메뉴 건너뛰기




Volumn 92, Issue 2, 2014, Pages 123-132

Adrenocortical carcinoma: The management of metastatic disease

Author keywords

Adrenocortical carcinoma; Metastatic disease; Targeted therapies; Therapeutics

Indexed keywords

ADRENERGIC RECEPTOR BLOCKING AGENT; ANTINEOPLASTIC AGENT; BETA CATENIN; CAPECITABINE; CISPLATIN; CIXUTUMUMAB; DOVITINIB; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ETOPOSIDE; FIGITUMUMAB; FLUOROURACIL; GEMCITABINE; IMATINIB; MAMMALIAN TARGET OF RAPAMYCIN; MITOTANE; POLO LIKE KINASE 1; SOMATOMEDIN C RECEPTOR; SORAFENIB; SUNITINIB; TEMSIROLIMUS; VASCULOTROPIN; WNT PROTEIN; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS;

EID: 84908311835     PISSN: 10408428     EISSN: 18790461     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2014.05.009     Document Type: Review
Times cited : (38)

References (97)
  • 1
    • 0016756332 scopus 로고
    • Third national cancer survey: incidence data
    • 1-454
    • Third national cancer survey: incidence data. National Cancer Institute Monograph 1975, 41(March):i-x. 1-454.
    • (1975) National Cancer Institute Monograph , vol.41 , Issue.MARCH , pp. 1-10
  • 2
    • 33646593777 scopus 로고    scopus 로고
    • Extent of disease at presentation and outcome for adrenocortical carcinoma: have we made progress?
    • Kebebew E., Reiff E., Duh Q.Y., Clark O.H., McMillan A. Extent of disease at presentation and outcome for adrenocortical carcinoma: have we made progress?. World J Surg 2006, 30(May (5)):872-878.
    • (2006) World J Surg , vol.30 , Issue.MAY 5 , pp. 872-878
    • Kebebew, E.1    Reiff, E.2    Duh, Q.Y.3    Clark, O.H.4    McMillan, A.5
  • 3
  • 4
    • 33646869990 scopus 로고    scopus 로고
    • Mortality rate of adrenocortical tumors in children under 15 years of age in Curitiba, Brazil
    • Pianovski M.A., Maluf E.M., de Carvalho D.S., et al. Mortality rate of adrenocortical tumors in children under 15 years of age in Curitiba, Brazil. Pediatr Blood Cancer 2006, 47(July (1)):56-60.
    • (2006) Pediatr Blood Cancer , vol.47 , Issue.JULY 1 , pp. 56-60
    • Pianovski, M.A.1    Maluf, E.M.2    de Carvalho, D.S.3
  • 5
    • 30744441388 scopus 로고    scopus 로고
    • Penetrance of adrenocortical tumours associated with the germline TP53 R337H mutation
    • Figueiredo B.C., Sandrini R., Zambetti G.P., et al. Penetrance of adrenocortical tumours associated with the germline TP53 R337H mutation. J Med Genet 2006, 43(January (1)):91-96.
    • (2006) J Med Genet , vol.43 , Issue.JANUARY 1 , pp. 91-96
    • Figueiredo, B.C.1    Sandrini, R.2    Zambetti, G.P.3
  • 6
    • 84870758773 scopus 로고    scopus 로고
    • Targeting estrogen receptor-alpha reduces adrenocortical cancer (ACC) cell growth in vitro and in vivo: potential therapeutic role of selective estrogen receptor modulators (SERMs) for ACC treatment
    • Sirianni R., Zolea F., Chimento A., et al. Targeting estrogen receptor-alpha reduces adrenocortical cancer (ACC) cell growth in vitro and in vivo: potential therapeutic role of selective estrogen receptor modulators (SERMs) for ACC treatment. J Clin Endocrinol Metab 2012, 97(December (12)):E2238-E2250.
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.DECEMBER 12 , pp. E2238-E2250
    • Sirianni, R.1    Zolea, F.2    Chimento, A.3
  • 7
    • 0025248241 scopus 로고
    • Clinical features of adrenocortical carcinoma, prognostic factors, and the effect of mitotane therapy
    • Luton J.P., Cerdas S., Billaud L., et al. Clinical features of adrenocortical carcinoma, prognostic factors, and the effect of mitotane therapy. N Engl J Med 1990, 322(April (17)):1195-1201.
    • (1990) N Engl J Med , vol.322 , Issue.APRIL 17 , pp. 1195-1201
    • Luton, J.P.1    Cerdas, S.2    Billaud, L.3
  • 8
    • 58149381997 scopus 로고    scopus 로고
    • Preclinical targeting of the type I insulin-like growth factor receptor in adrenocortical carcinoma
    • Barlaskar F.M., Spalding A.C., Heaton J.H., et al. Preclinical targeting of the type I insulin-like growth factor receptor in adrenocortical carcinoma. J Clin Endocrinol Metab 2009, 94(January (1)):204-212.
    • (2009) J Clin Endocrinol Metab , vol.94 , Issue.JANUARY 1 , pp. 204-212
    • Barlaskar, F.M.1    Spalding, A.C.2    Heaton, J.H.3
  • 9
    • 84887235975 scopus 로고    scopus 로고
    • Adrenocortical carcinoma is a lynch syndrome-associated cancer
    • Raymond V.M., Everett J.N., Furtado L.V., et al. Adrenocortical carcinoma is a lynch syndrome-associated cancer. J Clin Oncol 2013, 31(August (24)):3012-3018.
    • (2013) J Clin Oncol , vol.31 , Issue.AUGUST 24 , pp. 3012-3018
    • Raymond, V.M.1    Everett, J.N.2    Furtado, L.V.3
  • 10
    • 27644431904 scopus 로고    scopus 로고
    • Molecular genetics of adrenocortical tumours, from familial to sporadic diseases
    • Libe R., Bertherat J. Molecular genetics of adrenocortical tumours, from familial to sporadic diseases. Eur J Endocrinol 2005, 153(October (4)):477-487.
    • (2005) Eur J Endocrinol , vol.153 , Issue.OCTOBER 4 , pp. 477-487
    • Libe, R.1    Bertherat, J.2
  • 11
    • 0036920488 scopus 로고    scopus 로고
    • The molecular pathogenesis of hereditary and sporadic adrenocortical and adrenomedullary tumors
    • Koch C.A., Pacak K., Chrousos G.P. The molecular pathogenesis of hereditary and sporadic adrenocortical and adrenomedullary tumors. J Clin Endocrinol Metab 2002, 87(December (12)):5367-5384.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.DECEMBER 12 , pp. 5367-5384
    • Koch, C.A.1    Pacak, K.2    Chrousos, G.P.3
  • 12
    • 84896720825 scopus 로고    scopus 로고
    • Genetics and epigenetics of adrenocortical tumors
    • [Epub 2013 Nov 9]
    • Lerario A.M., Moraitis A., Hammer G.D. Genetics and epigenetics of adrenocortical tumors. Mol Cell Endocrinol 2014, 386(April (1-2)):67-84. [Epub 2013 Nov 9]. 10.1016/j.mce.2013.10.028.
