The electrode-tissue interface: The revolutionary role of steroid-elution

PACE - Pacing and Clinical Electrophysiology

Volumn 37, Issue 9, 2014, Pages 1232-1249

  Mond, Harry G ^a   Helland, John R ^b   Stokes, Kenneth ^c   Bornzin, Gene A ^b   McVenes, Rick ^d  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ST JUDE MEDICAL   (United States)

^c CRDM Research and Technology Division ^*  (United States)

^d MEDTRONIC INC   (United States)

Author keywords

biomedical engineering; pacing

Indexed keywords

ALLOY; ANTICOAGULANT AGENT; ANTIINFLAMMATORY AGENT; BECLOMETASONE DIPROPIONATE; DEXAMETHASONE ACETATE; DEXAMETHASONE SODIUM PHOSPHATE; HYDROXYPROLINE; IRIDIUM; PLATINUM; PREDNISOLONE; SILASTIC; STEROID; TITANIUM; TUNICAMYCIN; CORTICOSTEROID;

ACTION POTENTIAL; BIOCOMPATIBILITY; BIOPHYSICS; CONDUCTOR; ELECTRIC CURRENT; ELECTRIC FIELD; ELECTRIC POTENTIAL; ELECTRIC RESISTANCE; ELECTROPHYSIOLOGY; ELUTION; ENDOCARDIUM; EQUIPMENT DESIGN; HEART DEPOLARIZATION; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART PACING; HEART STIMULATION; HUMAN; IMPEDANCE; LEAD FRACTURE; OSMOTIC MINIPUMP; PACEMAKER ELECTRODE; PLATINUM IRIDIUM WIRE; POLARIZATION; POROSITY; PULSE GENERATOR; REVIEW; SURFACE PROPERTY; THICKNESS; ARTIFICIAL HEART PACEMAKER; CYTOLOGY; ELECTRODE IMPLANT; IMPLANTABLE CARDIOVERTER DEFIBRILLATOR; POWER SUPPLY;

ADRENAL CORTEX HORMONES; DEFIBRILLATORS, IMPLANTABLE; ELECTRIC POWER SUPPLIES; ELECTRODES, IMPLANTED; ENDOCARDIUM; EQUIPMENT DESIGN; HUMANS; MYOCARDIUM; PACEMAKER, ARTIFICIAL; SURFACE PROPERTIES;

EID: 84908224205     PISSN: 01478389     EISSN: 15408159     Source Type: Journal    
DOI: 10.1111/pace.12461     Document Type: Review

References (95)

