Human blood IgM 'memory' B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire
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Deficiency of somatic hypermutation of the antibody light chain is associated with increased frequency of severe respiratory tract infection in common variable immunodeficiency
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B-cell replication history and somatic hypermutation status identify distinct pathophysiologic backgrounds in common variable immunodeficiency
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Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways
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Defect in IgV gene somatic hypermutation in common variable immuno-deficiency syndrome
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Impaired antibody affinity maturation process characterizes a subset of patients with common variable immunodeficiency
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