-
1
-
-
33744480811
-
Managing the symptoms of multiple sclerosis: a multimodal approach
-
Crayton HJ, Rossman HS. Managing the symptoms of multiple sclerosis: a multimodal approach. Clin Ther. 2006;28:445-460.
-
(2006)
Clin Ther
, vol.28
, pp. 445-460
-
-
Crayton, H.J.1
Rossman, H.S.2
-
2
-
-
78349289202
-
Pharmacological management of symptoms in multiple sclerosis: current approaches and future directions
-
Thompson AJ, Toosy AT, Ciccarelli O. Pharmacological management of symptoms in multiple sclerosis: current approaches and future directions. Lancet Neurol. 2010;9:1182-1199.
-
(2010)
Lancet Neurol
, vol.9
, pp. 1182-1199
-
-
Thompson, A.J.1
Toosy, A.T.2
Ciccarelli, O.3
-
3
-
-
79952822990
-
Symptomatic management in multiple sclerosis
-
Samkoff LM, Goodman AD. Symptomatic management in multiple sclerosis. Neurol Clin. 2011;29:449-463.
-
(2011)
Neurol Clin
, vol.29
, pp. 449-463
-
-
Samkoff, L.M.1
Goodman, A.D.2
-
4
-
-
79956069870
-
Symptomatic therapy in multiple sclerosis: a review for a multimodal approach in clinical practice
-
de Sa JC, Airas L, Bartholome E, et al. Symptomatic therapy in multiple sclerosis: a review for a multimodal approach in clinical practice. Ther Adv Neurol Disord. 2011;4:139-168.
-
(2011)
Ther Adv Neurol Disord
, vol.4
, pp. 139-168
-
-
de Sa, J.C.1
Airas, L.2
Bartholome, E.3
-
5
-
-
84908440540
-
-
Ampyra [package insert]. Ardsley, NY: Acorda Therapeutics, Inc
-
Ampyra [package insert]. Ardsley, NY: Acorda Therapeutics, Inc; 2013.
-
(2013)
-
-
-
6
-
-
84908452952
-
-
Accessed August 30
-
Australian Government, Department of Health and Aging, Therapeutic Goods Administration. Australian Public Assessment Report for Fampridine. http://www.tga.gov.au/pdf/auspar/auspar-fampyra.pdf. Accessed August 30, 2012.
-
(2012)
Australian Public Assessment Report for Fampridine
-
-
-
7
-
-
84908412601
-
-
Accessed September 18
-
European Medicines Agency Committee for Medicinal Products for Human Use. Summary of Opinion (Initial Authorisation) for Fampyra (Fampridine). http://www.ema.europa.eu/docs/en_GB/document_library/Summary_of_opinion_-_Initial_authorisation/human/002097/WC500106531.pdf. Accessed September 18, 2012.
-
(2012)
Summary of Opinion (Initial Authorisation) for Fampyra (Fampridine)
-
-
-
8
-
-
0030989459
-
Quantitative assessment of sustained-release 4-aminopyridine for symptomatic treatment of multiple sclerosis
-
Schwid SR, Petrie MD, McDermott MP, Tierney DS, Mason DH, Goodman AD. Quantitative assessment of sustained-release 4-aminopyridine for symptomatic treatment of multiple sclerosis. Neurology. 1997;48:817-821.
-
(1997)
Neurology
, vol.48
, pp. 817-821
-
-
Schwid, S.R.1
Petrie, M.D.2
McDermott, M.P.3
Tierney, D.S.4
Mason, D.H.5
Goodman, A.D.6
-
9
-
-
71549172199
-
Steady-state pharmacokinetics and tolerability of orally administered fampridine sustained release 10-mg tablets in patients with multiple sclerosis: a 2-week, open-label, followup study
-
Vollmer T, Blight AR, Henney HR. Steady-state pharmacokinetics and tolerability of orally administered fampridine sustained release 10-mg tablets in patients with multiple sclerosis: a 2-week, open-label, followup study. Clin Ther. 2009;31:2215-2223.