1. Robinson TF, Cohen-Gould L, Factor SM,. Skeletal framework of mammalian heart muscle: Arrangement of inter- and pericellular connective tissue structures. Lab Invest 1983; 29: 482-498.
2. Stokes KB, Taepke, R, Gates J,. All impedances are not created equal. Expediency vs efficiency. Medtronic Sci Technol 1994; 3: 2-12.
3. Barold SS, Stokes K, Byrd CL, McVenes R,. Energy parameters in cardiac pacing should be abandoned. Pacing Clin Electrophysiol 1997; 20: 112-121.
4. Irnich W,. Engineering aspects of pacemaker electrodes. In:, Schaldach M, Furman S, (eds.): Advances in Pacemaker Technology. Berlin, Springer-Verlag, 1974, pp. 241-272.
5. Fischler H,. Polarization properties of small-surface-area pacemaker electrodes: Implications on reliability of sensing and pacing. Pacing Clin Electrophysiol 1979; 2: 403-416.
6. Wiggers CJ, Wegria R,. Ventricular fibrillation due to single, localized induction and condenser shocks applied during the vulnerable phase of ventricular systole. Am J Physiol 1940; 128: 500-505.
7. Mond H,. The Cardiac Pacemaker. Function and Malfunction. New York, Grune and Stratton 1973, pp. 60-66.
8. Schuchert A, Kuck KH,. Influence of internal current and pacing current on pacemaker longevity. Pacing Clin Electrophysiol 1994; 17: 13-16.
9. Mond H, Sloman G,. The small tined pacemaker lead. Absence of dislodgement. Pacing Clin Electrophysiol 1980; 3: 171-177.
10. Mond H, Holley L, Hirshorn M,. The high impedance dish electrode: Clinical experience with a new tined lead. Pacing Clin Electrophysiol 1982; 5: 529-534.
11. Hirshorn M, Holley LK, Mond H, Gale A, Stewart S,. Effect of pore size on threshold and impedance of pacemaker electrodes. In:, Steinbach K, Glogar D, Lsazkovics A, et al. (eds.): Proceedings of the VII World Symposium on Cardiac Pacing. Vienna, Austria, Steinkopff, Verlag and Darmstadt, 1983, pp. 383-385.
12. Charles R, Mond H, Wilson A, Markin C, Vella S, Cowling R, McMichael A, et al. A multi-center study of the laserdish electrode. In:, Belhassen B, Feldman S, Copperman Y, (eds.): Proceedings of the VIIIth World Symposium on Cardiac Pacing and Electrophysiology, Israel. Jerusalem, Keterpress Enterprises Jerusalem, 1987, pp. 9-13.
13. Mond HG,. Development of low stimulation threshold, low-polarization electrodes. In:, Barold SS, Mugica J, (eds.): New Perspectives in Cardiac Pacing, Vol. 2. Mount Kisco, New York, Futura Publishing Company, Inc., 1991, 133-162.
14. Heinemann F, Davis M, Helland J,. Clinical performance of a pacing lead with a platinized target-tip electrode (abstract). Pacing Clin Electrophysiol 1984; 7: 471.
15. Irnich W,. Engineering concepts of pacemaker leads. In:, Antonioli GE, Aubert AE, Ector H, (eds.): Proceedings of the 2nd European Conference on Pacemaker Leads. Ferrara, Italy, Elsevier, 1991, pp. 3-20.
16. Irnich W,. Considerations in electrode design for permanent pacing. In:, Thalen, HJTh, (ed.): Cardiac Pacing. Proceedings of the 4th International Symposium on Cardiac Pacing. Assen, The Netherlands, Van Gorcum, 1973, pp. 268-274.
17. Stokes K, Bird T, Gunderson B,. The mythology of threshold variations as a function of electrode surface area. Pacing Clin Electrophysiol 1991; 14: 1748-1751.
18. Parsonnet V, Zucker R, Gilbert P,. Clinical use of a new transvenous electrode. In: Furman S (ed): Advances in Cardiac Pacemakers. Annals N Y Acad Sci 1969; 167:756-760.
19. Timmis GC, Helland J, Westveer DC,. The evolution of low threshold leads. Clin Prog Pacing Electrophysiol 1983; 1: 313-333.
20. Amundson DC, McArthur W, Mosharrafa M,. The porous endocardial electrode. Pacing Clin Electrophysiol 1979; 2: 40-50.
21. MacCarter DJ, Lundberg KM, Corstjens JPM,. Porous electrodes. Concept, technology and results. Pacing Clin Electrophysiol 1983; 6: 427-435.
22. Wilson GJ, MacGregor DC, Bobby JD, Lixfeld W, Pilliar RM, Miller SL, Silver MD,. Tissue response to porous-surfaced electrodes: Basis for a new atrial lead design. In:, Meere C, (ed.): Proceedings of the VIth World Symposium on Cardiac Pacing. Montreal, Canada, Laplante and Langevin, 1979, Chapter 29-12.