    • (2014) Mol Cell Endocrinol , vol.386 , Issue.1-2 APRIL , pp. 67-84
    • Lerario, A.M.1    Moraitis, A.2    Hammer, G.D.3
  • 13
    • 84888267331 scopus 로고    scopus 로고
    • Adrenocortical carcinoma: clinical outcomes and prognosis of 330 patients at a tertiary care center
    • [Print 2013 Dec]
    • Ayala-Ramirez M., Jasim S., Feng L., et al. Adrenocortical carcinoma: clinical outcomes and prognosis of 330 patients at a tertiary care center. Eur J Endocrinol 2013, 169(October (6)):891-899. [Print 2013 Dec]. 10.1530/EJE-13-0519.
    • (2013) Eur J Endocrinol , vol.169 , Issue.OCTOBER 6 , pp. 891-899
    • Ayala-Ramirez, M.1    Jasim, S.2    Feng, L.3
  • 15
    • 80053312970 scopus 로고    scopus 로고
    • Contemporary management of adrenocortical carcinoma
    • Zini L., Porpiglia F., Fassnacht M. Contemporary management of adrenocortical carcinoma. Eur Urol 2011, 60(November (5)):1055-1065.
    • (2011) Eur Urol , vol.60 , Issue.NOVEMBER 5 , pp. 1055-1065
    • Zini, L.1    Porpiglia, F.2    Fassnacht, M.3
  • 16
    • 79957577222 scopus 로고    scopus 로고
    • Adrenocortical carcinoma: a clinician's update
    • Fassnacht M., Libe R., Kroiss M., Allolio B. Adrenocortical carcinoma: a clinician's update. Nat Rev Endocrinol 2011, 7(June (6)):323-335.
    • (2011) Nat Rev Endocrinol , vol.7 , Issue.JUNE 6 , pp. 323-335
    • Fassnacht, M.1    Libe, R.2    Kroiss, M.3    Allolio, B.4
  • 17
    • 13144260715 scopus 로고    scopus 로고
    • Role of reoperation in recurrence of adrenal cortical carcinoma: results from 188 cases collected in the Italian National Registry for Adrenal Cortical Carcinoma
    • Bellantone R., Ferrante A., Boscherini M., et al. Role of reoperation in recurrence of adrenal cortical carcinoma: results from 188 cases collected in the Italian National Registry for Adrenal Cortical Carcinoma. Surgery 1997, 122(December (6)):1212-1218.
    • (1997) Surgery , vol.122 , Issue.DECEMBER 6 , pp. 1212-1218
    • Bellantone, R.1    Ferrante, A.2    Boscherini, M.3
  • 18
    • 0033396346 scopus 로고    scopus 로고
    • Long-term survival after complete resection and repeat resection in patients with adrenocortical carcinoma
    • Schulick R.D., Brennan M.F. Long-term survival after complete resection and repeat resection in patients with adrenocortical carcinoma. Ann Surg Oncol 1999, 6(December (8)):719-726.
    • (1999) Ann Surg Oncol , vol.6 , Issue.DECEMBER 8 , pp. 719-726
    • Schulick, R.D.1    Brennan, M.F.2
  • 19
    • 84859884713 scopus 로고    scopus 로고
    • Operative management for recurrent and metastatic adrenocortical carcinoma
    • Datrice N.M., Langan R.C., Ripley R.T., et al. Operative management for recurrent and metastatic adrenocortical carcinoma. J Surg Oncol 2012, 105(June (7)):709-713.
    • (2012) J Surg Oncol , vol.105 , Issue.JUNE 7 , pp. 709-713
    • Datrice, N.M.1    Langan, R.C.2    Ripley, R.T.3
  • 20
    • 0027051533 scopus 로고
    • An eleven-year experience with adrenocortical carcinoma
    • [discussion 970-961]
    • Pommier R.F., Brennan M.F. An eleven-year experience with adrenocortical carcinoma. Surgery 1992, 112(December (6)):963-970. [discussion 970-961].
    • (1992) Surgery , vol.112 , Issue.DECEMBER 6 , pp. 963-970
    • Pommier, R.F.1    Brennan, M.F.2
  • 21
    • 84872055357 scopus 로고    scopus 로고
    • The role of surgery in the management of recurrent adrenocortical carcinoma
    • Erdogan I., Deutschbein T., Jurowich C., et al. The role of surgery in the management of recurrent adrenocortical carcinoma. J Clin Endocrinol Metab 2013, 98(January (1)):181-191.
    • (2013) J Clin Endocrinol Metab , vol.98 , Issue.JANUARY 1 , pp. 181-191
    • Erdogan, I.1    Deutschbein, T.2    Jurowich, C.3
  • 22
    • 84865024540 scopus 로고    scopus 로고
    • Resection of adrenocortical carcinoma liver metastasis: is it justified?
    • Gaujoux S., Al-Ahmadie H., Allen P.J., et al. Resection of adrenocortical carcinoma liver metastasis: is it justified?. Ann Surg Oncol 2012, 19(August (8)):2643-2651.
    • (2012) Ann Surg Oncol , vol.19 , Issue.AUGUST 8 , pp. 2643-2651
    • Gaujoux, S.1    Al-Ahmadie, H.2    Allen, P.J.3
  • 23
    • 84872076027 scopus 로고    scopus 로고
    • A retrospective cohort analysis of the efficacy of adjuvant radiotherapy after primary surgical resection in patients with adrenocortical carcinoma
    • Habra M.A., Ejaz S., Feng L., et al. A retrospective cohort analysis of the efficacy of adjuvant radiotherapy after primary surgical resection in patients with adrenocortical carcinoma. J Clin Endocrinol Metab 2013, 98(January (1)):192-197.
    • (2013) J Clin Endocrinol Metab , vol.98 , Issue.JANUARY 1 , pp. 192-197
    • Habra, M.A.1    Ejaz, S.2    Feng, L.3
  • 26
    • 84862501220 scopus 로고    scopus 로고
    • German adrenocortical carcinoma registry, Surgical therapy results and follow-up treatment
    • Reibetanz J., Kroiss M., Deutschbein T., et al. German adrenocortical carcinoma registry, Surgical therapy results and follow-up treatment. Chirurg 2012, 83(June (6)):528-535.
