The high water solubility of inclusion complex of taxifolin-γ-CD prepared and characterized by the emulsion solvent evaporation and the freeze drying combination method

International Journal of Pharmaceutics

Volumn 477, Issue 1-2, 2014, Pages 148-158

  Zu, Yuangang ^a   Wu, Weiwei ^a   Zhao, Xiuhua ^a   Li, Yong ^a   Zhong, Chen ^a   Zhang, Yin ^a  

^a NORTHEAST FORESTRY UNIVERSITY   (China)

Author keywords

Bioavailability; Emulsion solvent evaporation method; Freeze drying method; Inclusion complex; Solubility; Taxifolin

Indexed keywords

ACETIC ACID ETHYL ESTER; GAMMA CYCLODEXTRIN; SOLVENT; TAXIFOLIN; ANTIOXIDANT; EMULSION; GAMMA CYCLODEXTRIN DERIVATIVE; GAMMA-CYCLODEXTRIN; QUERCETIN; WATER;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CHEMICAL STRUCTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG SOLUBILITY; EMULSION; EVAPORATION; FEMALE; FREEZE DRYING; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMOGENATE; HYDROGEN BOND; INFRARED SPECTROSCOPY; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PROCESS OPTIMIZATION; RAT; SCANNING ELECTRON MICROSCOPY; THERMAL ANALYSIS; THERMOGRAVIMETRY; X RAY DIFFRACTION; ANALOGS AND DERIVATIVES; ANIMAL; BIOAVAILABILITY; CHEMISTRY; MEDICINAL CHEMISTRY; PROCEDURES; SOLUBILITY; SPRAGUE DAWLEY RAT; TEMPERATURE;

ANIMALS; ANTIOXIDANTS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; DRUG COMPOUNDING; EMULSIONS; FEMALE; FREEZE DRYING; GAMMA-CYCLODEXTRINS; PARTICLE SIZE; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SOLVENTS; TEMPERATURE; WATER;

EID: 84908248907     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.10.027     Document Type: Article

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