The effect of gender, age, and symptom severity in late-life depression on the risk of all-cause mortality: The Bambuí cohort study of aging

Depression and Anxiety

Volumn 31, Issue 9, 2014, Pages 787-795

  Diniz, Breno S ^a   Reynolds, Charles F ^b   Butters, Meryl A ^b   Dew, Mary Amanda ^b   Firmo, Josélia O A ^c   Lima Costa, Maria Fernanda ^a,c   Castro Costa, Erico ^a,c  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Cohort study; Late life depression; Mortality; Risk factor

Indexed keywords

AGE; AGED; AGING; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FOLLOW UP; GENDER; GENERAL HEALTH QUESTIONNAIRE; GERIATRIC DEPRESSION SCALE; HAZARD RATIO; HUMAN; LATE LIFE DEPRESSION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PROSPECTIVE STUDY; RISK ASSESSMENT; SOCIAL STATUS; BRAZIL; DEPRESSION; MIDDLE AGED; RISK FACTOR; SEVERITY OF ILLNESS INDEX; SEX DIFFERENCE; VERY ELDERLY;

AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; BRAZIL; COHORT STUDIES; DEPRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SEX FACTORS;

EID: 84908145095     PISSN: 10914269     EISSN: 15206394     Source Type: Journal    
DOI: 10.1002/da.22226     Document Type: Article

References (53)