    • (2012) Chirurg , vol.83 , Issue.JUNE 6 , pp. 528-535
    • Reibetanz, J.1    Kroiss, M.2    Deutschbein, T.3
  • 27
    • 84907110243 scopus 로고
    • Radiation therapy of adrenal cortical carcinoma
    • Percarpio B., Knowlton A.H. Radiation therapy of adrenal cortical carcinoma. Acta Radiol Ther Phys Biol 1976, 15(August (4)):288-292.
    • (1976) Acta Radiol Ther Phys Biol , vol.15 , Issue.AUGUST 4 , pp. 288-292
    • Percarpio, B.1    Knowlton, A.H.2
  • 28
    • 0025778455 scopus 로고
    • Radiation therapy for adjunctive treatment of adrenal cortical carcinoma
    • Markoe A.M., Serber W., Micaily B., Brady L.W. Radiation therapy for adjunctive treatment of adrenal cortical carcinoma. Am J Clin Oncol 1991, 14(April (2)):170-174.
    • (1991) Am J Clin Oncol , vol.14 , Issue.APRIL 2 , pp. 170-174
    • Markoe, A.M.1    Serber, W.2    Micaily, B.3    Brady, L.W.4
  • 29
    • 0018759572 scopus 로고
    • Adrenal cortical carcinoma: a clinical and pathologic study of 49 cases
    • King D.R., Lack E.E. Adrenal cortical carcinoma: a clinical and pathologic study of 49 cases. Cancer 1979, 44(July (1)):239-244.
    • (1979) Cancer , vol.44 , Issue.JULY 1 , pp. 239-244
    • King, D.R.1    Lack, E.E.2
  • 31
    • 67649622025 scopus 로고    scopus 로고
    • Radiotherapy in adrenocortical carcinoma
    • Polat B., Fassnacht M., Pfreundner L., et al. Radiotherapy in adrenocortical carcinoma. Cancer 2009, 115(July (13)):2816-2823.
    • (2009) Cancer , vol.115 , Issue.JULY 13 , pp. 2816-2823
    • Polat, B.1    Fassnacht, M.2    Pfreundner, L.3
  • 32
    • 45849101318 scopus 로고    scopus 로고
    • Mitotane increases the radiotherapy inhibitory effect and induces G2-arrest in combined treatment on both H295R and SW13 adrenocortical cell lines
    • Cerquetti L., Bucci B., Marchese R., et al. Mitotane increases the radiotherapy inhibitory effect and induces G2-arrest in combined treatment on both H295R and SW13 adrenocortical cell lines. Endocr Relat Cancer 2008, 15(June (2)):623-634.
    • (2008) Endocr Relat Cancer , vol.15 , Issue.JUNE 2 , pp. 623-634
    • Cerquetti, L.1    Bucci, B.2    Marchese, R.3
  • 33
    • 0037302792 scopus 로고    scopus 로고
    • Radiofrequency ablation of adrenal tumors and adrenocortical carcinoma metastases
    • Wood B.J., Abraham J., Hvizda J.L., Alexander H.R., Fojo T. Radiofrequency ablation of adrenal tumors and adrenocortical carcinoma metastases. Cancer 2003, 97(February (3)):554-560.
    • (2003) Cancer , vol.97 , Issue.FEBRUARY 3 , pp. 554-560
    • Wood, B.J.1    Abraham, J.2    Hvizda, J.L.3    Alexander, H.R.4    Fojo, T.5
  • 34
    • 1642366687 scopus 로고    scopus 로고
    • Adrenal neoplasms: CT-guided radiofrequency ablation--preliminary results
    • Mayo-Smith W.W., Dupuy D.E. Adrenal neoplasms: CT-guided radiofrequency ablation--preliminary results. Radiology 2004, 231(April (1)):225-230.
    • (2004) Radiology , vol.231 , Issue.APRIL 1 , pp. 225-230
    • Mayo-Smith, W.W.1    Dupuy, D.E.2
  • 35
    • 63449132667 scopus 로고    scopus 로고
    • A twelve-year experience with adrenal cortical carcinoma in a single institution: long-term survival after surgical treatment and transcatheter arterial embolization
    • Soga H., Takenaka A., Ooba T., et al. A twelve-year experience with adrenal cortical carcinoma in a single institution: long-term survival after surgical treatment and transcatheter arterial embolization. Urol Int 2009, 82(2):222-226.
    • (2009) Urol Int , vol.82 , Issue.2 , pp. 222-226
    • Soga, H.1    Takenaka, A.2    Ooba, T.3
  • 36
    • 77957823233 scopus 로고    scopus 로고
    • Transcatheter arterial chemoembolization for liver metastases in patients with adrenocortical carcinoma
    • Cazejust J., De Baere T., Auperin A., et al. Transcatheter arterial chemoembolization for liver metastases in patients with adrenocortical carcinoma. J Vasc Interv Radiol 2010, 21(October (10)):1527-1532.
    • (2010) J Vasc Interv Radiol , vol.21 , Issue.OCTOBER 10 , pp. 1527-1532
    • Cazejust, J.1    De Baere, T.2    Auperin, A.3
  • 37
    • 0036569569 scopus 로고    scopus 로고
    • A phase II trial of combination chemotherapy and surgical resection for the treatment of metastatic adrenocortical carcinoma: continuous infusion doxorubicin, vincristine, and etoposide with daily mitotane as a P-glycoprotein antagonist
    • Abraham J., Bakke S., Rutt A., et al. A phase II trial of combination chemotherapy and surgical resection for the treatment of metastatic adrenocortical carcinoma: continuous infusion doxorubicin, vincristine, and etoposide with daily mitotane as a P-glycoprotein antagonist. Cancer 2002, 94(May (9)):2333-2343.
    • (2002) Cancer , vol.94 , Issue.MAY 9 , pp. 2333-2343
    • Abraham, J.1    Bakke, S.2    Rutt, A.3
  • 38
    • 53749087386 scopus 로고    scopus 로고
    • Systemic chemotherapy for adrenocortical carcinoma: comparative responses to conventional first-line therapies
    • Fareau G.G., Lopez A., Stava C., Vassilopoulou-Sellin R. Systemic chemotherapy for adrenocortical carcinoma: comparative responses to conventional first-line therapies. Anticancer Drugs 2008, 19(July (6)):637-644.
    • (2008) Anticancer Drugs , vol.19 , Issue.JULY 6 , pp. 637-644
    • Fareau, G.G.1    Lopez, A.2    Stava, C.3    Vassilopoulou-Sellin, R.4
  • 39
    • 0028208020 scopus 로고
    • Optimal treatment of adrenocortical carcinoma with mitotane: results in a consecutive series of 96 patients
    • Haak H.R., Hermans J., van de Velde C.J., et al. Optimal treatment of adrenocortical carcinoma with mitotane: results in a consecutive series of 96 patients. Br J Cancer 1994, 69(May (5)):947-951.
