TRIM59 is up-regulated in gastric tumors, promoting ubiquitination and degradation of p53

Gastroenterology

Volumn 147, Issue 5, 2014, Pages 1043-1054

  Zhou, Zhicheng ^a   Ji, Zhongzhong ^a   Wang, You ^a   Li, Jian ^b   Cao, Hui ^c   Zhu, Helen He ^a   Gao, Wei Qiang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b NANCHANG UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Oncogene; Progression; Stomach Cancer; Tumor Formation

Indexed keywords

MESSENGER RNA; PROTEIN P53; TRIPARTITE MOTIF PROTEIN 59; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; METALLOPROTEIN; TP53 PROTEIN, HUMAN; TRIM59 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER SURVIVAL; CELL DIFFERENTIATION; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CLINICAL ARTICLE; CLONOGENESIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; GASTRIC CANCER CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IN VITRO STUDY; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MICROARRAY; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STOMACH CANCER; TUMOR PROMOTION; UBIQUITINATION; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CANCER STAGING; CELL MOTION; DNA MICROARRAY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; MALE; METABOLISM; MIDDLE AGED; MORTALITY; NUDE MOUSE; PATHOLOGY; PROCEDURES; PROPORTIONAL HAZARDS MODEL; PROTEIN PROCESSING; STOMACH TUMOR; TIME; TUMOR CELL LINE; TUMOR INVASION; TUMOR VOLUME;

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HUMANS; MALE; MEMBRANE PROTEINS; METALLOPROTEINS; MICE, INBRED BALB C; MICE, NUDE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROPORTIONAL HAZARDS MODELS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; RNA, MESSENGER; STOMACH NEOPLASMS; TIME FACTORS; TRANSFECTION; TUMOR BURDEN; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINATION; UP-REGULATION;

EID: 84908302661     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2014.07.021     Document Type: Article

References (32)

1. A. Jemal, F. Bray, and M.M. Center Global cancer statistics CA Cancer J Clin 61 2011 69 90
2. Y. Lin, J. Ueda, and S. Kikuchi Comparative epidemiology of gastric cancer between Japan and China World J Gastroenterol 17 2011 4421 4428
3. B. Vogelstein, D. Lane, and A.J. Levine Surfing the p53 network Nature 408 2000 307 310
4. F. Imazeki, M. Omata, and H. Nose p53 gene mutations in gastric and esophageal cancers Gastroenterology 103 1992 892 896
5. M.F. Bellini, A.C. Cadamuro, and M. Succi Alterations of the TP53 gene in gastric and esophageal carcinogenesis J Biomed Biotechnol 2012 2012 891961
6. H.E. Gabbert, W. Muller, and A. Schneiders The relationship of p53 expression to the prognosis of 418 patients with gastric carcinoma Cancer 76 1995 720 726
7. K. Ozato, D.M. Shin, and T.H. Chang TRIM family proteins and their emerging roles in innate immunity Nat Rev Immunol 8 2008 849 860
8. G.A. Versteeg, R. Rajsbaum, and M.T. Sanchez-Aparicio The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors Immunity 38 2013 384 398
9. S. Nisole, J.P. Stoye, and A. Saib TRIM family proteins: retroviral restriction and antiviral defence Nat Rev Microbiol 3 2005 799 808
10. S. Klugbauer, and H.M. Rabes The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas Oncogene 18 1999 4388 4393
11. B. Le Douarin, C. Zechel, and J.M. Garnier The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18 EMBO J 14 1995 2020 2033
12. A.D. Goddard, J. Borrow, and P.S. Freemont Characterization of a zinc finger gene disrupted by the t(15;17) in acute promyelocytic leukemia Science 254 1991 1371 1374
13. H. de The, C. Lavau, and A. Marchio The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR Cell 66 1991 675 684
14. A. Kakizuka, W.H. Miller Jr., and K. Umesono Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML Cell 66 1991 663 674
15. S. Hatakeyama TRIM proteins and cancer Nat Rev Cancer 11 2011 792 804
16. F. Valiyeva, F. Jiang, and A. Elmaadawi Characterization of the oncogenic activity of the novel TRIM59 gene in mouse cancer models Mol Cancer Ther 10 2011 1229 1240
17. T. Matozaki, C. Sakamoto, and T. Suzuki p53 gene mutations in human gastric cancer: wild-type p53 but not mutant p53 suppresses growth of human gastric cancer cells Cancer Res 52 1992 4335 4341
18. K. Polyak, Y. Xia, and J.L. Zweier A model for p53-induced apoptosis Nature 389 1997 300 305
19. Y. Haupt, R. Maya, and A. Kazaz Mdm2 promotes the rapid degradation of p53 Nature 387 1997 296 299
20. R. Honda, H. Tanaka, and H. Yasuda Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53 FEBS Lett 420 1997 25 27
21. T. Sugiura The cellular level of TRIM31, an RBCC protein overexpressed in gastric cancer, is regulated by multiple mechanisms including the ubiquitin-proteasome system Cell Biol Int 35 2011 657 661
22. Y. Kosaka, H. Inoue, and T. Ohmachi Tripartite motif-containing 29 (TRIM29) is a novel marker for lymph node metastasis in gastric cancer Ann Surg Oncol 14 2007 2543 2549
23. T. Yokoe, Y. Toiyama, and Y. Okugawa KAP1 is associated with peritoneal carcinomatosis in gastric cancer Ann Surg Oncol 17 2010 821 828
24. T. Sugiura, and K. Miyamoto Characterization of TRIM31, upregulated in gastric adenocarcinoma, as a novel RBCC protein J Cell Biochem 105 2008 1081 1091
25. Z. Yuan, A. Villagra, and L. Peng The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions Mol Cell Biol 30 2010 3004 3015
26. Z. Yuan, L. Peng, and R. Radhakrishnan Histone deacetylase 9 (HDAC9) regulates the functions of the ATDC (TRIM29) protein J Biol Chem 285 2010 39329 39338
27. A. Ventura, D.G. Kirsch, and M.E. McLaughlin Restoration of p53 function leads to tumour regression in vivo Nature 445 2007 661 665
28. M.A. Christophorou, I. Ringshausen, and A.J. Finch The pathological response to DNA damage does not contribute to p53-mediated tumour suppression Nature 443 2006 214 217
29. W. Xue, L. Zender, and C. Miething Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas Nature 445 2007 656 660
30. Y. Wang, Y.A. Suh, and M.Y. Fuller Restoring expression of wild-type p53 suppresses tumor growth but does not cause tumor regression in mice with a p53 missense mutation J Clin Invest 121 2011 893 904
31. M. D'Errico, E. de Rinaldis, and M.F. Blasi Genome-wide expression profile of sporadic gastric cancers with microsatellite instability Eur J Cancer 45 2009 461 469
32. Q. Wang, Y.G. Wen, and D.P. Li Upregulated INHBA expression is associated with poor survival in gastric cancer Med Oncol 29 2012 77 83