The search for a promising cell factory system for production of edible vaccine: Spirulina as a robust alternate to plants

Human Vaccines and Immunotherapeutics

Volumn 10, Issue 8, 2014, Pages 2497-2502

  Barzegari, Abolfazl ^a   Saeedi, Nazli ^a   Zarredar, Habib ^a   Barar, Jaleh ^a   Omidi, Yadollah ^a  

^a UNIVERSITY OF TABRIZ   (Iran)

Author keywords

Arthrospira; Plant edible vaccine; Probiotic; Spirulina; Vaccination

Indexed keywords

EDIBLE VACCINE;

BIOTECHNOLOGICAL PRODUCTION; COST EFFECTIVENESS ANALYSIS; DRUG PURIFICATION; DRUG SAFETY; DRUG STABILITY; HEALTH PROMOTION; HUMAN; IMMUNOMODULATION; MUCOSAL IMMUNITY; NONHUMAN; NOTE; NUTRIENT CONTENT; PLANT BIOTECHNOLOGY; SPIRULINA; VACCINE PRODUCTION; BIOTECHNOLOGY; GROWTH, DEVELOPMENT AND AGING; ISOLATION AND PURIFICATION; METABOLISM; PHARMACEUTICS; PROCEDURES;

BIOTECHNOLOGY; HUMANS; SPIRULINA; TECHNOLOGY, PHARMACEUTICAL; VACCINES, EDIBLE;

EID: 84908388692     PISSN: 21645515     EISSN: 2164554X     Source Type: Journal    
DOI: 10.4161/hv.29032     Document Type: Note

References (38)