    • (1994) Br J Cancer , vol.69 , Issue.MAY 5 , pp. 947-951
    • Haak, H.R.1    Hermans, J.2    van de Velde, C.J.3
  • 40
    • 0033331698 scopus 로고    scopus 로고
    • Comment - is there a role for low doses of mitotane (o,p'-DDD) as adjuvant therapy in adrenocortical carcinoma?
    • Barzon L., Fallo F., Sonino N., Daniele O., Boscaro M. Comment - is there a role for low doses of mitotane (o,p'-DDD) as adjuvant therapy in adrenocortical carcinoma?. J Clin Endocrinol Metab 1999, 84(April (4)):1488-1489.
    • (1999) J Clin Endocrinol Metab , vol.84 , Issue.APRIL 4 , pp. 1488-1489
    • Barzon, L.1    Fallo, F.2    Sonino, N.3    Daniele, O.4    Boscaro, M.5
  • 41
    • 0027190328 scopus 로고
    • Impact of adjuvant mitotane on the clinical course of patients with adrenocortical cancer
    • Vassilopoulou-Sellin R., Guinee V.F., Klein M.J., et al. Impact of adjuvant mitotane on the clinical course of patients with adrenocortical cancer. Cancer 1993, 71(May (10)):3119-3123.
    • (1993) Cancer , vol.71 , Issue.MAY 10 , pp. 3119-3123
    • Vassilopoulou-Sellin, R.1    Guinee, V.F.2    Klein, M.J.3
  • 42
    • 0001224922 scopus 로고
    • Chemotherapy of adrenocortical cancer with o,p' DDD
    • Bergenstal D.M.H.R., Lipsett M.B., et al. Chemotherapy of adrenocortical cancer with o,p' DDD. Ann Intern Med 1960, 53:672-682.
    • (1960) Ann Intern Med , vol.53 , pp. 672-682
    • Bergenstal, D.M.H.R.1    Lipsett, M.B.2
  • 43
    • 0033788018 scopus 로고    scopus 로고
    • Clinical results of the use of mitotane for adrenocortical carcinoma
    • Kasperlik-Zaluska A.A. Clinical results of the use of mitotane for adrenocortical carcinoma. Braz J Med Biol Res 2000, 33(October (10)):1191-1196.
    • (2000) Braz J Med Biol Res , vol.33 , Issue.OCTOBER 10 , pp. 1191-1196
    • Kasperlik-Zaluska, A.A.1
  • 44
    • 0034917097 scopus 로고    scopus 로고
    • Adrenocortical carcinomas: surgical trends and results of a 253-patient series from the French Association of Endocrine Surgeons study group
    • Icard P., Goudet P., Charpenay C., et al. Adrenocortical carcinomas: surgical trends and results of a 253-patient series from the French Association of Endocrine Surgeons study group. World J Surg 2001, 25(July (7)):891-897.
    • (2001) World J Surg , vol.25 , Issue.JULY 7 , pp. 891-897
    • Icard, P.1    Goudet, P.2    Charpenay, C.3
  • 45
    • 0035878781 scopus 로고    scopus 로고
    • Therapy of the adrenocortical carcinoma with Lysodren (o,p'-DDD). Therapeutic management by monitoring o,p'-DDD blood levels
    • Heilmann P., Wagner P., Nawroth P.P., Ziegler R. Therapy of the adrenocortical carcinoma with Lysodren (o,p'-DDD). Therapeutic management by monitoring o,p'-DDD blood levels. Med Klin 2001, 96(July (7)):371-377.
    • (2001) Med Klin , vol.96 , Issue.JULY 7 , pp. 371-377
    • Heilmann, P.1    Wagner, P.2    Nawroth, P.P.3    Ziegler, R.4
  • 46
    • 34249999500 scopus 로고    scopus 로고
    • Adjuvant mitotane treatment for adrenocortical carcinoma
    • Terzolo M., Angeli A., Fassnacht M., et al. Adjuvant mitotane treatment for adrenocortical carcinoma. N Engl J Med 2007, 356(June (23)):2372-2380.
    • (2007) N Engl J Med , vol.356 , Issue.JUNE 23 , pp. 2372-2380
    • Terzolo, M.1    Angeli, A.2    Fassnacht, M.3
  • 47
    • 79956306619 scopus 로고    scopus 로고
    • Plasma concentrations of o,p'DDD, o,p'DDA, and o,p'DDE as predictors of tumor response to mitotane in adrenocortical carcinoma: results of a retrospective ENSATT multicenter study
    • Hermsen I.G., Fassnacht M., Terzolo M., et al. Plasma concentrations of o,p'DDD, o,p'DDA, and o,p'DDE as predictors of tumor response to mitotane in adrenocortical carcinoma: results of a retrospective ENSATT multicenter study. J Clin Endocrinol Metab 2011, 96(June (6)):1844-1851.
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.JUNE 6 , pp. 1844-1851
    • Hermsen, I.G.1    Fassnacht, M.2    Terzolo, M.3
  • 48
    • 0033387698 scopus 로고    scopus 로고
    • Changes in neoplastic cell features and sensitivity to mitotane during mitotane-induced remission in a patient with recurrent, metastatic adrenocortical carcinoma
    • Seki M., Nomura K., Hirohara D., et al. Changes in neoplastic cell features and sensitivity to mitotane during mitotane-induced remission in a patient with recurrent, metastatic adrenocortical carcinoma. Endocr Relat Cancer 1999, 6(December (4)):529-533.
    • (1999) Endocr Relat Cancer , vol.6 , Issue.DECEMBER 4 , pp. 529-533
    • Seki, M.1    Nomura, K.2    Hirohara, D.3
  • 49
    • 0036860302 scopus 로고    scopus 로고
    • Use of a topoisomerase I inhibitor (irinotecan, CPT-11) in metastatic adrenocortical carcinoma
    • Baudin E., Docao C., Gicquel C., et al. Use of a topoisomerase I inhibitor (irinotecan, CPT-11) in metastatic adrenocortical carcinoma. Ann Oncol 2002, 13(November (11)):1806-1809.
    • (2002) Ann Oncol , vol.13 , Issue.NOVEMBER 11 , pp. 1806-1809
    • Baudin, E.1    Docao, C.2    Gicquel, C.3
  • 50
    • 0021289017 scopus 로고
    • The treatment of adrenocortical carcinoma with o,p'-DDD: prognostic implications of serum level monitoring
    • van Slooten H., Moolenaar A.J., van Seters A.P., Smeenk D. The treatment of adrenocortical carcinoma with o,p'-DDD: prognostic implications of serum level monitoring. Eur J Cancer Clin Oncol 1984, 20(January (1)):47-53.
