Effect of recombinant human bone morphogenetic protein-2 in an absorbable collagen sponge with space/providing biomaterials on the augmentation of chronic alveolar ridge defects

Journal of Periodontology

Volumn 75, Issue 5, 2004, Pages 702-708

  Porto Barboza, Eliane ^a,e   Caúla, André Luis ^a   de Oliveira Caúla, Fernanda ^b   Oliveira de Souza, Rogério ^a   Geolás Neto, Luiz ^a   Sorensen, Rachel G ^c   Li, X Jian ^c   Wikesjö, Ulf M E ^d  

^a FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^b Rio de Janeiro State Fire Department   (Brazil)

^c PFIZER INC   (United States)

^d TEMPLE UNIVERSITY   (United States)

^e NONE   (Brazil)

Author keywords

Alveolar ridge augmentation; Animal studies; Bone matrix; Bone regeneration; Glass, biologically active; Proteins, bone morphogenetic; Proteins, recombinant

Indexed keywords

BIOMATERIAL; COLLAGEN; DRUG CARRIER; GLASS; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2;

ALVEOLAR RIDGE; ANIMAL EUTHANASIA; ANIMAL TISSUE; ARTICLE; BONE BIOPSY; BONE DEFECT; BONE MATRIX; CONNECTIVE TISSUE; CONTROLLED STUDY; DOG; DRUG EFFICACY; ENCAPSULATION; FLUORESCENCE; HISTOPATHOLOGY; MALE; MICROSCOPY; MONITORING; NONHUMAN; OSSIFICATION;

EID: 3042658510     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2004.75.5.702     Document Type: Article

References (18)

1. Toriumi DM, Kotler HS, Luxenberg DP, Holtrop ME, Wang EA. Mandibular reconstruction with a recombinant bone-inducing factor. Functional, histologic, and biomechanical evaluation. Arch Otolaryngol Head Neck Surg 1991;117:1101-1112.
2. Boyne PJ. Animal studies of the application of rhBMP-2 in maxillofacial reconstruction. Bone 1996;19:83S-92S.
3. Boyne PJ, Nath R, Nakamura A. Human recombinant BMP-2 in osseous reconstruction of simulated cleft palate defects. Br J Oral Maxillofac Surg 1998;36:84-90.
4. Nevins M, Kirker-Head C, Nevins M, Wozney JA, Palmer R, Graham D. Bone formation and the goat maxillary sinus induced by absorbable collagen sponge implants impregnated with recombinant human bone morphogenetic protein-2. Int J Periodontics Restorative Dent 1996;16:8-19.
5. Hanisch O, Tatakis DN, Rohrer MD, Wöhrle PS, Wozney JM, Wikesjö UME. Bone formation and osseointegration stimulated by rhBMP-2 following subantral augmentation procedures in nonhuman primates. Int J Oral Maxillofac Implants 1997;12:785-792.
6. Ishikawa I, Kinoshita A, Oda S, Roongruanphol T. Regenerative therapy in periodontal diseases-Histological observations after implantation of rhBMP-2 in the surgically created periodontal defects in dogs. Dent Jpn 1994;31:141-146.
7. Sigurdsson TJ, Lee MB, Kubota K, Turek TJ, Wozney JM, Wikesjö UME. Periodontal repair in dogs: Recombinant human bone morphogenetic protein-2 significantly enhances periodontal regeneration. J Periodontol 1995;66:131-138.
8. Kinoshita A, Oda S, Takahashi K, Yokota S, Ishikawa I. Periodontal regeneration by application of recombinant human bone morphogenetic protein-2 to horizontal circumferential defects created by experimental periodontitis in beagle dogs. J Periodontol 1997;68:103-109.
9. Wikesjö UME, Guglielmoni PG, Promsudthi A, et al. Periodontal repair in dogs: Effect of rhBMP-2 concentration on regeneration of alveolar bone and periodontal attachment. J Clin Periodontol 1999;26:392-400.
10. Cochran DL, Schenk R, Buser D, Wozney JM, Jones AA. Recombinant human bone morphogenetic protein-2 stimulation of bone formation around endosseous dental implants. J Periodontol 1999;70:139-150.
11. Hanisch O, Tatakis DN, Boskovic MM, Rohrer MD, Wikesjö UME. Bone formation and reosseointegration in peri-implantitis defects following surgical implantation of rhBMP-2. Int J Oral Maxillofac Implants 1997;12:604-610.
12. Sigurdsson TJ, Fu E, Tatakis DN, Rohrer MD, Wikesjö UME. Bone morphogenetic protein-2 enhances peri-implant bone regeneration and osseointegration. Clin Oral Implants Res 1997;8:367-374.
13. Barboza EP, Leite Duarte ME, Geolás L, Sorensen RG, Riedel GE, Wikesjö UME. Ridge augmentation following implantation of recombinant human bone morphogenetic protein-2 in the dog. J Periodontol 2000;71:488-496.
14. Barboza EP. Regeneration of surgically reduced alveolar ridges utilizing demineralized freeze-dried bone cortical columns and membrane in dogs: A clinical and histological study. [Thesis]. Boston: Boston University; 1993.
15. Schmitz JP, Hollinger JO. The critical size defect as an experimental model for craniomandibulofacial non-unions. Clin Orthop 1986;205:299-308.
16. Sigurdsson TJ, Nygaard L, Tatakis DN, et al. Periodontal repair in dogs: Evaluation of rhBMP-2 carriers. Int J Periodontics Restorative Dent 1996;16:524-537.
17. Sigurdsson TJ, Nguyen S, Wikesjö UME. Alveolar ridge augmentation with rhBMP-2 and bone-to-implant contact in induced bone. Int J Periodontics Restorative Dent 2001;21:461-473.
18. Niederwanger M, Urist MR. Demineralized bone matrix supplied by bone banks for a carrier of recombinant human bone morphogenetic protein (rhBMP-2): A substitute for autogeneic bone grafts. J Oral Implantol 1996;22:210-215.