1. Viana MC, Andrade LH. Lifetime Prevalence, age and gender distribution and age-of-onset of psychiatric disorders in the Sao Paulo Metropolitan Area, Brazil: results from the Sao Paulo Megacity Mental Health Survey. Rev Bras Psiquiatr 2012;34:249-260.
2. Byers AL, Yaffe K, Covinsky KE, Friedman MB, Bruce ML. High occurrence of mood and anxiety disorders among older adults: The National Comorbidity Survey Replication. Arch Gen Psychiatry 2010;67:489-496.
3. Butters MA, Whyte EM, Nebes RD, et al. The nature and determinants of neuropsychological functioning in late-life depression. Arch Gen Psychiatry 2004;61:587-595.
4. Yen YC, Rebok GW, Gallo JJ, Jones RN, Tennstedt SL. Depressive symptoms impair everyday problem-solving ability through cognitive abilities in late life. Am J Geriatr Psychiatry 2011;19:142-150.
5. Diniz BS, Butters MA, Albert SM, Dew MA, Reynolds CF, 3rd. Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies. Br J Psychiatry 2013;202:329-335.
6. Gallegos-Carrillo K, Garcia-Pena C, Mudgal J, Romero X, Duran-Arenas L, Salmeron J. Role of depressive symptoms and comorbid chronic disease on health-related quality of life among community-dwelling older adults. J Psychosom Res 2009;66:127-135.
7. Lyness JM, Niculescu A, Tu X, Reynolds CF, 3rd, Caine ED. The relationship of medical comorbidity and depression in older, primary care patients. Psychosomatics 2006;47: 435-439.
8. Almeida OP, Alfonso H, Hankey GJ, Flicker L. Depression, antidepressant use and mortality in later life: the Health In Men Study. PLoS One 2010;5:e11266.
9. Kohler S, Verhey F, Weyerer S, et al. Depression, non-fatal stroke and all-cause mortality in old age: A prospective cohort study of primary care patients. J Affect Disord 2013;150(1):63-69. doi: 10.1016/j.jad.2013.02.020.
10. Sun W, Schooling CM, Chan WM, Ho KS, Lam TH. The association between depressive symptoms andmortality among Chinese elderly: a Hong Kong cohort study. J Gerontol A Biol Sci Med Sci. 2011;66:459-466.
11. Fredman L, Magaziner J, Hebel JR, Hawkes W, Zimmerman SI. Depressive symptoms and 6-year mortality among elderly community-dwelling women. Epidemiology 1999;10: 54-59.
12. Penninx BW, Geerlings SW, Deeg DJ, van Eijk JT, van Tilburg W, Beekman AT. Minor and major depression and the risk of death in older persons. Arch Gen Psychiatry 1999;56:889-895.
13. Hybels CF, Pieper CF, Blazer DG. Sex differences in the relationship between subthreshold depression and mortality in a community sample of older adults. Am J Geriatr Psychiatry 2002;10:283-291.
14. Fuhrer R, Dufouil C, Antonucci TC, Shipley MJ, Helmer C, Dartigues JF. Psychological disorder andmortality in French older adults: do social relations modify the association? Am J Epidemiol 1999;149:116-126.
15. Schoevers RA, Geerlings MI, Beekman AT, et al. Association of depression and gender with mortality in old age. Results from the Amsterdam Study of the Elderly (AMSTEL). Br J Psychiatry 2000;177:336-342.
16. JeongHG, Lee JJ, Lee SB, et al. Role of severity and gender in the association between late-life depression and all-cause mortality. Int Psychogeriatr 2013;25:677-684.
17. Ryan J, Carriere I, Ritchie K, et al. Late-life depression and mortality: influence of gender and antidepressant use. Br J Psychiatry 2008;192:12-18.
18. Cuijpers P, Vogelzangs N, Twisk J, Kleiboer A, Li J, Penninx BW. Differential mortality rates in major and subthreshold depression: meta-analysis of studies that measured both. Br J Psychiatry 2013;202:22-27.
19. Diniz BS, Talib LL, Joaquim HP, de Paula VR, Gattaz WF, Forlenza OV. Platelet GSK3B activity in patients with latelife depression: marker of depressive episode severity and cognitive impairment? World J Biol Psychiatry 2011;12: 216-222.
20. Gorman JM. Gender differences in depression and response to psychotropic medication. Gender Med 2006;3:93-109.
21. Vaccarino V, Badimon L, Corti R, et al. Ischaemic heart disease in women: are there sex differences in pathophysiology and risk factors? Position paper from the working group on coronary pathophysiology and microcirculation of the European Society of Cardiology. Cardiovascular Res 2011;90:9-17.
22. Fu CC, Lee YM, Chen JD. Association between depressive symptoms and twelve-year mortality among elderly in a rural community in Taiwan. J Formos Med Assoc 2003;102: 234-239.
23. Jotheeswaran AT, Williams JD, Prince MJ. Predictors of mortality among elderly people living in a south Indian urban community; a 10/66 Dementia Research Group prospective population-based cohort study. BMC Public Health 2010;10: 366.
24. Lima-Costa MF, Firmo JO, Uchoa E. Cohort profile: the Bambui (Brazil) Cohort Study of Ageing. Int J Epidemiol 2011;40:862-867.
25. Costa MF, Uchoa E, Guerra HL, Firmo JO, Vidigal PG, Barreto SM. The Bambui health and ageing study (BHAS): methodological approach and preliminary results of a populationbased cohort study of the elderly in Brazil. Rev Saude Publica 2000;34:126-135.
26. Goldberg DP, Blackwell B. Psychiatric illness in general practice. A detailed study using a new method of case identification. BMJ 1970;1:439-443.
