Gold nanoparticle-mediated photothermal therapy: Current status and future perspective

Nanomedicine

Volumn 9, Issue 13, 2014, Pages 2003-2022

  Hwang, Sekyu ^a   Nam, Jutaek ^a   Jung, Sungwook ^a   Song, Jaejung ^a   Doh, Hyunmi ^a   Kim, Sungjee ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

drug delivery; gold nanoparticle; medical imaging; nanomedicine; near infrared; photothermal therapy; theragnostics

Indexed keywords

DOXORUBICIN; FLUOROCARBON; GOLD NANOPARTICLE; NANOCAGE; NANOCARRIER; NANOPARTICLE; NANOPOPCORN; NANOROD; NANOSHELL; NANOSPHERE; NANOSTAR; PHOTOSENSITIZING AGENT; TRASTUZUMAB; UNCLASSIFIED DRUG; GOLD; METAL NANOPARTICLE;

ANISOTROPY; CANCER CELL DESTRUCTION; CANCER THERAPY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG STABILITY; HEATING; HUMAN; HYPERTHERMIC THERAPY; LIGHT; LIGHT ABSORPTION; NANOENGINEERING; NEAR INFRARED LIGHT; NONHUMAN; PARTICLE SIZE; PHOTON; PHOTOTHERAPY; PHOTOTHERMAL THERAPY; REVIEW; SURFACE PLASMON RESONANCE; TISSUE SPECIFICITY; NEOPLASMS; PATHOLOGY; TISSUE DISTRIBUTION;

GOLD; HUMANS; METAL NANOPARTICLES; NANOSHELLS; NEOPLASMS; PHOTOSENSITIZING AGENTS; PHOTOTHERAPY; SURFACE PLASMON RESONANCE; TISSUE DISTRIBUTION;

EID: 84908284943     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.14.147     Document Type: Review

References (89)

