Lamins: The structure and protein complexes

Current Opinion in Cell Biology

Volumn 32, Issue , 2015, Pages 7-12

  Gruenbaum, Yosef ^a   Medalia, Ohad ^b,c  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; LAMIN; LAMIN A; LAMIN B; CHROMATIN;

CAENORHABDITIS ELEGANS; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS MEMBRANE; ELECTRON TOMOGRAPHY; HUMAN; IN VITRO STUDY; NONHUMAN; NUCLEAR LAMINA; NUCLEAR PORE COMPLEX; PROTEIN ASSEMBLY; PROTEIN FOLDING; PROTEIN STRUCTURE; REVIEW; SCANNING ELECTRON MICROSCOPY; X RAY CRYSTALLOGRAPHY; XENOPUS LAEVIS; ANIMAL; CELL NUCLEUS; CHEMISTRY; CHROMATIN; GENETICS; METABOLISM; MUTATION;

ANIMALS; CELL NUCLEUS; CHROMATIN; HUMANS; LAMINS; MUTATION; NUCLEAR ENVELOPE;

EID: 84908338160     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2014.09.009     Document Type: Review

References (43)

1. Stuurman N., Heins S., Aebi U. Nuclear lamins: their structure, assembly, and interactions. J Struct Biol 1998, 122:42-66.
2. Erber A., Riemer D., Hofemeister H., Bovenschulte M., Stick R., Panopoulou G., Lehrach H., Weber K. Characterization of the Hydra lamin and its gene: a molecular phylogeny of metazoan lamins. J Mol Evol 1999, 49:260-271.
3. Butin-Israeli V., Adam S.A., Goldman A.E., Goldman R.D. Nuclear lamin functions and disease. Trends Genet 2012, 28:464-471.
4. Parry D.A., Conway J.F., Steinert P.M. Structural studies on lamin. Similarities and differences between lamin and intermediate-filament proteins. Biochem J 1986, 238:305-308.
5. Krüger A., Batsios P., Baumann O., Luckert E., Schwarz H., Stick R., Meyer I., Gräf R. Characterization of NE81, the first lamin-like nucleoskeleton protein in a unicellular organism. Mol Biol Cell 2012, 23:360-370.
6. Fawcett D.W. On the occurrence of a fibrous lamina on the inner aspect of the nuclear envelope in certain cells of vertebrates. Am J Anat 1966, 119:129-145.
7. Aebi U., Cohn J., Buhle L., Gerace L. The nuclear lamina is a meshwork of intermediate-type filaments. Nature 1986, 323:560-564.
8. Harapin J., Eibauer M., Medalia O. Structural analysis of supramolecular assemblies by cryo-electron tomography. Structure 2013, 21:1522-1530.
9. Hofemeister H., Kuhn C., Franke W.W., Weber K., Stick R. Conservation of the gene structure and membrane-targeting signals of germ cell-specific lamin LIII in amphibians and fish. Eur J Cell Biol 2002, 81:51-60.
10. Funkhouser W.K., Niethammer M., Carson J.L., Burns K.A., Knowles M.R., Leigh M.W., Zariwala M.A., Funkhouser W.K. A new tool improves diagnostic test performance for transmission EM evaluation of axonemal dynein arms. Ultrastruct Pathol 2014, 38:248-255.
11. Shimi T., Pfleghaar K., Kojima S., Pack C.G., Solovei I., Goldman A.E., Adam S.A., Shumaker D.K., Kinjo M., Cremer T., et al. The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription. Genes Dev 2008, 22:3409-3421.
12. Kapinos L.E., Burkhard P., Herrmann H., Aebi U., Strelkov S.V. Simultaneous formation of right- and left-handed anti-parallel coiled-coil interfaces by a coil2 fragment of human lamin A. J Mol Biol 2011, 408:135-146.
13. Ben-Harush K., Wiesel N., Frenkiel-Krispin D., Moeller D., Soreq E., Aebi U., Herrmann H., Gruenbaum Y., Medalia O. The supramolecular organization of the C. elegans nuclear lamin filament. J Mol Biol 2009, 386:1392-1402.
14. Krimm I., Ostlund C., Gilquin B., Couprie J., Hossenlopp P., Mornon J.P., Bonne G., Courvalin J.C., Worman H.J., Zinn-Justin S. The Ig-like structure of the C-terminal domain of lamin a/c, mutated in muscular dystrophies, cardiomyopathy, and partial lipodystrophy. Structure 2002, 10:811-823.
15. Dhe-Paganon S., Werner E.D., Chi Y.I., Shoelson S.E. Structure of the globular tail of nuclear lamin. J Biol Chem 2002, 277:17381-17384.
16. Kapinos L.E., Schumacher J., Mücke N., Machaidze G., Burkhard P., Aebi U., Strelkov S.V., Herrmann H. Characterization of the head-to-tail overlap complexes formed by human lamin A, B1 and B2 'half-minilamin' dimers. J Mol Biol 2010, 396:719-731.
17. Grossmann E., Dahan I., Stick R., Goldberg M.W., Gruenbaum Y., Medalia O. Filament assembly of ectopically expressed C. elegans lamin within Xenopus oocytes. J Struct Biol 2012, 177:113-118.
18. Goldman A.E., Moir R.D., Montag L.M., Stewart M., Goldman R.D. Pathway of incorporation of microinjected lamin A into the nuclear envelope. J Cell Biol 1992, 119:725-735.
19. Moir R.D., Montag L.M., Goldman R.D. Dynamic properties of nuclear lamins: lamin B is associated with sites of DNA replication. J Cell Biol 1994, 125:1201-1212.