    • (1984) Eur J Cancer Clin Oncol , vol.20 , Issue.JANUARY 1 , pp. 47-53
    • van Slooten, H.1    Moolenaar, A.J.2    van Seters, A.P.3    Smeenk, D.4
  • 51
    • 84866628998 scopus 로고    scopus 로고
    • Adrenal cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
    • 131-8
    • Berruti A., Baudin E., Gelderblom H., et al. Adrenal cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 2012, 23(October (Suppl. 7)):vii. 131-8.
    • (2012) Ann Oncol , vol.23 , Issue.OCTOBER SUPPL. 7 , pp. 7
    • Berruti, A.1    Baudin, E.2    Gelderblom, H.3
  • 52
    • 84856101843 scopus 로고    scopus 로고
    • High-dose mitotane strategy in adrenocortical carcinoma: prospective analysis of plasma mitotane measurement during the first 3 months of follow-up
    • Mauclere-Denost S., Leboulleux S., Borget I., et al. High-dose mitotane strategy in adrenocortical carcinoma: prospective analysis of plasma mitotane measurement during the first 3 months of follow-up. Eur J Endocrinol 2012, 166(February (2)):261-268.
    • (2012) Eur J Endocrinol , vol.166 , Issue.FEBRUARY 2 , pp. 261-268
    • Mauclere-Denost, S.1    Leboulleux, S.2    Borget, I.3
  • 53
    • 34249996792 scopus 로고    scopus 로고
    • Adjuvant mitotane therapy of adrenal cancer - use and controversy
    • Schteingart D.E. Adjuvant mitotane therapy of adrenal cancer - use and controversy. N Engl J Med 2007, 356(June (23)):2415-2418.
    • (2007) N Engl J Med , vol.356 , Issue.JUNE 23 , pp. 2415-2418
    • Schteingart, D.E.1
  • 54
    • 84872085592 scopus 로고    scopus 로고
    • Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5alpha-reductase, explaining the need for personalized glucocorticoid and androgen replacement
    • Chortis V., Taylor A.E., Schneider P., et al. Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5alpha-reductase, explaining the need for personalized glucocorticoid and androgen replacement. J Clin Endocrinol Metab 2013, 98(January (1)):161-171.
    • (2013) J Clin Endocrinol Metab , vol.98 , Issue.JANUARY 1 , pp. 161-171
    • Chortis, V.1    Taylor, A.E.2    Schneider, P.3
  • 55
    • 0015373407 scopus 로고
    • Treatment of adrenocortical carcinoma with o,p'-DDD
    • Hoffman D.L., Mattox V.R. Treatment of adrenocortical carcinoma with o,p'-DDD. Med Clin N Am 1972, 56(July (4)):999-1012.
    • (1972) Med Clin N Am , vol.56 , Issue.JULY 4 , pp. 999-1012
    • Hoffman, D.L.1    Mattox, V.R.2
  • 56
    • 58249103034 scopus 로고    scopus 로고
    • Prospective evaluation of mitotane toxicity in adrenocortical cancer patients treated adjuvantly
    • Daffara F., De Francia S., Reimondo G., et al. Prospective evaluation of mitotane toxicity in adrenocortical cancer patients treated adjuvantly. Endocr Relat Cancer 2008, 15(December (4)):1043-1053.
    • (2008) Endocr Relat Cancer , vol.15 , Issue.DECEMBER 4 , pp. 1043-1053
    • Daffara, F.1    De Francia, S.2    Reimondo, G.3
  • 57
    • 0034918563 scopus 로고    scopus 로고
    • Cytotoxic treatment of adrenocortical carcinoma
    • Ahlman H., Khorram-Manesh A., Jansson S., et al. Cytotoxic treatment of adrenocortical carcinoma. World J Surg 2001, 25(July (7)):927-933.
    • (2001) World J Surg , vol.25 , Issue.JULY 7 , pp. 927-933
    • Ahlman, H.1    Khorram-Manesh, A.2    Jansson, S.3
  • 58
    • 77953564914 scopus 로고    scopus 로고
    • Gemcitabine plus metronomic 5-fluorouracil or capecitabine as a second-/third-line chemotherapy in advanced adrenocortical carcinoma: a multicenter phase II study
    • Sperone P., Ferrero A., Daffara F., et al. Gemcitabine plus metronomic 5-fluorouracil or capecitabine as a second-/third-line chemotherapy in advanced adrenocortical carcinoma: a multicenter phase II study. Endocr Relat Cancer 2010, 17(June (2)):445-453.
    • (2010) Endocr Relat Cancer , vol.17 , Issue.JUNE 2 , pp. 445-453
    • Sperone, P.1    Ferrero, A.2    Daffara, F.3
  • 59
    • 0034162574 scopus 로고    scopus 로고
    • Phase II evaluation of cisplatin and etoposide followed by mitotane at disease progression in patients with locally advanced or metastatic adrenocortical carcinoma: a Southwest Oncology Group Study
    • Williamson S.K., Lew D., Miller G.J., Balcerzak S.P., Baker L.H., Crawford E.D. Phase II evaluation of cisplatin and etoposide followed by mitotane at disease progression in patients with locally advanced or metastatic adrenocortical carcinoma: a Southwest Oncology Group Study. Cancer 2000, 88(March (5)):1159-1165.
    • (2000) Cancer , vol.88 , Issue.MARCH 5 , pp. 1159-1165
    • Williamson, S.K.1    Lew, D.2    Miller, G.J.3    Balcerzak, S.P.4    Baker, L.H.5    Crawford, E.D.6
  • 60
    • 0032533913 scopus 로고    scopus 로고
    • Mitotane associated with etoposide, doxorubicin, and cisplatin in the treatment of advanced adrenocortical carcinoma. Italian Group for the Study of Adrenal Cancer
    • Berruti A., Terzolo M., Pia A., Angeli A., Dogliotti L. Mitotane associated with etoposide, doxorubicin, and cisplatin in the treatment of advanced adrenocortical carcinoma. Italian Group for the Study of Adrenal Cancer. Cancer 1998, 83(November (10)):2194-2200.
    • (1998) Cancer , vol.83 , Issue.NOVEMBER 10 , pp. 2194-2200
    • Berruti, A.1    Terzolo, M.2    Pia, A.3    Angeli, A.4    Dogliotti, L.5
  • 61
    • 0033767891 scopus 로고    scopus 로고
    • Streptozocin and o,p'DDD in the treatment of adrenocortical cancer patients: long-term survival in its adjuvant use
    • Khan T.S., Imam H., Juhlin C., et al. Streptozocin and o,p'DDD in the treatment of adrenocortical cancer patients: long-term survival in its adjuvant use. Ann Oncol 2000, 11(October (10)):1281-1287.