1. Srivatsan A, Jenkins SV, Jeon M et al. Gold nanocage-photosensitizer conjugates for dual-modal image-guided enhanced photodynamic therapy. Theranostics 4(2), 163-174 (2014).
2. Kim C, Favazza C, Wang LV. In vivo photoacoustic tomography of chemicals: High-resolution functional and molecular optical imaging at new depths. Chem. Rev. 110, 2756-2782 (2010).
3. Nikoobakht B, El-Sayed MA. Preparation and growth mechanism of gold nanorods (NRs) using seed-mediated growth method. Chem. Mater. 15(10), 1957-1962 (2003).
4. Chen J, Yang M, Zhang Q et al. Gold nanocages: A novel class of multifunctional nanomaterials for theranostic applications. Adv. Funct. Mater. 20, 3684-3694 (2010).
5. Svaasand L, Gomer C, Morinelli E. On the physical rationale of laser induced hyperthermia. Laser Med. Sci. 5(2), 121-128 (1990).
6. Song CW. Effect of local hyperthermia on blood flow and microenvironment: A review. Cancer Res. 44(10 Suppl.), 4721s-4730s (1984).
7. Satishchandra P, Shivaramakrishana A, Kaliaperumal VG, Schoenberg BS. Hot-water epilepsy: A variant of reflex epilepsy in Southern India. Epilepsia 29(1), 52-56 (1988).
8. Ullal GR, Satishchandra P, Shankar SK. Hyperthermic seizures: An animal model for hot-water epilepsy. Seizure 5(3), 221-228 (1996).
9. Seegenschmiedt MH, Brady LW, Sauer R. Interstitial thermoradiotherapy: Review on technical and clinical aspects. Am. J. Clin. Oncol. 13(4), 352-363 (1990).
10. Sato M, Watanabe Y, Ueda S et al. Microwave coagulation therapy for hepatocellular carcinoma. Gastroenterology 110(5), 1507-1514 (1996).
11. Kremkau FW. Cancer therapy with ultrasound: A historical review. J. Clin. Ultrasound 7(4), 287-300 (1979).
12. Wu F, Chen W-Z, Bai J et al. Pathological changes in human malignant carcinoma treated with high-intensity focused ultrasound. Ultrasound Med. Biol. 27(8), 1099-1106 (2001).
13. Goldberg SN. Radiofrequency tumor ablation: Principles and techniques. Eur. J. Ultrasound 13(2), 129-147 (2001).
14. Gazelle GS, Goldberg SN, Solbiati L, Livraghi T. Tumor ablation with radio-frequency energy. Radiology 217(3), 633-646 (2000).
15. Asimov MM, Asimov RM, Rubinov AN. Efficiency of laser action on hemoglobin and oxyhemoglobin in skin blood vessels. Proc. SPIE 3254, 407-412 (1998).
16. Jin CS, Lovell JF, Chen J, Zheng G. Ablation of hypoxic tumors with dose-equivalent photothermal, but not photodynamic, therapy using a nanostructured porphyrin assembly. ACS Nano 7(3), 2541-2550 (2013).
17. Lovell JF, Jin CS, Huynh E et al. Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents. Nat. Mater. 10(4), 324-332 (2011).
18. Lim CK, Shin J, Lee YD et al. Phthalocyanine-Aggregated polymeric nanoparticles as tumor-homing near-infrared absorbers for photothermal therapy of cancer. Theranostics 2(9), 871-879 (2012).
19. Chen WR, Adams RL, Heaton S, Dickey DT, Bartels KE, Nordquist RE. Chromophore-enhanced laser-Tumor tissue photothermal interaction using an 808-nm diode laser. Cancer Lett. 88(1), 15-19 (1995).
20. Link S, El-Sayed MA. Spectral properties and relaxation dynamics of surface plasmon electronic oscillations in gold and silver nanodots and nanorods. J. Phys. Chem. B 103(40), 8410-8426 (1999).
21. Richardson HH, Carlson MT, Tandler PJ, Hernandez P, Govorov AO Experimental and Theoretical Studies of Light-To-heat Conversion and Collective Heating Effects in Metal Nanoparticle Solutions. Nano Lett. 9(3), 1139-1146 (2009).
22. Sonnichsen C, Reinhard BM, Liphardt J, Alivisatos AP. A molecular ruler based on plasmon coupling of single gold and silver nanoparticles. Nat. Biotechnol. 23(6), 741-745 (2005).
23. Weissleder R. A clearer vision for in vivo imaging. Nat. Biotechnol. 19(4), 316-317 (2001).
24. Kelly KL, Coronado E, Zhao LL, Schatz GC. The Optical properties of metal nanoparticles: The influence of size, shape, and dielectric environment. J. Phys. Chem. B 107(3), 668-677 (2002).
25. Oldenburg SJ, Averitt RD, Westcott SL, Halas NJ. Nanoengineering of optical resonances. Chem. Phys. Lett. 288(2-4), 243-247 (1998).