20. Dyer J.A., Kill I.R., Pugh G., Quinlan R.A., Lane E.B., Hutchison C.J. Cell cycle changes in A-type lamin associations detected in human dermal fibroblasts using monoclonal antibodies. Chromosome Res 1997, 383-394.
21. Dechat T., Korbei B., Vaughan O.A., Vlcek S., Hutchison C.J., Foisner R. Lamina-associated polypeptide 2alpha binds intranuclear A-type lamins. J Cell Sci 2000, 113:3473-3484.
22. Liu J., Rolef-Ben Shahar T., Riemer D., Spann P., Treinin M., Weber K., Fire A., Gruenbaum Y. Essential roles for Caenorhabditis elegans lamin gene in nuclear organization, cell cycle progression, and spatial organization of nuclear pore complexes. Mol Biol Cell 2000, 11:3937-3947.
23. Naetar N., Korbei B., Kozlov S., Kerenyi M.A., Dorner D., Kral R., Gotic I., Fuchs P., Cohen T., Bittner R., et al. Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation. Nat Cell Biol 2008, 10:1341-1348.
24. Kolb T., Maass K., Hergt M., Aebi U., Herrmann H. Lamin A and lamin C form homodimers and coexist in higher complex forms both in the nucleoplasmic fraction and in the lamina of cultured human cells. Nucleus 2011, 2:425-433.
25. Kochin V., Shimi T., Torvaldson E., Adam S.A., Goldman A., Pack C.G., Melo-Cardenas J., Imanishi S.Y., Goldman R.D., Eriksson J.E. Interphase phosphorylation of lamin A. J Cell Sci 2014, 127:2683-2696.
26. Shumaker D.K., Solimando L., Sengupta K., Shimi T., Adam S.A., Grunwald A., Strelkov S.V., Aebi U., Cardoso M.C., Goldman R.D. The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication. J Cell Biol 2008, 181:269-280.
27. Moir R.D., Spann T.P., Lopez-Soler R.I., Yoon M., Goldman A.E., Khuon S., Goldman R.D. The dynamics of the nuclear lamins during the cell cycle-relationship between structure and function. J Struct Biol 2000, 129:324-334.
28. Broers J.L., Machiels B.M., van Eys G.J., Kuijpers H.J., Manders E.M., van Driel R., Ramaekers F.C. Dynamics of the nuclear lamina as monitored by GFP-tagged A-type lamins. J Cell Sci 1999, 112:3463-3475.
29. Wiesel N., Mattout A., Melcer S., Melamed-Book N., Herrmann H., Medalia O., Aebi U., Gruenbaum Y. Laminopathic mutations interfere with the assembly, localization and dynamics of nuclear lamins. Proc Natl Acad Sci USA 2008, 105:180-185.
30. Kaminsky R., Denison C., Bening-Abu-Shach U., Chisholm A.D., Gygi S.P., Broday L. SUMO regulates the assembly and function of a cytoplasmic intermediate filament protein in C. elegans. Dev Cell 2009, 17:724-735.
31. Markiewicz E., Dechat T., Foisner R., Quinlan R.A., Hutchison C.J. Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein. Mol Biol Cell 2002, 13:4401-4413.
32. Mahen R., Hattori H., Lee M., Sharma P., Jeyasekharan A.D., Venkitaraman A.R. A-type lamins maintain the positional stability of DNA damage repair foci in mammalian nuclei. PLoS ONE 2013, 8:e61893.
33. de Las Heras J.I., Meinke P., Batrakou D.G., Srsen V., Zuleger N., Kerr A.R., Schirmer E.C. Tissue specificity in the nuclear envelope supports its functional complexity. Nucleus 2013, 4:460-477.
34. Wilson K.L., Foisner R. Lamin-binding Proteins. Cold Spring Harb Perspect Biol 2010, 2:a000554.
35. Gruenbaum Y., Margalit A., Goldman R.D., Shumaker D.K., Wilson K.L. The nuclear lamina comes of age. Nat Rev Mol Cell Biol 2005, 6:21-31.
36. Padan R., Nainudel E.S., Goitein R., Fainsod A., Gruenbaum Y. Isolation and characterization of the Drosophila nuclear envelope otefin cDNA. J Biol Chem 1990, 265:7808-7813.
37. Lin F., Blake D.L., Callebaut I., Skerjanc I.S., Holmer L., McBurney M.W., Paulin-Levasseur M., Worman H.J. MAN1, an inner nuclear membrane protein that shares the LEM domain with lamina-associated polypeptide 2 and emerin. J Biol Chem 2000, 275:4840-4847.
38. Malone C.J., Fixsen W.D., Horvitz H.R., Han M. UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development. Development 1999, 126:3171-3181.
39. Lee K.K., Starr D., Liu J., Cohen M., Han M., Wilson K., Gruenbaum Y. Lamin-dependent localization of UNC-84, a protein required for nuclear migration in C. elegans. Mol Biol Cell 2002, 13:892-901.
40. Tzur Y., Wilson K.L., Gruenbaum Y. SUN-domain proteins: 'Velcro' that links the nucleoskeleton to the cytoskeleton. Nat Rev Cell Mol Biol 2006, 7:782-788.
41. Roux K.J., Kim D.I., Burke B. BioID: a screen for protein-protein interactions. Curr Protoc Protein Sci 2013, 74:19.23.11-19.23.14.
42. Roux K.J., Kim D.I., Raida M., Burke B. A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells. J Cell Biol 2012, 196:801-810.
43. Swift J., Ivanovska I.L., Buxboim A., Harada T., Dingal P.C., Pinter J., Pajerowski J.D., Spinler K.R., Shin J.W., Tewari M., et al. Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science 2013, 341:1240104.