Novel hydroxyapatite biomaterial covalently linked to raloxifene

International Journal of Immunopathology and Pharmacology

Volumn 27, Issue 3, 2014, Pages 437-444

  Meme L ^a   Santarelli, A ^a,b   Marzo, G ^c   Emanuelli, M ^a   Nocini, P F ^d   Bertossi, D ^d   Putignano, A ^a   Dioguardi, M ^e   Lo Muzio, L ^e   Bambini, F ^a,b  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b Italian National Institute for Research and Care on Aging   (Italy)

^c UNIVERSITY OF L'AQUILA   (Italy)

^d UNIVERSITY OF VERONA   (Italy)

^e UNIVERSITY OF FOGGIA   (Italy)

Author keywords

(3 aminopropyl) triethoxysilane; Covalent bond; Nanohydroxiapatite; Osteoblast; Raloxifene

Indexed keywords

3 AMINOPROPYLTRIETHOXYSILANE; HYDROXYAPATITE; NANOMATERIAL; RALOXIFENE; BIOMATERIAL;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; COVALENT BOND; DEVICE SAFETY; INFRARED SPECTROSCOPY; OSTEOBLAST; SCANNING ELECTRON MICROSCOPY; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; HUMAN; LETTER;

BIOCOMPATIBLE MATERIALS; CELL SURVIVAL; DURAPATITE; HUMANS; MICROSCOPY, ELECTRON, SCANNING; OSTEOBLASTS; RALOXIFENE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 84908396536     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463201402700315     Document Type: Article

References (39)