26. Pissuwan D, Valenzuela SM, Cortie MB. Therapeutic possibilities of plasmonically heated gold nanoparticles. Trends Biotechnol. 24(2), 62-67 (2006).
27. Hirsch LR, Stafford RJ, Bankson JA et al. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc. Natl Acad. Sci. USA 100(23), 13549-13554 (2003).
28. Loo C, Lowery A, Halas N, West J, Drezek R Immunotargeted Nanoshells for Integrated Cancer Imaging and Therapy. Nano Lett. 5(4), 709-711 (2005).
29. Fekrazad R, Hakimiha N, Farokhi E et al. Treatment of oral squamous cell carcinoma using anti-HER2 immunonanoshells. Int. J. Nanomed. 6, 2749-2755 (2011).
30. Liu SY, Liang ZS, Gao F, Luo SF, Lu GQ. In vitro photothermal study of gold nanoshells functionalized with small targeting peptides to liver cancer cells. J. Mater. Sci. Mater. Med. 21(2), 665-674 (2010).
31. Wu CY, Yu C, Chu MQ. A gold nanoshell with a silica inner shell synthesized using liposome templates for doxorubicin loading and near-infrared photothermal therapy. Int. J. Nanomed. 6, 807-813 (2011).
32. You J, Zhang R, Xiong CY et al. Effective photothermal chemotherapy using doxorubicin-loaded gold nanospheres that target EphB4 receptors in tumors. Cancer Res. 72(18), 4777-4786 (2012).
33. Melancon MP, Lu W, Zhong M et al. Targeted multifunctional gold-based nanoshells for magnetic resonance-guided laser ablation of head and neck cancer. Biomaterials 32(30), 7600-7608 (2011).
34. Ma Y, Liang X, Tong S, Bao G, Ren Q, Dai Z. Gold nanoshell nanomicelles for potential magnetic resonance imaging, light-Triggered drug release, and photothermal therapy. Adv. Func. Mater. 23(7), 815-822 (2013).
35. Ke HT, Wang JR, Tong S et al. Gold nanoshelled liquid perfluorocarbon magnetic nanocapsules: A nanotheranostic platform for bimodal ultrasound/magnetic resonance imaging guided photothermal tumor ablation. Theranostics 4(1), 12-23 (2014). Pilot study of AuroLase™ therapy in refractory and/or recurrent tumors of the head and neck. http://clinicaltrials.gov/ct2/show/nct00848042
36. Link S, Mohamed MB, El-Sayed MA. Simulation of the optical absorption spectra of gold nanorods as a function of their aspect ratio and the effect of the medium dielectric constant. J. Phys. Chem. B 103(16), 3073-3077 (1999).
37. Van Der Zande BMI, Bohmer MR, Fokkink LGJ, Schonenberger C. Colloidal dispersions of gold rods: Synthesis and optical properties. Langmuir 16(2), 451-458 (2000).
38. Huang XH, El-Sayed IH, Qian W, El-Sayed MA. Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods. J. Am. Chem. Soc. 128(6), 2115-2120 (2006).
39. Dickerson EB, Dreaden EC, Huang XH et al. Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of squamous cell carcinoma in mice. Cancer Lett. 269(1), 57-66 (2008).
40. Pissuwan D, Valenzuela SM, Killingsworth MC, Xu XD, Cortie MB. Targeted destruction of murine macrophage cells with bioconjugated gold nanorods. J. Nanopart. Res. 9(6), 1109-1124 (2007).
41. Pissuwan D, Valenzuela SM, Miller CM, Cortie MB. A golden bullet?. Selective targeting of Toxoplasma gondii tachyzoites using antibody-functionalized gold nanorods. Nano Lett. 7(12), 3808-3812 (2007).
42. Choi WI, Kim JY, Kang C, Byeon CC, Kim YH, Tee G. Tumor regression in vivo by photothermal therapy based on gold-nanorod-loaded, functional nanocarriers. ACS Nano 5(3), 1995-2003 (2011).
43. Kim ST, Saha K, Kim C, Rotello VM. The Role of surface functionality in determining nanoparticle cytotoxicity. Acc. Chem. Res. 46(3), 681-691 (2013).
44. Akiyama Y, Mori T, Katayama Y, Niidome T. The effects of PEG grafting level and injection dose on gold nanorod biodistribution in the tumor-bearing mice. J. Control. Release 139(1), 81-84 (2009).
45. Chen Y-S, Frey W, Kim S et al. Enhanced thermal stability of silica-coated gold nanorods for photoacoustic imaging and image-guided therapy. Opt. Express 18(9), 8867-8878 (2010).
46. Huang P, Bao L, Zhang C et al. Folic acid-conjugated silica-modified gold nanorods for x-ray/CT imaging-guided dual-mode radiation and photo-Thermal therapy. Biomaterials 32(36), 9796-9809 (2011).