-
(2009)
Clin Ther
, vol.31
, pp. 2215-2223
-
-
Vollmer, T.1
Blight, A.R.2
Henney, H.R.3
-
10
-
-
71549141975
-
Pharmacokinetics and tolerability of single escalating doses of fampridine sustained-release tablets in patients with multiple sclerosis: a phase I-II, open-label trial
-
Vollmer T, Henney HR. Pharmacokinetics and tolerability of single escalating doses of fampridine sustained-release tablets in patients with multiple sclerosis: a phase I-II, open-label trial. Clin Ther. 2009;31:2206-2214.
-
(2009)
Clin Ther
, vol.31
, pp. 2206-2214
-
-
Vollmer, T.1
Henney, H.R.2
-
11
-
-
60649090430
-
Sustained release of oral fampridine in multiple sclerosis: a randomised, double-blind, controlled trial
-
Goodman AD, Brown TR, Krupp L, et al. Sustained release of oral fampridine in multiple sclerosis: a randomised, double-blind, controlled trial. Lancet. 2009;373:732-738.
-
(2009)
Lancet
, vol.373
, pp. 732-738
-
-
Goodman, A.D.1
Brown, T.R.2
Krupp, L.3
-
12
-
-
78149478174
-
A phase 3 trial of extended release oral dalfampridine in multiple sclerosis
-
Goodman AD, Brown TR, Edwards KR, et al. A phase 3 trial of extended release oral dalfampridine in multiple sclerosis. Ann Neurol. 2010;68:494-502.
-
(2010)
Ann Neurol
, vol.68
, pp. 494-502
-
-
Goodman, A.D.1
Brown, T.R.2
Edwards, K.R.3
-
13
-
-
52949133688
-
Dose-comparison trial of sustained-release fampridine in multiple sclerosis
-
Goodman AD, Brown TR, Cohen JA, et al. Dose-comparison trial of sustained-release fampridine in multiple sclerosis. Neurology. 2008;71:1134-1141.
-
(2008)
Neurology
, vol.71
, pp. 1134-1141
-
-
Goodman, A.D.1
Brown, T.R.2
Cohen, J.A.3
-
14
-
-
0037435521
-
Measuring the impact of MS on walking ability: the 12-Item MS Walking Scale (MSWS-12)
-
Hobart JC, Riazi A, Lamping DL, Fitzpatrick R, Thompson AJ. Measuring the impact of MS on walking ability: the 12-Item MS Walking Scale (MSWS-12). Neurology. 2003;60:31-36.
-
(2003)
Neurology
, vol.60
, pp. 31-36
-
-
Hobart, J.C.1
Riazi, A.2
Lamping, D.L.3
Fitzpatrick, R.4
Thompson, A.J.5
-
15
-
-
0034724163
-
MS functional composite: relation to disease phenotype and disability strata
-
Kalkers NF, de Groot V, Lazeron RH, et al. MS functional composite: relation to disease phenotype and disability strata. Neurology. 2000;54:1233-1239.
-
(2000)
Neurology
, vol.54
, pp. 1233-1239
-
-
Kalkers, N.F.1
de Groot, V.2
Lazeron, R.H.3
-
16
-
-
0036783422
-
The Multiple Sclerosis Functional Composite; a new clinical outcome measure for multiple sclerosis clinical trials
-
Rudick RA, Cutter G, Reingold S. The Multiple Sclerosis Functional Composite; a new clinical outcome measure for multiple sclerosis clinical trials. Mult Scler. 2002;8:359-365.
-
(2002)
Mult Scler
, vol.8
, pp. 359-365
-
-
Rudick, R.A.1
Cutter, G.2
Reingold, S.3
-
17
-
-
0032919071
-
Development of a multiple sclerosis functional composite as a clinical trial outcome measure
-
Cutter GR, Baier ML, Rudick RA, et al. Development of a multiple sclerosis functional composite as a clinical trial outcome measure. Brain. 1999;122:871-882.
-
(1999)
Brain
, vol.122
, pp. 871-882
-
-
Cutter, G.R.1
Baier, M.L.2
Rudick, R.A.3
-
18
-
-
0034700986
-
Intrarater and interrater reliability of the MS functional composite outcome measure
-
Cohen JA, Fischer JS, Bolibrush DM, et al. Intrarater and interrater reliability of the MS functional composite outcome measure. Neurology. 2000;54:802-806.