    • (2000) Ann Oncol , vol.11 , Issue.OCTOBER 10 , pp. 1281-1287
    • Khan, T.S.1    Imam, H.2    Juhlin, C.3
  • 62
    • 84861888600 scopus 로고    scopus 로고
    • Combination chemotherapy in advanced adrenocortical carcinoma
    • Fassnacht M., Terzolo M., Allolio B., et al. Combination chemotherapy in advanced adrenocortical carcinoma. N Engl J Med 2012, 366(June (23)):2189-2197.
    • (2012) N Engl J Med , vol.366 , Issue.JUNE 23 , pp. 2189-2197
    • Fassnacht, M.1    Terzolo, M.2    Allolio, B.3
  • 63
    • 84878580813 scopus 로고    scopus 로고
    • Treatment with docetaxel and cisplatin in advanced adrenocortical carcinoma, a phase II study
    • Urup T., Pawlak W.Z., Petersen P.M., Pappot H., Rorth M., Daugaard G. Treatment with docetaxel and cisplatin in advanced adrenocortical carcinoma, a phase II study. Br J Cancer 2013, 108(May (10)):1994-1997.
    • (2013) Br J Cancer , vol.108 , Issue.MAY 10 , pp. 1994-1997
    • Urup, T.1    Pawlak, W.Z.2    Petersen, P.M.3    Pappot, H.4    Rorth, M.5    Daugaard, G.6
  • 64
    • 83555178501 scopus 로고    scopus 로고
    • Metronomic therapy concepts in the management of adrenocortical carcinoma
    • Berruti A., Sperone P., Bellini E., et al. Metronomic therapy concepts in the management of adrenocortical carcinoma. Horm Cancer 2011, 2(December (6)):378-384.
    • (2011) Horm Cancer , vol.2 , Issue.DECEMBER 6 , pp. 378-384
    • Berruti, A.1    Sperone, P.2    Bellini, E.3
  • 65
    • 84884397988 scopus 로고    scopus 로고
    • Cytotoxic activity of gemcitabine, alone or in combination with mitotane, in adrenocortical carcinoma cell lines
    • [Epub 2013 Sep 7]
    • Germano A., Rapa I., Volante M., et al. Cytotoxic activity of gemcitabine, alone or in combination with mitotane, in adrenocortical carcinoma cell lines. Mol Cell Endocrinol 2014, 382(January (1)):1-7. [Epub 2013 Sep 7]. 10.1016/j.mce.2013.08.023.
    • (2014) Mol Cell Endocrinol , vol.382 , Issue.JANUARY 1 , pp. 1-7
    • Germano, A.1    Rapa, I.2    Volante, M.3
  • 66
    • 79960349342 scopus 로고    scopus 로고
    • Renal cell carcinoma
    • Choueiri T.K. Renal cell carcinoma. Hematol Oncol Clin N Am 2011, 25(August (4)):xiii-xiv.
    • (2011) Hematol Oncol Clin N Am , vol.25 , Issue.AUGUST 4 , pp. 13-14
    • Choueiri, T.K.1
  • 67
    • 77955618680 scopus 로고    scopus 로고
    • Updates on novel therapies for metastatic renal cell carcinoma
    • Courtney K.D., Choueiri T.K. Updates on novel therapies for metastatic renal cell carcinoma. Ther Adv Med Oncol 2010, 2(May (3)):209-219.
    • (2010) Ther Adv Med Oncol , vol.2 , Issue.MAY 3 , pp. 209-219
    • Courtney, K.D.1    Choueiri, T.K.2
  • 68
    • 67649246190 scopus 로고    scopus 로고
    • Nonclinical safety evaluation of sunitinib: a potent inhibitor of VEGF, PDGF, KIT, FLT3, and RET receptors
    • Patyna S., Arrigoni C., Terron A., et al. Nonclinical safety evaluation of sunitinib: a potent inhibitor of VEGF, PDGF, KIT, FLT3, and RET receptors. Toxicol Pathol 2008, 36(December (7)):905-916.
    • (2008) Toxicol Pathol , vol.36 , Issue.DECEMBER 7 , pp. 905-916
    • Patyna, S.1    Arrigoni, C.2    Terron, A.3
  • 69
    • 77956382293 scopus 로고    scopus 로고
    • Endocrine side effects of broad-acting kinase inhibitors
    • Lodish M.B., Stratakis C.A. Endocrine side effects of broad-acting kinase inhibitors. Endocr Relat Cancer 2010, 17(September (3)):R233-R244.
    • (2010) Endocr Relat Cancer , vol.17 , Issue.SEPTEMBER 3 , pp. R233-R244
    • Lodish, M.B.1    Stratakis, C.A.2
  • 70
    • 84867254773 scopus 로고    scopus 로고
    • Sunitinib inhibits cell proliferation and alters steroidogenesis by down-regulation of HSD3B2 in adrenocortical carcinoma cells
    • Kroiss M., Reuss M., Kuhner D., et al. Sunitinib inhibits cell proliferation and alters steroidogenesis by down-regulation of HSD3B2 in adrenocortical carcinoma cells. Front Endocrinol 2011, 2:27.
    • (2011) Front Endocrinol , vol.2 , pp. 27
    • Kroiss, M.1    Reuss, M.2    Kuhner, D.3
  • 71
    • 84867255648 scopus 로고    scopus 로고
    • Sunitinib in refractory adrenocortical carcinoma: a phase II, single-arm, open-label trial
    • Kroiss M., Quinkler M., Johanssen S., et al. Sunitinib in refractory adrenocortical carcinoma: a phase II, single-arm, open-label trial. J Clin Endocrinol Metab 2012, 97(October (10)):3495-3503.
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.OCTOBER 10 , pp. 3495-3503
    • Kroiss, M.1    Quinkler, M.2    Johanssen, S.3
  • 72
    • 84857943100 scopus 로고    scopus 로고
    • Phase II study of weekly paclitaxel and sorafenib as second/third-line therapy in patients with adrenocortical carcinoma
    • Berruti A., Sperone P., Ferrero A., et al. Phase II study of weekly paclitaxel and sorafenib as second/third-line therapy in patients with adrenocortical carcinoma. Eur J Endocrinol 2012, 166(March (3)):451-458.