47. Qiu Y, Liu Y, Wang L et al. Surface chemistry and aspect ratio mediated cellular uptake of Au nanorods. Biomaterials 31(30), 7606-7619 (2010).
48. Kirui DK, Krishnan S, Strickland AD, Batt CA. PAA-derived gold nanorods for cellular targeting and photothermal therapy. Macromol. Biosci. 11(6), 779-788 (2011).
49. Xu C, Yang D, Mei L, Li Q, Zhu H, Wang T. Targeting chemophotothermal therapy of hepatoma by gold nanorods/graphene oxide core/shell nanocomposites. ACS Appl. Mater. Interfaces 5(24), 12911-12920 (2013).
50. Von Maltzahn G, Park JH, Agrawal A et al. Computationally guided photothermal tumor therapy using long-circulating gold nanorod antennas. Cancer Res. 69(9), 3892-3900 (2009).
51. Yeager D, Chen YS, Litovsky S, Emelianov S. Intravascular photoacoustics for image-guidance and temperature monitoring during plasmonic photothermal therapy of atherosclerotic plaques: A feasibility study. Theranostics 4(1), 36-46 (2014).
52. Black KCL, Yi J, Rivera JG, Zelasko-Leon DC, Messersmith PB. Polydopamine-enabled surface functionalization of gold nanorods for cancer cell-Targeted imaging and photothermal therapy. Nanomedicine 8(1), 17-28 (2012).
53. Sun Y, Mayers BT, Xia Y Template-engaged replacement reaction: A one-step approach to the large-scale synthesis of metal nanostructures with hollow interiors. Nano Lett. 2(5), 481-485 (2002).
54. Sun Y, Xia Y. Mechanistic Study on the replacement reaction between silver nanostructures and chloroauric acid in aqueous medium. J. Am. Chem. Soc. 126(12), 3892-3901 (2004).
55. Chen J, Wang D, Xi J et al Immuno Gold Nanocages with Tailored Optical Properties for Targeted Photothermal Destruction of Cancer Cells. Nano Lett. 7(5), 1318-1322 (2007).
56. Au L, Zheng D, Zhou F, Li Z-Y, Li X, Xia Y. A Quantitative study on the photothermal effect of immuno gold nanocages targeted to breast cancer cells. ACS Nano 2(8), 1645-1652 (2008).
57. Chen J, Glaus C, Laforest R et al. Gold nanocages as photothermal transducers for cancer treatment. Small 6(7), 811-817 (2010).
58. Khlebtsov B, Panfilova E, Khanadeev V et al. Nanocomposites containing silica-coated gold-silver nanocages and Yb-2,4-dimethoxyhematoporphyrin: Multifunctional capability of IR-luminescence detection, photosensitization, and photothermolysis. ACS Nano 5(9), 7077-7089 (2011).
59. Gao L, Fei J, Zhao J, Li H, Cui Y, Li J. Hypocrellin-loaded gold nanocages with high two-photon efficiency for photothermal/photodynamic cancer therapy in vitro. ACS Nano 6(9), 8030-8040 (2012).
60. Khan SA, Kanchanapally R, Fan Z et al. A gold nanocage-CNT hybrid for targeted imaging and photothermal destruction of cancer cells. Chem. Commun. 48(53), 6711-6713 (2012).
61. Shi P, Qu K, Wang J, Li M, Ren J, Qu X. pH-responsive NIR enhanced drug release from gold nanocages possesses high potency against cancer cells. Chem. Commun. 48(61), 7640-7642 (2012).
62. Yang J, Shen D, Zhou L et al. Spatially confined fabrication of core-shell gold nanocages@mesoporous silica for near-infrared controlled photothermal drug release. Chem. Mater. 25(15), 3030-3037 (2013).
63. Hao F, Nehl CL, Hafner JH, Nordlander P Plasmon Resonances of A Gold Nanostar. Nano Lett. 7(3), 729-732 (2007).
64. Yuan H, Khoury CG, Hwang H, Wilson CM, Grant GA, Vo-Dinh T. Gold nanostars: Surfactant-free synthesis, 3D modelling, and two-photon photoluminescence imaging. Nanotechnology 23(7), 075102 (2012).
65. Barbosa S, Agrawal A, Rodríguez-Lorenzo L et al. Tuning size and sensing properties in colloidal gold nanostars. Langmuir 26(18), 14943-14950 (2010).
66. Dondapati SK, Sau TK, Hrelescu C, Klar TA, Stefani FD, Feldmann J. Label-free biosensing based on single gold nanostars as plasmonic transducers. ACS Nano 4(11), 6318-6322 (2010).
67. Van De Broek B, Devoogdt N, D'Hollander A et al. Specific cell targeting with nanobody conjugated branched gold nanoparticles for photothermal therapy. ACS Nano 5(6), 4319-4328 (2011).
