Systematic analysis of bacterial effector-postsynaptic density 95/disc large/zonula occludens-1 (PDZ) domain interactions demonstrates Shigella OspE protein promotes protein kinase C activation via PDLIM proteins

Journal of Biological Chemistry

Volumn 289, Issue 43, 2014, Pages 30101-30113

  Yi, Chae Ryun ^a   Allen, John E ^b   Russo, Brian ^a,d   Lee, Soo Young ^c   Heindl, Jason E ^d   Baxt, Leigh A ^a   Herrera, Bobby Brooke ^a   Kahoud, Emily ^a   MacBeath, Gavin ^e   Goldberg, Marcia B ^a,d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD UNIVERSITY   (United States)

^c Program in Immunology   (United States)

^d Department of Microbiology and Immunobiology ^*  (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL EFFECTOR; DOMAIN INTERACTIONS; POSTSYNAPTIC DENSITIES; PROTEIN KINASE C ACTIVATION; SYSTEMATIC ANALYSIS;

BACTERIAL PROTEIN; PROTEIN KINASE C; PROTEIN OSPE1; PROTEIN OSPE2; PROTEIN ZO1; UNCLASSIFIED DRUG; CYTOSKELETON PROTEIN; LIM PROTEIN; MUTANT PROTEIN; PDLIM7 PROTEIN, HUMAN; PEPTIDE; PROTEIN BINDING; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ARTICLE; BINDING AFFINITY; CHLAMYDIA TRACHOMATIS; ENZYME ACTIVATION; ESCHERICHIA COLI; FOCAL ADHESION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEGIONELLA PNEUMOPHILA; NONHUMAN; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN STABILITY; PROTEIN SYNTHESIS; SALMONELLA ENTERICA; SALMONELLA TYPHIMURIUM; SHIGELLA FLEXNERI; TYPE III SECRETION SYSTEM; TYPE IV SECRETION SYSTEM; YERSINIA ENTEROCOLITICA; AMINO ACID SEQUENCE; CHEMISTRY; CONSERVED SEQUENCE; HEK293 CELL LINE; HELA CELL LINE; INTRACELLULAR SPACE; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; PROTEIN DOMAIN; PROTEIN MICROARRAY; PROTEIN MOTIF; SACCHAROMYCES CEREVISIAE; SHIGELLA; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CONSERVED SEQUENCE; CYTOSKELETAL PROTEINS; FOCAL ADHESIONS; HEK293 CELLS; HELA CELLS; HUMANS; INTRACELLULAR SPACE; LIM DOMAIN PROTEINS; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PEPTIDES; PROTEIN ARRAY ANALYSIS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN KINASE C; SACCHAROMYCES CEREVISIAE; SHIGELLA; SIGNAL TRANSDUCTION;

EID: 84908178837     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.595868     Document Type: Article

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