1. Boccaccini AR, Blaker JJ. Bioactive composite materials for tissue engineering scaffolds. Expert Rev Med Devices 2005; 2:303-17.
2. Helen W, Merry CL, Blaker JJ, Gough JE. Three- dimensional culture of annulus fibrosus cells within PDLLA/Bioglass composite foam scaffolds: Assessment of cell attachment, proliferation and extracellular matrix production. Biomaterials 2007; 28:2010-20.
3. Xu C, Wang Y, Yu X, et al. Evaluation of human mesenchymal stem cells response to biomimetic bioglass-collagen-hyaluronic acid- phosphatidylserine composite scaffolds for bone tissue engineering. J Biomed Mater Res A 2009; 88:264-73.
4. Barboza EP, Caula AL, Caula Fde O, et al. Effect ofrecombinant human bone morphogenetic protein-2 in an absorbable collagen sponge with space-providing biomaterials on the augmentation of chronic alveolar ridge defects. J Periodontol 2004; 75:702-8.
5. Sigurdsson TJ, Nygaard L, Tatakis DN, et al. Periodontal repair in dogs: evaluation of rhBMP-2 carriers. Int J Periodontics Restorative Dent 1996; 16:524-37.
6. Terheyden H, Jepsen S, Vogeler S, Tucker M, Rueger DC. Recombinant human osteogenic protein 1 in the rat mandibular augmentation model: differences in morphology of the newly formed bone are dependent on the type of carrier. Mund Kiefer Gesichtschir 1997; 1:272-5.
7. Gille J, Dorn B, Kekow J, Bruns J, Behrens P. Bone substitutes as carriers for transforming growth factor- beta(l) (TGF-beta(l)). Int Orthop 2002; 26:203-6.
8. Bambini F, Pellecchia M, Meme L, et al. Antiinflammatory cytokines in peri-implant soft tissues: A preliminary study on humans using cDNA microarray technology. Eur J Inflamm 2007; 5:121-7.
9. Bambini F, De-Stefano CA, Giannotti L, Meme L, Pellecchia M. Influence of biphosphonates on the integration process of endosseous implants evaluated using single photon emission computerized tomography (SPECT). Minerva Stomatol 2003; 52:331-8.
10. Greiner SH, Wildemann B, Back DA, et al. Local application of zoledronic acid incorporated in a poly(D, L-lactide)-coated implant accelerates fracture healing in rats. Acta Orthop 2008; 79:717-25.
11. Shi X, Wang Y, Ren L, Gong Y, Wang DA. Enhancing alendronate release from a novel PLGA/hydroxyapatite microspheric system for bone repairing applications. Pharm Res 2009; 26:422-30.
12. Srisubut S, Teerakapong A, Vattraphodes T, Taweechaisupapong S. Effect of local delivery of alendronate on bone formation in bioactive glass grafting in rats. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007; 104:e11-6.
13. Houshmand B, Rahimi H, Ghanavati F, Alisadr A, Eslami B. Boosting effect of bisphosphonates on osteoconductive materials: A histologic in vivo evaluation. J Periodontal Res 2007; 42:119-23.
14. Liu XM, Lee HT, Reinhardt RA, Marky LA, Wang D. Novel biomineral-binding cyclodextrins for controlled drug delivery in the oral cavity. J Control Release 2007; 122:54-62.
15. Garbuz DS, Hu Y, Kim WY, et al. Enhanced gap filling and osteoconduction associated with alendronate- calcium phosphate-coated porous tantalum. J Bone Joint Surg Am 2008; 90:1090-100.
16. Ahola M, Rich J, Kortesuo P, Kiesvaara J, Seppala J, Yli-Urpo A. In vitro evaluation of biodegradable epsilon-caprolactone-co-D, L-lactide/silica xerogel composites containing toremifene citrate. Int J Pharm 1999; 181:181-91.
17. Bambini F, Greci L, Meme L, et al. Raloxifene covalently bonded to titanium implants by interfacing with (3-aminopropyl)-triethoxysilane affects osteoblast-like cell gene expression. Int J Immunopathol Pharmacol 2006; 19:905-14.
18. Richelson LS, Wahner HW, Melton LJ 3rd, Riggs BL. Relative contributions of aging and estrogen deficiency to postmenopausal bone loss. N Engl J Med. 1984;311:1273-5.
19. Lindsay R, Hart DM, Aitken JM, MacDonald EB, Anderson JB, Clarke AC. Long-term prevention of postmenopausal osteoporosis by oestrogen. Evidence for an increased bone mass after delayed onset of oestrogen treatment. Lancet. 1976; 1:1038-41.
20. Lo-Muzio L, Santarelli A, Orsini G, Meme L, Mattioli-Belmonte M, De-Florio I, Gatto R, Bambini F. MG63 and MC3T3-E1 osteoblastic cell lines response to raloxifene. Eur J Inflamm 2013; 11:797-804.
21. Black LJ, Jones CD, Falcone JF. Antagonism of estrogen action with a new benzothiophene derived antiestrogen. Life Sci 1983; 32:1031-6.
22. Kumar V, Green S, Stack G, Berry M, Jin JR, Chambon P. Functional domains of the human estrogen receptor. Cell 1987; 51:941-51.
23. Sato M, McClintock C, Kim J, et al. Dual-energy x-ray absorptiometry of raloxifene effects on the lumbar vertebrae and femora of ovariectomized rats. J Bone Miner Res 1994; 9:715-24.
24. Evans G, Bryant HU, Magee D, Sato M, Turner RT. The effects of raloxifene on tibia histomorphometry in ovariectomized rats. Endocrinology 1994; 134:2283-8.
25. Webster TJ, Siegel RW, Bizios R. Osteoblast adhesion on nanophase ceramics. Biomaterials 1999; 20:1221-7.
26. Lepore S, Milillo L, Trotta T, et al. Adhesion and growth of osteoblast-like cells on laser-engineered porous titanium surface: Expression and localization of N-cadherin and (3-catenin. J Biol Regul Homeost Agents 2013;27:531-41.
27. Webster TJ, Ergun C, Doremus RH, Siegel RW, Bizios R. Specific proteins mediate enhanced osteoblast adhesion on nanophase ceramics. J Biomed Mater Res 2000;51:475-83.
28. Wei G, Ma PX. Structure and properties of nano- hydroxyapatite/polymer composite scaffolds for bone tissue engineering. Biomaterials 2004; 25:4749-57.
29. Santarelli A, Lo Russo L, Bambini F, Campisi G, Lo Muzio L. New perspectives in medical approach to therapy of head and neck squamous cell carcinoma. Minerva Stomatol 2009; 58:445-52.
30. Lo Muzio L, Sartini D, Santarelli A, et al. Expression and prognostic significance of apoptotic genes in oral squamous cell carcinoma. Mol Carcinog 2014; 53:264-71.
31. Bambini F, Santarelli A, Marzo G, Rubini C, Orsini G, Di Iorio D, Lo Russo L, Lo Muzio L. CD3 and CD20 expression in titanium vs zirconia peri-implant soft tissues: A human study. Eur J Inflamm 2013; 11:305-10.
32. Woo KM, Seo J, Zhang R, Ma PX. Suppression of apoptosis by enhanced protein adsorption on polymer/hydroxyapatite composite scaffolds. Biomaterials 2007; 28:2622-30.
33. Zhu W, Chen K, Lu W, et al. In vitro study of nano- HA/PLLA composite scaffold for rabbit BMSC differentiation under TGF-pi induction. In Vitro Cell Dev Biol Anim 2014; 50:214-20.
34. Busilacchi A, Gigante A, Mattioli-Belmonte M, Manzotti S, Muzzarelli RA. Chitosan stabilizes platelet growth factors and modulates stem cell differentiation toward tissue regeneration. Carbohydr Polym 2013; 98:665-76.
35. Tan R, She Z, Wang M, Yu X, Jin H, Feng Q. Repair of rat calvarial bone defects by controlled release of rhBMP-2 from an injectable bone regeneration composite. J Tissue Eng Regen Med 2012; 6:614-21.
36. Liu HC, ELL, Wang DS, Su F, Wu X, Shi ZP, Lv Y, Wang JZ. Reconstruction of alveolar bone defects using bone morphogenetic protein 2 mediated rabbit dental pulp stem cells seeded on nano- hydroxyapatite/collagen/poly(L-lactide). Tissue Eng Part A 2011; 17:2417-33.
37. Wang X, Song G, Lou T. Fabrication and characterization of nano-composite scaffold of PLLA/silane modified hydroxyapatite. Med Eng Phys 2010; 32:391-97.
38. Dupraz AM, de-Wijn JR, Meer SA, de-Groot K. Characterization of silane-treated hydroxyapatite powders for use as filler in biodegradable composites. J Biomed Mater Res 1996; 30:231-38.
39. Ravarian R, Wei H, Dehghani F. Improving the bioactivity of bioglass/(PMMA-co-MPMA) organic/inorganic hybrid. Conf Proc IEEE Eng Med Biol Soc 2011;2011:3593-6.