23. Bobyn GJ, Wilson TR, Mycyk P, Klement GA, Tait RM, Pilliar DC, MacGregor DC,. Comparison of porous-surfaced with a totally porous ventricular endocardial pacing electrode. Pacing Clin Electrophysiol 1981; 4: 405-416.
24. Chitre Y, Helland J, Doan P, Platt B, O'Brien R, Gelb A,. Comparison of electrode efficacy for various electrode surface coatings (abstract). Pacing Clin Electrophysiol 1990; 23: 723.
25. Djordjevic M, Stojanov P, Velimirovic D, Kocovic D,. Target lead. Low threshold electrode. Pacing Clin Electrophysiol 1986; 9: 1206-1210.
26. Elmqvist H, Schueller H, Richter G,. The carbon tip electrode. Pacing Clin Electrophysiol 1983; 6: 436-439.
27. Gargeroglio B, Inguaggiato B, Chinaglia B, Cerise O,. Initial results with an activated carbon tip electrode. Pacing Clin Electrophysiol 1983; 6: 440-447.
28. nd European Conference on Pacemaker Leads. Ferrara, Italy, Elsevier, 1991, pp. 441-450.
29. Moracchini PV, Cappelletti F, Melandri PF, Barberries MA, Maiolino P, Audoglio R,. Titanium oxide tip electrode. A solution to minimize polarization and threshold increase (abstract). Pacing Clin Electrophysiol 1985; 8: A-85.
30. Mund K,. Bipolar electrode systems consisting of titanium covered with a porous titanium nitride layer. In:, Antonioli G, Aubert A, Ector H, (eds.): Proceedings of the 2nd European Conference on Pacemaker Leads. Ferrara, Italy, Elsevier, 1991, pp. 511-517.
31. Tang C, Yeung-Lai-Wah JA, Qi A, Mills P, Clark J, Tyers F,. Initial experience with a co-radial bipolar pacing lead. Pacing Clin Electrophysiol 1997; 20: 1800-1807.
32. Del Bufalo AGA, Schlaepfer J, Fromer M, Kappenberger L,. Acute and long-term ventricular stimulation thresholds with a new, Iridium oxide-coated electrode. Pacing Clin Electrophysiol 1993; 16: 1240-1244.
33. Meyle J, Gulting K, Wolburg H, Von Recum AF,. Fibroblast anchorage to micro-textured surfaces. J Biomed Mater Res 1993; 27: 1553-1557.
34. Von Recum AF, Campbell CE,. United States Patent 5,011,494. April 30, 1991.
35. Stokes K, Bornzin G,. The electrode-biointerface: Stimulation. In:, Barold SS, (ed.): Modern Cardiac Pacing. New York, Futura Publishing, 1985, pp. 33-77.
36. Cameron J, Mond H, Ciddor G, Harper K, McKie J,. Stiffness of the distal tip of bipolar pacing leads. Pacing Clin Electrophysiol 1990; 13: 1915-1920.
37. Mond HG,. Letter to the editor. Pacing Clin Electrophysiol 2008; 31: 517.
38. Karpawich P, Stokes KB, Helland JR, Justice CD, Roskamp JO,. A new low threshold platinized epicardial pacing electrode: Comparative evaluation in immature canines. Pacing Clin Electrophysiol 1988; 11: 1139-1148.
39. Guerola M, Lindegren U,. Clinical evaluation of membrane-coated 3,5 mm2 porous titanium nitride electrodes. In: Aubert AE, Ector H, Stroobandt R (eds.): Euro-pace '93. Ferrara, Italy, Monduzzi Editore, 1993, pp. 447-450.
40. Zhdanov A,. Clinical experience in small area tip bipolar leads. In:, Antonioli A, (ed.): Proceedings of the 3rd International Symposium on Pacemaker Leads. Ferrara, Italy, Monduzzi Editore, 1997, pp. 285-288.
41. Greco OT, Ardito RV, Martinelli M, Medeiros PT, Mateos JCP, Kormann DS,. Sweet Tip Rx: A new type of atrial active fixation lead (abstract). Pacing Clin Electrophysiol 1997; 20: 1462.
42. Hughes H, Brownlee R, Tyres F,. Failures of demand pacing with small surface area electrodes. Circulation 1976; 54: 128-132.
43. Furman S, Hurzeler P, Parker B,. Clinical thresholds of endocardial cardiac stimulation: A long-term study. J Surg Res 1975; 19: 149-155.
44. Stokes K,. Do small electrodes have good sensing? (abstract). Pacing Clin Electrophysiol 1995; 18: 1774.
45. Wood M, Swerdlow C, Olson WH,. Sensing and arrhythmia detection by implantable devices. In:, Ellenbogen KA, Kay GN, Wilkoff BL, (eds.): Clinical Pacing and Defibrillation, 2nd Ed. Philadelphia, PA, WB Saunders, 2000, pp. 78-79.
46. Mond H, Stokes KB,. The electrode-tissue interface: The revolutionary role of steroid-elution. Pacing Clin Electrophysiol 1992; 15: 95-107.
47. Till JA, Jones S, Rowland E,. Clinical experience with a steroid-eluting lead in children (abstract). Circulation 1989: 80: II-389.
48. Luceri RM, Furman S, Hurzeler R, Escher DJ,. Threshold behaviour of electrodes in long-term pacing. Am J Cardiol 1977; 40: 184-188.