-
(2000)
Neurology
, vol.54
, pp. 802-806
-
-
Cohen, J.A.1
Fischer, J.S.2
Bolibrush, D.M.3
-
19
-
-
0030692770
-
The measurement of ambulatory impairment in multiple sclerosis
-
Schwid SR, Goodman AD, Mattson DH, et al. The measurement of ambulatory impairment in multiple sclerosis. Neurology. 1997;49:1419-1424.
-
(1997)
Neurology
, vol.49
, pp. 1419-1424
-
-
Schwid, S.R.1
Goodman, A.D.2
Mattson, D.H.3
-
20
-
-
84855933857
-
Evaluating walking mobility in patients with multiple sclerosis: utility of instruments in clinical trials and clinical practice
-
Bethoux FA, Bennett SE. Evaluating walking mobility in patients with multiple sclerosis: utility of instruments in clinical trials and clinical practice. Int J MS Care. 2011;13:4-14.
-
(2011)
Int J MS Care
, vol.13
, pp. 4-14
-
-
Bethoux, F.A.1
Bennett, S.E.2
-
21
-
-
84857866698
-
Which walking capacity tests to use in multiple sclerosis? a multicentre study providing the basis for a core set
-
Gijbels D, Dalgas U, Romberg A, et al. Which walking capacity tests to use in multiple sclerosis? a multicentre study providing the basis for a core set. Mult Scler. 2011;18:364-371.
-
(2011)
Mult Scler
, vol.18
, pp. 364-371
-
-
Gijbels, D.1
Dalgas, U.2
Romberg, A.3
-
22
-
-
0033842378
-
The significant change for the Timed 25-foot Walk in the multiple sclerosis functional composite
-
Kaufman M, Moyer D, Norton J. The significant change for the Timed 25-foot Walk in the multiple sclerosis functional composite. Mult Scler. 2000;6:286-290.
-
(2000)
Mult Scler
, vol.6
, pp. 286-290
-
-
Kaufman, M.1
Moyer, D.2
Norton, J.3
-
23
-
-
0037161254
-
Quantitative functional measures in MS: what is a reliable change?
-
Schwid SR, Goodman AD, McDermott MP, Bever CF, Cook SD. Quantitative functional measures in MS: what is a reliable change? Neurology. 2002;58:1294-1296.
-
(2002)
Neurology
, vol.58
, pp. 1294-1296
-
-
Schwid, S.R.1
Goodman, A.D.2
McDermott, M.P.3
Bever, C.F.4
Cook, S.D.5
-
24
-
-
34250660553
-
Clinical impact of 20% worsening on Timed 25-foot Walk and 9-hole Peg Test in multiple sclerosis
-
Kragt JJ, van der Linden FA, Nielsen JM, Uitdehaag BM, Polman CH. Clinical impact of 20% worsening on Timed 25-foot Walk and 9-hole Peg Test in multiple sclerosis. Mult Scler. 2006;12:594-598.
-
(2006)
Mult Scler
, vol.12
, pp. 594-598
-
-
Kragt, J.J.1
van der Linden, F.A.2
Nielsen, J.M.3
Uitdehaag, B.M.4
Polman, C.H.5
-
25
-
-
77952851113
-
Outcome measurement in multiple sclerosis: detection of clinically relevant improvement
-
van Winsen LM, Kragt JJ, Hoogervorst EL, Polman CH, Uitdehaag BM. Outcome measurement in multiple sclerosis: detection of clinically relevant improvement. Mult Scler. 2010;16:604-610.
-
(2010)
Mult Scler
, vol.16
, pp. 604-610
-
-
van Winsen, L.M.1
Kragt, J.J.2
Hoogervorst, E.L.3
Polman, C.H.4
Uitdehaag, B.M.5
-
26
-
-
77955041173
-
Progression on the Multiple Sclerosis Functional Composite in multiple sclerosis: what is the optimal cut-off for the three components?
-
Bosma LV, Kragt JJ, Brieva L, et al. Progression on the Multiple Sclerosis Functional Composite in multiple sclerosis: what is the optimal cut-off for the three components? Mult Scler. 2010;16:862-867.