    • (2012) Eur J Endocrinol , vol.166 , Issue.MARCH 3 , pp. 451-458
    • Berruti, A.1    Sperone, P.2    Ferrero, A.3
  • 73
    • 75149143015 scopus 로고    scopus 로고
    • Bevacizumab plus capecitabine as a salvage therapy in advanced adrenocortical carcinoma
    • Wortmann S., Quinkler M., Ritter C., et al. Bevacizumab plus capecitabine as a salvage therapy in advanced adrenocortical carcinoma. Eur J Endocrinol 2010, 162(February (2)):349-356.
    • (2010) Eur J Endocrinol , vol.162 , Issue.FEBRUARY 2 , pp. 349-356
    • Wortmann, S.1    Quinkler, M.2    Ritter, C.3
  • 74
    • 34249933404 scopus 로고    scopus 로고
    • Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • Moore M.J., Goldstein D., Hamm J., et al. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2007, 25(May (15)):1960-1966.
    • (2007) J Clin Oncol , vol.25 , Issue.MAY 15 , pp. 1960-1966
    • Moore, M.J.1    Goldstein, D.2    Hamm, J.3
  • 75
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small-cell lung cancer
    • Shepherd F.A., Rodrigues Pereira J., Ciuleanu T., et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005, 353(July (2)):123-132.
    • (2005) N Engl J Med , vol.353 , Issue.JULY 2 , pp. 123-132
    • Shepherd, F.A.1    Rodrigues Pereira, J.2    Ciuleanu, T.3
  • 76
    • 84908337294 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) as a potential new target in the treatment of patients with adrenocortical carcinoma: results of pre-clinical studies
    • [Abstr. 21025]
    • Fassnacht M., Hahner S., Adam P., et al. Epidermal growth factor receptor (EGFR) as a potential new target in the treatment of patients with adrenocortical carcinoma: results of pre-clinical studies. Annual meeting proceedings (post-meeting edition), 25 2007, [Abstr. 21025].
    • (2007) Annual meeting proceedings (post-meeting edition), 25
    • Fassnacht, M.1    Hahner, S.2    Adam, P.3
  • 77
    • 45149110737 scopus 로고    scopus 로고
    • Treatment of advanced adrenocortical carcinoma with erlotinib plus gemcitabine
    • Quinkler M., Hahner S., Wortmann S., et al. Treatment of advanced adrenocortical carcinoma with erlotinib plus gemcitabine. J Clin Endocrinol Metab 2008, 93(June (6)):2057-2062.
    • (2008) J Clin Endocrinol Metab , vol.93 , Issue.JUNE 6 , pp. 2057-2062
    • Quinkler, M.1    Hahner, S.2    Wortmann, S.3
  • 79
    • 0030890465 scopus 로고    scopus 로고
    • Biological characteristics of adrenocortical carcinoma: a study of p53, IGF, EGF-r, Ki-67 and PCNA in 17 adrenocortical carcinomas
    • Edgren M., Eriksson B., Wilander E., Westlin J.E., Nilsson S., Oberg K. Biological characteristics of adrenocortical carcinoma: a study of p53, IGF, EGF-r, Ki-67 and PCNA in 17 adrenocortical carcinomas. Anticancer Res 1997, 17(March-April (2B)):1303-1309.
    • (1997) Anticancer Res , vol.17 , Issue.MARCH APRIL 2B , pp. 1303-1309
    • Edgren, M.1    Eriksson, B.2    Wilander, E.3    Westlin, J.E.4    Nilsson, S.5    Oberg, K.6
  • 80
    • 84875543855 scopus 로고    scopus 로고
    • Clinical development of insulin-like growth factor receptor - 1 (IGF-1R) inhibitors: at the crossroad?
    • Gombos A., Metzger-Filho O., Dal Lago L., Awada-Hussein A. Clinical development of insulin-like growth factor receptor - 1 (IGF-1R) inhibitors: at the crossroad?. Invest New Drugs 2012, 30(December (6)):2433-2442.
    • (2012) Invest New Drugs , vol.30 , Issue.DECEMBER 6 , pp. 2433-2442
    • Gombos, A.1    Metzger-Filho, O.2    Dal Lago, L.3    Awada-Hussein, A.4
  • 81
    • 84863106031 scopus 로고    scopus 로고
    • The next generation of therapies for adrenocortical cancers
    • Kirschner L.S. The next generation of therapies for adrenocortical cancers. Trends Endocrinol Metab 2012, 23(July (7)):343-350.
    • (2012) Trends Endocrinol Metab , vol.23 , Issue.JULY 7 , pp. 343-350
    • Kirschner, L.S.1
  • 82
    • 75749102231 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma
    • Haluska P., Worden F., Olmos D., et al. Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma. Cancer Chemother Pharmacol 2010, 65(March (4)):765-773.
    • (2010) Cancer Chemother Pharmacol , vol.65 , Issue.MARCH 4 , pp. 765-773
    • Haluska, P.1    Worden, F.2    Olmos, D.3
  • 83
    • 84892502971 scopus 로고    scopus 로고
    • Phase 2 trial of cixutumumab in children, adolescents, and young adults with refractory solid tumors: a report from the Children's Oncology Group
    • [Epub 2013 Aug 17]
    • Weigel B., Malempati S., Reid J.M., et al. Phase 2 trial of cixutumumab in children, adolescents, and young adults with refractory solid tumors: a report from the Children's Oncology Group. Pediatr Blood Cancer 2014, 61(March (3)):452-456. [Epub 2013 Aug 17]. 10.1002/pbc.24605.
    • (2014) Pediatr Blood Cancer , vol.61 , Issue.MARCH 3 , pp. 452-456
    • Weigel, B.1    Malempati, S.2    Reid, J.M.3
  • 84
    • 77958073952 scopus 로고    scopus 로고
    • Phase I study of intermittent dosing of OSI-906, a dual tyrosine kinase inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR) in patients with advanced solid tumors
    • [abstr 2530]
    • Carden C.P., Kim E.S., Jones R.L., et al. Phase I study of intermittent dosing of OSI-906, a dual tyrosine kinase inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR) in patients with advanced solid tumors. J Clin Oncol 2010, 28(Suppl.):15s. [abstr 2530].
    • (2010) J Clin Oncol , vol.28 , pp. 15s
    • Carden, C.P.1    Kim, E.S.2    Jones, R.L.3
  • 85
    • 84887078420 scopus 로고    scopus 로고
    • Metabolic complications with the use of mTOR inhibitors for cancer therapy
    • [Epub 2013 May 16]
    • Sivendran S., Agarwal N., Gartrell B., et al. Metabolic complications with the use of mTOR inhibitors for cancer therapy. Cancer Treat Rev 2014, 40(February (1)):190-196. [Epub 2013 May 16]. 10.1016/j.ctrv.2013.04.005.