27. Costa E, Barreto SM, Uchoa E, Firmo JO, Lima-Costa MF, Prince M. Is the GDS-30 better than the GHQ-12 for screening depression in elderly people in the community? The Bambui Health Aging Study (BHAS). Int Psychogeriatr 2006;18: 493-503.
28. Katz S, DownsTD, Cash HR,Grotz RC.Progress in development of the index of ADL. Gerontologist 1970;10:20-30.
29. Expert Committee on the Diagnosis and Classification ofDiabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 2003;26(Suppl 1):S5-S20.
30. Chobanian AV, Bakris GL, Black HR, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 2003;42:1206-1252.
31. Castro-Costa E, Fuzikawa C, Uchoa E, Firmo JO, Lima-Costa MF. Norms for the mini-mental state examination: adjustment of the cut-off point in population-based studies (evidences from the Bambú health aging study). ArqNeuropsiquiatr 2008;66:524-528.
32. Li N, Pang L, Chen G, Song X, Zhang J, Zheng X. Risk factors for depression in older adults in Beijing. Can J Psychiatry 2011;56:466-473.
33. vanGool CH, Kempen GI, Penninx BW,Deeg DJ, Beekman AT, van Eijk JT. Relationship between changes in depressive symptoms and unhealthy lifestyles in late middle aged and older persons: results from the Longitudinal Aging Study Amsterdam. Age Ageing 2003;32:81-87.
34. Wong SY, Mercer SW, Woo J, Leung J. The influence of multi-morbidity and self-reported socio-economic standing on the prevalence of depression in an elderly Hong Kong population. BMC Public Health 2008;8:119.
35. Candore G, Caruso C, Jirillo E, Magrone T, Vasto S. Low grade inflammation as a common pathogenetic denominator in agerelated diseases: novel drug targets for anti-ageing strategies and successful ageing achievement. Curr Pharm Des 2010;16:584-596.
36. Rathcke CN, Raymond I, Kistorp C, Hildebrandt P, Faber J, Vestergaard H. Low grade inflammation as measured by levels of YKL-40: association with an increased overall and cardiovascular mortality rate in an elderly population. Int J Cardiol 2010;143:35-42.
37. Diniz BS, Teixeira AL, Talib LL, Mendonca VA, Gattaz WF, Forlenza OV. Increased soluble TNF receptor 2 in antidepressant-free patients with late-life depression. J Psychiatr Res 2010;44:917-920.
38. Diniz BS, Teixeira AL, Campos AC, et al. Reduced serum levels of adiponectin in elderly patients with major depression. J Psychiatr Res 2012;46:1081-1085.
39. Wium-AndersenMK, Orsted DD, Nielsen SF, Nordestgaard BG. Elevated C-reactive protein levels, psychological distress, and depression in 73, 131 individuals. JAMA Psychiatry 2013;70:176-184.
40. PenninxBW,BeekmanAT, Bandinelli S, et al. Late-life depressive symptoms are associated with both hyperactivity and hypoactivity of the hypothalamo-pituitary-adrenal axis. Am J Geriatr Psychiatry 2007;15:522-529.
41. Dimopoulos N, Piperi C, Psarra V, Lea RW, Kalofoutis A. Increased plasma levels of 8-iso-PGF2alpha and IL-6 in an elderly population with depression. Psychiatry Res 2008;161:59-66.
42. Diniz BS, Teixeira AL, Machado-Vieira R, Talib LL, GattazWF, Forlenza OV. Reduced serum nerve growth factor in patients with late-life depression. Am J Geriatr Psychiatry 2013;21:493-496.
43. Wolkowitz OM, Mellon SH, Epel ES, et al. Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress-preliminary findings. PLoS One 2011;6:e17837.
44. Juster RP, McEwen BS, Lupien SJ. Allostatic load biomarkers of chronic stress and impact on health and cognition. Neurosci Biobehav Rev 2010;35:2-16.
45. McKinney BC, Oh H, Sibille E. Age-by-disease biological interactions: implications for late-life depression. Front Genet 2012;3:237.
46. Hidalgo CA, Blumm N, Barabasi AL, Christakis NA. A dynamic network approach for the study of human phenotypes. PLoSComput Biol 2009;5:e1000353.
47. McCaffery JM, Frasure-Smith N, Dube MP, et al. Common genetic vulnerability to depressive symptoms and coronary artery disease: a review and development of candidate genes related to inflammation and serotonin. Psychosom Med 2006;68: 187-200.
48. Alexandrino-Silva C, Wang YP, Carmen Viana M, Bulhoes RS, Martins SS, Andrade LH. Gender differences in symptomatic profiles of depression: results from the Sao PauloMegacity Mental Health Survey. J Affect Disord. May 2013;147: 355-364.
49. Mikkola TS, Gissler M, Merikukka M, Tuomikoski P, Ylikorkala O. Sex differences in age-related cardiovascular mortality. PLoS One 2013;8:e63347.
50. Reynolds CF, 3rd, Cuijpers P, Patel V, et al. Early intervention to reduce the global health and economic burden ofmajor depression in older adults. Annu Rev Public Health 2012;33:123-135.
51. Cuijpers P, Beekman AT, Reynolds CF, 3rd. Preventing depression: a global priority. JAMA 2012;307:1033-1034.
52. Gallo JJ, Morales KH, Bogner HR, et al. Long term effect of depression care management on mortality in older adults: followup of cluster randomized clinical trial in primary care. BMJ 2013;346:f2570.
53. Castro-Costa E, Lima-Costa MF, Carvalhais S, Firmo JO, Uchoa E. Factors associated with depressive symptoms measured by the 12-item General Health Questionnaire in community-dwelling older adults (The Bambú Health Aging Study). Rev Bras Psiquiatr 2008;30:104-109.