49. Hua W, Mond H, Sparks P,. The clinical performance of three designs of atrial pacing leads from a single manufacturer: The value of steroid-elution. Eur J C P E 1996; 6: 99-103.
50. Han J, De Jalon PG, Moe GK,. Adrenergic effects on ventricular vulnerability. Circ Res 1964; 14: 516-524.
51. Lee D, Greenspan K, Edmonds RE, Fisch C,. The effect of electrolyte requirement of cardiac pacemakers (abstract). Circulation 1968; 38 (Suppl V1): 125.
52. Walker WJ,. Serum potassium levels and myocardial threshold of excitability. Letter to the Editor. JAMA 1974; 228: 1638.
53. Beanlands DS, Akyurekli Y, Keon WJ,. Prednisone in the management of exit block. In:, Meere C, (ed.): Proceedings of the VIth World Symposium on Cardiac Pacing. Montreal, Canada, Laplante and Langevin, 1979, Chapter 18-3.
54. Mowry FM, Judge RD, Preston TA, Morris JD,. Identification and management of exit block in patients with implanted pacemakers (abstract). Circulation 1965; 31 and 32: I-157.
55. Folkman J, Long D,. Drugs and pacemakers in the treatment of heart block. Annals N Y Acad Sci 1964; 111: 857-868.
56. Brewer G, McAuslan BR, Skalsky M, Mathivanar,. Initial screening of bio-active agents with potential to reduce stimulation threshold (abstract). Pacing Clin Electrophysiol 1988; 11: 509.
57. Kruse IM,. Long-term performance of endocardial leads with steroid-eluting electrodes. Pacing Clin Electrophysiol 1986; 9: 1217-1219.
58. Mond HG,. Development of low stimulation threshold, low-polarization electrodes. In:, Barold SS, Mugica J, (eds.): New Perspectives in Cardiac Pacing, Vol. 2. Mount Kisco, New York, Futura Publishing Company, Inc., 1991, 133-162.
59. 2): 158 cases (abstract). Pacing Clin Electrophysiol 1997; 20: 1443.
60. Hua W, Mond H, Strathmore N,. Chronic steroid-eluting lead performance: A comparison of atrial and ventricular pacing. Pacing Clin Electrophysiol 1997; 20: 17-24.
61. Mond H, Hua W, Wang CC,. Atrial pacing leads: The clinical contribution of steroid-elution. Pacing Clin Electrophysiol 1995; 18: 1601-1608.
62. Stokes K, Church T,. The elimination of exit block as a pacing complication using a transvenous steroid-eluting lead (abstract). Pacing Clin Electrophysiol 1987; 10: 748.
63. Mond H, Stokes K, Helland J, Grigg L, Kertes P, Pate B, Hunt D,. The porous titanium steroid-eluting electrode: A double blind study assessing the stimulating threshold effects of steroid. Pacing Clin Electrophysiol 1988; 11: 214-219.
64. Mond H, Stokes KB,. The steroid-eluting electrode: A 10-year experience. Pacing Clin Electrophysiol 1997; 19: 1016-1020.
65. Radovsky AS, Van Vleet JF, Stokes KB, Tacker WA Jr,. Paired comparisons of steroid-eluting and nonsteroid endocardial pacemaker leads in dogs: Electrical performance and morthologic alterations. Pacing Clin Electrophysiol 1988; 11: 1085-1094.
66. Robbins SL, Cotran RS, Kumar V,. Inflammation and repair. In: Pathologic Basis of Disease. Philadelphia, PA, WB Saunders, 1984, pp. 40-84.
67. Anderson JA,. Inflammatory response to implants, American Society for Artificial Internal Organs. ASAIO 1988; II: 101-107.
68. Anderson JM, Rodrigues A, Chang DT,. Foreign body reaction to biomaterials. Seminars Immunol 2008; 20: 86-100.
69. Henson PM,. The immunologic release of constituents from neutrophil leukocytes I. The role of antibody and complement on non-phagocytosable surfaces or phagocytosable particles. J Immunol 1971; 107: 1535-1546.
70. Henson PM,. The immunological release of constituents from neutrophil leukocytes II: Mechanisms of release during phagocytosis to non-phagocytosable surfaces. J Immunol 1971; 107: 1547-1557.
71. Henson PM,. Mechanisms of exocytosis in phagocytic inflammatory cells. Ann J Pathol 1980; 101: 494-514.
72. Zhao Q, Agger MP, Fitzpatrick M, Anderson JM, Hiltner A, Stokes K, Urbanski P,. Cellular interactions with biomaterials: In vivo cracking of pre-stressed Pellethane 2363-80A. J Biomed Mater Res 1990; 24: 621-637.
73. Stokes K, Kay N,. Artificial electrical stimulation. In:, Ellenbogen K, Kay M, Wilkoff B, (eds.): Clinical Cardiac pacing and Defibrillation, 2nd Ed. Philadelphia, PA, WB Saunders, 2000, pp. 17-52.
