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Volumn 28, Issue 5, 2014, Pages 1238-1242

Levosimendan increases bleeding risk after heart valve surgery: A retrospective analysis of a randomized trial

Author keywords

cardiac surgery; cardiac tamponade; heart valve surgery; levosimendan; platelet; postoperative bleeding

Indexed keywords

APROTININ; CLOPIDOGREL; LEVOSIMENDAN; PLACEBO; TRANEXAMIC ACID; WARFARIN; CARDIOTONIC AGENT; HYDRAZONE DERIVATIVE; PYRIDAZINE DERIVATIVE; SIMENDAN;

EID: 84908214497     PISSN: 10530770     EISSN: 15328422     Source Type: Journal    
DOI: 10.1053/j.jvca.2014.04.022     Document Type: Article
Times cited : (14)

References (24)
  • 1
    • 58249132859 scopus 로고    scopus 로고
    • Levosimendan facilitates weaning from cardiopulmonary bypass in patients undergoing coronary artery bypass grafting with impaired left ventricular function
    • H.I. Eriksson, J.R. Jalonen, and L.O. Heikkinen Levosimendan facilitates weaning from cardiopulmonary bypass in patients undergoing coronary artery bypass grafting with impaired left ventricular function Ann Thorac Surg 87 2009 448 454
    • (2009) Ann Thorac Surg , vol.87 , pp. 448-454
    • Eriksson, H.I.1    Jalonen, J.R.2    Heikkinen, L.O.3
  • 2
    • 67650545459 scopus 로고    scopus 로고
    • Levosimendan reduces cardiac troponin release after cardiac surgery: A meta-analysis of randomized controlled studies
    • A. Zangrillo, G. Biondi-Zoccai, and A. Mizzi Levosimendan reduces cardiac troponin release after cardiac surgery: A meta-analysis of randomized controlled studies J Cardiothorac Vasc Anesth 23 2009 474 478
    • (2009) J Cardiothorac Vasc Anesth , vol.23 , pp. 474-478
    • Zangrillo, A.1    Biondi-Zoccai, G.2    Mizzi, A.3
  • 3
    • 84888296344 scopus 로고    scopus 로고
    • Effect of levosimendan on survival and adverse events after cardiac surgery. A meta-analysis
    • R.W. Harrison, V. Hasselblad, and R.H. Mehta Effect of levosimendan on survival and adverse events after cardiac surgery. A meta-analysis J Cardiothorac Vasc Anesth 27 2013 1224 1232
    • (2013) J Cardiothorac Vasc Anesth , vol.27 , pp. 1224-1232
    • Harrison, R.W.1    Hasselblad, V.2    Mehta, R.H.3
  • 4
    • 58449130982 scopus 로고    scopus 로고
    • Levosimendan pre-treatment improves outcomes in patients undergoing coronary artery bypass graft surgery
    • L. Tritapepe, V. De Santis, and D. Vitale Levosimendan pre-treatment improves outcomes in patients undergoing coronary artery bypass graft surgery Br J Anaesth 102 2009 198 204
    • (2009) Br J Anaesth , vol.102 , pp. 198-204
    • Tritapepe, L.1    De Santis, V.2    Vitale, D.3
  • 5
    • 0029098682 scopus 로고
    • Cardiac troponin C as a target protein for a novel calcium sensitizing drug, levosimendan
    • H. Haikala, J. Kaivola, and E. Nissinen Cardiac troponin C as a target protein for a novel calcium sensitizing drug, levosimendan J Mol Cell Cardiol 27 1995 1859 1866
    • (1995) J Mol Cell Cardiol , vol.27 , pp. 1859-1866
    • Haikala, H.1    Kaivola, J.2    Nissinen, E.3
  • 6
    • 0028172183 scopus 로고
    • Binding of a new Ca2+sensitizer, levosimendan, to recombinant human cardiac troponin C: A molecular modelling, fluorescent probe, and proton nuclear magnetic resonance study
    • P. Pollesello, M. Ovaska, and J. Kaivola Binding of a new Ca2+sensitizer, levosimendan, to recombinant human cardiac troponin C: A molecular modelling, fluorescent probe, and proton nuclear magnetic resonance study J Biol Chem 269 1994 28584 28590
    • (1994) J Biol Chem , vol.269 , pp. 28584-28590
    • Pollesello, P.1    Ovaska, M.2    Kaivola, J.3
  • 7
    • 0030608872 scopus 로고    scopus 로고
    • Levosimendan, a novel Ca2+sensitizer, activates the glibenclamide-sensitive K+channel in rat arterial myocytes
