Noninvasive detection of sleep/wake changes and cataplexy-like behaviors in orexin/ataxin-3 transgenic narcoleptic mice across the disease onset

Experimental Neurology

Volumn 261, Issue , 2014, Pages 744-751

  Sato, Masatoshi ^a,b   Sagawa, Yohei ^a,b   Hirai, Nobuhide ^a   Sato, Shinichi ^a,b   Okuro, Masashi ^a,c   Kumar, Samika ^a   Kanbayashi, Takashi ^b   Shimizu, Tetsuo ^b   Sakai, Noriaki ^a   Nishino, Seiji ^a  

^a STANFORD UNIVERSITY   (United States)

^b AKITA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

Cataplexy; Disease onset; Hypocretin orexin; Mice; Narcolepsy; Piezoelectric system; REM sleep

Indexed keywords

ATAXIN 3; OREXIN; MJD PROTEIN, MOUSE; NEUROPEPTIDE; NUCLEAR PROTEIN; OREXINS; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR;

AGE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY POSTURE; CATAPLEXY; CONTROLLED STUDY; DISEASE COURSE; HEART BEAT; IMMOBILITY; MONITORING; MOUSE; MOUSE MODEL; NARCOLEPSY; NEWBORN; NON INVASIVE PROCEDURE; NONHUMAN; PIEZOELECTRIC TRANSDUCER; PIEZOELECTRICITY; REM SLEEP; SLEEP QUALITY; SLEEP WAKING CYCLE; TRANSDUCER; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; C57BL MOUSE; COMPLICATION; DISEASE MODEL; ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; GENETICS; PHYSIOLOGY; SLEEP; SLEEP DISORDERS; WAKEFULNESS;

ANIMALS; ANIMALS, NEWBORN; CATAPLEXY; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NARCOLEPSY; NEUROPEPTIDES; NUCLEAR PROTEINS; SLEEP; SLEEP DISORDERS; TRANSCRIPTION FACTORS; TRANSDUCERS; WAKEFULNESS;

EID: 84908246547     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2014.08.004     Document Type: Article

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