Chromosome therapy: Correction of large chromosomal aberrations by inducing ring chromosomes in induced Pluripotent Stem Cells (iPSCs)

Nucleus

Volumn 5, Issue 5, 2014, Pages 391-395

  Kim, Taehyun ^a   Bershteyn, Marina ^b   Wynshaw Boris, Anthony ^a,c  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Chromosome therapy; Compensatory uniparental disomy (UPD); Induced pluripotent stem cells (iPSCs); Miller Dieker Syndrome (MDS); Ring chromosomes

Indexed keywords

AGYRIA; ARTICLE; BIRTH DEFECT; CHROMOSOME 17; CHROMOSOME 21; CHROMOSOME ABERRATION; CHROMOSOME THERAPY; CLINICAL FEATURE; EMBRYO DEVELOPMENT; FIBROBLAST; FLUORESCENCE IN SITU HYBRIDIZATION; GENE SILENCING; GENE THERAPY; GENETIC DISORDER; GENOMIC INSTABILITY; GROWTH RETARDATION; HETEROZYGOSITY LOSS; HUMAN; KARYOTYPE 46, XY; KARYOTYPING; MENTAL DEFICIENCY; MILLER DIEKER SYNDROME; MUTATION; NONHUMAN; PLURIPOTENT STEM CELL; RING CHROMOSOME; STEM CELL TRANSPLANTATION; TARGETED GENE REPAIR; UNIPARENTAL DISOMY; BIOLOGICAL THERAPY; CLASSICAL LISSENCEPHALIES AND SUBCORTICAL BAND HETEROTOPIAS; CYTOLOGY; GENETICS; PROCEDURES;

CELL- AND TISSUE-BASED THERAPY; CHROMOSOME ABERRATIONS; CLASSICAL LISSENCEPHALIES AND SUBCORTICAL BAND HETEROTOPIAS; GENETIC THERAPY; HUMANS; INDUCED PLURIPOTENT STEM CELLS; RING CHROMOSOMES; UNIPARENTAL DISOMY;

EID: 84908214218     PISSN: 19491034     EISSN: 19491042     Source Type: Journal    
DOI: 10.4161/nucl.36300     Document Type: Article

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