Evaluation of skeletal tissue repair, Part 2: Enhancement of skeletal tissue repair through dual-growth-factor-releasing hydrogels within an ex vivo chick femur defect model

Acta Biomaterialia

Volumn 10, Issue 10, 2014, Pages 4197-4205

  Smith, E L ^a   Kanczler, J M ^a   Gothard, D ^a   Roberts, C A ^a   Wells, J A ^a   White, L J ^b   Qutachi, O ^b   Sawkins, M J ^b   Peto, H ^b   Rashidi, H ^b   Rojo, L ^c,d   Stevens, M M ^c   El Haj, A J ^e   Rose, F R A J ^b   Shakesheff, K M ^b   Oreffo, R O C ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d CSIC   (Spain)

^e KEELE UNIVERSITY   (United Kingdom)

Author keywords

Bone repair; Dual growth factor delivery; ECM hydrogel scaffolds; Embryonic femur; Ex vivo model

Indexed keywords

ALGINATE; BONE; CELL ENGINEERING; COLLAGEN; CYTOLOGY; DEFECTS; ENDOTHELIAL CELLS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; REPAIR; SCAFFOLDS (BIOLOGY); STEM CELLS; TISSUE REGENERATION;

BONE REPAIR; DUAL GROWTH FACTOR DELIVERY; EMBRYONIC FEMUR; EMBRYONICS; EX VIVO MODEL; EX-VIVO; EXTRACELLULAR MATRICES; EXTRACELLULAR MATRIX HYDROGEL SCAFFOLD; GROWTH FACTOR DELIVERY; HYDROGEL SCAFFOLDS; VIVO MODELS;

HYDROGELS;

ALGINIC ACID; BONE MORPHOGENETIC PROTEIN 2; COPOLYMER; POLYGLYCOLIC ACID; POLYLACTIC ACID; TRANSFORMING GROWTH FACTOR BETA3; VASCULOTROPIN; GLUCURONIC ACID; HEXURONIC ACID; HYDROGEL; LACTIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; SIGNAL PEPTIDE;

ANIMAL TISSUE; ARTICLE; BONE MARROW STROMA CELL; BONE REMODELING; CELL MIGRATION; CHICK; CONTROLLED STUDY; EMBRYO; EX VIVO STUDY; EXTRACELLULAR MATRIX; FEMUR; HYDROGEL; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; SKELETAL MUSCLE; TISSUE REPAIR; ADULT; ANIMAL; BIOLOGICAL MODEL; BONE MARROW CELL; BONE REGENERATION; BOVINE; CHEMISTRY; CHICK EMBRYO; CHICKEN; CYTOLOGY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; HUMAN; INJURIES; METABOLISM; PATHOLOGY; PHARMACOLOGY; SKELETAL MUSCLE SATELLITE CELL; STROMA CELL;

ADULT; ALGINATES; ANIMALS; BONE MARROW CELLS; BONE REGENERATION; CATTLE; CHICK EMBRYO; CHICKENS; DRUG DELIVERY SYSTEMS; EXTRACELLULAR MATRIX; FEMUR; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; HYDROGELS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LACTIC ACID; MODELS, BIOLOGICAL; POLYGLYCOLIC ACID; SATELLITE CELLS, SKELETAL MUSCLE; STROMAL CELLS;

EID: 84908254762     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2014.05.025     Document Type: Article

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