    • (2014) Cancer Treat Rev , vol.40 , Issue.FEBRUARY 1 , pp. 190-196
    • Sivendran, S.1    Agarwal, N.2    Gartrell, B.3
  • 86
    • 84867539766 scopus 로고    scopus 로고
    • Efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 in a preclinical model of adrenocortical carcinoma
    • Doghman M., Lalli E. Efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 in a preclinical model of adrenocortical carcinoma. Mol Cell Endocrinol 2012, 364(November (1-2)):101-104.
    • (2012) Mol Cell Endocrinol , vol.364 , Issue.1-2 NOVEMBER , pp. 101-104
    • Doghman, M.1    Lalli, E.2
  • 87
    • 84862673869 scopus 로고    scopus 로고
    • The role of mTOR inhibitors in the inhibition of growth and cortisol secretion in human adrenocortical carcinoma cells
    • De Martino M.C., van Koetsveld P.M., Feelders R.A., et al. The role of mTOR inhibitors in the inhibition of growth and cortisol secretion in human adrenocortical carcinoma cells. Endocr Relat Cancer 2012, 19(Jun (3)):351-364.
    • (2012) Endocr Relat Cancer , vol.19 , Issue.Jun 3 , pp. 351-364
    • De Martino, M.C.1    van Koetsveld, P.M.2    Feelders, R.A.3
  • 88
    • 80052831572 scopus 로고    scopus 로고
    • Phase I trial of cixutumumab combined with temsirolimus in patients with advanced cancer
    • Naing A., Kurzrock R., Burger A., et al. Phase I trial of cixutumumab combined with temsirolimus in patients with advanced cancer. Clin Cancer Res 2011, 17(September (18)):6052-6060.
    • (2011) Clin Cancer Res , vol.17 , Issue.SEPTEMBER 18 , pp. 6052-6060
    • Naing, A.1    Kurzrock, R.2    Burger, A.3
  • 90
    • 50649101532 scopus 로고    scopus 로고
    • Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex
    • Kim A.C., Reuter A.L., Zubair M., et al. Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex. Development 2008, 135(August (15)):2593-2602.
    • (2008) Development , vol.135 , Issue.AUGUST 15 , pp. 2593-2602
    • Kim, A.C.1    Reuter, A.L.2    Zubair, M.3
  • 91
    • 0038636318 scopus 로고    scopus 로고
    • Tumor formation by genetic mutations in the components of the Wnt signaling pathway
    • Kikuchi A. Tumor formation by genetic mutations in the components of the Wnt signaling pathway. Cancer Science 2003, 94(March (3)):225-229.
    • (2003) Cancer Science , vol.94 , Issue.MARCH 3 , pp. 225-229
    • Kikuchi, A.1
  • 92
    • 34548513061 scopus 로고    scopus 로고
    • The Wnt/beta-catenin signaling pathway as a target in drug discovery
    • Takahashi-Yanaga F., Sasaguri T. The Wnt/beta-catenin signaling pathway as a target in drug discovery. J Pharmacol Sci 2007, 104(August (4)):293-302.
    • (2007) J Pharmacol Sci , vol.104 , Issue.AUGUST 4 , pp. 293-302
    • Takahashi-Yanaga, F.1    Sasaguri, T.2
  • 93
    • 49249137734 scopus 로고    scopus 로고
    • The T cell factor/beta-catenin antagonist PKF115-584 inhibits proliferation of adrenocortical carcinoma cells
    • Doghman M., Cazareth J., Lalli E. The T cell factor/beta-catenin antagonist PKF115-584 inhibits proliferation of adrenocortical carcinoma cells. J Clin Endocrinol Metab 2008, 93(August (8)):3222-3225.
    • (2008) J Clin Endocrinol Metab , vol.93 , Issue.AUGUST 8 , pp. 3222-3225
    • Doghman, M.1    Cazareth, J.2    Lalli, E.3
  • 94
    • 33745067446 scopus 로고    scopus 로고
    • The role of imatinib mesylate (Glivec) for treatment of patients with malignant endocrine tumors positive for c-kit or PDGF-R
    • Gross D.J., Munter G., Bitan M., et al. The role of imatinib mesylate (Glivec) for treatment of patients with malignant endocrine tumors positive for c-kit or PDGF-R. Endocr Relat Cancer 2006, 13(June (2)):535-540.
    • (2006) Endocr Relat Cancer , vol.13 , Issue.JUNE 2 , pp. 535-540
    • Gross, D.J.1    Munter, G.2    Bitan, M.3
  • 95
    • 84908319321 scopus 로고    scopus 로고
    • Phase II study of dovitinib in first line metastatic or (nonresectable primary) adrenocortical carcinoma (ACC): SOGUG study 2011-03
    • [abstr 4587]
    • García-Donas J., Hernando Polo S., Guix M., et al. Phase II study of dovitinib in first line metastatic or (nonresectable primary) adrenocortical carcinoma (ACC): SOGUG study 2011-03. J Clin Oncol 2013, 31(Suppl.). [abstr 4587].
    • (2013) J Clin Oncol , vol.31
    • García-Donas, J.1    Hernando Polo, S.2    Guix, M.3
  • 96
    • 84880709088 scopus 로고    scopus 로고
    • A phase I dose-escalation study of TKM-080301, a RNAi therapeutic directed against polo-like kinase 1 (PLK1), in patients with advanced solid tumors: expansion cohort evaluation of biopsy samples for evidence of pharmacodynamic effects of PLK1 inhibition
    • [ASCO Annual Meeting Abstract]
    • Northfelt D.W., Hamburg S.I., Borad M.J., et al. A phase I dose-escalation study of TKM-080301, a RNAi therapeutic directed against polo-like kinase 1 (PLK1), in patients with advanced solid tumors: expansion cohort evaluation of biopsy samples for evidence of pharmacodynamic effects of PLK1 inhibition. J Clin Oncol 2013, 31(15 Suppl.). [ASCO Annual Meeting Abstract].
    • (2013) J Clin Oncol , vol.31 , Issue.15
    • Northfelt, D.W.1    Hamburg, S.I.2    Borad, M.J.3
  • 97
    • 70349673595 scopus 로고    scopus 로고
    • A phase I study of sunitinib plus bevacizumab in advanced solid tumors
    • Rini B.I., Garcia J.A., Cooney M.M., et al. A phase I study of sunitinib plus bevacizumab in advanced solid tumors. Clin Cancer Res 2009, 15(October (19)):6277-6283.
    • (2009) Clin Cancer Res , vol.15 , Issue.OCTOBER 19 , pp. 6277-6283
    • Rini, B.I.1    Garcia, J.A.2    Cooney, M.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.