Hollow microspheres based on - Folic acid modified - Hydroxypropyl Cellulose and synthetic multi-responsive bio-copolymer for targeted cancer therapy: Controlled release of daunorubicin, in vitro and in vivo studies

Journal of Colloid and Interface Science

Volumn 435, Issue , 2014, Pages 171-181

  Metaxa, Aikaterini Foteini ^a   Efthimiadou, Eleni K ^a   Boukos, Nikos ^a   Fragogeorgi, Eirini A ^b,c   Loudos, George ^c   Kordas, George ^a  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^b Biomolecular Physics Laboratory   (Greece)

^c UNIVERSITY OF WEST ATTICA   (Greece)

Author keywords

Cytotoxicity; Daunorubicin; Drug delivery systems; Folic acid; HPC; IC50; Microspheres; MTT assay; Multi responsive carriers; Polysaccharides

Indexed keywords

MICROSPHERES; POLYSACCHARIDES;

DAUNORUBICIN; DRUG DELIVERY SYSTEM; FOLIC ACIDS; HPC; MTT ASSAYS; MULTI-RESPONSIVE;

CYTOTOXICITY;

COPOLYMER; DAUNORUBICIN; ETHYLENE GLYCOL DIMETHACRYLATE; FOLATE RECEPTOR; FOLIC ACID; GLUTATHIONE; HYDROXYPROPYLMETHYLCELLULOSE; METHACRYLIC ACID; MICROSPHERE; N (2 HYDROXYPROPYL)METHACRYLAMIDE; N,N' [DISULFANEDIYLBIS(ETHANE 2,1 DIYL))BIS(2 METHYLACRYLAMIDE); POLYSACCHARIDE; TECHNETIUM 99M; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CELLULOSE; DELAYED RELEASE FORMULATION; DOXORUBICIN; HYDROXYPROPYLCELLULOSE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL LINE; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED RELEASE FORMULATION; CYTOTOXICITY; DISTILLATION; DRUG CONJUGATION; DRUG RELEASE; ENCAPSULATION; HUMAN; HUMAN CELL; HYPERTHERMIA; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; NANOTECHNOLOGY; POLYMERIZATION; PRECIPITATION; SCANNING ELECTRON MICROSCOPY; SCINTIGRAPHY; STRUCTURE ANALYSIS; SYNTHESIS; TRANSMISSION ELECTRON MICROSCOPY; ANALOGS AND DERIVATIVES; ANIMAL; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; DRUG EFFECTS; FEMALE; MOUSE; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CELLULOSE; DELAYED-ACTION PREPARATIONS; DOXORUBICIN; DRUG DELIVERY SYSTEMS; FEMALE; FOLIC ACID; HUMANS; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MOLECULAR STRUCTURE;

EID: 84908317930     PISSN: 00219797     EISSN: 10957103     Source Type: Journal    
DOI: 10.1016/j.jcis.2014.08.001     Document Type: Article

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