68. Yuan H, Khoury CG, Wilson CM, Grant GA, Bennett AJ, Vo-Dinh T. In vivo particle tracking and photothermal ablation using plasmon-resonant gold nanostars. Nanomedicine 8(8), 1355-1363 (2012).
69. Yuan H, Fales AM, Vo-Dinh T. TAT peptide-functionalized gold nanostars: Enhanced intracellular delivery and efficient NIR photothermal therapy using ultralow irradiance. J. Am. Chem. Soc. 134(28), 11358-11361 (2012).
70. Xie J, Lee JY, Wang DIC. Seedless, surfactantless, high-yield synthesis of branched gold nanocrystals in HEPES buffer solution. Chem. Mater. 19(11), 2823-2830 (2007).
71. Chen HY, Zhang X, Dai SH et al. Multifunctional gold nanostar conjugates for tumor imaging and combined photothermal and chemo-Therapy. Theranostics 3(9), 633-649 (2013).
72. Lu W, Singh AK, Khan SA, Senapati D, Yu H, Ray PC. Gold nano-popcorn-based targeted diagnosis, nanotherapy treatment, and in situ monitoring of photothermal therapy response of prostate cancer cells using surface-enhanced Raman spectroscopy. J. Am. Chem. Soc. 132(51), 18103-18114 (2010).
73. Beqa L, Fan Z, Singh AK, Senapati D, Ray PC. Gold nano-popcorn attached SWCNT hybrid nanomaterial for targeted diagnosis and photothermal therapy of human breast cancer cells. ACS Appl. Mater. Interfaces 3(9), 3316-3324 (2011).
74. Chithrani BD, Ghazani AA, Chan WCW. Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett. 6(4), 662-668 (2006).
75. Chithrani BD, Chan WCW. Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes. Nano Lett. 7(6), 1542-1550 (2007).
76. Choi HS, Liu W, Misra P et al. Renal clearance of quantum dots. Nat. Biotechnol. 25(10), 1165-1170 (2007).
77. Huang X, Qian W, El-Sayed IH, El-Sayed MA. The potential use of the enhanced nonlinear properties of gold nanospheres in photothermal cancer therapy. Laser Surg. Med. 39(9), 747-753 (2007).
78. Nam J, Won N, Jin H, Chung H, Kim S. pH-induced aggregation of gold nanoparticles for photothermal cancer therapy. J. Am. Chem. Soc. 131(38), 13639-13645 (2009).
79. Nam J, La W-G, Hwang S et al. pH-responsive assembly of gold nanoparticles and 'spatiotemporally concerted' drug release for synergistic cancer therapy. ACS Nano 7(4), 3388-3402 (2013).
80. Jung S, Nam J, Hwang S et al. Theragnostic pH-sensitive gold nanoparticles for the selective surface enhanced Raman scattering and photothermal cancer therapy. Anal. Chem. 85(16), 7674-7681 (2013).
81. Xiao P, Li Q, Joo Y et al. Detection of pH-induced aggregation of 'smart' gold nanoparticles with photothermal optical coherence tomography. Opt. Lett. 38(21), 4429-4432 (2013).
82. Nam J, Ha YS, Hwang S et al. pH-responsive gold nanoparticles-in-liposome hybrid nanostructures for enhanced systemic tumor delivery. Nanoscale 5(21), 10175-10178 (2013).
83. Hwang S, Nam J, Song J et al. A sub 6 nanometer plasmonic gold nanoparticle for pH-responsive near-infrared photothermal cancer therapy. New J. Chem. 38(3), 918-922 (2014).
84. He J, Huang X, Li Y-C et al. Self-Assembly of amphiphilic plasmonic micelle-like nanoparticles in selective solvents. J. Am. Chem. Soc. 135(21), 7974-7984 (2013).
85. Lin J, Wang S, Huang P et al. Photosensitizer-loaded gold vesicles with strong plasmonic coupling effect for imaging-guided photothermal/photodynamic therapy. ACS Nano 7(6), 5320-5329 (2013).
86. Huang P, Lin J, Li W et al. Biodegradable gold nanovesicles with an ultrastrong plasmonic coupling effect for photoacoustic imaging and photothermal therapy. Angew. Chem. Int. Ed. 52(52), 13958-13964 (2013).
87. Nam J, Nam H, Jung S et al. Unique photothermal response and sustained photothermal effect of pH-responsive gold-nanoparticle aggregates. Chem. Phys. Chem 13(18), 4105-4109 (2012).
88. Stern ST, Hall JB, Yu LL et al. Translational considerations for cancer nanomedicine. J. Control. Release 146(2), 164-174 (2010).
89. Libutti SK, Paciotti GF, Myer L et al. Results of a completed Phase I clinical trial of CYT-6091: A pegylated colloidal gold-TNF nanomedicine. J. Clin. Oncol. 27(15 Suppl.), 3586 (2009).