1. Mason HS, Lam DM, Arntzen CJ. Expression of hepatitis B surface antigen in transgenic plants. Proc Natl Acad Sci U S A 1992; 89:11745-9; PMID:1465391; http://dx.doi.org/10.1073/pnas.89.24.11745
2. Khamsi R. Potatoes pack a punch against hepatitis B. news nature 2005;Available from: http://www.nature.com/news/2005/050214/full/news050214-2.html
3. Lycke N. Recent progress in mucosal vaccine development: potential and limitations. Nat Rev Immunol 2012; 12:592-605; PMID:22828912; http://dx.doi.org/10.1038/nri3251
4. Sharma M, Sood B. A banana or a syringe: journey to edible vaccines. World J Microbiol Biotechnol 2011; 27:471-7; http://dx.doi.org/10.1007/s11274-010-0481-9
5. Pelosi A, Shepherd R, Walmsley AM. Delivery of plant-made vaccines and therapeutics. Biotechnol Adv 2012; 30:440-8; PMID:21843627; http://dx.doi.org/10.1016/j.biotechadv.2011.07.018
6. Mishra N, Gupta PN, Khatri K, Goyal AK, Vyas SP. Edible vaccines: A new approach to oral immunization. Indian J Biotechnol 2008; 7:283-94
7. Obembe OO, Popoola JO, Leelavathi S, Reddy SV. Advances in plant molecular farming. Biotechnol Adv 2011; 29:210-22; PMID:21115109; http://dx.doi.org/10.1016/j.biotechadv.2010.11.004
8. Lin LL. Cartagena Protocol on Biosafety. Biosafety First 2007:407.
9. Steidler L, Hans W, Schotte L, Neirynck S, Obermeier F, Falk W, Fiers W, Remaut E. Treatment of murine colitis by Lactococcus lactis secreting interleukin-10. Science 2000; 289:1352-5; PMID:10958782; http://dx.doi.org/10.1126/science.289.5483.1352
10. Stadler BM, Vogel M, Germond E-J, Fritsche R. Lactic acid bacteria as agents for treating and preventing allergy. Google Patents, 2007.
11. Grangette C, Müller-Alouf H, Goudercourt D, Geoffroy M-C, Turneer M, Mercenier A. Mucosal immune responses and protection against tetanus toxin after intranasal immunization with recombinant Lactobacillus plantarum. Infect Immun 2001; 69:1547-53; PMID:11179325; http://dx.doi.org/10.1128/IAI.69.3.1547-1553.2001
12. Barzegari A, Saei AA. Designing probiotics with respect to the native microbiome. Future Microbiol 2012; 7:571-5; PMID:22568713; http://dx.doi.org/10.2217/fmb.12.37
13. Syvanen M. Evolutionary implications of horizontal gene transfer. Annu Rev Genet 2012; 46:341-58; PMID:22934638; http://dx.doi.org/10.1146/annurev-genet-110711-155529
14. Cummins J, Ho M-W. Genetically modified probiotics should be banned. Microb Ecol Health Dis 2005; 17:66-8; http://dx.doi.org/10.1080/08910600510044480
15. Belay A, Ota Y, Miyakawa K, Shimamatsu H. Current knowledge on potential health benefits of Spirulina. J Appl Phycol 1993; 5:235-41; http://dx.doi.org/10.1007/BF00004024
16. Koru E. Earth Food Spirulina (Arthrospira): Production and Quality Standarts. In: El-Samragy Y, ed. Food Additive. Turkey: InTech, 2012:191-202.
17. Ravi M, De SL, Azharuddin S, Paul SF. The beneficial effects of Spirulina focusing on its immunomodulatory and antioxidant properties. Nutr Diet Suppl 2010; 2:73-83
18. Saei AA, Omidi AA, Barzegari A. Screening and genetic manipulation of green organisms for establishment of biological life support systems in space. Bioengineered 2013; 4:65-71; PMID:22992434; http://dx.doi.org/10.4161/bioe.22286
19. Phang SM, Miah MS, Yeoh BG, Hashim MA. Spirulina cultivation in digested sago starch factory wastewater. J Appl Phycol 2000; 12:395-400; http://dx.doi.org/10.1023/A:1008157731731
20. Wu LC, Ho JA, Shieh MC, Lu IW. Antioxidant and antiproliferative activities of Spirulina and Chlorella water extracts. J Agric Food Chem 2005; 53:4207-12; PMID:15884862; http://dx.doi.org/10.1021/jf0479517
21. Tobón-Velasco JC, Palafox-Sánchez V, Mendieta L, García E, Santamaría A, Chamorro-Cevallos G, Limón ID. Antioxidant effect of Spirulina (Arthrospira) maxima in a neurotoxic model caused by 6-OHDA in the rat striatum. J Neural Transm 2013; 120:1179-89; PMID:23430275; http://dx.doi.org/10.1007/s00702-013-0976-2
22. Lee EH, Park JE, Choi YJ, Huh KB, Kim WY. A randomized study to establish the effects of spirulina in type 2 diabetes mellitus patients. Nutr Res Pract 2008; 2:295-300; PMID:20016733; http://dx.doi.org/10.4162/nrp.2008.2.4.295
23. Wang Y, Chang CF, Chou J, Chen HL, Deng X, Harvey BK, Cadet JL, Bickford PC. Dietary supplementation with blueberries, spinach, or spirulina reduces ischemic brain damage. Exp Neurol 2005; 193:75-84; PMID:15817266; http://dx.doi.org/10.1016/j.expneurol.2004.12.014
24. Khan Z, Bhadouria P, Bisen PS. Nutritional and therapeutic potential of Spirulina. Curr Pharm Biotechnol 2005; 6:373-9; PMID:16248810; http://dx.doi.org/10.2174/138920105774370607
25. Yamani E, Kaba-Mebri J, Mouala C, Gresenguet G, Rey JL. [Use of spirulina supplement for nutritional management of HIV-infected patients: study in Bangui, Central African Republic]. Med Trop (Mars) 2009; 69:66-70; PMID:19499738
26. Barrón LB, Torres-Valencia MJ, Chamorro-Cevallos G, Zúñiga-Estrada A. Spirulina in human nutrition and health. In: Gershwin ME, Belay A, eds. Spirulina as an Antiviral Agent. New York: CRC Press,Taylor & Francis, 2008:227-40.
27. Watanuki H, Ota K, Tassakka ACMA, Kato T, Sakai M. Immunostimulant effects of dietary〈i〉 Spirulina platensis〈/i〉 on carp,〈i〉 Cyprinus carpio〈/i〉. Aquaculture 2006; 258:157-63; http://dx.doi.org/10.1016/j.aquaculture.2006.05.003
28. Das P, Mishra A, Das M. Spirulina: the superfood and medicine. Algal biotechnology: new vistas 2010:62-76.
29. Pradhan J, Das BK, Sahu S, Marhual NP, Swain AK, Mishra BK, et al. Traditional antibacterial activity of freshwater microalga Spirulina platensis to aquatic pathogens. Aquacult Res 2012; 43:1287-95; http://dx.doi.org/10.1111/j.1365-2109.2011.02932.x
30. Pentón-Rol G, Marín-Prida J, Pardo-Andreu G, Martínez-Sánchez G, Acosta-Medina EF, Valdivia-Acosta A, Lagumersindez-Denis N, Rodríguez-Jiménez E, Llópiz-Arzuaga A, López-Saura PA, et al. C-Phycocyanin is neuroprotective against global cerebral ischemia/reperfusion injury in gerbils. Brain Res Bull 2011; 86:42-52; PMID:21669260; http://dx.doi.org/10.1016/j.brainresbull.2011.05.016
31. Chervonsky AV. Intestinal commensals: influence on immune system and tolerance to pathogens. Curr Opin Immunol 2012; 24:255-60; PMID:22445718; http://dx.doi.org/10.1016/j.coi.2012.03.002
32. ZHOU Y-c, HU Y-x, MA Z. Animals Study on Spirulina as an Adjuvant Blood Lipid Lowering and Immune Function Enhancing Agent [J]. Practical Preventive Medicine 2006; 2:033.
33. Volpi C, Fallarino F, Pallotta MT, Bianchi R, Vacca C, Belladonna ML, Orabona C, De Luca A, Boon L, Romani L, et al. High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway. Nat Commun 2013; 4:1852; PMID:23673637; http://dx.doi.org/10.1038/ncomms2874
34. Hirahashi T, Matsumoto M, Hazeki K, Saeki Y, Ui M, Seya T. Activation of the human innate immune system by Spirulina: augmentation of interferon production and NK cytotoxicity by oral administration of hot water extract of Spirulina platensis. Int Immunopharmacol 2002; 2:423-34; PMID:11962722; http://dx.doi.org/10.1016/S1567-5769(01)00166-7
35. Hironobu W, Kazuki O, Asmi C, Tassakka T, Masahiro S. Immunostimulant effects of dietary Spirulina platensis on carp, Cyprinus carpio. Aquaculture 2006; 258:157-63; http://dx.doi.org/10.1016/j.aquaculture.2006.05.003
36. Ahsan M, Habib B, Parvin M, Huntington TC, Hasan MR. A review on culture, production and use of spirulina as food for humans and feeds for domestic animals. FAO, 2008.
37. Ravi M, De SL, Azharuddin S, Paul SFD. The beneficial effects of Spirulina focusing on its immunomodulatory and antioxidant properties. Nutrition and Dietary Supplements 2010; 2.
38. Walker TL, Purton S, Becker DK, Collet C. Microalgae as bioreactors. Plant Cell Rep 2005; 24:629-41; PMID:16136314; http://dx.doi.org/10.1007/s00299-005-0004-6