ahmed, H. Polasa, L.V. Rao, C.M. Habibullah, L.A. Sechi, and N. Ahmed Ann. Clin. Microbiol. Antimicrob. 4 2005 20
18. M.A. Botelho, N.A.P. Nogueira, G.M. Bastos, S.C. Fonseca, T.L. Lemos, F.J. Matos, D. Montenegro, J. Heukelbach, V.S. Rao, and G.A. Brito Braz. J. Med. Biol. Res. 40 2007 349
19. S. Robledo, E. Osorio, D. Muñoz, L.M. Jaramillo, A. Restrepo, and G. Arango Antimicrob. Agents Chemother. 49 2005 1652
20. V. Arango, J.J. Dominguez, W. Cardona, S.M. Robledo, D.L. Muñoz, B. Figadere, and J. Sáez Med. Chem. Res. 21 2012 3445
21. M.G.F. Medeiros, A.C. Silva, A.M.G.L. Cito, A.R. Borges, S.G. Lima, and J.A. Lopes Parasitol. Int. 60 2011 237
22. T. Ueda-Nakamura, R.R. Mendonça-Filho, J.A. Morgado-Díaz, P.K. Maza, B.P. Dias, D.A.G. Cortez, D.S. Alviano, M.S.S. Rosa, A.H.C.S. Lopes, C.S. Alviano, and C.V. Nakamura Parasitol. Int. 55 2006 99
23. MS - Ministério da Saúde do Brasil, Manual of Vigilance and Control of Visceral Leishmaniasis, 2006.
24. B. Furniss, A. Hannaford, P. Smith, and A. Tatchell Vogel's Textbook of Practical Organic Chemistry 1989 Prentice Hall London
25. C.J. Thalhofer, J.W. Graff, L. Love-Homan, S.M. Hickerson, N. Craft, S.M. Beverley, and M.E. Wilson J. Vis. Exp. 2010 1980 41
26. T. Lang, S. Goyard, M. Lebastard, and G. Milon Cell. Microbiol. 7 2005 383
27. R.M.F. Piazza, H.F. Andrade, E.S. Umezawa, M. Katzin, and A.M.S. Stolf Acta Trop. 57 1994 301
28. A.G. Tempone, S.E.T. Borborema, H.F. Andrade, N.C.A. Gualda, A. Yogi, C.S. Cravalho, D. Bachiega, F.N. Lupo, S.V. Bonotto, and D.C.H. Fischer Phytomedicine 12 2005 382
29. G.F. Spath, and M.B. Stephen Exp. Parasitol. 99 2001 97
30. J. Mikus, M. Harkenthal, D. Steverding, and J. Reichling Planta Med. 66 2000 366
31. Y. Huang, S. Ho, H. Lee, and Y. Yap J. Stored Prod. Res. 38 2002 403
32. L.F. Interaminense, D.M. Jucá, P.J. Magalhães, J.H. Leal-Cardoso, G.P. Duarte, and S. Lahlou Fundam. Clin. Pharmacol. 21 2007 497
33. L. Jirovetz, G. Buchbauer, I. Stoilova, A. Stoyanova, A. Krastonov, and E. Schmidt J. Agr. Food Chem. 54 2006 6303
34. A. Kaur, R. Singh, C.S. Dey, S.S. Sharma, K.K. Bhutani, and I.P. Singh J. Exp. Biol. 48 2010 314
35. M. Takahashi, H. Fuchino, S. Sekita, and M. Satake Phytother. Res. 18 2004 573
36. G.F. Santoro, M.G. Cardoso, L.G.L. Guimarães, L.Z. Mendonça, and M.J. Soares Exp. Parasitol. 116 2007 283
37. M. Machado, A.M. Dinis, L. Salgueiro, J.B. Custódio, C. Cavaleiro, and M.C. Sousa Exp. Parasitol. 127 2011 732
38. Y.D. Paila, B. Saha, and A. Chattopadhyay Biochem. Biophys. Res. Commun. 399 2010 429
39. N. Dinesh, P.K. Kaur, K.K. Swamy, and S. Singh Exp. Parasitol. 144 2014 84