    • H. Yokoshiki, Y. Katsube, and M. Sunagawa Levosimendan, a novel Ca2+sensitizer, activates the glibenclamide-sensitive K+channel in rat arterial myocytes Eur J Pharmacol 333 1997 249 259
    • (1997) Eur J Pharmacol , vol.333 , pp. 249-259
    • Yokoshiki, H.1    Katsube, Y.2    Sunagawa, M.3
  • 8
    • 38349054796 scopus 로고    scopus 로고
    • Levosimendan has an inhibitory effect on platelet function
    • K. Kaptan, K. Erinc, and A. Ifran Levosimendan has an inhibitory effect on platelet function Am J Hematol 83 2008 46 49
    • (2008) Am J Hematol , vol.83 , pp. 46-49
    • Kaptan, K.1    Erinc, K.2    Ifran, A.3
  • 9
    • 84857355978 scopus 로고    scopus 로고
    • Prolonged antispasmodic effect in isolated radial artery graft and pronounced platelet inhibition induced by the inodilator drug levosimendan
    • N. Ambrus, J. Szolnoky, and P. Pollesello Prolonged antispasmodic effect in isolated radial artery graft and pronounced platelet inhibition induced by the inodilator drug levosimendan Basic Clin Pharmacol Toxicol 110 2012 269 274
    • (2012) Basic Clin Pharmacol Toxicol , vol.110 , pp. 269-274
    • Ambrus, N.1    Szolnoky, J.2    Pollesello, P.3
  • 10
    • 80052968318 scopus 로고    scopus 로고
    • Levosimendan reduces heart failure after cardiac surgery: A prospective, randomized, placebo-controlled trial
    • P. Lahtinen, O. Pitkänen, and P. Pölönen Levosimendan reduces heart failure after cardiac surgery: A prospective, randomized, placebo-controlled trial Crit Care Med 39 2011 2263 2270
    • (2011) Crit Care Med , vol.39 , pp. 2263-2270
    • Lahtinen, P.1    Pitkänen, O.2    Pölönen, P.3
  • 11
    • 84964965548 scopus 로고    scopus 로고
    • World Medical Association Declaration of Helsinki Accessed June 1, 2011
    • World Medical Association Declaration of Helsinki, Ethical Principles for Medical Research involving human subjects. Available at: http://www.wma.net/e/policy/b3.htm. Accessed June 1, 2011
    • Ethical Principles for Medical Research Involving Human Subjects
  • 12
    • 84888293444 scopus 로고    scopus 로고
    • Transfusion of allogeneic blood products in proximal aortic surgery with circulatory arrest: Effect of thromboelastometry-guided transfusion management
    • J. Fassl, P. Matt, and Eckstein Transfusion of allogeneic blood products in proximal aortic surgery with circulatory arrest: Effect of thromboelastometry-guided transfusion management J Cardiothorac Vasc Anesth 27 2013 1181 1188
    • (2013) J Cardiothorac Vasc Anesth , vol.27 , pp. 1181-1188
    • Fassl, J.1    Matt, P.2    Eckstein3
  • 13
    • 4844227317 scopus 로고    scopus 로고
    • The independent association of massive blood loss with mortality in cardiac surgery
    • K. Karkouti, D.N. Wijeysundera, and T.M. Yau The independent association of massive blood loss with mortality in cardiac surgery Transfusion 44 2004 1453 1462
    • (2004) Transfusion , vol.44 , pp. 1453-1462
    • Karkouti, K.1    Wijeysundera, D.N.2    Yau, T.M.3
  • 14
    • 33744509867 scopus 로고    scopus 로고
    • Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting
    • C.G. Koch, L. Li, and A.I. Duncan Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting Crit Care Med 34 2006 1608 1616
    • (2006) Crit Care Med , vol.34 , pp. 1608-1616
    • Koch, C.G.1    Li, L.2    Duncan, A.I.3
  • 15
    • 33646845605 scopus 로고    scopus 로고
    • Transfusion in coronary artery bypass grafting is associated with reduced long-term survival
    • C.G. Koch, L. Li, and A.I. Duncan Transfusion in coronary artery bypass grafting is associated with reduced long-term survival Ann Thorac Surg 81 2006 1650 1657
    • (2006) Ann Thorac Surg , vol.81 , pp. 1650-1657
    • Koch, C.G.1    Li, L.2    Duncan, A.I.3
  • 16
    • 36549084598 scopus 로고    scopus 로고
    • Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery
    • G.J. Murphy, B.C. Reeves, and C.A. Rogers Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery Circulation 116 2007 2544 2552
