HIV Acquisition Is Associated with Increased Antimicrobial Peptides and Reduced HIV Neutralizing IgA in the Foreskin Prepuce of Uncircumcised Men

PLoS Pathogens

Volumn 10, Issue 10, 2014, Pages

  Hirbod, Taha ^a   Kong, Xiangrong ^b   Kigozi, Godgrey ^c   Ndyanabo, Anthony ^c   Serwadda, David ^c,d   Prodger, Jessica L ^e   Tobian, Aaron A ^b   Nalugoda, Fred ^c   Wawer, Maria J ^a,c   Shahabi, Kamnoosh ^e   Rojas, Olga L ^e   Gommerman, Jennifer L ^e   Broliden, Kristina ^a   Kaul, Rupert ^e   Gray, Ronald H ^a,c  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c RAKAI HEALTH SCIENCES PROGRAM   (Uganda)

^d MAKERERE UNIVERSITY SCHOOL OF PUBLIC HEALTH   (Uganda)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA DEFENSIN; BETA DEFENSIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; IMMUNOGLOBULIN A; LACTOFERRIN; POLYPEPTIDE ANTIBIOTIC AGENT; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; SYNDECAN 1; ANTIINFECTIVE AGENT; NEUTRALIZING ANTIBODY;

ADOLESCENT; ADULT; ARTICLE; CASE CONTROL STUDY; CIRCUMCISION; CONTROLLED STUDY; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNOFLUORESCENCE MICROSCOPY; MAJOR CLINICAL STUDY; MALE; PREPUCE; PROSPECTIVE STUDY; PROTEIN EXPRESSION; SEROCONVERSION; VIRUS NEUTRALIZATION; HETEROSEXUALITY; HIV INFECTIONS; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOLOGY; MIDDLE AGED; RANDOMIZED CONTROLLED TRIAL; UGANDA; YOUNG ADULT;

ADOLESCENT; ADULT; ANTI-INFECTIVE AGENTS; ANTIBODIES, NEUTRALIZING; CIRCUMCISION, MALE; FORESKIN; HETEROSEXUALITY; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOGLOBULIN A; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; UGANDA; YOUNG ADULT;

EID: 84908347225     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004416     Document Type: Article

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