-
(2010)
Mult Scler
, vol.16
, pp. 862-867
-
-
Bosma, L.V.1
Kragt, J.J.2
Brieva, L.3
-
27
-
-
75949150955
-
Preliminary trial of carisoprodol in multiple sclerosis
-
Ashworth B. Preliminary trial of carisoprodol in multiple sclerosis. Practitioner. 1964;192:540-542.
-
(1964)
Practitioner
, vol.192
, pp. 540-542
-
-
Ashworth, B.1
-
28
-
-
0003998896
-
-
London, United Kingdom: Her Majesty's Stationery Office
-
Medical Research Council (MRC). Aids to the Investigation of Peripheral Nerve Injuries. London, United Kingdom: Her Majesty's Stationery Office; 1976.
-
(1976)
Aids to the Investigation of Peripheral Nerve Injuries
-
-
-
29
-
-
55249124510
-
Fampridine for MS responders: clinically relevant or hypothesis generating? [comment]
-
Kryscio RJ. Fampridine for MS responders: clinically relevant or hypothesis generating? [comment]. Neurology. 2008;71:1130-1131.
-
(2008)
Neurology
, vol.71
, pp. 1130-1131
-
-
Kryscio, R.J.1
-
30
-
-
84855916543
-
Minimally important clinical difference of the Timed 25-Foot Walk Test: results from a randomized controlled trial in patients with multiple sclerosis
-
Coleman CI, Sobieraj DM, Marinucci LN. Minimally important clinical difference of the Timed 25-Foot Walk Test: results from a randomized controlled trial in patients with multiple sclerosis. Curr Med Res Opin. 2012;28:49-56.
-
(2012)
Curr Med Res Opin
, vol.28
, pp. 49-56
-
-
Coleman, C.I.1
Sobieraj, D.M.2
Marinucci, L.N.3
-
31
-
-
78650105940
-
Prolonged-release fampridine for multiple sclerosis: was the effect on walking ability clinically significant? [abstract]
-
Hobart J. Prolonged-release fampridine for multiple sclerosis: was the effect on walking ability clinically significant? [abstract]. Mult Scler. 2010;(suppl 16):S72.
-
(2010)
Mult Scler
, pp. S72
-
-
Hobart, J.1
-
32
-
-
65749088247
-
Factors that influence adherence with disease-modifying therapy in MS
-
Treadaway K, Cutter G, Salter A, et al. Factors that influence adherence with disease-modifying therapy in MS. J Neurol. 2009;256: 568-576.
-
(2009)
J Neurol
, vol.256
, pp. 568-576
-
-
Treadaway, K.1
Cutter, G.2
Salter, A.3
-
33
-
-
84866512508
-
The MS Choices Survey: findings of a study assessing physician and patient perspectives on living with and managing multiple sclerosis
-
Rinon A, Buch M, Holley D, Verdun E. The MS Choices Survey: findings of a study assessing physician and patient perspectives on living with and managing multiple sclerosis. Patient Prefer Adherence. 2011;5:629-643.
-
(2011)
Patient Prefer Adherence
, vol.5
, pp. 629-643
-
-
Rinon, A.1
Buch, M.2
Holley, D.3
Verdun, E.4
-
34
-
-
80053535002
-
Diseasemodifying drug initiation patterns in commercially insured multiple sclerosis patients: a retrospective cohort study
-
Margolis JM, Fowler R, Johnson BH, Kassed CA, Kahler K. Diseasemodifying drug initiation patterns in commercially insured multiple sclerosis patients: a retrospective cohort study. BMC Neurol. 2011;11:122.
-
(2011)
BMC Neurol
, vol.11
, pp. 122
-
-
Margolis, J.M.1
Fowler, R.2
Johnson, B.H.3
Kassed, C.A.4
Kahler, K.5
-
35
-
-
79958863778
-
Dalfampridine: a brief review of its mechanism of action and efficacy as a treatment to improve walking in patients with multiple sclerosis
-
Dunn J, Blight A. Dalfampridine: a brief review of its mechanism of action and efficacy as a treatment to improve walking in patients with multiple sclerosis. Curr Med Res Opin. 2011;27:1415-1423.
-
(2011)
Curr Med Res Opin
, vol.27
, pp. 1415-1423
-
-
Dunn, J.1
Blight, A.2
|