    • (2007) Circulation , vol.116 , pp. 2544-2552
    • Murphy, G.J.1    Reeves, B.C.2    Rogers, C.A.3
  • 17
    • 53549118289 scopus 로고    scopus 로고
    • Increased mortality, morbidity, and cost associated with red blood cell transfusion after cardiac surgery
    • B.C. Reeves, and G.J. Murphy Increased mortality, morbidity, and cost associated with red blood cell transfusion after cardiac surgery Curr Opin Anaesthesiol 21 2008 669 673
    • (2008) Curr Opin Anaesthesiol , vol.21 , pp. 669-673
    • Reeves, B.C.1    Murphy, G.J.2
  • 18
    • 79960463690 scopus 로고    scopus 로고
    • Patient blood management during cardiac surgery: Do we have enough evidence for clinical practice?
    • M. Ranucci, S. Aronson, and W. Dietrich Patient blood management during cardiac surgery: Do we have enough evidence for clinical practice? J Thorac Cardiovasc Surg 142 2011 249e1 249e32
    • (2011) J Thorac Cardiovasc Surg , vol.142 , pp. 249e1-249e32
    • Ranucci, M.1    Aronson, S.2    Dietrich, W.3
  • 19
    • 84874949613 scopus 로고    scopus 로고
    • Potential value of transfusion protocols in cardiac surgery
    • K. Görlinger, D. Dirkmann, and A.A. Hanke Potential value of transfusion protocols in cardiac surgery Curr Opin Anesthesiol 26 2013 230 243
    • (2013) Curr Opin Anesthesiol , vol.26 , pp. 230-243
    • Görlinger, K.1    Dirkmann, D.2    Hanke, A.A.3
  • 20
    • 0036795429 scopus 로고    scopus 로고
    • Pharmacokinetics of levosimendan and its metabolites during and after a 24-hour continuous infusion in patients with severe heart failure
    • M. Kivikko, S. Antila, and J. Eha Pharmacokinetics of levosimendan and its metabolites during and after a 24-hour continuous infusion in patients with severe heart failure Int J Clin Pharmacol Therap 40 2002 465 471
    • (2002) Int J Clin Pharmacol Therap , vol.40 , pp. 465-471
    • Kivikko, M.1    Antila, S.2    Eha, J.3
  • 21
    • 0034469050 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic interactions between the novel calcium sensitiser levosimendan and warfarin
    • S. Antila, A. Jarvinen, and T. Honkanen Pharmacokinetic and pharmacodynamic interactions between the novel calcium sensitiser levosimendan and warfarin Eur J Clin Pharmacol 56 2000 705 710
    • (2000) Eur J Clin Pharmacol , vol.56 , pp. 705-710
    • Antila, S.1    Jarvinen, A.2    Honkanen, T.3
  • 22
    • 34548590837 scopus 로고    scopus 로고
    • The effects of vasoactive agents, platelet agonists and anticoagulation on thrombelastography
    • J. Kawasaki, N. Katori, and T. Taketomi The effects of vasoactive agents, platelet agonists and anticoagulation on thrombelastography Acta Anaesthesiol Scand 51 2007 1237 1244
    • (2007) Acta Anaesthesiol Scand , vol.51 , pp. 1237-1244
    • Kawasaki, J.1    Katori, N.2    Taketomi, T.3
  • 23
    • 0036137181 scopus 로고    scopus 로고
    • Pharmacodynamics and safety of a new calcium sensitizer, levosimendan, and its metabolites during an extended infusion in patients with severe heart failure
    • M. Kivikko, S. Antila, and J. Eha Pharmacodynamics and safety of a new calcium sensitizer, levosimendan, and its metabolites during an extended infusion in patients with severe heart failure J Clin Pharmacol 42 2002 43 51
    • (2002) J Clin Pharmacol , vol.42 , pp. 43-51
    • Kivikko, M.1    Antila, S.2    Eha, J.3
  • 24
    • 0036828707 scopus 로고    scopus 로고
    • Predictors of pericardial effusion after orthotopic heart transplantation
    • J.A. Quin, M.P. Tauriainen, and L.M. Huber Predictors of pericardial effusion after orthotopic heart transplantation J Thorac Cardiovasc Surg 124 2002 979 983
    • (2002) J Thorac Cardiovasc Surg , vol.124 , pp. 979-983
    • Quin, J.A.1    Tauriainen, M.P.2    Huber, L.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.