74. Preston T, Judge RD,. Alteration of pacemaker threshold by drug and physiological factors. Ann NY Acad Sci 1969; 167: 686-692.
75. Benditt, DG, Kriett, JM, Ryberg, C, Gornick, CC, Stokes, KB, Detloff, BLS,. Cellular electrophysiologic effects of dexamethasone sodium phosphate: Implications for cardiac stimulation with steroid-eluting electrodes. Intl J Cardiol 1989; 22: 67-73.
76. Saxonhouse SJ, Conti JB, Curtis AB,. Current of injury predicts adequate lead fixation in permanent pacemaker/defibrillation leads. J Am Coll Cardiol 2006; 45: 412-417.
77. Kistler PM, Kalman JM, Fynn SP, Singarayar S, Roberts-Thomson KC, Lindsay CB, Khong U, et al. Rapid decline in acute stimulation thresholds with steroid-eluting active fixation pacing leads. Pacing Clin Electrophysiol 2005; 28: 903-909.
78. Cornacchia D, Fabbri M, Maresta A, Nigro P, Sorrentino F, Puglisi A, Ricci R, et al. Effect of steroid-eluting vs. conventional electrodes on propafanone-induced rise in chronic ventricular pacing threshold. Pacing Clin Electrophysiol 1993; 16: 2279-2284.
79. Stevens SK, Haffajee CI, Naccarelli GV, Schwartz KM, Luceri RM, Packer DL, Rubin AM, et al. Effects of oral propafenone on defibrillation and pacing thresholds in patients receiving implantable cardioverter-defibrillators. J Am Coll Cardiol 1996; 28: 418-422.
80. Shepard R, Kim J, Colvin E, Slabaugh J, Epstein A, Bargeron L,. Pacing threshold spikes months and years after implant (abstract). Pacing Clin Electrophysiol 1991; 14: 694.
81. Hiller K, Rothschild JM, Fudge W, Kieser TM, Maitland A, Gillis AM,. A randomized comparison of a bipolar steroid-eluting lead and a bipolar porous platinum coated titanium lead (abstract). Pacing Clin Electrophysiol 1991; 14: 695.
82. Stokes K, Bird T,. A new efficient Nanotip lead. Pacing Clin Electrophysiol 1990; 13: 1901-1905.
83. Anderson, Mathivanar R, Skalsky M, Tunstell A, Ng M, Harman D,. Active fixation leads-long term threshold reduction using a drug-infused ceramic collar. Pacing Clin Electrophysiol 1991; 14: 1767-1771.
84. Mathivanar R, Anderson N, Harman D, Skalsky M, NG M,. In vivo elution of drug eluting ceramic leads with a reduced dose of dexamethasone sodium phosphate. Pacing Clin Electrophysiol 1990; 13: 1883-1886.
85. Crossley GH, Brinker JA, Reynolds D,. Steroid elution improves stimulation threshold in an active-fixation in atrial permanent pacing lead (abstract). Circulation 1995; 92: 2935.
86. Kistler PM, Liew G, Mond HG,. Long-term performance of active-fixation pacing leads: A prospective study. Pacing Clin Electrophysiol 2006; 29: 226-230.
87. Stokes KB,. Preliminary studies on a new steroid-eluting epicardial electrode. Pacing Clin Electrophysiol 1988; 11: 1797-1803.
88. Karpawich PP, Hakimi M, Arciniegas E,. Improved chronic epicardial pacing in children: Steroid contribution to porous platinised electrodes. Pacing Clin Electrophysiol 1992; 15: 1151-1157.
89. Bauersfeld U, Przibille O, Gajic Z, Fåhraeus T, Kampmann C, Rahn-Schönbeck M, Schüller H,. Alternative to the transvenous approach in pediatric pacing: Long-term experiences with bipolar epicardial pacing leads. Herzschrittmachertherapie und Elektrophysiologie 2001; 12: 158-162.
90. Mond HG, Grenz D,. Implantable transvenous pacing leads: The shape of things to come. Pacing Clin Electrophysiol 2004; 27: 887-893.
91. Martindale. The Complete Drug Reference. London, Pharmaceutical Press, 1999, p. 1037.
92. Hall R,. Proceed. Int. Symp. Cont Rel Bioact Mater 2000; 27:Abstract # 6314.
93. Singarayar S, Kistler PM, De Winter C, Mond H,. A comparative study of the action of dexamethasone sodium phosphate and dexamethasone acetate in steroid-eluting pacemaker leads. Pacing Clin Electrophysiol 2005; 28: 311-315.
94. Gammage MD, Lieberman R, Yee R, Manolis AS, Compton SJ, Khazen C, Schaaf K, et al. Multi-center clinical experience with a lumenless catheter-delivered, bipolar, permanent pacemaker lead: Implant safety and electrical performance. Pacing Clinical Electrophysiol 2006; 29: 858-865.
95. Cantu F, De Filippo P, Gabbarini F, Borghi A, Brambilla R, Ferrero P, Comisso J, et al. Selective-site pacing in paediatric patients: A new application of the Select Secure system. Europace 2009; 11: 601-606.